Mus musculus

48 known processes

Ccr5

chemokine (C-C motif) receptor 5

(Aliases: CD195,Cmkbr5,AM4-7)

Ccr5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of dendritic cell chemotaxis GO:2000508 1 0.993
Mouse
eosinophil degranulation GO:0043308 1 0.993
Mouse
t cell extravasation GO:0072683 4 0.992
Mouse
positive regulation of immunological synapse formation GO:2000522 1 0.992
Mouse
positive regulation of monocyte extravasation GO:2000439 1 0.985
Mouse
interleukin 12 secretion GO:0072610 3 0.984
Mouse
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.983
Mouse
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.968
Mouse
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.967
Mouse
regulation of monocyte extravasation GO:2000437 2 0.966
Mouse
eosinophil activation GO:0043307 1 0.956
Mouse
regulation of monocyte chemotaxis GO:0090025 3 0.952
Human Mouse
myeloid cell differentiation GO:0030099 233 0.936
Mouse
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.934
Mouse
immune complex clearance by monocytes and macrophages GO:0002436 2 0.932
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.926
Human Mouse
chemokine mediated signaling pathway GO:0070098 17 0.890
microglial cell activation GO:0001774 3 0.882
Mouse
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.881
Mouse
cellular defense response GO:0006968 6 0.880
Mouse
regulation of immunological synapse formation GO:2000520 2 0.859
Mouse
eosinophil mediated immunity GO:0002447 1 0.829
Mouse
immune complex clearance GO:0002434 2 0.819
Mouse
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.815
Mouse
cation homeostasis GO:0055080 212 0.814
Human Mouse
regulation of hematopoietic stem cell migration GO:2000471 1 0.812
Mouse
helper t cell chemotaxis GO:0035704 1 0.774
Mouse
hematopoietic stem cell migration GO:0035701 1 0.772
Mouse
regulation of interleukin 1 secretion GO:0050704 15 0.771
Mouse
positive regulation of t cell extravasation GO:2000409 2 0.763
Mouse
regulation of eosinophil degranulation GO:0043309 1 0.751
Mouse
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.741
Mouse
detection of fungus GO:0016046 2 0.720
regulation of adaptive immune response GO:0002819 90 0.718
Mouse
positive regulation of neutrophil chemotaxis GO:0090023 12 0.712
Mouse
positive regulation of neutrophil migration GO:1902624 12 0.692
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.689
Mouse
response to lipopolysaccharide GO:0032496 128 0.686
Human Mouse
positive regulation of phagocytosis GO:0050766 26 0.685
negative regulation of macrophage apoptotic process GO:2000110 3 0.681
interleukin 1 secretion GO:0050701 16 0.663
Mouse
regulation of t cell costimulation GO:2000523 2 0.653
Mouse
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.639
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.633
monocyte extravasation GO:0035696 2 0.632
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.623
Human
positive regulation of defense response GO:0031349 124 0.614
Mouse
alpha beta t cell proliferation GO:0046633 21 0.600
Mouse
leukocyte proliferation GO:0070661 172 0.587
Mouse
regulation of t cell activation GO:0050863 170 0.578
Mouse
regulation of t cell proliferation GO:0042129 92 0.577
Mouse
granulocyte chemotaxis GO:0071621 39 0.551
Mouse
sequestering of calcium ion GO:0051208 18 0.549
Human Mouse
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.543
regulation of cytokine biosynthetic process GO:0042035 59 0.532
Mouse
action potential GO:0001508 78 0.529
cytokine production GO:0001816 319 0.523
Mouse
myeloid leukocyte mediated immunity GO:0002444 42 0.523
Mouse
regulation of t cell extravasation GO:2000407 3 0.514
Mouse
microglial cell activation involved in immune response GO:0002282 1 0.510
Mouse
positive regulation of cytokine production GO:0001819 174 0.507
Mouse
positive regulation of endocytosis GO:0045807 42 0.494
mature dendritic cell differentiation GO:0097029 3 0.492
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.490
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.479
Mouse
innate immune response GO:0045087 157 0.465
Mouse
dendritic cell chemotaxis GO:0002407 7 0.461
Mouse
eosinophil activation involved in immune response GO:0002278 1 0.453
