Mus musculus

0 known processes

Cdc45

cell division cycle 45 homolog (S. cerevisiae)

(Aliases: Cdc45l)

Cdc45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.644
Yeast Fly
dna repair GO:0006281 107 0.443
Yeast
cellular response to dna damage stimulus GO:0006974 207 0.307
Yeast Fly
dna recombination GO:0006310 92 0.260
Yeast
dna dependent dna replication GO:0006261 24 0.228
Yeast
nuclear dna replication GO:0033260 3 0.185
Yeast
meiotic nuclear division GO:0007126 115 0.152
regulation of cell cycle process GO:0010564 160 0.147
Fly
macromolecule catabolic process GO:0009057 281 0.146
meiotic cell cycle process GO:1903046 77 0.138
regulation of cell cycle GO:0051726 281 0.137
Fly
negative regulation of cell cycle phase transition GO:1901988 48 0.129
Fly
meiotic cell cycle GO:0051321 122 0.118
nuclear division GO:0000280 158 0.112
dna replication initiation GO:0006270 5 0.109
Yeast
meiosis i GO:0007127 60 0.109
dna conformation change GO:0071103 37 0.101
Fly
mitotic chromosome condensation GO:0007076 1 0.097
microtubule cytoskeleton organization GO:0000226 157 0.096
dna packaging GO:0006323 30 0.092
Fly
regulation of mitotic cell cycle phase transition GO:1901990 73 0.090
Fly
mitotic cell cycle checkpoint GO:0007093 31 0.088
Fly
organelle assembly GO:0070925 177 0.083
purine nucleotide metabolic process GO:0006163 302 0.082
nucleoside phosphate catabolic process GO:1901292 222 0.081
development of primary sexual characteristics GO:0045137 143 0.079
metaphase plate congression GO:0051310 2 0.079
regulation of cell cycle phase transition GO:1901987 77 0.079
Fly
organelle localization GO:0051640 179 0.077
establishment of organelle localization GO:0051656 122 0.076
dna replication GO:0006260 52 0.074
Yeast Fly
mitotic sister chromatid segregation GO:0000070 14 0.074
cellular protein catabolic process GO:0044257 155 0.071
chromatin organization GO:0006325 206 0.068
protein catabolic process GO:0030163 221 0.066
mitotic cell cycle GO:0000278 195 0.066
Fly
heterocycle catabolic process GO:0046700 280 0.065
protein depolymerization GO:0051261 34 0.065
intracellular protein transport GO:0006886 204 0.063
dna endoreduplication GO:0042023 4 0.062
microtubule based process GO:0007017 236 0.059
fertilization GO:0009566 127 0.059
nucleoside phosphate metabolic process GO:0006753 338 0.058
cellular amine metabolic process GO:0044106 44 0.058
mitotic cytokinesis GO:0000281 4 0.057
recombinational repair GO:0000725 21 0.057
Yeast
negative regulation of cell cycle GO:0045786 123 0.057
Fly
cellular ketone metabolic process GO:0042180 84 0.057
synapsis GO:0007129 34 0.056
double strand break repair GO:0006302 48 0.054
Yeast
mitotic cell cycle process GO:1903047 159 0.054
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
modification dependent protein catabolic process GO:0019941 133 0.053
posttranscriptional regulation of gene expression GO:0010608 155 0.053
protein ubiquitination GO:0016567 171 0.053
protein localization to organelle GO:0033365 185 0.052
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.052
positive regulation of cell cycle GO:0045787 92 0.052
Fly
response to cell cycle checkpoint signaling GO:0072396 1 0.052
meiotic chromosome segregation GO:0045132 19 0.051
modification dependent macromolecule catabolic process GO:0043632 133 0.049
double strand break repair via homologous recombination GO:0000724 21 0.048
Yeast
nucleoside triphosphate metabolic process GO:0009141 230 0.047
negative regulation of mitotic cell cycle GO:0045930 58 0.047
Fly
cytokinetic process GO:0032506 2 0.046
organic cyclic compound catabolic process GO:1901361 295 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.045
regulation of chromosome organization GO:0033044 83 0.045
ribose phosphate metabolic process GO:0019693 291 0.045
cellular amino acid metabolic process GO:0006520 103 0.045
male meiosis GO:0007140 37 0.045
proteasomal protein catabolic process GO:0010498 98 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
regulation of protein localization GO:0032880 231 0.044
reciprocal dna recombination GO:0035825 16 0.043
cellular macromolecule catabolic process GO:0044265 206 0.042
regulation of nuclear cell cycle dna replication GO:0033262 2 0.042
spindle assembly involved in mitosis GO:0090307 4 0.042
female meiosis chromosome segregation GO:0016321 1 0.042
organelle fission GO:0048285 170 0.041
purine ribonucleotide catabolic process GO:0009154 208 0.041
cellular protein complex assembly GO:0043623 116 0.040
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.040
Fly
purine nucleoside monophosphate catabolic process GO:0009128 58 0.038
cellular component assembly involved in morphogenesis GO:0010927 139 0.037
