Mus musculus

55 known processes

Cdk6

cyclin-dependent kinase 6

(Aliases: Crk2,AI504062,5830411I20)

Cdk6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to endoplasmic reticulum stress GO:0034976 53 0.946
positive regulation of mammary gland epithelial cell proliferation GO:0033601 5 0.836
lactation GO:0007595 25 0.833
t cell proliferation GO:0042098 120 0.796
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.781
mitochondrion organization GO:0007005 134 0.780
Fly
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 6 0.739
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.719
regulation of body fluid levels GO:0050878 162 0.697
response to unfolded protein GO:0006986 21 0.665
mammary gland lobule development GO:0061377 22 0.648
jak stat cascade GO:0007259 42 0.641
Fly
response to testosterone GO:0033574 3 0.634
cellular response to topologically incorrect protein GO:0035967 25 0.623
mammary gland epithelial cell proliferation GO:0033598 24 0.617
leukocyte proliferation GO:0070661 172 0.579
gland development GO:0048732 330 0.572
t cell activation GO:0042110 289 0.572
lymphocyte proliferation GO:0046651 164 0.497
mammary gland epithelium development GO:0061180 65 0.481
re entry into mitotic cell cycle GO:0000320 3 0.457
response to topologically incorrect protein GO:0035966 25 0.453
cell cycle g1 s phase transition GO:0044843 57 0.448
Worm
mammary gland alveolus development GO:0060749 22 0.433
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.431
Worm
body fluid secretion GO:0007589 53 0.426
male gamete generation GO:0048232 285 0.415
regulation of cell cycle g1 s phase transition GO:1902806 35 0.402
Worm
endoplasmic reticulum unfolded protein response GO:0030968 19 0.389
regulation of mitotic cell cycle GO:0007346 126 0.383
Worm
fat cell differentiation GO:0045444 160 0.376
response to organic cyclic compound GO:0014070 198 0.374
hepaticobiliary system development GO:0061008 67 0.373
er nucleus signaling pathway GO:0006984 27 0.367
liver development GO:0001889 66 0.359
negative regulation of cell cycle GO:0045786 123 0.351
Human
positive regulation of protein kinase activity GO:0045860 144 0.313
regulation of wnt signaling pathway GO:0030111 123 0.297
wnt signaling pathway GO:0016055 188 0.290
regulation of transferase activity GO:0051338 263 0.287
spermatogenesis GO:0007283 284 0.280
positive regulation of protein phosphorylation GO:0001934 242 0.279
epithelial cell proliferation GO:0050673 174 0.278
Human
regulation of kinase activity GO:0043549 249 0.274
leukocyte differentiation GO:0002521 342 0.268
positive regulation of epithelial cell proliferation GO:0050679 68 0.268
regulation of mitotic cell cycle phase transition GO:1901990 73 0.267
Worm
regulation of cell cycle process GO:0010564 160 0.264
Worm
canonical wnt signaling pathway GO:0060070 130 0.260
regulation of neuron differentiation GO:0045664 281 0.257
response to organonitrogen compound GO:0010243 246 0.256
response to peptide hormone GO:0043434 127 0.254
regulation of cell cycle GO:0051726 281 0.252
Human Mouse Worm
positive regulation of protein modification process GO:0031401 299 0.252
mitotic cell cycle process GO:1903047 159 0.251
Worm
g1 s transition of mitotic cell cycle GO:0000082 57 0.235
Worm
regulation of cellular ketone metabolic process GO:0010565 66 0.228
ovarian follicle development GO:0001541 40 0.222
positive regulation of kinase activity GO:0033674 155 0.222
regulation of protein kinase activity GO:0045859 232 0.220
regulation of protein serine threonine kinase activity GO:0071900 157 0.220
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.206
amine metabolic process GO:0009308 45 0.202
chromatin organization GO:0006325 206 0.202
positive regulation of cell cycle GO:0045787 92 0.201
Worm
regulation of cellular amine metabolic process GO:0033238 20 0.199
response to ethanol GO:0045471 18 0.194
response to alcohol GO:0097305 48 0.192
positive regulation of cell growth GO:0030307 33 0.189
response to organophosphorus GO:0046683 22 0.189
apoptotic signaling pathway GO:0097190 306 0.188
organelle fission GO:0048285 170 0.188
Worm
cellular amine metabolic process GO:0044106 44 0.178
development of primary female sexual characteristics GO:0046545 73 0.176
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.176
response to purine containing compound GO:0014074 28 0.163
regulation of epithelial cell proliferation GO:0050678 141 0.162
Human
cell growth GO:0016049 130 0.158
Fly
positive regulation of growth GO:0045927 104 0.154
