Mus musculus

181 known processes

Ccl2

chemokine (C-C motif) ligand 2

(Aliases: MCP1,AI323594,MCAF,Sigje,HC11,SMC-CF,JE,Scya2,MCP-1)

Ccl2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of monocyte chemotaxis GO:0090026 2 1.000
positive regulation of t helper 1 cell differentiation GO:0045627 4 1.000
regulation of monocyte chemotaxis GO:0090025 3 1.000
negative regulation of macrophage apoptotic process GO:2000110 3 1.000
response to interleukin 1 GO:0070555 11 1.000
dendritic cell dendrite assembly GO:0097026 2 1.000
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.999
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.999
mature natural killer cell chemotaxis GO:0035782 1 0.999
interleukin 18 mediated signaling pathway GO:0035655 2 0.999
eosinophil activation GO:0043307 1 0.999
t cell extravasation GO:0072683 4 0.999
regulation of t helper 1 cell cytokine production GO:2000554 1 0.999
positive regulation of t cell extravasation GO:2000409 2 0.999
granulocyte migration GO:0097530 43 0.998
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.998
dendritic cell chemotaxis GO:0002407 7 0.998
alpha beta t cell proliferation GO:0046633 21 0.998
t helper 1 cell cytokine production GO:0035744 1 0.998
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.998
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.998
eosinophil activation involved in immune response GO:0002278 1 0.998
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.997
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.997
t helper 2 cell cytokine production GO:0035745 4 0.997
b cell chemotaxis GO:0035754 3 0.997
regulation of natural killer cell chemotaxis GO:2000501 1 0.997
regulation of b cell chemotaxis GO:2000537 2 0.997
response to bacterial lipoprotein GO:0032493 4 0.997
regulation of dendritic cell dendrite assembly GO:2000547 2 0.997
cellular response to interleukin 18 GO:0071351 3 0.997
interleukin 12 secretion GO:0072610 3 0.996
regulation of type 2 immune response GO:0002828 18 0.996
inflammatory cell apoptotic process GO:0006925 11 0.996
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.995
regulation of alpha beta t cell proliferation GO:0046640 18 0.995
regulation of cytokine production involved in immune response GO:0002718 26 0.995
inflammatory response to wounding GO:0090594 4 0.995
natural killer cell chemotaxis GO:0035747 1 0.995
mature dendritic cell differentiation GO:0097029 3 0.995
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.994
cdc42 protein signal transduction GO:0032488 0 0.994
response to lipopolysaccharide GO:0032496 128 0.994
eosinophil degranulation GO:0043308 1 0.994
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.994
organ or tissue specific immune response GO:0002251 13 0.994
immunoglobulin production in mucosal tissue GO:0002426 3 0.993
immune effector process GO:0002252 321 0.993
antibacterial peptide secretion GO:0002779 1 0.992
regulation of t helper 2 cell cytokine production GO:2000551 3 0.992
response to interferon gamma GO:0034341 34 0.991
cellular response to molecule of bacterial origin GO:0071219 83 0.991
regulation of t cell extravasation GO:2000407 3 0.990
cellular response to cytokine stimulus GO:0071345 189 0.990
regulation of eosinophil migration GO:2000416 2 0.989
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.987
positive regulation of inflammatory response GO:0050729 47 0.987
regulation of neutrophil chemotaxis GO:0090022 14 0.987
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.987
positive regulation of b cell chemotaxis GO:2000538 2 0.987
regulation of dendritic cell chemotaxis GO:2000508 1 0.987
cellular response to biotic stimulus GO:0071216 92 0.986
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.986
positive regulation of type 2 immune response GO:0002830 9 0.985
cellular response to lipid GO:0071396 145 0.984
regulation of inflammatory response GO:0050727 147 0.983
defense response to other organism GO:0098542 197 0.983
regulation of t helper 1 cell differentiation GO:0045625 7 0.982
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.981
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.978
