Mus musculus

213 known processes

Cd44

CD44 antigen

(Aliases: Pgp-1,Ly-24,AU023126,HERMES,AW146109,AW121933)

Cd44 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
activation of mapk activity involved in innate immune response GO:0035419 2 1.000
nucleotide binding oligomerization domain containing signaling pathway GO:0070423 6 0.999
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.998
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.998
leukocyte apoptotic process GO:0071887 71 0.997
t cell extravasation GO:0072683 4 0.997
cellular response to peptidoglycan GO:0071224 4 0.997
regulation of t cell extravasation GO:2000407 3 0.996
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.995
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.995
cytokine mediated signaling pathway GO:0019221 115 0.994
i kappab kinase nf kappab signaling GO:0007249 85 0.994
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.993
negative regulation of intracellular signal transduction GO:1902532 167 0.993
negative regulation of macrophage apoptotic process GO:2000110 3 0.992
immune complex clearance GO:0002434 2 0.990
chemotaxis GO:0006935 247 0.990
granulocyte chemotaxis GO:0071621 39 0.990
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.990
chemokine production GO:0032602 34 0.989
positive regulation of neuron projection development GO:0010976 79 0.989
granulocyte migration GO:0097530 43 0.988
antibacterial peptide production GO:0002778 2 0.987
eosinophil degranulation GO:0043308 1 0.987
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.986
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.986
positive regulation of b cell mediated immunity GO:0002714 26 0.986
mapk cascade GO:0000165 281 0.984
response to lipopolysaccharide GO:0032496 128 0.983
regulation of acute inflammatory response GO:0002673 27 0.983
regulation of apoptotic signaling pathway GO:2001233 197 0.982
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.982
interleukin 18 mediated signaling pathway GO:0035655 2 0.981
myeloid cell apoptotic process GO:0033028 22 0.980
regulation of response to wounding GO:1903034 189 0.979
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.979
regulation of mapk cascade GO:0043408 248 0.978
cellular response to cytokine stimulus GO:0071345 189 0.978
cellular amine metabolic process GO:0044106 44 0.978
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.978
cellular response to molecule of bacterial origin GO:0071219 83 0.977
response to interleukin 1 GO:0070555 11 0.975
eosinophil activation involved in immune response GO:0002278 1 0.973
positive regulation of programmed cell death GO:0043068 218 0.971
extrinsic apoptotic signaling pathway GO:0097191 126 0.971
positive regulation of protein phosphorylation GO:0001934 242 0.970
regulation of protein kinase activity GO:0045859 232 0.970
regulation of interleukin 1 production GO:0032652 26 0.969
regulation of map kinase activity GO:0043405 120 0.969
positive regulation of mapk cascade GO:0043410 170 0.969
cellular response to interleukin 18 GO:0071351 3 0.968
regulation of neutrophil chemotaxis GO:0090022 14 0.967
negative regulation of nik nf kappab signaling GO:1901223 2 0.967
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.967
regulation of inflammatory response GO:0050727 147 0.966
peptidyl tyrosine phosphorylation GO:0018108 143 0.965
regulation of interleukin 2 production GO:0032663 28 0.963
activation of mapk activity GO:0000187 59 0.962
regulation of dendritic cell chemotaxis GO:2000508 1 0.962
positive regulation of apoptotic signaling pathway GO:2001235 95 0.961
immune response activating signal transduction GO:0002757 116 0.960
immune complex clearance by monocytes and macrophages GO:0002436 2 0.959
nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070431 6 0.957
positive regulation of endopeptidase activity GO:0010950 43 0.957
regulation of cellular amine metabolic process GO:0033238 20 0.956
inflammatory cell apoptotic process GO:0006925 11 0.955
positive regulation of antimicrobial peptide production GO:0002225 1 0.954
adaptive immune response GO:0002250 155 0.954
