Mus musculus

307 known processes

Cdc42

cell division cycle 42 homolog (S. cerevisiae)

(Aliases: AU018915,AI747189)

Cdc42 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton reorganization GO:0031532 21 0.990
Fly
small gtpase mediated signal transduction GO:0007264 97 0.989
Mouse Fly
vacuole organization GO:0007033 38 0.987
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 199 0.987
ras protein signal transduction GO:0007265 77 0.986
Mouse Fly
cytokinesis GO:0000910 17 0.985
Human Worm
regulation of neuron projection development GO:0010975 169 0.984
Fly
regulation of actin cytoskeleton organization GO:0032956 84 0.982
Mouse Fly
establishment of organelle localization GO:0051656 122 0.981
nucleoside phosphate metabolic process GO:0006753 338 0.980
regulation of actin filament based process GO:0032970 99 0.980
Mouse Worm Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.979
Human Fly
ribonucleoside metabolic process GO:0009119 245 0.979
regulation of neuron differentiation GO:0045664 281 0.977
Fly
negative regulation of actin filament depolymerization GO:0030835 9 0.968
organelle assembly GO:0070925 177 0.968
barbed end actin filament capping GO:0051016 6 0.964
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.963
regulation of anatomical structure size GO:0090066 178 0.961
Mouse Fly
ribose phosphate metabolic process GO:0019693 291 0.959
ribonucleotide catabolic process GO:0009261 208 0.958
regulation of cellular component size GO:0032535 121 0.958
Mouse Fly
activation of mapkkk activity GO:0000185 1 0.958
organonitrogen compound catabolic process GO:1901565 264 0.957
organic cyclic compound catabolic process GO:1901361 295 0.951
epithelial cell development GO:0002064 159 0.947
regulation of cellular ketone metabolic process GO:0010565 66 0.946
regulation of cellular amino acid metabolic process GO:0006521 5 0.944
sensory perception of touch GO:0050975 2 0.941
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.940
regulation of cytoskeleton organization GO:0051493 122 0.939
Human Mouse Fly
regulation of nucleotide metabolic process GO:0006140 169 0.934
microtubule based movement GO:0007018 84 0.932
Rat
guanosine containing compound catabolic process GO:1901069 144 0.931
intracellular protein transport GO:0006886 204 0.926
Rat
ribonucleoside catabolic process GO:0042454 206 0.925
purine nucleoside triphosphate catabolic process GO:0009146 203 0.925
regionalization GO:0003002 337 0.924
nucleoside phosphate catabolic process GO:1901292 222 0.922
purine nucleoside metabolic process GO:0042278 241 0.921
developmental maturation GO:0021700 193 0.921
oocyte construction GO:0007308 2 0.919
regulation of intracellular transport GO:0032386 159 0.917
Rat
positive regulation of nucleoside metabolic process GO:0045979 91 0.914
mapk cascade GO:0000165 281 0.912
positive regulation of protein phosphorylation GO:0001934 242 0.910
central nervous system neuron differentiation GO:0021953 162 0.903
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.901
carbohydrate derivative catabolic process GO:1901136 231 0.898
nucleotide metabolic process GO:0009117 332 0.898
positive regulation of neuron differentiation GO:0045666 141 0.897
cell division GO:0051301 120 0.897
cell growth GO:0016049 130 0.892
Yeast
ribonucleotide metabolic process GO:0009259 291 0.892
synaptic transmission GO:0007268 329 0.891
Rat Fly
purine nucleotide catabolic process GO:0006195 211 0.890
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.888
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.887
regulation of cellular component biogenesis GO:0044087 181 0.887
Human Yeast Mouse Fly
cell junction maintenance GO:0034331 4 0.884
oocyte axis specification GO:0007309 2 0.883
synaptic vesicle localization GO:0097479 59 0.882
branching morphogenesis of an epithelial tube GO:0048754 159 0.880
Fly
regulation of peptidyl serine phosphorylation GO:0033135 39 0.875
engulfment of apoptotic cell GO:0043652 3 0.875
Mouse
non canonical wnt signaling pathway GO:0035567 33 0.874