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.978
response to interleukin 4 GO:0070670 23 0.978
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.977
positive regulation of thymocyte migration GO:2000412 2 0.976
positive regulation of immunological synapse formation GO:2000522 1 0.976
interleukin 1 secretion GO:0050701 16 0.975
monocyte extravasation GO:0035696 2 0.975
detection of molecule of bacterial origin GO:0032490 2 0.975
negative regulation of myoblast differentiation GO:0045662 18 0.975
leukocyte mediated immunity GO:0002443 174 0.974
positive regulation of defense response GO:0031349 124 0.974
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.974
i kappab kinase nf kappab signaling GO:0007249 85 0.973
response to tumor necrosis factor GO:0034612 26 0.973
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.972
cellular response to peptidoglycan GO:0071224 4 0.971
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.971
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 6 0.970
inflammatory response GO:0006954 244 0.970
regulation of thymocyte migration GO:2000410 2 0.970
lymphocyte migration GO:0072676 26 0.970
positive regulation of neutrophil chemotaxis GO:0090023 12 0.969
positive regulation of eosinophil migration GO:2000418 2 0.969
regulation of monocyte extravasation GO:2000437 2 0.966
positive regulation of t cell proliferation GO:0042102 52 0.965
positive regulation of granulocyte chemotaxis GO:0071624 12 0.964
t cell proliferation GO:0042098 120 0.964
cellular response to lipopolysaccharide GO:0071222 77 0.962
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.961
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.960
cellular response to interleukin 4 GO:0071353 21 0.960
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.959
positive regulation of neuron apoptotic process GO:0043525 25 0.958
defense response to gram negative bacterium GO:0050829 28 0.958
regulation of acute inflammatory response GO:0002673 27 0.958
microglial cell activation involved in immune response GO:0002282 1 0.958
cytokine mediated signaling pathway GO:0019221 115 0.957
regulation of nucleotide binding oligomerization domain containing signaling pathway GO:0070424 3 0.956
leukocyte apoptotic process GO:0071887 71 0.956
regulation of antigen processing and presentation GO:0002577 10 0.955
positive regulation of cytokine production involved in immune response GO:0002720 19 0.955
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.955
calcium ion transport into cytosol GO:0060402 48 0.954
regulation of interleukin 1 secretion GO:0050704 15 0.954
adaptive immune response GO:0002250 155 0.954
wound healing involved in inflammatory response GO:0002246 4 0.953
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.952
calcium ion transport GO:0006816 159 0.952
myeloid cell apoptotic process GO:0033028 22 0.951
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.950
regulation of mapk cascade GO:0043408 248 0.950
modification of morphology or physiology of other organism GO:0035821 18 0.948
astrocyte cell migration GO:0043615 3 0.948
modulation by symbiont of defense related host nitric oxide production GO:0052163 1 0.948
positive regulation of t helper 1 type immune response GO:0002827 12 0.948
cytokine production GO:0001816 319 0.947
regulation of rho gtpase activity GO:0032319 58 0.947
positive regulation of leukocyte proliferation GO:0070665 73 0.945
interspecies interaction between organisms GO:0044419 83 0.944
innate immune response GO:0045087 157 0.944
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.944
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070428 3 0.944
lymphocyte activation involved in immune response GO:0002285 93 0.943
response to interleukin 18 GO:0070673 4 0.942
antibacterial peptide production GO:0002778 2 0.941
chemokine mediated signaling pathway GO:0070098 17 0.940
microglial cell activation GO:0001774 3 0.940
response to molecule of bacterial origin GO:0002237 143 0.940
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.939
epithelial cell proliferation GO:0050673 174 0.939