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.952
positive regulation of cell development GO:0010720 237 0.951
cellular response to biotic stimulus GO:0071216 92 0.948
cellular amino acid metabolic process GO:0006520 103 0.947
positive regulation of immunological synapse formation GO:2000522 1 0.944
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.941
interleukin 6 production GO:0032635 58 0.941
negative regulation of inflammatory response GO:0050728 61 0.938
antibacterial peptide biosynthetic process GO:0002780 2 0.938
defense response to gram positive bacterium GO:0050830 50 0.937
positive regulation of adaptive immune response GO:0002821 61 0.937
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.935
positive regulation of apoptotic process GO:0043065 217 0.935
lymphocyte mediated immunity GO:0002449 139 0.934
positive regulation of map kinase activity GO:0043406 84 0.934
positive regulation of acute inflammatory response GO:0002675 16 0.934
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.933
regulation of antigen processing and presentation GO:0002577 10 0.931
regulation of tumor necrosis factor production GO:0032680 49 0.926
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.926
regulation of cell activation GO:0050865 289 0.925
amine metabolic process GO:0009308 45 0.925
positive regulation of t cell costimulation GO:2000525 2 0.923
stress activated protein kinase signaling cascade GO:0031098 81 0.922
interspecies interaction between organisms GO:0044419 83 0.921
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.920
induction by organism of immune response of other organism involved in symbiotic interaction GO:0052558 1 0.919
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.919
zymogen activation GO:0031638 41 0.918
eosinophil activation GO:0043307 1 0.917
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.914
leukocyte migration GO:0050900 124 0.914
positive regulation of protein modification process GO:0031401 299 0.913
regulation of leukocyte apoptotic process GO:2000106 56 0.912
regulation of cell migration GO:0030334 219 0.907
regulation of cellular amino acid metabolic process GO:0006521 5 0.907
defense response to other organism GO:0098542 197 0.905
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.904
regulation of cellular response to stress GO:0080135 159 0.902
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.902
regulation of interleukin 18 production GO:0032661 3 0.900
t cell activation GO:0042110 289 0.899
leukocyte chemotaxis GO:0030595 69 0.898
interleukin 12 production GO:0032615 32 0.898
regulation of cell projection organization GO:0031344 206 0.895
positive regulation of kinase activity GO:0033674 155 0.893
regulation of cell motility GO:2000145 236 0.892
regulation of monocyte extravasation GO:2000437 2 0.891
organ or tissue specific immune response GO:0002251 13 0.890
microglial cell activation involved in immune response GO:0002282 1 0.889
regulation of growth of symbiont in host GO:0044126 19 0.889
cellular ketone metabolic process GO:0042180 84 0.888
positive regulation of hydrolase activity GO:0051345 148 0.886
positive regulation of cell projection organization GO:0031346 95 0.885
positive regulation of cellular amine metabolic process GO:0033240 5 0.884
regulation of interleukin 6 production GO:0032675 55 0.883
myeloid leukocyte migration GO:0097529 57 0.883
positive regulation of cell death GO:0010942 224 0.882
positive regulation of monocyte chemotaxis GO:0090026 2 0.882
regulation of kinase activity GO:0043549 249 0.877
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.875
negative regulation of phosphorus metabolic process GO:0010563 184 0.873
positive regulation of tumor necrosis factor production GO:0032760 30 0.873
t cell differentiation in thymus GO:0033077 77 0.872
positive regulation of peptidase activity GO:0010952 49 0.872
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.871
regulation of transferase activity GO:0051338 263 0.870
regulation of prostaglandin endoperoxide synthase activity GO:0060584 2 0.867
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.866