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.873
Human
nucleoside catabolic process GO:0009164 206 0.862
microtubule cytoskeleton organization GO:0000226 157 0.857
Human Worm
positive regulation of cell development GO:0010720 237 0.857
Human
regulation of cellular amine metabolic process GO:0033238 20 0.856
regulation of ras protein signal transduction GO:0046578 114 0.854
organophosphate catabolic process GO:0046434 232 0.849
cell maturation GO:0048469 127 0.847
positive regulation of nervous system development GO:0051962 221 0.844
jnk cascade GO:0007254 72 0.843
Rat
regulation of protein localization GO:0032880 231 0.842
Human Yeast Rat
cellular nitrogen compound catabolic process GO:0044270 280 0.839
positive regulation of map kinase activity GO:0043406 84 0.839
nuclear division GO:0000280 158 0.837
nucleobase containing small molecule metabolic process GO:0055086 352 0.836
purine containing compound metabolic process GO:0072521 311 0.833
purine ribonucleoside catabolic process GO:0046130 205 0.833
microtubule based process GO:0007017 236 0.832
Human Rat Worm
organelle localization GO:0051640 179 0.831
protein localization to membrane GO:0072657 108 0.824
Mouse
amine metabolic process GO:0009308 45 0.823
peptidyl serine phosphorylation GO:0018105 74 0.818
developmental cell growth GO:0048588 84 0.816
nucleoside triphosphate catabolic process GO:0009143 205 0.816
regulation of actin filament polymerization GO:0030833 38 0.814
Mouse Fly
neuron projection extension GO:1990138 64 0.799
hair follicle placode formation GO:0060789 5 0.799
stress activated protein kinase signaling cascade GO:0031098 81 0.797
Rat
regulation of actin filament depolymerization GO:0030834 13 0.797
regulation of organelle organization GO:0033043 289 0.790
regulation of protein kinase activity GO:0045859 232 0.788
purine nucleoside triphosphate metabolic process GO:0009144 226 0.788
regulation of lamellipodium assembly GO:0010591 3 0.779
Mouse Fly
regulation of gtp catabolic process GO:0033124 113 0.777
regulation of establishment of protein localization GO:0070201 181 0.777
Rat
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.775
Mouse
positive regulation of cell projection organization GO:0031346 95 0.775
Human Mouse Fly
positive regulation of gtp catabolic process GO:0033126 85 0.774
positive regulation of neuron projection development GO:0010976 79 0.773
regulation of ras gtpase activity GO:0032318 88 0.763
purine containing compound catabolic process GO:0072523 213 0.761
protein localization to organelle GO:0033365 185 0.761
glycosyl compound metabolic process GO:1901657 246 0.758
regulation of mitotic cell cycle GO:0007346 126 0.757
neural precursor cell proliferation GO:0061351 121 0.751
Fly
regulation of hair follicle cell proliferation GO:0071336 2 0.746
pallium development GO:0021543 120 0.742
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.740
positive regulation of cellular component biogenesis GO:0044089 94 0.738
Human Mouse Fly
olfactory bulb development GO:0021772 30 0.737
Mouse
cellular amine metabolic process GO:0044106 44 0.734
guanosine containing compound metabolic process GO:1901068 144 0.729
regulation of cell projection organization GO:0031344 206 0.726
Human Yeast Mouse Fly
positive regulation of cell death GO:0010942 224 0.726
Rat
cell cell junction organization GO:0045216 72 0.725
epithelial tube morphogenesis GO:0060562 303 0.723
Fly
positive regulation of filopodium assembly GO:0051491 10 0.721
Fly
regulation of purine nucleotide catabolic process GO:0033121 122 0.720
positive regulation of kinase activity GO:0033674 155 0.719
mitotic cell cycle GO:0000278 195 0.718
regulation of protein transport GO:0051223 163 0.715
Rat
positive regulation of programmed cell death GO:0043068 218 0.710
Rat
intracellular mrna localization GO:0008298 4 0.710
regulation of kinase activity GO:0043549 249 0.708
actin filament capping GO:0051693 6 0.703
purine ribonucleoside metabolic process GO:0046128 241 0.700