chemokine production GO:0032602 34 0.938
t cell chemotaxis GO:0010818 6 0.937
positive regulation of lymphocyte migration GO:2000403 11 0.937
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.936
regulation of interleukin 1 production GO:0032652 26 0.935
macrophage chemotaxis GO:0048246 14 0.935
regulation of neutrophil migration GO:1902622 14 0.934
cell cell recognition GO:0009988 44 0.934
positive regulation of interleukin 1 production GO:0032732 17 0.933
positive regulation of jnk cascade GO:0046330 46 0.931
reactive nitrogen species metabolic process GO:2001057 0 0.930
positive regulation of interleukin 12 production GO:0032735 21 0.930
monocyte chemotaxis GO:0002548 5 0.928
positive regulation of immune effector process GO:0002699 107 0.927
t cell activation GO:0042110 289 0.927
lymphocyte chemotaxis GO:0048247 10 0.927
positive regulation of mapk cascade GO:0043410 170 0.926
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.926
positive regulation of cell activation GO:0050867 158 0.926
cytokine production involved in immune response GO:0002367 34 0.926
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.924
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.924
regulation of leukocyte proliferation GO:0070663 121 0.924
positive regulation of t cell costimulation GO:2000525 2 0.922
alpha beta t cell activation involved in immune response GO:0002287 31 0.920
positive regulation of response to wounding GO:1903036 66 0.920
cellular calcium ion homeostasis GO:0006874 119 0.920
cellular chemical homeostasis GO:0055082 215 0.919
eosinophil mediated immunity GO:0002447 1 0.919
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.919
positive regulation of lymphocyte proliferation GO:0050671 70 0.919
divalent inorganic cation homeostasis GO:0072507 138 0.916
regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070432 3 0.915
dendritic cell differentiation GO:0097028 26 0.913
angiogenesis GO:0001525 201 0.913
positive regulation of t cell migration GO:2000406 10 0.913
divalent metal ion transport GO:0070838 172 0.912
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.912
myeloid leukocyte migration GO:0097529 57 0.912
positive regulation of rho gtpase activity GO:0032321 41 0.912
leukocyte migration GO:0050900 124 0.907
regulation of angiogenesis GO:0045765 81 0.900
t helper 17 cell chemotaxis GO:0035705 1 0.898
regulation of alpha beta t cell activation GO:0046634 53 0.898
regulation of t helper 1 type immune response GO:0002825 17 0.897
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.897
positive regulation of protein secretion GO:0050714 52 0.896
regulation of gtp catabolic process GO:0033124 113 0.894
immunoglobulin mediated immune response GO:0016064 69 0.894
regulation of b cell mediated immunity GO:0002712 37 0.893
myeloid leukocyte differentiation GO:0002573 119 0.892
positive regulation of adaptive immune response GO:0002821 61 0.892
neutrophil migration GO:1990266 37 0.891
regulation of cytokine production GO:0001817 266 0.889
positive regulation of protein modification process GO:0031401 299 0.888
blood vessel morphogenesis GO:0048514 285 0.888
defense response to bacterium GO:0042742 119 0.886
cell chemotaxis GO:0060326 81 0.886
stress activated mapk cascade GO:0051403 80 0.883
positive regulation of tumor necrosis factor production GO:0032760 30 0.882
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.882
cytosolic calcium ion transport GO:0060401 48 0.880
positive regulation of neutrophil migration GO:1902624 12 0.880
t cell costimulation GO:0031295 14 0.878
cation transport GO:0006812 399 0.877
thymocyte migration GO:0072679 2 0.874
positive regulation of interleukin 1 secretion GO:0050716 14 0.873
t cell activation involved in immune response GO:0002286 43 0.871
purine nucleoside metabolic process GO:0042278 241 0.871
regulation of defense response GO:0031347 233 0.868
eosinophil migration GO:0072677 3 0.868
positive regulation of protein phosphorylation GO:0001934 242 0.861
positive regulation of cytokine production GO:0001819 174 0.861
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.860