response to molecule of bacterial origin GO:0002237 143 0.865
positive regulation of t cell proliferation GO:0042102 52 0.864
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.862
erk1 and erk2 cascade GO:0070371 77 0.861
positive regulation of t cell extravasation GO:2000409 2 0.860
glial cell differentiation GO:0010001 131 0.859
cytokine production GO:0001816 319 0.858
chemokine mediated signaling pathway GO:0070098 17 0.857
antigen processing and presentation GO:0019882 47 0.856
leukocyte mediated immunity GO:0002443 174 0.855
regulation of granulocyte chemotaxis GO:0071622 17 0.853
positive regulation of cell activation GO:0050867 158 0.853
detection of molecule of bacterial origin GO:0032490 2 0.851
macrophage activation GO:0042116 27 0.850
positive regulation of leukocyte differentiation GO:1902107 86 0.848
regulation of defense response to bacterium GO:1900424 3 0.848
response to hypoxia GO:0001666 58 0.848
regulation of neutrophil migration GO:1902622 14 0.848
t helper 1 type immune response GO:0042088 25 0.842
neutrophil migration GO:1990266 37 0.842
morphogenesis of a branching structure GO:0001763 203 0.838
positive regulation of t helper 1 type immune response GO:0002827 12 0.837
regulation of peptidase activity GO:0052547 96 0.834
Human
inflammatory response to antigenic stimulus GO:0002437 30 0.830
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070428 3 0.830
cell chemotaxis GO:0060326 81 0.825
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.825
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.825
immunoglobulin mediated immune response GO:0016064 69 0.823
lymphocyte migration GO:0072676 26 0.820
negative regulation of interferon gamma production GO:0032689 18 0.816
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.814
regulation of innate immune response GO:0045088 91 0.813
negative regulation of cytokine production GO:0001818 84 0.812
regulation of protein serine threonine kinase activity GO:0071900 157 0.811
positive regulation of interleukin 18 production GO:0032741 2 0.811
peptidyl amino acid modification GO:0018193 336 0.811
phospholipid metabolic process GO:0006644 87 0.811
positive regulation of t cell differentiation GO:0045582 52 0.811
regulation of nucleotide binding oligomerization domain containing signaling pathway GO:0070424 3 0.810
regulation of defense response GO:0031347 233 0.809
ras protein signal transduction GO:0007265 77 0.808
positive regulation of nervous system development GO:0051962 221 0.806
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.804
regulation of type 2 immune response GO:0002828 18 0.801
positive regulation of monocyte extravasation GO:2000439 1 0.799
positive regulation of interleukin 6 production GO:0032755 37 0.798
vascular endothelial growth factor production GO:0010573 13 0.797
regulation of chemotaxis GO:0050920 53 0.795
keratinocyte migration GO:0051546 3 0.793
positive regulation of cytokine production GO:0001819 174 0.791
regulation of interleukin 1 secretion GO:0050704 15 0.787
regulation of immunological synapse formation GO:2000520 2 0.786
positive regulation of cell migration GO:0030335 109 0.784
acute inflammatory response GO:0002526 41 0.782
negative regulation of phosphorylation GO:0042326 166 0.780
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.779
regulation of rho gtpase activity GO:0032319 58 0.776
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.774
response to organic cyclic compound GO:0014070 198 0.774
cell cell recognition GO:0009988 44 0.771
t cell differentiation GO:0030217 174 0.770
positive regulation of t cell activation GO:0050870 101 0.770
negative regulation of defense response GO:0031348 77 0.768
regulation of body fluid levels GO:0050878 162 0.762
cell adhesion GO:0007155 329 0.758
response to oxygen levels GO:0070482 62 0.754
helper t cell enhancement of adaptive immune response GO:0035397 1 0.753
negative regulation of apoptotic signaling pathway GO:2001234 104 0.750
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.750
positive regulation of chemokine production GO:0032722 22 0.750
interleukin 18 production GO:0032621 4 0.746