morphogenesis of a polarized epithelium GO:0001738 37 0.699
Mouse
cellular ketone metabolic process GO:0042180 84 0.698
positive regulation of intracellular protein transport GO:0090316 42 0.693
Rat
pole plasm assembly GO:0007315 2 0.693
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.688
regulation of mapk cascade GO:0043408 248 0.685
protein polymerization GO:0051258 57 0.684
Mouse Fly
regulation of cell cycle process GO:0010564 160 0.680
arp2 3 complex mediated actin nucleation GO:0034314 3 0.678
negative regulation of protein complex disassembly GO:0043242 22 0.676
nucleoside metabolic process GO:0009116 246 0.675
regulation of filopodium assembly GO:0051489 13 0.674
Human Fly
positive regulation of actin filament bundle assembly GO:0032233 11 0.673
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.669
Fly
synaptic vesicle transport GO:0048489 57 0.669
keratinocyte differentiation GO:0030216 48 0.666
glycosyl compound catabolic process GO:1901658 206 0.663
sterol transmembrane transport GO:0035382 2 0.663
embryonic organ morphogenesis GO:0048562 276 0.663
Mouse
positive regulation of growth GO:0045927 104 0.660
oocyte anterior posterior axis specification GO:0007314 2 0.655
regulation of hydrolase activity GO:0051336 246 0.650
synapse organization GO:0050808 125 0.647
Rat Fly
aromatic compound catabolic process GO:0019439 286 0.647
actin filament depolymerization GO:0030042 15 0.646
regulation of jnk cascade GO:0046328 62 0.645
Rat
positive regulation of protein modification process GO:0031401 299 0.642
regulation of transferase activity GO:0051338 263 0.642
regulation of cellular response to stress GO:0080135 159 0.640
Rat
terminal button organization GO:0072553 3 0.637
mitotic cell cycle process GO:1903047 159 0.632
regulation of protein targeting GO:1903533 61 0.632
cation homeostasis GO:0055080 212 0.632
ameboidal type cell migration GO:0001667 128 0.624
Zebrafish
rho protein signal transduction GO:0007266 32 0.621
Mouse Fly
endomembrane system organization GO:0010256 147 0.615
Mouse Rat
regulation of actin filament length GO:0030832 45 0.610
Mouse Fly
stem cell development GO:0048864 219 0.608
meiotic cell cycle GO:0051321 122 0.608
positive regulation of nucleotide catabolic process GO:0030813 88 0.605
actin filament organization GO:0007015 113 0.601
actin filament polymerization GO:0030041 44 0.597
Mouse Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.596
positive regulation of cell growth GO:0030307 33 0.595
developmental growth involved in morphogenesis GO:0060560 138 0.592
axonogenesis GO:0007409 274 0.589
Mouse Fly
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.587
osmosensory signaling pathway GO:0007231 1 0.583
cellular component assembly involved in morphogenesis GO:0010927 139 0.577
Yeast Fly
regulation of exit from mitosis GO:0007096 1 0.572
Yeast
phagocytosis GO:0006909 66 0.572
Mouse Fly
cellular response to osmotic stress GO:0071470 7 0.571
cellular protein complex assembly GO:0043623 116 0.569
Mouse Fly
nucleotide catabolic process GO:0009166 217 0.563
regulation of cell growth GO:0001558 91 0.562
regulation of cell migration GO:0030334 219 0.561
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.561
peptidyl amino acid modification GO:0018193 336 0.560
cellular amino acid metabolic process GO:0006520 103 0.560
anatomical structure homeostasis GO:0060249 145 0.559
protein localization to nucleus GO:0034504 121 0.559
regulation of intracellular protein transport GO:0033157 82 0.557
Rat
positive regulation of rho gtpase activity GO:0032321 41 0.556
positive regulation of nucleotide metabolic process GO:0045981 114 0.556
telencephalon development GO:0021537 186 0.555
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.553
cellular homeostasis GO:0019725 240 0.553
purine ribonucleotide metabolic process GO:0009150 290 0.549
regulation of actin filament bundle assembly GO:0032231 18 0.549
hair follicle cell proliferation GO:0071335 3 0.548
forebrain development GO:0030900 302 0.542
Mouse
neurotransmitter secretion GO:0007269 62 0.539