cellular amino acid metabolic process GO:0006520 103 0.152
cellular ketone metabolic process GO:0042180 84 0.151
gonad development GO:0008406 141 0.151
Worm
negative regulation of wnt signaling pathway GO:0030178 73 0.147
dna metabolic process GO:0006259 303 0.147
cellular response to peptide hormone stimulus GO:0071375 92 0.146
response to steroid hormone GO:0048545 56 0.145
mitotic cell cycle GO:0000278 195 0.144
Worm Fly
female gonad development GO:0008585 71 0.143
regulation of cellular amino acid metabolic process GO:0006521 5 0.141
response to radiation GO:0009314 165 0.140
negative regulation of cell cycle arrest GO:0071157 1 0.137
cellular response to organonitrogen compound GO:0071417 145 0.136
ovulation cycle GO:0042698 59 0.132
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.129
development of primary sexual characteristics GO:0045137 143 0.128
Worm
positive regulation of transferase activity GO:0051347 167 0.127
rhythmic process GO:0048511 174 0.126
response to estrogen GO:0043627 24 0.125
camera type eye development GO:0043010 266 0.124
cellular response to peptide GO:1901653 92 0.123
endocytosis GO:0006897 168 0.122
regulation of cell growth GO:0001558 91 0.119
response to corticosterone GO:0051412 1 0.115
cellular response to dna damage stimulus GO:0006974 207 0.115
cellular response to gamma radiation GO:0071480 4 0.114
response to peptide GO:1901652 136 0.113
organ regeneration GO:0031100 2 0.111
positive regulation of cellular amine metabolic process GO:0033240 5 0.107
sensory organ morphogenesis GO:0090596 242 0.104
myeloid cell differentiation GO:0030099 233 0.104
Human
regulation of hydrolase activity GO:0051336 246 0.102
nuclear division GO:0000280 158 0.096
Worm
negative regulation of phosphorylation GO:0042326 166 0.095
regulation of cell cycle g2 m phase transition GO:1902749 10 0.095
mitotic g1 dna damage checkpoint GO:0031571 4 0.094
negative regulation of cellular amine metabolic process GO:0033239 1 0.092
response to camp GO:0051591 14 0.090
myeloid leukocyte differentiation GO:0002573 119 0.088
regulation of organelle organization GO:0033043 289 0.088
cellular response to insulin stimulus GO:0032869 78 0.087
cellular lipid metabolic process GO:0044255 323 0.087
peptidyl amino acid modification GO:0018193 336 0.086
connective tissue development GO:0061448 179 0.083
regulation of cellular catabolic process GO:0031329 242 0.082
regulation of lymphocyte activation GO:0051249 240 0.082
negative regulation of cell proliferation GO:0008285 296 0.082
Human
inflammatory response GO:0006954 244 0.081
epithelial tube morphogenesis GO:0060562 303 0.080
positive regulation of organelle organization GO:0010638 128 0.079
ribonucleotide metabolic process GO:0009259 291 0.078
regulation of cell activation GO:0050865 289 0.077
blood vessel morphogenesis GO:0048514 285 0.077
cell fate commitment GO:0045165 210 0.077
chromatin modification GO:0016568 187 0.077
nucleobase containing small molecule metabolic process GO:0055086 352 0.076
ribonucleoside metabolic process GO:0009119 245 0.074
negative regulation of phosphorus metabolic process GO:0010563 184 0.074
response to insulin GO:0032868 100 0.073
regulation of membrane potential GO:0042391 192 0.072
urogenital system development GO:0001655 261 0.071
muscle cell differentiation GO:0042692 261 0.070
response to x ray GO:0010165 11 0.070
response to iron ion GO:0010039 4 0.068
covalent chromatin modification GO:0016569 163 0.068
stem cell differentiation GO:0048863 268 0.067
notch signaling pathway GO:0007219 71 0.067
t cell differentiation GO:0030217 174 0.066
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.066
ras protein signal transduction GO:0007265 77 0.066
lymphocyte differentiation GO:0030098 242 0.065
cellular response to lipid GO:0071396 145 0.065
nucleotide metabolic process GO:0009117 332 0.064
axon guidance GO:0007411 141 0.064
regulation of leukocyte differentiation GO:1902105 159 0.062
regulation of cell cycle phase transition GO:1901987 77 0.062
Worm
small gtpase mediated signal transduction GO:0007264 97 0.060
transmembrane transport GO:0055085 412 0.060
negative regulation of immune system process GO:0002683 209 0.060
Human
positive regulation of apoptotic process GO:0043065 217 0.058
negative regulation of cellular protein metabolic process GO:0032269 247 0.058
morphogenesis of embryonic epithelium GO:0016331 159 0.057
positive regulation of lymphocyte activation GO:0051251 140 0.057
regulation of cellular component biogenesis GO:0044087 181 0.057
regulation of t cell activation GO:0050863 170 0.056