Mouse
divalent metal ion transport GO:0070838 172 0.453
Human Mouse
regulation of lymphocyte activation GO:0051249 240 0.450
Mouse
sequestering of metal ion GO:0051238 19 0.447
Human Mouse
release of sequestered calcium ion into cytosol GO:0051209 42 0.444
Human Mouse
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.444
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.441
regulation of leukocyte mediated immunity GO:0002703 104 0.438
Mouse
regulation of interferon gamma production GO:0032649 57 0.437
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.436
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.431
Mouse
myeloid cell apoptotic process GO:0033028 22 0.426
glycoprotein biosynthetic process GO:0009101 89 0.424
Mouse
regulation of cell activation GO:0050865 289 0.413
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.413
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.398
neutrophil migration GO:1990266 37 0.396
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.392
lymphocyte proliferation GO:0046651 164 0.392
Mouse
inflammatory cell apoptotic process GO:0006925 11 0.390
lymphocyte differentiation GO:0030098 242 0.389
Mouse
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.381
Mouse
macrophage apoptotic process GO:0071888 7 0.378
myeloid leukocyte activation GO:0002274 83 0.377
Mouse
regulation of interleukin 1 production GO:0032652 26 0.372
Mouse
rho protein signal transduction GO:0007266 32 0.371
macrophage chemotaxis GO:0048246 14 0.370
Mouse
immune response activating signal transduction GO:0002757 116 0.370
Mouse
cellular chemical homeostasis GO:0055082 215 0.369
Human Mouse
cdc42 protein signal transduction GO:0032488 0 0.364
regulation of membrane potential GO:0042391 192 0.364
dendritic cell dendrite assembly GO:0097026 2 0.363
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.354
Mouse
regulation of protein secretion GO:0050708 82 0.347
Mouse
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.341
regulation of secretion by cell GO:1903530 249 0.340
Mouse
cytokine biosynthetic process GO:0042089 68 0.339
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.338
divalent inorganic cation homeostasis GO:0072507 138 0.334
Human Mouse
positive regulation of t cell costimulation GO:2000525 2 0.334
Mouse
immune response regulating signaling pathway GO:0002764 125 0.333
Mouse
dendritic cell antigen processing and presentation GO:0002468 7 0.327
Mouse
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.327
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.327
Mouse
positive regulation of b cell mediated immunity GO:0002714 26 0.324
mapk cascade GO:0000165 281 0.321
Human
lymphocyte mediated immunity GO:0002449 139 0.320
cell activation involved in immune response GO:0002263 126 0.320
Mouse
positive regulation of cell activation GO:0050867 158 0.319
Mouse
calcium ion transport GO:0006816 159 0.311
Human Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.309
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.307
Mouse
regulation of antigen processing and presentation GO:0002577 10 0.305
Mouse
positive regulation of macrophage chemotaxis GO:0010759 5 0.302
t cell costimulation GO:0031295 14 0.300
Mouse
regulation of interleukin 1 beta production GO:0032651 25 0.299
Mouse
negative regulation of regulated secretory pathway GO:1903306 7 0.298
Mouse
regulation of vascular endothelial growth factor production GO:0010574 13 0.298
Mouse
response to molecule of bacterial origin GO:0002237 143 0.295
Human Mouse
leukocyte degranulation GO:0043299 27 0.293
Mouse
defense response to other organism GO:0098542 197 0.293
regulation of epithelial cell proliferation GO:0050678 141 0.289
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.283
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.281
positive regulation of response to wounding GO:1903036 66 0.276
Mouse
positive regulation of cell migration GO:0030335 109 0.271
Human Mouse
neuronal action potential GO:0019228 54 0.270
activation of immune response GO:0002253 138 0.267
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.265
Mouse
ensheathment of neurons GO:0007272 76 0.264
Mouse
regulation of ion homeostasis GO:2000021 64 0.264