regulation of membrane potential GO:0042391 192 0.745
regulation of cytokine production GO:0001817 266 0.745
membrane organization GO:0061024 245 0.742
negative regulation of vasculature development GO:1901343 26 0.741
positive regulation of chemotaxis GO:0050921 38 0.740
interleukin 11 mediated signaling pathway GO:0038154 2 0.740
regulation of chemokine production GO:0032642 30 0.738
immune response regulating signaling pathway GO:0002764 125 0.730
modulation by symbiont of defense related host nitric oxide production GO:0052163 1 0.728
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.727
pattern recognition receptor signaling pathway GO:0002221 47 0.726
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.724
response to organonitrogen compound GO:0010243 246 0.724
regulation of t cell costimulation GO:2000523 2 0.723
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.717
cellular response to lipopolysaccharide GO:0071222 77 0.716
innate immune response activating signal transduction GO:0002758 50 0.712
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.712
nitric oxide synthase biosynthetic process GO:0051767 7 0.711
response to host immune response GO:0052572 3 0.710
regulation of glial cell differentiation GO:0045685 41 0.705
cellular extravasation GO:0045123 17 0.704
regulation of myeloid cell apoptotic process GO:0033032 19 0.702
regulation of neuron projection development GO:0010975 169 0.698
response to peptidoglycan GO:0032494 9 0.697
myelination GO:0042552 74 0.695
jnk cascade GO:0007254 72 0.695
peptidyl tyrosine modification GO:0018212 145 0.694
myeloid leukocyte activation GO:0002274 83 0.691
cellular lipid metabolic process GO:0044255 323 0.688
positive regulation of phagocytosis GO:0050766 26 0.687
blood vessel morphogenesis GO:0048514 285 0.685
cellular response to organonitrogen compound GO:0071417 145 0.684
regulation of reactive oxygen species metabolic process GO:2000377 40 0.683
interleukin 2 production GO:0032623 33 0.683
positive regulation of neuron differentiation GO:0045666 141 0.682
neutrophil chemotaxis GO:0030593 36 0.681
positive regulation of lymphocyte activation GO:0051251 140 0.676
helper t cell chemotaxis GO:0035704 1 0.675
negative regulation of response to wounding GO:1903035 77 0.672
regulation of interferon gamma production GO:0032649 57 0.666
positive regulation of defense response GO:0031349 124 0.664
positive regulation of glial cell proliferation GO:0060252 4 0.659
regulation of b cell mediated immunity GO:0002712 37 0.659
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.658
angiogenesis GO:0001525 201 0.657
regulation of interleukin 1 beta production GO:0032651 25 0.656
positive regulation of gtpase activity GO:0043547 85 0.647
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.647
regulation of neuron differentiation GO:0045664 281 0.647
activation of cysteine type endopeptidase activity GO:0097202 27 0.641
apoptotic signaling pathway GO:0097190 306 0.641
regulation of wound healing GO:0061041 40 0.639
response to radiation GO:0009314 165 0.638
positive regulation of macrophage chemotaxis GO:0010759 5 0.636
dendritic cell migration GO:0036336 12 0.631
regulation of nucleotide metabolic process GO:0006140 169 0.630
positive regulation of protein kinase activity GO:0045860 144 0.630
modulation by symbiont of host immune response GO:0052553 1 0.630
negative regulation of cellular amine metabolic process GO:0033239 1 0.628
response to low density lipoprotein particle GO:0055098 2 0.627
epithelial cell proliferation GO:0050673 174 0.627
interleukin 12 secretion GO:0072610 3 0.620
calcium ion transport GO:0006816 159 0.615
wound healing GO:0042060 157 0.610
small gtpase mediated signal transduction GO:0007264 97 0.610
induction by symbiont of host immune response GO:0052559 1 0.609
purine ribonucleoside metabolic process GO:0046128 241 0.604
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.602
eosinophil mediated immunity GO:0002447 1 0.596
interleukin 1 secretion GO:0050701 16 0.596
negative regulation of protein modification process GO:0031400 163 0.595