positive regulation of acute inflammatory response GO:0002675 16 0.859
positive regulation of b cell mediated immunity GO:0002714 26 0.859
positive regulation of angiogenesis GO:0045766 46 0.858
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.858
sequestering of metal ion GO:0051238 19 0.857
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.857
response to molecule of fungal origin GO:0002238 4 0.856
cation homeostasis GO:0055080 212 0.855
production of molecular mediator of immune response GO:0002440 103 0.854
morphogenesis of a branching structure GO:0001763 203 0.853
regulation of stress activated mapk cascade GO:0032872 69 0.853
regulation of cell migration GO:0030334 219 0.852
regulation of cellular response to stress GO:0080135 159 0.851
lymphocyte differentiation GO:0030098 242 0.850
regulation of neutrophil mediated killing of fungus GO:0070953 1 0.850
positive regulation of programmed cell death GO:0043068 218 0.849
positive regulation of cellular amine metabolic process GO:0033240 5 0.846
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.845
regulation of response to wounding GO:1903034 189 0.844
regulation of adaptive immune response GO:0002819 90 0.841
positive regulation of leukocyte mediated immunity GO:0002705 70 0.840
regulation of interleukin 1 beta secretion GO:0050706 15 0.840
immune complex clearance by monocytes and macrophages GO:0002436 2 0.838
macrophage apoptotic process GO:0071888 7 0.838
neuron death GO:0070997 154 0.838
type 2 immune response GO:0042092 23 0.837
response to low density lipoprotein particle GO:0055098 2 0.833
small gtpase mediated signal transduction GO:0007264 97 0.832
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070430 1 0.831
regulation of leukocyte mediated immunity GO:0002703 104 0.830
regulation of protein transport GO:0051223 163 0.828
negative regulation of homeostatic process GO:0032845 71 0.827
granulocyte chemotaxis GO:0071621 39 0.827
regulation of cellular amino acid metabolic process GO:0006521 5 0.825
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.825
t helper 1 type immune response GO:0042088 25 0.824
negative regulation of angiogenesis GO:0016525 25 0.823
negative regulation of chemokine biosynthetic process GO:0045079 2 0.820
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.819
protein secretion GO:0009306 111 0.818
neutrophil chemotaxis GO:0030593 36 0.818
cell type specific apoptotic process GO:0097285 268 0.818
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.817
regulation of lymphocyte proliferation GO:0050670 117 0.814
response to alcohol GO:0097305 48 0.812
immunoglobulin production GO:0002377 73 0.812
response to amino acid GO:0043200 37 0.810
acute phase response GO:0006953 10 0.809
regulation of cellular amine metabolic process GO:0033238 20 0.807
positive regulation of cytokine secretion GO:0050715 41 0.806
positive regulation of chemokine biosynthetic process GO:0045080 6 0.803
nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070431 6 0.803
cytokine secretion GO:0050663 72 0.801
mapk cascade GO:0000165 281 0.800
cellular response to interferon gamma GO:0071346 25 0.799
helper t cell chemotaxis GO:0035704 1 0.795
response to organic cyclic compound GO:0014070 198 0.794
sequestering of calcium ion GO:0051208 18 0.794
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.790
regulation of vascular endothelial growth factor production GO:0010574 13 0.790
regulation of t helper cell differentiation GO:0045622 14 0.788
regulation of cell activation GO:0050865 289 0.787
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.785
cd4 positive alpha beta t cell activation GO:0035710 45 0.780
negative regulation of reactive oxygen species biosynthetic process GO:1903427 0 0.780
skeletal muscle fiber development GO:0048741 58 0.780
cellular ketone metabolic process GO:0042180 84 0.777
calcium ion homeostasis GO:0055074 127 0.775
positive regulation of myotube differentiation GO:0010831 24 0.774
cellular homeostasis GO:0019725 240 0.774
regulation of ras gtpase activity GO:0032318 88 0.772
regulation of interleukin 1 beta production GO:0032651 25 0.772