regulation of cellular response to stress GO:0080135 159 0.037
establishment of protein localization to organelle GO:0072594 118 0.037
protein modification by small protein conjugation or removal GO:0070647 207 0.036
purine containing compound metabolic process GO:0072521 311 0.035
membrane organization GO:0061024 245 0.034
aromatic compound catabolic process GO:0019439 286 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
reciprocal meiotic recombination GO:0007131 16 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
spermatogenesis GO:0007283 284 0.034
amine metabolic process GO:0009308 45 0.034
endomembrane system organization GO:0010256 147 0.033
cytoplasmic transport GO:0016482 234 0.033
cytokinesis GO:0000910 17 0.033
peptidyl serine modification GO:0018209 83 0.033
sister chromatid segregation GO:0000819 20 0.033
germ cell development GO:0007281 185 0.033
purine nucleoside catabolic process GO:0006152 205 0.032
gonad development GO:0008406 141 0.032
purine containing compound catabolic process GO:0072523 213 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
regulation of mitotic sister chromatid segregation GO:0033047 12 0.032
cell division GO:0051301 120 0.032
regulation of cellular catabolic process GO:0031329 242 0.031
chromosome segregation GO:0007059 48 0.031
striated muscle myosin thick filament assembly GO:0071688 1 0.031
female gamete generation GO:0007292 74 0.031
multicellular organism growth GO:0035264 161 0.031
regulation of cell division GO:0051302 76 0.031
negative regulation of cellular component organization GO:0051129 194 0.030
maintenance of location GO:0051235 89 0.030
ubiquitin dependent protein catabolic process GO:0006511 129 0.030
protein import GO:0017038 101 0.030
histone modification GO:0016570 159 0.030
chromosome condensation GO:0030261 10 0.030
Fly
cation transport GO:0006812 399 0.030
spindle assembly involved in meiosis GO:0090306 4 0.029
mitotic centrosome separation GO:0007100 4 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
regulation of kinase activity GO:0043549 249 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
ribonucleoside metabolic process GO:0009119 245 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
nucleocytoplasmic transport GO:0006913 139 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
regulation of cytokine production GO:0001817 266 0.028
regulation of mitosis GO:0007088 29 0.028
purine nucleotide catabolic process GO:0006195 211 0.028
organonitrogen compound catabolic process GO:1901565 264 0.027
immune effector process GO:0002252 321 0.027
regulation of binding GO:0051098 111 0.026
protein targeting GO:0006605 143 0.026
dna integrity checkpoint GO:0031570 28 0.026
Fly
male gamete generation GO:0048232 285 0.026
regulation of organelle organization GO:0033043 289 0.026
regulation of establishment of protein localization GO:0070201 181 0.025
single fertilization GO:0007338 82 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
peptidyl serine phosphorylation GO:0018105 74 0.025
myosin filament organization GO:0031033 3 0.025
nucleotide metabolic process GO:0009117 332 0.024
cell maturation GO:0048469 127 0.024
centrosome separation GO:0051299 4 0.024
mitotic nuclear division GO:0007067 48 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
regulation of spindle organization GO:0090224 2 0.024
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
regulation of protein kinase activity GO:0045859 232 0.024
negative regulation of organelle organization GO:0010639 90 0.024
genitalia development GO:0048806 37 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
organophosphate catabolic process GO:0046434 232 0.023
negative regulation of molecular function GO:0044092 258 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
leukocyte mediated immunity GO:0002443 174 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
dephosphorylation GO:0016311 129 0.023
apoptotic signaling pathway GO:0097190 306 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
peptidyl amino acid modification GO:0018193 336 0.023
regulation of protein binding GO:0043393 60 0.023
positive regulation of cell development GO:0010720 237 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
Fly
negative regulation of cell proliferation GO:0008285 296 0.022
response to organic cyclic compound GO:0014070 198 0.022
single organism nuclear import GO:1902593 95 0.022
cleavage furrow formation GO:0036089 2 0.022
regulation of cellular ketone metabolic process GO:0010565 66 0.022
lymphocyte differentiation GO:0030098 242 0.022
covalent chromatin modification GO:0016569 163 0.022