protein kinase b signaling GO:0043491 74 0.592
cellular amide metabolic process GO:0043603 58 0.591
positive regulation of hemostasis GO:1900048 10 0.587
regulation of t cell activation GO:0050863 170 0.587
regulation of cellular catabolic process GO:0031329 242 0.585
negative regulation of homeostatic process GO:0032845 71 0.583
cell type specific apoptotic process GO:0097285 268 0.583
regulation of t helper 1 type immune response GO:0002825 17 0.582
lymphocyte activation involved in immune response GO:0002285 93 0.581
regulation of hematopoietic stem cell migration GO:2000471 1 0.577
positive regulation of response to wounding GO:1903036 66 0.575
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.575
regulation of erk1 and erk2 cascade GO:0070372 71 0.574
rho protein signal transduction GO:0007266 32 0.568
positive regulation of gliogenesis GO:0014015 27 0.566
response to metal ion GO:0010038 47 0.566
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.565
regulation of ras gtpase activity GO:0032318 88 0.565
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.565
regulation of vesicle mediated transport GO:0060627 139 0.563
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway GO:0070430 1 0.563
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.560
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.559
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.558
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.557
actin filament organization GO:0007015 113 0.555
regulation of cellular ketone metabolic process GO:0010565 66 0.555
positive regulation of leukocyte proliferation GO:0070665 73 0.552
lymphocyte differentiation GO:0030098 242 0.548
regulation of cytokine biosynthetic process GO:0042035 59 0.547
negative regulation of phosphate metabolic process GO:0045936 184 0.542
regulation of rho protein signal transduction GO:0035023 71 0.541
regulation of cytokine secretion GO:0050707 61 0.540
positive regulation of immune effector process GO:0002699 107 0.537
axon guidance GO:0007411 141 0.534
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.532
positive regulation of epithelial cell proliferation GO:0050679 68 0.531
antigen receptor mediated signaling pathway GO:0050851 64 0.531
regulation of leukocyte mediated immunity GO:0002703 104 0.528
positive regulation of proteolysis GO:0045862 85 0.528
positive regulation of antigen processing and presentation GO:0002579 10 0.528
reactive oxygen species metabolic process GO:0072593 84 0.525
cellular homeostasis GO:0019725 240 0.523
hematopoietic stem cell migration GO:0035701 1 0.521
guanosine containing compound catabolic process GO:1901069 144 0.521
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.520
neuronal action potential GO:0019228 54 0.519
regulation of purine nucleotide metabolic process GO:1900542 169 0.512
negative regulation of growth GO:0045926 99 0.512
regulation of interleukin 12 production GO:0032655 30 0.512
stress activated mapk cascade GO:0051403 80 0.511
purine containing compound catabolic process GO:0072523 213 0.509
negative regulation of mapk cascade GO:0043409 65 0.508
negative regulation of angiogenesis GO:0016525 25 0.507
regulation of lymphocyte differentiation GO:0045619 107 0.507
signal transduction in absence of ligand GO:0038034 55 0.506
response to defense related host nitric oxide production GO:0052565 2 0.505
positive regulation of cell motility GO:2000147 116 0.503
positive regulation of cellular component biogenesis GO:0044089 94 0.503
t cell receptor signaling pathway GO:0050852 46 0.502
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.502
cd4 positive alpha beta t cell activation GO:0035710 45 0.500
positive regulation of stress activated mapk cascade GO:0032874 48 0.500
regulation of alpha beta t cell proliferation GO:0046640 18 0.500
regulation of jnk cascade GO:0046328 62 0.496
regulation of leukocyte proliferation GO:0070663 121 0.494
regulation of interleukin 1 beta secretion GO:0050706 15 0.493
negative thymic t cell selection GO:0045060 12 0.492
mucosal immune response GO:0002385 13 0.491
transmembrane transport GO:0055085 412 0.490