t cell differentiation in thymus GO:0033077 77 0.056
response to ketone GO:1901654 15 0.055
response to ionizing radiation GO:0010212 42 0.055
response to inorganic substance GO:0010035 96 0.054
respiratory tube development GO:0030323 167 0.054
response to uv GO:0009411 44 0.054
hematopoietic progenitor cell differentiation GO:0002244 143 0.054
nucleoside triphosphate metabolic process GO:0009141 230 0.054
negative regulation of intracellular signal transduction GO:1902532 167 0.053
striated muscle tissue development GO:0014706 293 0.053
heterocycle catabolic process GO:0046700 280 0.053
peptidyl tyrosine phosphorylation GO:0018108 143 0.053
cell cycle checkpoint GO:0000075 47 0.053
response to light stimulus GO:0009416 135 0.053
positive regulation of programmed cell death GO:0043068 218 0.052
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 5 0.052
negative regulation of phosphate metabolic process GO:0045936 184 0.050
negative regulation of molecular function GO:0044092 258 0.050
response to estradiol GO:0032355 12 0.049
purine nucleotide metabolic process GO:0006163 302 0.049
purine containing compound metabolic process GO:0072521 311 0.049
cellular response to growth factor stimulus GO:0071363 197 0.049
reactive oxygen species metabolic process GO:0072593 84 0.049
ribonucleoside catabolic process GO:0042454 206 0.049
ribonucleoside triphosphate metabolic process GO:0009199 220 0.049
ossification GO:0001503 216 0.049
Human
response to molecule of bacterial origin GO:0002237 143 0.048
mapk cascade GO:0000165 281 0.048
positive regulation of cell death GO:0010942 224 0.048
protein localization to organelle GO:0033365 185 0.048
positive regulation of leukocyte proliferation GO:0070665 73 0.048
negative regulation of protein modification process GO:0031400 163 0.047
gtp catabolic process GO:0006184 143 0.047
leydig cell differentiation GO:0033327 10 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.046
cellular response to cytokine stimulus GO:0071345 189 0.046
response to uv a GO:0070141 1 0.046
peptidyl tyrosine modification GO:0018212 145 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.045
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.045
nuclear transport GO:0051169 139 0.045
regulation of t cell proliferation GO:0042129 92 0.045
response to mineralocorticoid GO:0051385 1 0.044
positive regulation of leukocyte differentiation GO:1902107 86 0.044
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.043
germ cell development GO:0007281 185 0.043
neuron projection guidance GO:0097485 141 0.043
renal system development GO:0072001 225 0.043
positive regulation of peptidase activity GO:0010952 49 0.043
cell type specific apoptotic process GO:0097285 268 0.042
response to oxygen levels GO:0070482 62 0.042
stem cell development GO:0048864 219 0.042
nucleoside phosphate metabolic process GO:0006753 338 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
regulation of cytokine production GO:0001817 266 0.041
intrinsic apoptotic signaling pathway GO:0097193 132 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.041
negative regulation of cell cycle process GO:0010948 69 0.041
negative regulation of protein phosphorylation GO:0001933 126 0.041
epithelial cell development GO:0002064 159 0.040
Human
neuron apoptotic process GO:0051402 142 0.040
skeletal system development GO:0001501 356 0.040
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.040
regulation of cell adhesion GO:0030155 154 0.039
Human
nucleoside metabolic process GO:0009116 246 0.039
regionalization GO:0003002 337 0.039
Fly
protein processing GO:0016485 163 0.039
sensory perception GO:0007600 245 0.039
immune effector process GO:0002252 321 0.039
regulation of leukocyte proliferation GO:0070663 121 0.038
regulation of apoptotic signaling pathway GO:2001233 197 0.038
release of cytochrome c from mitochondria GO:0001836 23 0.038
b cell activation GO:0042113 161 0.038
regulation of cellular response to stress GO:0080135 159 0.038
Human
regulation of lymphocyte proliferation GO:0050670 117 0.038
response to transforming growth factor beta GO:0071559 88 0.038
purine nucleoside metabolic process GO:0042278 241 0.038
cellular homeostasis GO:0019725 240 0.038
response to hypoxia GO:0001666 58 0.037
histone modification GO:0016570 159 0.037
regulation of mapk cascade GO:0043408 248 0.037
response to calcium ion GO:0051592 20 0.037
cellular response to hormone stimulus GO:0032870 150 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
regulation of peptidase activity GO:0052547 96 0.037