Human Mouse
positive regulation of thymocyte migration GO:2000412 2 0.264
axon ensheathment GO:0008366 76 0.259
Mouse
regulation of rho gtpase activity GO:0032319 58 0.257
regulation of defense response GO:0031347 233 0.255
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.251
Human Mouse
positive regulation of inflammatory response GO:0050729 47 0.251
Mouse
regulation of rho protein signal transduction GO:0035023 71 0.249
cell cell recognition GO:0009988 44 0.245
Mouse
immune effector process GO:0002252 321 0.244
Mouse
angiogenesis GO:0001525 201 0.243
Mouse
cellular metal ion homeostasis GO:0006875 151 0.239
Human Mouse
regulation of b cell mediated immunity GO:0002712 37 0.237
neutrophil chemotaxis GO:0030593 36 0.236
Mouse
monocyte chemotaxis GO:0002548 5 0.236
Human Mouse
t cell differentiation GO:0030217 174 0.234
Mouse
regulation of inflammatory response GO:0050727 147 0.232
Mouse
cellular response to lipid GO:0071396 145 0.232
Human
regulation of b cell chemotaxis GO:2000537 2 0.226
cation transport GO:0006812 399 0.226
Human Mouse
detection of yeast GO:0001879 2 0.225
positive regulation of t cell activation GO:0050870 101 0.225
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.224
regulation of tumor necrosis factor production GO:0032680 49 0.224
Mouse
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.224
negative regulation of leukocyte degranulation GO:0043301 7 0.224
Mouse
interleukin 12 production GO:0032615 32 0.223
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.223
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.221
cell chemotaxis GO:0060326 81 0.219
Human Mouse
regulation of leukocyte proliferation GO:0070663 121 0.217
Mouse
regulation of cell migration GO:0030334 219 0.215
Human Mouse
erk1 and erk2 cascade GO:0070371 77 0.214
cytosolic calcium ion transport GO:0060401 48 0.211
Human Mouse
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.211
Mouse
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.208
regulation of innate immune response GO:0045088 91 0.208
Mouse
divalent inorganic cation transport GO:0072511 178 0.207
Human Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.206
Mouse
adaptive immune response GO:0002250 155 0.204
Mouse
homeostasis of number of cells GO:0048872 210 0.204
interleukin 2 production GO:0032623 33 0.203
Mouse
cell recognition GO:0008037 83 0.203
Mouse
blood vessel morphogenesis GO:0048514 285 0.203
Mouse
regulation of mapk cascade GO:0043408 248 0.202
regulation of chemotaxis GO:0050920 53 0.202
Human Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.201
Mouse
interferon gamma production GO:0032609 67 0.197
Mouse
positive regulation of glycoprotein biosynthetic process GO:0010560 6 0.197
Mouse
cytokine metabolic process GO:0042107 71 0.197
Mouse
ras protein signal transduction GO:0007265 77 0.196
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.195
Mouse
regulation of phagocytosis GO:0050764 33 0.195
myotube differentiation GO:0014902 105 0.194
transmission of nerve impulse GO:0019226 76 0.193
negative thymic t cell selection GO:0045060 12 0.193
Mouse
positive regulation of tumor necrosis factor production GO:0032760 30 0.193
Mouse
response to interferon gamma GO:0034341 34 0.193
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.191
Mouse
membrane organization GO:0061024 245 0.190
Mouse
positive regulation of interleukin 12 production GO:0032735 21 0.190
Mouse
epithelial tube morphogenesis GO:0060562 303 0.190
Mouse
regulation of cytokine production GO:0001817 266 0.190
Mouse
negative regulation of immune system process GO:0002683 209 0.189
Mouse
t cell activation involved in immune response GO:0002286 43 0.189
immunoglobulin production in mucosal tissue GO:0002426 3 0.188
response to molecule of fungal origin GO:0002238 4 0.188
regulation of t helper 1 type immune response GO:0002825 17 0.186
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.186
Mouse
second messenger mediated signaling GO:0019932 73 0.185
Human
t cell receptor signaling pathway GO:0050852 46 0.182
Mouse
negative regulation of blood vessel morphogenesis GO:2000181 25 0.179
Mouse
hypersensitivity GO:0002524 10 0.179
Mouse
neuron migration GO:0001764 122 0.178