morphogenesis of a branching epithelium GO:0061138 193 0.539
Fly
positive regulation of hair follicle cell proliferation GO:0071338 1 0.538
adherens junction maintenance GO:0034334 1 0.537
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.533
germ cell development GO:0007281 185 0.529
Fly
positive regulation of protein kinase activity GO:0045860 144 0.529
Fly
stress activated mapk cascade GO:0051403 80 0.528
Rat
regulation of protein serine threonine kinase activity GO:0071900 157 0.525
single organismal cell cell adhesion GO:0016337 131 0.521
regulation of establishment of planar polarity GO:0090175 28 0.520
Mouse
multicellular organism growth GO:0035264 161 0.520
regulation of protein heterodimerization activity GO:0043497 2 0.518
morphogenesis of embryonic epithelium GO:0016331 159 0.518
Fly
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.516
regulation of cell adhesion GO:0030155 154 0.515
Human
membrane organization GO:0061024 245 0.514
Yeast Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.512
positive regulation of stress fiber assembly GO:0051496 9 0.510
regulation of mitosis GO:0007088 29 0.510
gtp catabolic process GO:0006184 143 0.504
positive regulation of cellular catabolic process GO:0031331 148 0.504
positive regulation of apoptotic process GO:0043065 217 0.502
Rat
positive regulation of substrate adhesion dependent cell spreading GO:1900026 8 0.501
Human
mitochondrion distribution GO:0048311 4 0.500
sterol transport GO:0015918 38 0.499
mechanoreceptor differentiation GO:0042490 67 0.498
Mouse
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.496
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.496
regulation of membrane potential GO:0042391 192 0.492
positive regulation of lamellipodium assembly GO:0010592 2 0.486
Mouse Fly
epithelial cell morphogenesis GO:0003382 41 0.481
Mouse
regulation of secretion GO:0051046 274 0.479
Yeast
dendritic spine organization GO:0097061 26 0.479
nucleus localization GO:0051647 20 0.471
wnt signaling pathway GO:0016055 188 0.467
establishment of synaptic vesicle localization GO:0097480 57 0.467
hair follicle morphogenesis GO:0031069 29 0.464
positive regulation of cytoplasmic transport GO:1903651 40 0.461
neuron fate determination GO:0048664 9 0.459
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.457
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.456
regulation of body fluid levels GO:0050878 162 0.450
stem cell differentiation GO:0048863 268 0.448
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.446
Mouse
regulation of secretion by cell GO:1903530 249 0.445
Yeast
myeloid cell differentiation GO:0030099 233 0.445
establishment of vesicle localization GO:0051650 81 0.444
cell type specific apoptotic process GO:0097285 268 0.442
Rat
oogenesis GO:0048477 56 0.438
Fly
lamellipodium organization GO:0097581 29 0.437
Mouse Fly
gland development GO:0048732 330 0.436
Rat
heterocycle catabolic process GO:0046700 280 0.436
regulation of nucleotide catabolic process GO:0030811 122 0.432
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.429
vesicle localization GO:0051648 86 0.421
negative regulation of synaptic vesicle transport GO:1902804 3 0.421
protein import into nucleus GO:0006606 95 0.419
circulatory system process GO:0003013 197 0.419
regulation of substrate adhesion dependent cell spreading GO:1900024 12 0.418
Human
regulation of purine nucleotide metabolic process GO:1900542 169 0.414
negative regulation of cell proliferation involved in contact inhibition GO:0060244 3 0.411
positive regulation of dendrite development GO:1900006 21 0.404
female gamete generation GO:0007292 74 0.402
Fly
regulation of stress fiber assembly GO:0051492 15 0.401
positive regulation of mapk cascade GO:0043410 170 0.398
neuron migration GO:0001764 122 0.397
digestive tract development GO:0048565 190 0.396
Zebrafish
positive regulation of lamellipodium organization GO:1902745 3 0.389
Mouse Fly
positive regulation of transferase activity GO:0051347 167 0.389