dendritic cell migration GO:0036336 12 0.770
positive regulation of glycoprotein biosynthetic process GO:0010560 6 0.769
positive regulation of chemotaxis GO:0050921 38 0.768
regulation of cellular ketone metabolic process GO:0010565 66 0.768
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.766
positive regulation of t cell chemotaxis GO:0010820 5 0.764
regulation of chemokine biosynthetic process GO:0045073 8 0.763
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.762
regulation of secretion GO:0051046 274 0.760
positive regulation of gtpase activity GO:0043547 85 0.758
interleukin 1 production GO:0032612 31 0.756
acute inflammatory response to antigenic stimulus GO:0002438 12 0.755
myotube differentiation GO:0014902 105 0.753
regulation of cytokine biosynthetic process GO:0042035 59 0.752
positive regulation of neutrophil mediated killing of fungus GO:0070965 1 0.752
positive regulation of cell migration GO:0030335 109 0.751
interferon beta biosynthetic process GO:0045350 4 0.750
metal ion homeostasis GO:0055065 189 0.749
myotube cell development GO:0014904 60 0.747
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.746
positive regulation of glycoprotein metabolic process GO:1903020 6 0.745
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.745
positive regulation of muscle cell differentiation GO:0051149 39 0.743
forebrain cell migration GO:0021885 58 0.742
vascular endothelial growth factor production GO:0010573 13 0.742
positive regulation of immunoglobulin production GO:0002639 28 0.740
regulation of t cell proliferation GO:0042129 92 0.740
regulation of lymphocyte migration GO:2000401 14 0.738
regulation of myotube differentiation GO:0010830 62 0.738
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.737
regulation of nucleoside metabolic process GO:0009118 130 0.734
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.734
positive regulation of epithelial cell proliferation GO:0050679 68 0.733
mammary gland duct morphogenesis GO:0060603 38 0.731
response to oxygen levels GO:0070482 62 0.731
regulation of secretion by cell GO:1903530 249 0.731
cellular metal ion homeostasis GO:0006875 151 0.731
induction by symbiont of host immune response GO:0052559 1 0.730
regulation of protein secretion GO:0050708 82 0.729
leukocyte activation involved in immune response GO:0002366 126 0.729
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.728
regulation of cellular catabolic process GO:0031329 242 0.726
alpha beta t cell differentiation GO:0046632 69 0.726
organonitrogen compound catabolic process GO:1901565 264 0.724
regulation of immunoglobulin production GO:0002637 42 0.724
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.724
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.723
antimicrobial peptide secretion GO:0002776 1 0.723
cellular response to organonitrogen compound GO:0071417 145 0.720
syncytium formation GO:0006949 43 0.719
divalent inorganic cation transport GO:0072511 178 0.717
ras protein signal transduction GO:0007265 77 0.716
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.714
positive regulation of monocyte extravasation GO:2000439 1 0.712
t helper cell differentiation GO:0042093 28 0.710
myeloid leukocyte activation GO:0002274 83 0.708
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.706
leukocyte differentiation GO:0002521 342 0.705
regulation of lymphocyte chemotaxis GO:1901623 6 0.702
positive regulation by symbiont of host immune response GO:0052556 1 0.702
response to defense related host nitric oxide production GO:0052565 2 0.698
regulation of innate immune response GO:0045088 91 0.698
regulation of immunological synapse formation GO:2000520 2 0.697
positive regulation of interleukin 18 production GO:0032741 2 0.697
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.693
defense response to gram positive bacterium GO:0050830 50 0.692
cellular response to interleukin 1 GO:0071347 8 0.691
t cell differentiation GO:0030217 174 0.691
positive regulation of interleukin 6 production GO:0032755 37 0.689
lymphocyte mediated immunity GO:0002449 139 0.688
response to organonitrogen compound GO:0010243 246 0.685