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.178
Mouse
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.177
positive regulation of alpha beta t cell activation GO:0046635 39 0.176
Mouse
tumor necrosis factor production GO:0032640 50 0.174
Mouse
leukocyte mediated immunity GO:0002443 174 0.174
Mouse
oligodendrocyte differentiation GO:0048709 53 0.172
Mouse
positive regulation of granulocyte chemotaxis GO:0071624 12 0.169
Mouse
metal ion homeostasis GO:0055065 189 0.169
Human Mouse
multicellular organismal homeostasis GO:0048871 164 0.169
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.168
regulation of interleukin 1 beta secretion GO:0050706 15 0.166
Mouse
negative regulation of eosinophil degranulation GO:0043310 1 0.165
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.163
Mouse
positive regulation of chemotaxis GO:0050921 38 0.163
Human Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.162
exocytosis GO:0006887 121 0.162
Mouse
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.161
Mouse
phagocytosis GO:0006909 66 0.159
regulated secretory pathway GO:0045055 32 0.158
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.158
organ or tissue specific immune response GO:0002251 13 0.157
inflammatory response GO:0006954 244 0.157
Mouse
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.155
immunoglobulin mediated immune response GO:0016064 69 0.155
positive regulation of interferon gamma production GO:0032729 39 0.154
Mouse
myeloid leukocyte migration GO:0097529 57 0.153
Human Mouse
interleukin 1 production GO:0032612 31 0.152
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.151
negative regulation of vasculature development GO:1901343 26 0.150
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.149
cellular response to molecule of bacterial origin GO:0071219 83 0.146
Human
regulation of alpha beta t cell proliferation GO:0046640 18 0.145
Mouse
negative regulation of immune effector process GO:0002698 55 0.145
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.144
cellular nitrogen compound catabolic process GO:0044270 280 0.144
cellular homeostasis GO:0019725 240 0.143
Human Mouse
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.142
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.142
positive regulation of hypersensitivity GO:0002885 7 0.141
Mouse
regulation of angiogenesis GO:0045765 81 0.137
Mouse
regulation of ion transport GO:0043269 215 0.136
cellular response to organonitrogen compound GO:0071417 145 0.136
cellular extravasation GO:0045123 17 0.136
Mouse
regulation of eosinophil migration GO:2000416 2 0.135
positive regulation of mapk cascade GO:0043410 170 0.134
detection of biotic stimulus GO:0009595 10 0.134
nucleotide catabolic process GO:0009166 217 0.133
regulation of protein localization GO:0032880 231 0.132
Mouse
regulation of cytokine production involved in immune response GO:0002718 26 0.131
regulation of cell motility GO:2000145 236 0.130
Human Mouse
positive regulation of cytokine secretion GO:0050715 41 0.129
positive regulation of leukocyte differentiation GO:1902107 86 0.128
positive regulation of lymphocyte proliferation GO:0050671 70 0.127
Mouse
detection of other organism GO:0098543 8 0.126
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.126
Mouse
t cell proliferation GO:0042098 120 0.126
Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.126
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.125
Mouse
regulation of oligodendrocyte differentiation GO:0048713 23 0.125
Mouse
positive regulation of b cell chemotaxis GO:2000538 2 0.124
t cell differentiation in thymus GO:0033077 77 0.124
Mouse
t helper 1 cell differentiation GO:0045063 13 0.124
small gtpase mediated signal transduction GO:0007264 97 0.124
interleukin 1 beta production GO:0032611 30 0.123
Mouse
regulation of gliogenesis GO:0014013 50 0.123
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.122
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.121
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.121
multicellular organismal iron ion homeostasis GO:0060586 8 0.120
regulation of nucleoside metabolic process GO:0009118 130 0.120