purine nucleotide metabolic process GO:0006163 302 0.489
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.485
regulation of cytokine production involved in immune response GO:0002718 26 0.483
fertilization GO:0009566 127 0.483
regulation of coagulation GO:0050818 31 0.480
response to decreased oxygen levels GO:0036293 59 0.479
gtp catabolic process GO:0006184 143 0.479
regulation of lymphocyte activation GO:0051249 240 0.479
positive regulation of hypersensitivity GO:0002885 7 0.477
regulation of interferon beta biosynthetic process GO:0045357 4 0.475
regulation of protein transport GO:0051223 163 0.475
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.474
interferon gamma production GO:0032609 67 0.474
cellular response to peptide GO:1901653 92 0.472
positive regulation by symbiont of host immune response GO:0052556 1 0.471
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.468
phagocytosis GO:0006909 66 0.468
organic acid transport GO:0015849 101 0.467
negative regulation of map kinase activity GO:0043407 34 0.467
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.467
leukocyte activation involved in immune response GO:0002366 126 0.464
response to transition metal nanoparticle GO:1990267 11 0.464
positive regulation of inflammatory response GO:0050729 47 0.462
negative regulation of fibrinolysis GO:0051918 1 0.461
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.460
protein processing GO:0016485 163 0.458
Human
cellular metal ion homeostasis GO:0006875 151 0.456
leukocyte differentiation GO:0002521 342 0.456
regulation of cell projection assembly GO:0060491 38 0.454
positive regulation of blood coagulation GO:0030194 10 0.452
platelet activation GO:0030168 40 0.452
negative regulation of protein phosphorylation GO:0001933 126 0.452
ribonucleotide metabolic process GO:0009259 291 0.451
cellular response to oxidative stress GO:0034599 76 0.450
posttranscriptional regulation of gene expression GO:0010608 155 0.450
regulation of actin filament based process GO:0032970 99 0.443
response to tumor necrosis factor GO:0034612 26 0.440
cellular response to lipid GO:0071396 145 0.440
divalent inorganic cation transport GO:0072511 178 0.440
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.437
regulation of nucleoside metabolic process GO:0009118 130 0.435
response to amino acid GO:0043200 37 0.434
alpha beta t cell proliferation GO:0046633 21 0.433
regulation of secretion by cell GO:1903530 249 0.429
modification of morphology or physiology of other organism GO:0035821 18 0.429
positive regulation of antimicrobial humoral response GO:0002760 2 0.429
cellular response to bacterial lipoprotein GO:0071220 3 0.428
tumor necrosis factor production GO:0032640 50 0.428
regulation of cellular component biogenesis GO:0044087 181 0.427
immune effector process GO:0002252 321 0.426
response to alkaloid GO:0043279 34 0.425
antimicrobial peptide production GO:0002775 2 0.421
organonitrogen compound biosynthetic process GO:1901566 192 0.421
chloramphenicol transport GO:0042892 1 0.420
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.419
granulocyte activation GO:0036230 10 0.418
negative regulation of blood vessel morphogenesis GO:2000181 25 0.413
defense response to bacterium GO:0042742 119 0.411
regulation of phagocytosis GO:0050764 33 0.408
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.407
divalent metal ion transport GO:0070838 172 0.407
regulation of nucleotide binding oligomerization domain containing 2 signaling pathway GO:0070432 3 0.405
nitric oxide biosynthetic process GO:0006809 25 0.405
response to bacterial lipoprotein GO:0032493 4 0.405
regulation of stress activated mapk cascade GO:0032872 69 0.404
response to alcohol GO:0097305 48 0.401
cytoplasmic transport GO:0016482 234 0.400
response to growth factor GO:0070848 198 0.397
Human
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.397
activation of immune response GO:0002253 138 0.396
positive regulation of innate immune response GO:0045089 80 0.396
cellular response to acid chemical GO:0071229 68 0.393
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.393