positive regulation of alpha beta t cell activation GO:0046635 39 0.682
defense response to virus GO:0051607 68 0.678
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.676
cellular response to tumor necrosis factor GO:0071356 21 0.673
regulation of t cell costimulation GO:2000523 2 0.670
leukocyte chemotaxis GO:0030595 69 0.668
regulation of cdc42 protein signal transduction GO:0032489 5 0.667
response to vitamin a GO:0033189 1 0.667
cellular divalent inorganic cation homeostasis GO:0072503 127 0.665
release of sequestered calcium ion into cytosol GO:0051209 42 0.664
b cell mediated immunity GO:0019724 71 0.661
detection of lipopolysaccharide GO:0032497 1 0.655
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.654
cellular response to bacterial lipopeptide GO:0071221 3 0.649
positive regulation of hematopoietic stem cell proliferation GO:1902035 2 0.647
regulation of lymphocyte activation GO:0051249 240 0.646
regulation of reactive oxygen species metabolic process GO:2000377 40 0.646
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.645
regulation of establishment of protein localization GO:0070201 181 0.642
cellular amino acid metabolic process GO:0006520 103 0.642
regulation of cell motility GO:2000145 236 0.642
regulation of cytokine secretion GO:0050707 61 0.641
regulation of production of molecular mediator of immune response GO:0002700 65 0.641
positive regulation of apoptotic process GO:0043065 217 0.638
response to growth factor GO:0070848 198 0.637
cell activation involved in immune response GO:0002263 126 0.637
maintenance of location GO:0051235 89 0.636
interleukin 12 production GO:0032615 32 0.634
interleukin 5 secretion GO:0072603 2 0.634
positive regulation by organism of defense response of other organism involved in symbiotic interaction GO:0052510 1 0.633
muscle fiber development GO:0048747 76 0.632
regulation of membrane potential GO:0042391 192 0.631
chronic inflammatory response to antigenic stimulus GO:0002439 3 0.630
regulation of chemotaxis GO:0050920 53 0.629
interleukin 6 biosynthetic process GO:0042226 12 0.629
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.620
regulation of vesicle mediated transport GO:0060627 139 0.614
positive regulation of stress activated mapk cascade GO:0032874 48 0.612
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.608
myeloid cell differentiation GO:0030099 233 0.605
glycosyl compound metabolic process GO:1901657 246 0.603
inflammatory response to antigenic stimulus GO:0002437 30 0.601
regulation of ion homeostasis GO:2000021 64 0.600
antibacterial peptide biosynthetic process GO:0002780 2 0.595
positive regulation of map kinase activity GO:0043406 84 0.595
positive regulation of lymphocyte activation GO:0051251 140 0.593
cytoplasmic transport GO:0016482 234 0.592
regulation of t cell activation GO:0050863 170 0.591
regulation of epithelial cell proliferation GO:0050678 141 0.585
humoral immune response GO:0006959 57 0.583
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052263 1 0.583
positive regulation of myoblast differentiation GO:0045663 8 0.582
regulation of insulin receptor signaling pathway GO:0046626 21 0.581
negative regulation of eosinophil degranulation GO:0043310 1 0.579
modulation by symbiont of host immune response GO:0052553 1 0.579
regulation of growth of symbiont in host GO:0044126 19 0.579
response to host immune response GO:0052572 3 0.578
response to lipoteichoic acid GO:0070391 6 0.576
cellular response to growth factor stimulus GO:0071363 197 0.572
regulation of jun kinase activity GO:0043506 40 0.569
positive regulation of t cell cytokine production GO:0002726 5 0.568
reactive oxygen species metabolic process GO:0072593 84 0.568
fever generation GO:0001660 7 0.565
positive regulation of kinase activity GO:0033674 155 0.565
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 5 0.563
regulation of leukocyte differentiation GO:1902105 159 0.562
sterol metabolic process GO:0016125 58 0.562
macrophage activation GO:0042116 27 0.561
response to drug GO:0042493 75 0.561
cytokine metabolic process GO:0042107 71 0.560
regulation of jnk cascade GO:0046328 62 0.559
