|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.867
|
|
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.823
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.811
|
Mouse |
|
|
positive regulation of toll like receptor 9 signaling pathway
|
GO:0034165 |
2 |
0.744
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.739
|
Mouse |
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.692
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.635
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.623
|
|
|
|
toll like receptor 9 signaling pathway
|
GO:0034162 |
6 |
0.576
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.554
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.547
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.526
|
|
|
|
serotonin secretion by mast cell
|
GO:0002552 |
1 |
0.497
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.460
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.451
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.419
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.417
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.405
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.396
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
2 |
0.389
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.376
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.375
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.373
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.357
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.349
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.348
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.341
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.337
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.337
|
Mouse |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.329
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.324
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.316
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.310
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.296
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.294
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.290
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.278
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.269
|
|
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.267
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.262
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.260
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.243
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.238
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.237
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.236
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.233
|
|
|
|
negative regulation of mast cell degranulation
|
GO:0043305 |
4 |
0.231
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.226
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.225
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.221
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.221
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.216
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.206
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.198
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.191
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.190
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.188
|
|
|
|
positive regulation by symbiont of host defense response
|
GO:0052509 |
1 |
0.187
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.187
|
|
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.182
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.181
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.181
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.179
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.171
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.165
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.164
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.159
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.159
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.158
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.158
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.154
|
|
|
|
detection of other organism
|
GO:0098543 |
8 |
0.154
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.153
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.149
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.148
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.146
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.145
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.145
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.145
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.138
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.136
|
|
|
|
detection of bacterium
|
GO:0016045 |
7 |
0.135
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.134
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.132
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.132
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.131
|
|
|
|
detection of biotic stimulus
|
GO:0009595 |
10 |
0.130
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.129
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.126
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.124
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.123
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.123
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
9 |
0.121
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.119
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.119
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.117
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.116
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.115
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.115
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.115
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.115
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.113
|
|
|
|
detection of peptidoglycan
|
GO:0032499 |
1 |
0.113
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.112
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.112
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.110
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.109
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.108
|
|
|
|
response to host
|
GO:0075136 |
3 |
0.106
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.106
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.102
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.101
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.101
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.101
|
|
|
|
regulation of interleukin 18 production
|
GO:0032661 |
3 |
0.100
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.098
|
Mouse |
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.097
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.097
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.096
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.094
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.093
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.093
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.093
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.091
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.090
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.089
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.089
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.088
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.085
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.084
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.083
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.083
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.082
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.081
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.081
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.081
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.081
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.080
|
|
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.078
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.077
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.077
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.076
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.076
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.075
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.073
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.073
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.073
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.073
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.073
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.073
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.072
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.072
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.071
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.071
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.070
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.070
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.068
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.068
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.068
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.068
|
|
|
|
response to peptidoglycan
|
GO:0032494 |
9 |
0.068
|
|
|
|
response to lipoteichoic acid
|
GO:0070391 |
6 |
0.067
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.067
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.067
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.066
|
|
|
|
negative regulation of mast cell activation involved in immune response
|
GO:0033007 |
5 |
0.066
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.065
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.064
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.064
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.064
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.063
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.063
|
|
|
|
negative regulation of mast cell activation
|
GO:0033004 |
6 |
0.062
|
|
|
|
positive regulation of interferon alpha biosynthetic process
|
GO:0045356 |
1 |
0.062
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.061
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.061
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.061
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.061
|
|
|
|
response to host immune response
|
GO:0052572 |
3 |
0.060
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.060
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.059
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.058
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.058
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.058
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.057
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.057
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.057
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.057
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.057
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.057
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.056
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.055
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.055
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.055
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.054
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.054
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.054
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.054
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.053
|
|
|
|
g protein coupled purinergic nucleotide receptor signaling pathway
|
GO:0035589 |
1 |
0.053
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.053
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.052
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.051
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.051
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.051
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.051
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.051
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.051
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.050
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.050
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.050
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.049
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.049
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.049
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.049
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.049
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.048
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.048
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.048
|
|
|
|
response to defense related nitric oxide production by other organism involved in symbiotic interaction
|
GO:0052551 |
2 |
0.048
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.048
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.048
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.048
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.048
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.047
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.047
|
|
|
|
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070428 |
3 |
0.047
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.047
|
|
|
|
induction by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052558 |
1 |
0.046
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
27 |
0.046
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.046
|
|
|
|
response to bacterial lipoprotein
|
GO:0032493 |
4 |
0.046
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.046
|
|
|
|
transepithelial chloride transport
|
GO:0030321 |
4 |
0.046
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.045
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.045
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.045
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.045
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.045
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.045
|
|
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
4 |
0.045
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.044
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.044
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.044
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.044
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.043