cellular response to abiotic stimulus GO:0071214 56 0.022
negative regulation of cell cycle process GO:0010948 69 0.022
Fly
cell cycle checkpoint GO:0000075 47 0.021
Fly
chromosome organization involved in meiosis GO:0070192 39 0.021
cell type specific apoptotic process GO:0097285 268 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
regulation of proteasomal protein catabolic process GO:0061136 46 0.020
dna damage checkpoint GO:0000077 26 0.020
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.020
regulation of protein catabolic process GO:0042176 108 0.020
atp catabolic process GO:0006200 55 0.020
regionalization GO:0003002 337 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
endocytosis GO:0006897 168 0.020
t cell activation GO:0042110 289 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
negative regulation of mitosis GO:0045839 10 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.019
protein import into nucleus GO:0006606 95 0.019
regulation of protein transport GO:0051223 163 0.019
striated muscle tissue development GO:0014706 293 0.019
regulation of exit from mitosis GO:0007096 1 0.019
t cell proliferation GO:0042098 120 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.019
chromatin modification GO:0016568 187 0.019
spindle localization GO:0051653 22 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.018
myosin filament assembly GO:0031034 2 0.018
regulation of mitotic spindle organization GO:0060236 2 0.018
establishment or maintenance of cell polarity GO:0007163 86 0.018
centrosome cycle GO:0007098 23 0.018
regulation of cell motility GO:2000145 236 0.018
divalent metal ion transport GO:0070838 172 0.018
g1 s transition of mitotic cell cycle GO:0000082 57 0.018
Fly
nucleoside metabolic process GO:0009116 246 0.017
microtubule based movement GO:0007018 84 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.017
regulation of double strand break repair via homologous recombination GO:0010569 2 0.017
camera type eye development GO:0043010 266 0.017
negative regulation of binding GO:0051100 39 0.017
cellular lipid metabolic process GO:0044255 323 0.017
oocyte maturation GO:0001556 18 0.017
muscle tissue development GO:0060537 308 0.016
homeostasis of number of cells GO:0048872 210 0.016
positive regulation of cellular protein catabolic process GO:1903364 34 0.016
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
cellular homeostasis GO:0019725 240 0.016
spindle midzone assembly GO:0051255 1 0.016
cell adhesion GO:0007155 329 0.016
nucleotide catabolic process GO:0009166 217 0.016
leukocyte differentiation GO:0002521 342 0.016
stem cell differentiation GO:0048863 268 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
positive regulation of protein modification process GO:0031401 299 0.016
gland development GO:0048732 330 0.016
mapk cascade GO:0000165 281 0.016
muscle cell differentiation GO:0042692 261 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
mitotic sister chromatid separation GO:0051306 9 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of intracellular protein transport GO:0033157 82 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
peptidyl threonine modification GO:0018210 31 0.015
protein dna complex subunit organization GO:0071824 28 0.015
Yeast
peptidyl threonine phosphorylation GO:0018107 31 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
cilium morphogenesis GO:0060271 102 0.015
positive regulation of chromosome segregation GO:0051984 4 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
response to light stimulus GO:0009416 135 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
regulation of cell migration GO:0030334 219 0.014
mitochondrion organization GO:0007005 134 0.014
regulation of response to wounding GO:1903034 189 0.014
cytokine production GO:0001816 319 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
spindle organization GO:0007051 28 0.014
anatomical structure homeostasis GO:0060249 145 0.014
regulation of proteolysis GO:0030162 164 0.014
stem cell development GO:0048864 219 0.014
positive regulation of transferase activity GO:0051347 167 0.014
dna geometric change GO:0032392 7 0.014
Fly
atp metabolic process GO:0046034 75 0.014
negative regulation of immune system process GO:0002683 209 0.014
neural tube development GO:0021915 160 0.014
oogenesis GO:0048477 56 0.014
negative regulation of protein modification process GO:0031400 163 0.014
protein localization to chromatin GO:0071168 3 0.014
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.014
stem cell maintenance GO:0019827 130 0.014
dna biosynthetic process GO:0071897 22 0.013
Fly