contact inhibition GO:0060242 3 0.383
cell junction assembly GO:0034329 52 0.383
cellular response to abiotic stimulus GO:0071214 56 0.382
membrane fusion GO:0061025 38 0.381
Yeast
organelle fission GO:0048285 170 0.380
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.380
synapse assembly GO:0007416 56 0.372
Fly
neuron maturation GO:0042551 29 0.368
regulation of cell motility GO:2000145 236 0.368
Mouse
actomyosin structure organization GO:0031032 56 0.367
meiotic cell cycle process GO:1903046 77 0.363
oocyte differentiation GO:0009994 35 0.356
protein import GO:0017038 101 0.355
stem cell proliferation GO:0072089 117 0.354
Fly
morphogenesis of a branching structure GO:0001763 203 0.354
Fly
spindle localization GO:0051653 22 0.353
Worm
response to osmotic stress GO:0006970 21 0.352
Mouse
meiotic nuclear division GO:0007126 115 0.348
regulation of protein import into nucleus GO:0042306 52 0.346
gtp metabolic process GO:0046039 144 0.343
positive regulation of organelle organization GO:0010638 128 0.338
Mouse
lipid localization GO:0010876 126 0.337
positive regulation of hydrolase activity GO:0051345 148 0.335
protein targeting GO:0006605 143 0.332
regulation of vesicle mediated transport GO:0060627 139 0.329
Yeast
keratinization GO:0031424 9 0.326
positive regulation of gtpase activity GO:0043547 85 0.325
response to organonitrogen compound GO:0010243 246 0.321
filopodium assembly GO:0046847 19 0.318
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.317
determination of digestive tract left right asymmetry GO:0071907 1 0.315
ectodermal digestive tract development GO:0007439 1 0.310
determination of left right symmetry GO:0007368 80 0.310
canonical wnt signaling pathway GO:0060070 130 0.309
blood circulation GO:0008015 195 0.308
negative regulation of cell projection organization GO:0031345 56 0.306
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.306
regulation of map kinase activity GO:0043405 120 0.298
exocytosis GO:0006887 121 0.297
Yeast
regulation of synaptic plasticity GO:0048167 87 0.290
regulation of neurotransmitter levels GO:0001505 87 0.288
protein autophosphorylation GO:0046777 61 0.287
muscle cell development GO:0055001 133 0.287
regulation of protein complex assembly GO:0043254 83 0.286
Human Mouse Fly
positive regulation of cell migration GO:0030335 109 0.284
Mouse
negative regulation of cell proliferation GO:0008285 296 0.284
blood vessel morphogenesis GO:0048514 285 0.284
Rat
cytoplasmic transport GO:0016482 234 0.283
heart morphogenesis GO:0003007 178 0.280
carbohydrate derivative biosynthetic process GO:1901137 183 0.280
regulation of rho protein signal transduction GO:0035023 71 0.279
cell adhesion GO:0007155 329 0.277
dopaminergic neuron differentiation GO:0071542 14 0.276
Mouse
muscle tissue development GO:0060537 308 0.276
calcium ion homeostasis GO:0055074 127 0.276
myeloid leukocyte differentiation GO:0002573 119 0.275
regulation of exocytosis GO:0017157 61 0.274
Yeast
organonitrogen compound biosynthetic process GO:1901566 192 0.273
organ growth GO:0035265 117 0.272
lateral inhibition GO:0046331 1 0.271
myotube differentiation GO:0014902 105 0.269
regulation of hormone levels GO:0010817 211 0.267
immune response regulating cell surface receptor signaling pathway involved in phagocytosis GO:0002433 1 0.266
inner ear receptor cell differentiation GO:0060113 61 0.265
Mouse
forebrain cell migration GO:0021885 58 0.263
Mouse
nitrogen compound transport GO:0071705 271 0.260
protein localization to plasma membrane GO:0072659 57 0.256
Mouse
gliogenesis GO:0042063 141 0.256
axon extension involved in axon guidance GO:0048846 14 0.253
dna metabolic process GO:0006259 303 0.253
Rat
g protein coupled receptor signaling pathway GO:0007186 243 0.251
Yeast Mouse
autophagy GO:0006914 45 0.251
establishment of endothelial blood brain barrier GO:0014045 3 0.251
negative regulation of protein depolymerization GO:1901880 21 0.251
regulation of protein catabolic process GO:0042176 108 0.250
segmentation GO:0035282 93 0.250