positive regulation of cell development GO:0010720 237 0.120
Mouse
regulation of t helper 1 cell cytokine production GO:2000554 1 0.120
negative regulation of innate immune response GO:0045824 17 0.120
Mouse
epithelial cell proliferation GO:0050673 174 0.119
Mouse
modification of morphology or physiology of other organism GO:0035821 18 0.119
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.119
tumor necrosis factor biosynthetic process GO:0042533 10 0.117
Mouse
lymphocyte migration GO:0072676 26 0.117
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.117
chemotaxis GO:0006935 247 0.116
Human Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.116
positive regulation of acute inflammatory response GO:0002675 16 0.115
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.115
t helper 17 cell chemotaxis GO:0035705 1 0.114
Mouse
defense response to virus GO:0051607 68 0.114
type 2 immune response GO:0042092 23 0.113
Mouse
positive regulation of cytokine production involved in immune response GO:0002720 19 0.112
negative regulation of t cell activation GO:0050868 65 0.111
b cell mediated immunity GO:0019724 71 0.110
macrophage activation involved in immune response GO:0002281 7 0.110
Mouse
response to acid chemical GO:0001101 111 0.110
regulation of ossification GO:0030278 112 0.109
antigen receptor mediated signaling pathway GO:0050851 64 0.109
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.109
regulation of glial cell differentiation GO:0045685 41 0.108
Mouse
regulation of map kinase activity GO:0043405 120 0.108
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.108
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.107
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.107
inflammatory response to wounding GO:0090594 4 0.107
myelination GO:0042552 74 0.106
Mouse
purine nucleoside catabolic process GO:0006152 205 0.106
reactive nitrogen species metabolic process GO:2001057 0 0.106
cellular ion homeostasis GO:0006873 165 0.106
Human Mouse
myeloid cell homeostasis GO:0002262 114 0.105
guanosine containing compound catabolic process GO:1901069 144 0.104
regulation of exocytosis GO:0017157 61 0.103
Mouse
cell killing GO:0001906 67 0.102
t helper 2 cell cytokine production GO:0035745 4 0.102
positive regulation of antigen processing and presentation GO:0002579 10 0.102
Mouse
t helper 1 cell cytokine production GO:0035744 1 0.101
endocytosis GO:0006897 168 0.101
regulation of acute inflammatory response GO:0002673 27 0.100
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.100
Human Mouse
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.100
Mouse
myeloid cell activation involved in immune response GO:0002275 34 0.099
Mouse
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.098
neuron projection guidance GO:0097485 141 0.098
Mouse
cytoplasmic transport GO:0016482 234 0.098
Human Mouse
guanosine containing compound metabolic process GO:1901068 144 0.095
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.094
t cell selection GO:0045058 34 0.094
Mouse
acute inflammatory response GO:0002526 41 0.094
Mouse
negative regulation of t cell proliferation GO:0042130 38 0.094
eosinophil migration GO:0072677 3 0.094
sensory perception of pain GO:0019233 47 0.094
Mouse
positive regulation of behavior GO:0048520 40 0.093
Human Mouse
negative regulation of cytokine production GO:0001818 84 0.093
plasma membrane organization GO:0007009 90 0.093
Mouse
negative regulation of angiogenesis GO:0016525 25 0.092
Mouse
motor neuron axon guidance GO:0008045 26 0.092
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.092
regulation of secretion GO:0051046 274 0.091
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.091
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.091
glycosyl compound catabolic process GO:1901658 206 0.090
chemokine production GO:0032602 34 0.089
negative regulation of homeostatic process GO:0032845 71 0.089
Human Mouse
regulation of establishment of protein localization GO:0070201 181 0.089
Mouse
regulation of b cell activation GO:0050864 81 0.087
branching morphogenesis of an epithelial tube GO:0048754 159 0.087
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.087
nucleoside metabolic process GO:0009116 246 0.086
