|
|
natural killer cell inhibitory signaling pathway
|
GO:0002769 |
2 |
0.998
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.997
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.996
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.995
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.995
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.994
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.992
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.992
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.987
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.987
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.986
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.985
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.975
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.970
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.967
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.964
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.964
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.960
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.958
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.957
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.957
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.953
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.952
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.950
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.948
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.947
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.947
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.945
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.945
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.943
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.942
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.941
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.937
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.931
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.930
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.930
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.929
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.929
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.919
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.919
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.909
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.908
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.908
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.904
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.901
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.901
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.901
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.898
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.898
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.895
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.889
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.888
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.879
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.875
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.874
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.874
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.874
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.870
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.863
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.859
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.855
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.854
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.850
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.848
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.847
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.845
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.844
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.840
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.831
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.830
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.827
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.822
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.822
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.821
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.819
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.812
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.811
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.807
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.807
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.800
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.790
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.789
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.789
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.782
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.781
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.779
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.778
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.764
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.762
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.758
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.750
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.749
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.747
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.746
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.745
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.741
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.724
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.720
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.719
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.716
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.712
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.706
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.704
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.700
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.699
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.695
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.691
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.688
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.686
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.680
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.667
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.666
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.659
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.654
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.646
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.635
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.635
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.627
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.622
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.618
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.614
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.609
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.607
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.605
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.598
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.596
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.594
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.575
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.573
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.572
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.550
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.548
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.545
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.540
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.529
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.524
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.519
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.518
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.516
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.514
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.504
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.502
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.499
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.494
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.489
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.486
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.485
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.483
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.482
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.482
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.482
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.481
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.478
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.478
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.477
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.471
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.468
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.466
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.460
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.453
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.444
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.443
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.441
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.440
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.436
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.433
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.421
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.421
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.420
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.416
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.410
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.405
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.402
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.401
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.399
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.397
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.393
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.391
|
|
|
|
regulation of vesicle fusion
|
GO:0031338 |
6 |
0.377
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.376
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.374
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.373
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.371
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.369
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.366
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.366
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.365
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.358
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.353
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.348
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.346
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.344
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.333
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.330
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.328
|
|
|
|
positive regulation of protein targeting to membrane
|
GO:0090314 |
7 |
0.327
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.326
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.322
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.320
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.314
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.312
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.308
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.307
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.306
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.305
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.297
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.293
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.292
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.290
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.289
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.284
|
|
|
|
activation of membrane attack complex
|
GO:0001905 |
4 |
0.280
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.280
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.279
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.278
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.278
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.275
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.273
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.270
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.267
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.266
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.266
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.265
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.264
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.264
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.261
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.257
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.257
|
|
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.252
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.246
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.246
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.245
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.244
|
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.244
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.242
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.241
|
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.240
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.240
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.238
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.237
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.237
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.237
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.236
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.234
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.233
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.232
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.231
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.231
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.230
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.229
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.228
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.227
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.226
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.224
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.224
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.223
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.221
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.218
|
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.214
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.208
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.208
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.208
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.208
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.208
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.206
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.205
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.205
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
8 |
0.205
|
|
|
|
regulation of ral gtpase activity
|
GO:0032315 |
4 |
0.204
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.202
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.202
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.201
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.201
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.200
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.195
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.194
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.194
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.192
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.191
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.191
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.189
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.188
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.184
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.184
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.181
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.180
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.178
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.178
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.177
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.176
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.174
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.174
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.173
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.172
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.171
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.171
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.171
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.171
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.170
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.169
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.168
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.167
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.167
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.165
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.162
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.162
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.161
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.160
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.160
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.158
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.158
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.157
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.156
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.155
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.155
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.154
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
6 |
0.153
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.153
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.153
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.152
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.151
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.149
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.149
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.149
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.149
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.149
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.149
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.148
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.148
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.147
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.145
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.145
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.142
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.140
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.139
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.139
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.139
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.139
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.139
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.138
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.137
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.137
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.137
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.135
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.135
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.135
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.135
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.135
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.135
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.132
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.131
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.130
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.129
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.127
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.127
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.127
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.126
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.122
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.122
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.120
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.120
|
|
|
|
positive regulation of interleukin 5 secretion
|
GO:2000664 |
1 |
0.120
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.120
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.119
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.119
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.119
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.119
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.119
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.117
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.116
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.115
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.115
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.114
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.114
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.113
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.112
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.112
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.111
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.110
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.110
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.109
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.109
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.108
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.108
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.108
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.108
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.107
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.107
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.107
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.107
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.107
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.106
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.106
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.106
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.105
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
22 |
0.104
|
|
|
|
positive regulation of interleukin 13 production
|
GO:0032736 |
4 |
0.103
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.103
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.103
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.103
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.102
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.101
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.101
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.101
|
|
|
|
spongiotrophoblast layer development
|
GO:0060712 |
15 |
0.101
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.100
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.100
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.100
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.100
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.099
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.099
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.098
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.098
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.098
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.098
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.098
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.098
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.096
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.096
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.096
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.095
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.095
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.094
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.093
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.093
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.092
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.091
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.091
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.090
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.090
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.090
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.089
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.089
|
|
|
|
positive regulation of interleukin 13 secretion
|
GO:2000667 |
1 |
0.089
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.089
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.088
|
|
|
|
oncostatin m mediated signaling pathway
|
GO:0038165 |
1 |
0.087
|
|
|
|
positive regulation of interleukin 10 secretion
|
GO:2001181 |
1 |
0.087
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.085
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.085
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.085
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.084
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.084
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.084
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.083
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.083
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.082
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.081
|
|
|
|
regulation of tolerance induction dependent upon immune response
|
GO:0002652 |
1 |
0.081
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.080
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.080
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.079
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.079
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.079
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.079
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.079
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.079
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.078
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.078
|
|
|
|
maintenance of apical basal cell polarity
|
GO:0035090 |
3 |
0.077
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.077
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.077
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.076
|
|
|
|
positive regulation of t helper 2 cell activation
|
GO:2000570 |
2 |
0.076
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.076
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.075
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.075
|
|
|
|
modulation by virus of host process
|
GO:0019054 |
2 |
0.075
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.074
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.073
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.073
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.073
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.073
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.072
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.072
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.072
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.072
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.072
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.071
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.071
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.071
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.071
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.071
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.070
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.070
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.069
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.069
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.069
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.068
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.068
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.068
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.068
|
|