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.043
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.043
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.043
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.043
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.042
|
|
|
|
toxin catabolic process
|
GO:0009407 |
1 |
0.042
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.042
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.042
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.042
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.042
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.042
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.042
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.042
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.042
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.042
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.041
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.041
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.041
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.041
|
|
|
|
response to host defenses
|
GO:0052200 |
3 |
0.041
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.040
|
|
|
|
purinergic receptor signaling pathway
|
GO:0035587 |
7 |
0.040
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
28 |
0.040
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.040
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.040
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.040
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.040
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.040
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.040
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.039
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.039
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.039
|
|
|
|
modulation by symbiont of host immune response
|
GO:0052553 |
1 |
0.039
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.039
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.039
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.039
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.039
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.039
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.038
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.038
|
|
|
|
positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070434 |
2 |
0.038
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.038
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.038
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.038
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.038
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.038
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.038
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.038
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.037
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.037
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.037
|
|
|
|
cellular response to lipoteichoic acid
|
GO:0071223 |
6 |
0.037
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.037
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.037
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.037
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.037
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.036
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.036
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.036
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.036
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.036
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.036
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.036
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.036
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.036
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.036
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.035
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.035
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.035
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.035
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.035
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.035
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.035
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.035
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.034
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.034
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.034
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.034
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.034
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.034
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.034
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.034
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.033
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.033
|
|
|
|
intestinal epithelial structure maintenance
|
GO:0060729 |
4 |
0.033
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.033
|
|
|
|
histamine transport
|
GO:0051608 |
2 |
0.033
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
6 |
0.033
|
|
|
|
negative regulation of myeloid leukocyte mediated immunity
|
GO:0002887 |
7 |
0.033
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.033
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.033
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.032
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.032
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.032
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.032
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.032
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.032
|
|
|
|
serotonin transport
|
GO:0006837 |
11 |
0.032
|
|
|
|
modulation by organism of defense response of other organism involved in symbiotic interaction
|
GO:0052255 |
1 |
0.031
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.031
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.031
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.031
|
|
|
|
response to immune response of other organism involved in symbiotic interaction
|
GO:0052564 |
3 |
0.031
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.031
|
|
|
|
response to defense related host nitric oxide production
|
GO:0052565 |
2 |
0.031
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.031
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.031
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.031
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.031
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.031
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.031
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.031
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.031
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.031
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
3 |
0.031
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.031
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.030
|
|
|
|
transcytosis
|
GO:0045056 |
5 |
0.030
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.030
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.030
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.030
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.030
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.030
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.030
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.030
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.030
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.030
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.030
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.030
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.029
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.029
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.029
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.029
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.029
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.029
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.029
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.029
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.029
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.029
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.029
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.029
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.029
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.029
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.028
|
Mouse |
|
|
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070430 |
1 |
0.028
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.028
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.028
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.028
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.028
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.028
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.027
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.027
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.027
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.027
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.027
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.027
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.027
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.027
|
|
|
|
cellular response to bacterial lipopeptide
|
GO:0071221 |
3 |
0.027
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.027
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.027
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.026
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.026
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.026
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.026
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.026
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.026
|
|
|
|
positive regulation by symbiont of host immune response
|
GO:0052556 |
1 |
0.026
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.026
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.026
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.026
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
4 |
0.026
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.026
|
|
|
|
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction
|
GO:0052345 |
1 |
0.026
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.026
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.025
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.025
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.025
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.025
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.025
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.025
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.025
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.025
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.025
|
|
|
|
modulation by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052552 |
1 |
0.025
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
30 |
0.025
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.025
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.025
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.025
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.024
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.024
|
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
3 |
0.024
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.024
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.024
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.024
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.024
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.024
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.024
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.024
|
|
|
|
positive regulation of platelet activation
|
GO:0010572 |
5 |
0.024
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.024
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.024
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.024
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.024
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.024
|
|
|
|
positive regulation of chemokine secretion
|
GO:0090197 |
4 |
0.023
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.023
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.023
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.023
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.023
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.023
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.023
|
|
|
|
positive regulation of coagulation
|
GO:0050820 |
13 |
0.023
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.023
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.023
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.023
|
|
|
|
detection of lipoteichoic acid
|
GO:0070392 |
1 |
0.023
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.023
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.023
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.023
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.023
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.023
|
|
|
|
detection of lipopolysaccharide
|
GO:0032497 |
1 |
0.023
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.023
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.023
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.023
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.023
|
|
|
|
negative regulation of leukocyte degranulation
|
GO:0043301 |
7 |
0.022
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.022
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.022
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.022
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.022
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.022
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.022
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.022
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.022
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.022
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.022
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.022
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.022
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.022
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.022
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.022
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.022
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.021
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.021
|
|