cellular ketone metabolic process GO:0042180 84 0.086
positive regulation of eosinophil migration GO:2000418 2 0.086
defense response to gram positive bacterium GO:0050830 50 0.086
regulation of granulocyte chemotaxis GO:0071622 17 0.085
Mouse
natural killer cell chemotaxis GO:0035747 1 0.085
positive regulation of lymphocyte migration GO:2000403 11 0.085
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.084
regulation of system process GO:0044057 200 0.084
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.083
Mouse
immunological synapse formation GO:0001771 7 0.082
Mouse
cell type specific apoptotic process GO:0097285 268 0.082
cell adhesion GO:0007155 329 0.082
regulation of myeloid cell differentiation GO:0045637 96 0.081
nitric oxide biosynthetic process GO:0006809 25 0.081
vascular endothelial growth factor production GO:0010573 13 0.081
Mouse
positive regulation of t cell chemotaxis GO:0010820 5 0.080
Mouse
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.080
Mouse
regulation of cellular response to stress GO:0080135 159 0.080
regulation of t helper 2 cell cytokine production GO:2000551 3 0.080
sensory perception GO:0007600 245 0.079
Mouse
jnk cascade GO:0007254 72 0.079
positive regulation of interleukin 2 production GO:0032743 19 0.079
Mouse
purine nucleoside metabolic process GO:0042278 241 0.079
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.078
response to interleukin 4 GO:0070670 23 0.078
endomembrane system organization GO:0010256 147 0.078
Mouse
ribose phosphate metabolic process GO:0019693 291 0.077
aromatic compound catabolic process GO:0019439 286 0.077
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.076
Human Mouse
regulation of osteoclast differentiation GO:0045670 36 0.075
cellular response to interleukin 4 GO:0071353 21 0.075
negative regulation of adaptive immune response GO:0002820 25 0.075
alpha beta t cell activation GO:0046631 91 0.075
Mouse
cellular response to interferon gamma GO:0071346 25 0.074
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.074
Mouse
multicellular organismal signaling GO:0035637 91 0.073
positive regulation of neuron apoptotic process GO:0043525 25 0.073
regulation of type 2 immune response GO:0002828 18 0.072
Mouse
regulation of neutrophil migration GO:1902622 14 0.072
Mouse
cellular response to biotic stimulus GO:0071216 92 0.071
Human
signal transduction in absence of ligand GO:0038034 55 0.071
Mouse
ossification GO:0001503 216 0.071
regulation of purine nucleotide catabolic process GO:0033121 122 0.071
negative regulation of protein metabolic process GO:0051248 282 0.071
pattern recognition receptor signaling pathway GO:0002221 47 0.070
organophosphate catabolic process GO:0046434 232 0.070
purine ribonucleotide catabolic process GO:0009154 208 0.070
regulation of leukocyte degranulation GO:0043300 20 0.070
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.069
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.069
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.069
positive regulation of nervous system development GO:0051962 221 0.068
Mouse
response to alcohol GO:0097305 48 0.068
Human
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.068
t cell differentiation involved in immune response GO:0002292 30 0.068
purine containing compound metabolic process GO:0072521 311 0.067
positive regulation of immunoglobulin production GO:0002639 28 0.067
inflammatory response to antigenic stimulus GO:0002437 30 0.067
Mouse
ribonucleotide metabolic process GO:0009259 291 0.065
regulation of striated muscle cell differentiation GO:0051153 81 0.065
extrinsic apoptotic signaling pathway GO:0097191 126 0.065
Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.065
regulation of humoral immune response GO:0002920 22 0.064
Mouse
pallium development GO:0021543 120 0.064
Mouse
negative t cell selection GO:0043383 13 0.063
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.063
regulation of interleukin 2 production GO:0032663 28 0.063
Mouse
t helper 1 type immune response GO:0042088 25 0.063
Mouse
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.063
regulation of cellular ketone metabolic process GO:0010565 66 0.062