signal transduction by p53 class mediator GO:0072331 51 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
regulation of intracellular transport GO:0032386 159 0.013
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.013
cell growth GO:0016049 130 0.013
dna replication independent nucleosome assembly GO:0006336 1 0.013
regulation of mapk cascade GO:0043408 248 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
cell aging GO:0007569 35 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
oocyte differentiation GO:0009994 35 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
dna catabolic process exonucleolytic GO:0000738 3 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
b cell activation GO:0042113 161 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
lymphocyte apoptotic process GO:0070227 54 0.013
developmental maturation GO:0021700 193 0.013
regulation of protein stability GO:0031647 52 0.013
digestive system development GO:0055123 200 0.013
regulation of dna dependent dna replication GO:0090329 8 0.013
placenta development GO:0001890 140 0.013
cellularization GO:0007349 1 0.012
regulation of cell activation GO:0050865 289 0.012
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.012
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
cellular response to radiation GO:0071478 28 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
negative regulation of nuclear division GO:0051784 19 0.012
astral microtubule organization GO:0030953 3 0.012
rho protein signal transduction GO:0007266 32 0.012
response to inorganic substance GO:0010035 96 0.012
positive regulation of cell death GO:0010942 224 0.012
t cell differentiation GO:0030217 174 0.012
negative regulation of leukocyte apoptotic process GO:2000107 31 0.012
protein autophosphorylation GO:0046777 61 0.012
neural tube formation GO:0001841 108 0.012
positive regulation of oocyte development GO:0060282 4 0.012
extracellular structure organization GO:0043062 148 0.012
adaptive immune response GO:0002250 155 0.012
regulation of protein processing GO:0070613 96 0.012
response to radiation GO:0009314 165 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
striated muscle cell development GO:0055002 125 0.012
molting cycle GO:0042303 90 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
cellular chemical homeostasis GO:0055082 215 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
Fly
g0 to g1 transition GO:0045023 3 0.011
sister chromatid cohesion GO:0007062 12 0.011
wnt signaling pathway GO:0016055 188 0.011
positive regulation of t cell activation GO:0050870 101 0.011
divalent inorganic cation transport GO:0072511 178 0.011
photoreceptor cell differentiation GO:0046530 52 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
retina development in camera type eye GO:0060041 119 0.011
regulation of hydrolase activity GO:0051336 246 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.011
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
centrosome duplication GO:0051298 16 0.011
g2 dna damage checkpoint GO:0031572 8 0.011
Fly
cellular ion homeostasis GO:0006873 165 0.011
histone phosphorylation GO:0016572 9 0.011
regulation of secretion GO:0051046 274 0.011
microtubule nucleation GO:0007020 2 0.011
nucleus organization GO:0006997 45 0.011
regulation of transferase activity GO:0051338 263 0.011
oxidation reduction process GO:0055114 342 0.011
leukocyte proliferation GO:0070661 172 0.011
positive regulation of cytokine production GO:0001819 174 0.011
locomotory behavior GO:0007626 195 0.011
positive regulation of nervous system development GO:0051962 221 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
nuclear import GO:0051170 95 0.011
muscle cell development GO:0055001 133 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
regulation of cell cycle checkpoint GO:1901976 9 0.010
negative regulation of cytoskeleton organization GO:0051494 36 0.010
calcium ion transport GO:0006816 159 0.010
regulation of defense response GO:0031347 233 0.010
nucleoside catabolic process GO:0009164 206 0.010
multi multicellular organism process GO:0044706 109 0.010
leukocyte apoptotic process GO:0071887 71 0.010
transmembrane transport GO:0055085 412 0.010
establishment of spindle orientation GO:0051294 15 0.010
actin filament based movement GO:0030048 23 0.010
sensory perception GO:0007600 245 0.010
spindle assembly GO:0051225 13 0.010
spermatid development GO:0007286 108 0.010
intracellular mrna localization GO:0008298 4 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.010

Cdc45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.022
disease of anatomical entity DOID:7 0 0.022
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.014