molting cycle GO:0042303 90 0.249
positive regulation of jnk cascade GO:0046330 46 0.248
Rat
syncytium formation GO:0006949 43 0.248
regulation of cell division GO:0051302 76 0.248
regulation of protein kinase c signaling GO:0090036 5 0.247
notch signaling pathway GO:0007219 71 0.246
cell junction organization GO:0034330 77 0.244
regulation of lipid metabolic process GO:0019216 118 0.244
organic hydroxy compound transport GO:0015850 93 0.243
cerebral cortex radially oriented cell migration GO:0021799 31 0.240
Mouse
axon guidance GO:0007411 141 0.240
Mouse Fly
regulation of cellular catabolic process GO:0031329 242 0.240
positive regulation of chemotaxis GO:0050921 38 0.239
Mouse
plasma membrane organization GO:0007009 90 0.239
Mouse
epidermis development GO:0008544 187 0.236
chromosome segregation GO:0007059 48 0.235
Human
regulation of synapse assembly GO:0051963 29 0.230
Fly
actin cytoskeleton organization GO:0030036 220 0.229
hair follicle development GO:0001942 85 0.229
dorsal ventral axon guidance GO:0033563 3 0.227
forebrain neuron development GO:0021884 30 0.225
Mouse
neuron death GO:0070997 154 0.224
Rat
regulation of cell size GO:0008361 72 0.224
purine containing compound biosynthetic process GO:0072522 70 0.223
cellular chemical homeostasis GO:0055082 215 0.222
wound healing GO:0042060 157 0.221
Fly
appendage development GO:0048736 166 0.221
Fly
cellular response to organonitrogen compound GO:0071417 145 0.219
regulation of cell cycle GO:0051726 281 0.218
chemotaxis GO:0006935 247 0.218
Mouse Fly
regulation of neural precursor cell proliferation GO:2000177 70 0.217
forebrain neuron differentiation GO:0021879 52 0.215
Mouse
amide transport GO:0042886 138 0.212
substrate dependent cell migration cell extension GO:0006930 4 0.212
gonad development GO:0008406 141 0.211
Worm
localization within membrane GO:0051668 4 0.210
purine nucleotide biosynthetic process GO:0006164 65 0.208
multi multicellular organism process GO:0044706 109 0.206
embryonic appendage morphogenesis GO:0035113 126 0.206
cerebral cortex cell migration GO:0021795 44 0.206
Mouse
cell fate specification GO:0001708 72 0.205
endothelium development GO:0003158 45 0.202
maintenance of location GO:0051235 89 0.202
Human Fly
positive regulation of intracellular transport GO:0032388 70 0.202
Rat
neural tube formation GO:0001841 108 0.200
appendage morphogenesis GO:0035107 149 0.197
Fly
limbic system development GO:0021761 72 0.196
muscle cell differentiation GO:0042692 261 0.195
positive regulation of secretion by cell GO:1903532 114 0.194
Yeast
regulation of organ morphogenesis GO:2000027 144 0.192
Mouse
positive regulation of synapse assembly GO:0051965 18 0.189
nucleotide biosynthetic process GO:0009165 78 0.189
keratinocyte development GO:0003334 10 0.189
neural tube development GO:0021915 160 0.189
regulation of cell projection assembly GO:0060491 38 0.187
Human Yeast Mouse Fly
heart process GO:0003015 94 0.186
hair cell differentiation GO:0035315 40 0.185
Mouse Fly
regulation of jun kinase activity GO:0043506 40 0.185
positive regulation of jun kinase activity GO:0043507 30 0.184
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.184
neuron projection guidance GO:0097485 141 0.182
Mouse Fly
immune effector process GO:0002252 321 0.180
Fly
epithelial cell proliferation GO:0050673 174 0.180
establishment of protein localization to organelle GO:0072594 118 0.179
apoptotic signaling pathway GO:0097190 306 0.178
camera type eye development GO:0043010 266 0.178
Mouse
positive regulation of protein transport GO:0051222 93 0.177
Rat
forebrain generation of neurons GO:0021872 63 0.176
Mouse
heart contraction GO:0060047 93 0.176
tissue homeostasis GO:0001894 115 0.175
chromosome movement towards spindle pole GO:0051305 3 0.175
cerebral cortex development GO:0021987 86 0.175
Mouse
negative regulation of actin filament polymerization GO:0030837 11 0.172
glial cell migration GO:0008347 7 0.170
regulation of protein stability GO:0031647 52 0.170
cellular calcium ion homeostasis GO:0006874 119 0.169