positive regulation of protein modification process GO:0031401 299 0.062
leukocyte chemotaxis GO:0030595 69 0.062
Human Mouse
blood circulation GO:0008015 195 0.062
stress activated mapk cascade GO:0051403 80 0.061
negative regulation of cell activation GO:0050866 111 0.061
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.061
cellular amine metabolic process GO:0044106 44 0.060
neuron death GO:0070997 154 0.060
b cell activation involved in immune response GO:0002312 50 0.060
nucleoside phosphate catabolic process GO:1901292 222 0.060
amine metabolic process GO:0009308 45 0.059
leukocyte migration GO:0050900 124 0.059
Human Mouse
apoptotic signaling pathway GO:0097190 306 0.059
Mouse
regulation of protein transport GO:0051223 163 0.059
Mouse
purine nucleotide catabolic process GO:0006195 211 0.059
positive regulation of t helper 1 type immune response GO:0002827 12 0.059
Mouse
leukocyte differentiation GO:0002521 342 0.059
Mouse
response to organonitrogen compound GO:0010243 246 0.059
regulation of neutrophil chemotaxis GO:0090022 14 0.058
Mouse
kidney development GO:0001822 213 0.058
t cell activation GO:0042110 289 0.058
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.058
dendritic cell differentiation GO:0097028 26 0.057
Mouse
positive regulation of calcium ion transport GO:0051928 27 0.057
positive regulation of t cell proliferation GO:0042102 52 0.057
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.057
organonitrogen compound catabolic process GO:1901565 264 0.056
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.056
regulation of ras gtpase activity GO:0032318 88 0.056
calcium mediated signaling GO:0019722 46 0.055
Human
regulation of endothelial cell proliferation GO:0001936 23 0.055
Mouse
anion transport GO:0006820 177 0.055
regulation of t helper 1 cell differentiation GO:0045625 7 0.054
response to host immune response GO:0052572 3 0.054
positive regulation of interleukin 1 beta production GO:0032731 16 0.054
regulation of neuron death GO:1901214 134 0.054
forebrain development GO:0030900 302 0.054
Mouse
antigen processing and presentation GO:0019882 47 0.053
Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.053
nucleoside catabolic process GO:0009164 206 0.053
positive regulation of map kinase activity GO:0043406 84 0.053
regulation of protein kinase activity GO:0045859 232 0.053
t cell migration GO:0072678 19 0.053
Mouse
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.053
regulation of transferase activity GO:0051338 263 0.052
b cell activation GO:0042113 161 0.052
positive regulation of apoptotic cell clearance GO:2000427 3 0.052
interleukin 1 beta secretion GO:0050702 16 0.052
Mouse
regulation of homeostatic process GO:0032844 182 0.051
Human Mouse
dna metabolic process GO:0006259 303 0.051
cytokine secretion GO:0050663 72 0.051
Mouse
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.050
cerebral cortex cell migration GO:0021795 44 0.050
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 40 0.050
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.050
gtp metabolic process GO:0046039 144 0.050
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.049
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.049
regulation of cell adhesion GO:0030155 154 0.049
regulation of response to wounding GO:1903034 189 0.049
Mouse
cellular response to interferon beta GO:0035458 21 0.049
regulation of nucleotide metabolic process GO:0006140 169 0.049
nucleotide metabolic process GO:0009117 332 0.049
positive regulation of protein secretion GO:0050714 52 0.048
reactive oxygen species metabolic process GO:0072593 84 0.048
cellular amino acid metabolic process GO:0006520 103 0.047
defense response to bacterium GO:0042742 119 0.047
axonogenesis GO:0007409 274 0.047
Mouse
regulation of jnk cascade GO:0046328 62 0.047
purine containing compound catabolic process GO:0072523 213 0.047
erythrocyte differentiation GO:0030218 88 0.046
gtp catabolic process GO:0006184 143 0.046
bmp signaling pathway GO:0030509 93 0.046
positive regulation of homeostatic process GO:0032846 64 0.046
iron ion homeostasis GO:0055072 36 0.045
protein kinase b signaling GO:0043491 74 0.045

Ccr5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org