regulation of vasculature development GO:1901342 88 0.557
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.556
negative regulation of multi organism process GO:0043901 68 0.555
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.554
guanosine containing compound metabolic process GO:1901068 144 0.552
positive regulation of leukocyte differentiation GO:1902107 86 0.551
purine ribonucleoside metabolic process GO:0046128 241 0.550
regulation of interleukin 6 production GO:0032675 55 0.550
regulation of homeostatic process GO:0032844 182 0.549
regulation of glycoprotein biosynthetic process GO:0010559 12 0.549
positive regulation of nucleoside metabolic process GO:0045979 91 0.547
branching morphogenesis of an epithelial tube GO:0048754 159 0.546
guanosine containing compound catabolic process GO:1901069 144 0.546
stress activated protein kinase signaling cascade GO:0031098 81 0.546
amine metabolic process GO:0009308 45 0.544
rho protein signal transduction GO:0007266 32 0.543
regulation of hematopoietic stem cell migration GO:2000471 1 0.542
positive regulation of t cell differentiation GO:0045582 52 0.540
regulation of striated muscle cell differentiation GO:0051153 81 0.539
regulation of leukocyte apoptotic process GO:2000106 56 0.538
muscle cell development GO:0055001 133 0.536
regulation of map kinase activity GO:0043405 120 0.535
chemokine metabolic process GO:0050755 10 0.535
cellular ion homeostasis GO:0006873 165 0.534
sensory perception of pain GO:0019233 47 0.529
lymphocyte costimulation GO:0031294 15 0.527
positive regulation of nervous system development GO:0051962 221 0.523
positive regulation of nucleotide metabolic process GO:0045981 114 0.522
erk1 and erk2 cascade GO:0070371 77 0.522
t cell migration GO:0072678 19 0.521
regulation of ras protein signal transduction GO:0046578 114 0.521
negative regulation of chemokine production GO:0032682 4 0.521
regulation of cell projection organization GO:0031344 206 0.520
chemotaxis GO:0006935 247 0.519
negative regulation of immune system process GO:0002683 209 0.518
negative regulation of interleukin 5 secretion GO:2000663 1 0.515
cytokine biosynthetic process GO:0042089 68 0.514
regulation of neutrophil mediated cytotoxicity GO:0070948 2 0.514
positive regulation of chemokine production GO:0032722 22 0.512
production of molecular mediator involved in inflammatory response GO:0002532 21 0.511
regulation of tumor necrosis factor production GO:0032680 49 0.510
antimicrobial peptide biosynthetic process GO:0002777 2 0.507
positive regulation of cd4 positive alpha beta t cell activation GO:2000516 16 0.505
regulation of nucleotide metabolic process GO:0006140 169 0.502
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.501
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction GO:0052302 1 0.498
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.498
regulation of transferase activity GO:0051338 263 0.498
striated muscle tissue development GO:0014706 293 0.498
regulation of myeloid cell apoptotic process GO:0033032 19 0.497
regulation of alpha beta t cell differentiation GO:0046637 35 0.496
t helper 17 cell lineage commitment GO:0072540 4 0.496
acute inflammatory response GO:0002526 41 0.495
positive regulation of secretion GO:0051047 130 0.495
t cell differentiation involved in immune response GO:0002292 30 0.493
phagocytosis GO:0006909 66 0.492
tumor necrosis factor production GO:0032640 50 0.491
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.484
cellular amine metabolic process GO:0044106 44 0.483
peptidyl tyrosine modification GO:0018212 145 0.481
positive regulation of hypersensitivity GO:0002885 7 0.478
positive regulation of ras gtpase activity GO:0032320 65 0.478
fatty acid derivative transport GO:1901571 14 0.478
regulation of ion transport GO:0043269 215 0.472
response to oxidative stress GO:0006979 123 0.470

Ccl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.573
sensory system disease DOID:0050155 0 0.573
disease of anatomical entity DOID:7 0 0.573
eye and adnexa disease DOID:1492 0 0.573
nervous system disease DOID:863 0 0.573
eye disease DOID:5614 0 0.573