positive regulation of secretion GO:0051047 130 0.168
Yeast
negative regulation of wnt signaling pathway GO:0030178 73 0.168
ion transmembrane transport GO:0034220 361 0.168
multicellular organismal homeostasis GO:0048871 164 0.167
acetylcholine secretion neurotransmission GO:0014055 2 0.167
neurotransmitter transport GO:0006836 76 0.164
sensory perception of mechanical stimulus GO:0050954 107 0.163
Fly
skeletal system development GO:0001501 356 0.163
skeletal system morphogenesis GO:0048705 203 0.162
regulation of protein localization to nucleus GO:1900180 60 0.162
olfactory bulb interneuron development GO:0021891 7 0.162
Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.161
regulation of nucleotide biosynthetic process GO:0030808 34 0.161
dendrite development GO:0016358 115 0.160
Mouse Fly
lipid transport GO:0006869 98 0.159
development of primary sexual characteristics GO:0045137 143 0.158
Worm
organophosphate biosynthetic process GO:0090407 122 0.158
adherens junction organization GO:0034332 28 0.158
negative regulation of exocytosis GO:0045920 12 0.156
skin morphogenesis GO:0043589 38 0.155
single organism nuclear import GO:1902593 95 0.155
regulation of neuron death GO:1901214 134 0.155
Rat
epithelial mesenchymal cell signaling GO:0060684 7 0.153
syncytium formation by plasma membrane fusion GO:0000768 42 0.152
tissue remodeling GO:0048771 102 0.151
mitotic nuclear division GO:0007067 48 0.151
cardiac muscle contraction GO:0060048 32 0.150
asymmetric neuroblast division GO:0055059 1 0.150
Fly
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.149
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.148
regulation of nuclear division GO:0051783 56 0.147
regulation of respiratory burst GO:0060263 2 0.147
cellular lipid metabolic process GO:0044255 323 0.147
neuron neuron synaptic transmission GO:0007270 69 0.147
positive regulation of protein export from nucleus GO:0046827 4 0.146
endochondral bone morphogenesis GO:0060350 50 0.146
regulation of blood circulation GO:1903522 93 0.146
cyclic nucleotide biosynthetic process GO:0009190 44 0.144
negative regulation of molecular function GO:0044092 258 0.143
nucleoside phosphate biosynthetic process GO:1901293 79 0.143
positive regulation of stress activated mapk cascade GO:0032874 48 0.143
Rat
positive regulation of behavior GO:0048520 40 0.142
Mouse
regulation of organ growth GO:0046620 61 0.141
genetic imprinting GO:0071514 27 0.141
regulation of cell shape GO:0008360 39 0.140
Mouse Fly
cellular response to starvation GO:0009267 57 0.139
cardiac muscle tissue development GO:0048738 130 0.138
digestive system development GO:0055123 200 0.137
Zebrafish
positive regulation of cell adhesion GO:0045785 80 0.137
Human
limb morphogenesis GO:0035108 149 0.135
regulation of neuronal synaptic plasticity GO:0048168 30 0.134
metencephalon development GO:0022037 89 0.133
learning or memory GO:0007611 148 0.132
axonal fasciculation GO:0007413 15 0.132
neuroblast proliferation GO:0007405 49 0.132
Fly
regulation of neurotransmitter secretion GO:0046928 29 0.129
intracellular distribution of mitochondria GO:0048312 1 0.129
regulation of camp biosynthetic process GO:0030817 25 0.129
purine nucleoside catabolic process GO:0006152 205 0.129
phospholipid metabolic process GO:0006644 87 0.128
peptidyl serine modification GO:0018209 83 0.127
cell fate commitment GO:0045165 210 0.126
regulation of system process GO:0044057 200 0.124
ear morphogenesis GO:0042471 118 0.124
Mouse
cell chemotaxis GO:0060326 81 0.124
Mouse
divalent inorganic cation transport GO:0072511 178 0.124
purine ribonucleotide biosynthetic process GO:0009152 59 0.123
telencephalon cell migration GO:0022029 55 0.121
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.121
negative regulation of interleukin 23 production GO:0032707 1 0.120

Cdc42 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.152
disease of anatomical entity DOID:7 0 0.152
neurodegenerative disease DOID:1289 0 0.152
nervous system disease DOID:863 0 0.152