divalent inorganic cation homeostasis GO:0072507 138 0.392
reactive nitrogen species metabolic process GO:2001057 0 0.390
plasma membrane organization GO:0007009 90 0.389
morphogenesis of a branching epithelium GO:0061138 193 0.388
response to molecule of fungal origin GO:0002238 4 0.387
cell matrix adhesion GO:0007160 68 0.386
macrophage apoptotic process GO:0071888 7 0.385
action potential GO:0001508 78 0.384
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.381
positive regulation of granulocyte chemotaxis GO:0071624 12 0.380
neuron projection guidance GO:0097485 141 0.378
positive regulation of transferase activity GO:0051347 167 0.378
inflammatory response GO:0006954 244 0.378
muscle contraction GO:0006936 101 0.377
regulation of nitric oxide synthase biosynthetic process GO:0051769 7 0.376
interleukin 6 mediated signaling pathway GO:0070102 6 0.376
regulation of interleukin 8 production GO:0032677 3 0.376
lymphocyte apoptotic process GO:0070227 54 0.375
cellular response to tumor necrosis factor GO:0071356 21 0.374
antibacterial peptide secretion GO:0002779 1 0.373
actin polymerization or depolymerization GO:0008154 54 0.373
positive regulation of apoptotic cell clearance GO:2000427 3 0.370
transmission of nerve impulse GO:0019226 76 0.370
fibronectin dependent thymocyte migration GO:0072681 1 0.369
positive regulation of alpha beta t cell activation GO:0046635 39 0.368
extracellular matrix dependent thymocyte migration GO:0072680 1 0.368
positive regulation of jnk cascade GO:0046330 46 0.365
positive regulation of coagulation GO:0050820 13 0.364
modulation by virus of host morphology or physiology GO:0019048 3 0.363
interleukin 27 mediated signaling pathway GO:0070106 1 0.359
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.357
positive regulation of lymphocyte proliferation GO:0050671 70 0.354
negative regulation of eosinophil degranulation GO:0043310 1 0.353
protein maturation GO:0051604 176 0.352
Human
interleukin 1 beta secretion GO:0050702 16 0.352
response to acid chemical GO:0001101 111 0.350
regulation of cysteine type endopeptidase activity GO:2000116 65 0.350
Human
regulation of secretion GO:0051046 274 0.349
regulation of homeostatic process GO:0032844 182 0.349
actin cytoskeleton organization GO:0030036 220 0.347
positive regulation of glial cell differentiation GO:0045687 21 0.345
lymphocyte chemotaxis GO:0048247 10 0.343
t cell apoptotic process GO:0070231 39 0.343
purine ribonucleotide metabolic process GO:0009150 290 0.343
positive regulation of behavior GO:0048520 40 0.339
response to sterol GO:0036314 4 0.335
t helper 17 cell chemotaxis GO:0035705 1 0.335
interferon beta biosynthetic process GO:0045350 4 0.333
regulation of protein import into nucleus GO:0042306 52 0.332
positive regulation of lipopolysaccharide mediated signaling pathway GO:0031666 5 0.328
modification by symbiont of host morphology or physiology GO:0044003 4 0.327
ribose phosphate metabolic process GO:0019693 291 0.325
regulation of monocyte chemotaxis GO:0090025 3 0.324
regulation of epithelial cell proliferation GO:0050678 141 0.322
purine nucleoside metabolic process GO:0042278 241 0.322
regulation of adaptive immune response GO:0002819 90 0.319
growth of symbiont involved in interaction with host GO:0044116 23 0.319
regulation of mast cell apoptotic process GO:0033025 5 0.318
intracellular receptor signaling pathway GO:0030522 74 0.315
cytokine secretion GO:0050663 72 0.314
guanosine containing compound metabolic process GO:1901068 144 0.314
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.311

Cd44 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.610
disease of cellular proliferation DOID:14566 0 0.610
organ system cancer DOID:0050686 0 0.610
retinal disease DOID:5679 0 0.319
retinal degeneration DOID:8466 0 0.319
degeneration of macula and posterior pole DOID:2007 0 0.319
sensory system disease DOID:0050155 0 0.319
macular degeneration DOID:4448 0 0.319
disease of anatomical entity DOID:7 0 0.319
eye and adnexa disease DOID:1492 0 0.319
age related macular degeneration DOID:10871 0 0.319
nervous system disease DOID:863 0 0.319
eye disease DOID:5614 0 0.319