action potential GO:0001508 78 0.037
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
negative regulation of protein metabolic process GO:0051248 282 0.036
morphogenesis of a branching epithelium GO:0061138 193 0.036
rho protein signal transduction GO:0007266 32 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
cell cycle g2 m phase transition GO:0044839 20 0.036
response to acid chemical GO:0001101 111 0.035
positive regulation of cell activation GO:0050867 158 0.035
membrane organization GO:0061024 245 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.035
methylation GO:0032259 134 0.035
adult behavior GO:0030534 135 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.035
regulation of purine nucleotide metabolic process GO:1900542 169 0.034
dendrite development GO:0016358 115 0.034
compound eye development GO:0048749 1 0.034
regulation of response to wounding GO:1903034 189 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
regulation of myeloid leukocyte differentiation GO:0002761 58 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.033
multicellular organismal signaling GO:0035637 91 0.033
cytokine production GO:0001816 319 0.033
wound healing GO:0042060 157 0.033
male sex differentiation GO:0046661 109 0.032
regulation of myeloid cell differentiation GO:0045637 96 0.032
Human
carbohydrate metabolic process GO:0005975 230 0.032
limb development GO:0060173 166 0.032
negative regulation of mitotic cell cycle GO:0045930 58 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
chemotaxis GO:0006935 247 0.031
anion transport GO:0006820 177 0.031
positive regulation of proteolysis GO:0045862 85 0.031
meiotic cell cycle GO:0051321 122 0.031
Worm
response to lipopolysaccharide GO:0032496 128 0.031
negative regulation of cell cycle phase transition GO:1901988 48 0.031
angiogenesis GO:0001525 201 0.031
homeostasis of number of cells GO:0048872 210 0.031
Human
striated muscle cell development GO:0055002 125 0.031
regulation of ossification GO:0030278 112 0.031
Human
negative regulation of cell development GO:0010721 169 0.031
appendage morphogenesis GO:0035107 149 0.031
nucleoside catabolic process GO:0009164 206 0.031
negative regulation of leukocyte differentiation GO:1902106 51 0.030
monocarboxylic acid metabolic process GO:0032787 191 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
tube formation GO:0035148 140 0.030
regulation of endopeptidase activity GO:0052548 89 0.030
organophosphate catabolic process GO:0046434 232 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.030
multi multicellular organism process GO:0044706 109 0.030
mitotic cell cycle checkpoint GO:0007093 31 0.030
regulation of inflammatory response GO:0050727 147 0.030
neuron death GO:0070997 154 0.029
maintenance of location GO:0051235 89 0.029
multicellular organismal homeostasis GO:0048871 164 0.029
embryonic epithelial tube formation GO:0001838 130 0.029
positive regulation of cell cycle process GO:0090068 61 0.029
Worm
kidney development GO:0001822 213 0.029
microtubule cytoskeleton organization GO:0000226 157 0.029
regulation of fibroblast proliferation GO:0048145 34 0.029
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
positive regulation of lymphocyte proliferation GO:0050671 70 0.029
positive regulation of t cell activation GO:0050870 101 0.029
lipid biosynthetic process GO:0008610 179 0.029
adaptive immune response GO:0002250 155 0.029
regulation of chromatin modification GO:1903308 57 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
single organismal cell cell adhesion GO:0016337 131 0.028
neuronal action potential GO:0019228 54 0.028
bmp signaling pathway GO:0030509 93 0.028
embryonic limb morphogenesis GO:0030326 126 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
protein catabolic process GO:0030163 221 0.028
positive regulation of t cell proliferation GO:0042102 52 0.027
nucleotide catabolic process GO:0009166 217 0.027
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.027
positive regulation of mitotic cell cycle GO:0045931 41 0.027
Worm
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
meiotic nuclear division GO:0007126 115 0.027
Worm
regeneration GO:0031099 38 0.027
retina development in camera type eye GO:0060041 119 0.027
regulation of chromosome organization GO:0033044 83 0.027
muscle cell development GO:0055001 133 0.026
organophosphate biosynthetic process GO:0090407 122 0.026
apoptotic mitochondrial changes GO:0008637 48 0.026
signal transduction by p53 class mediator GO:0072331 51 0.026
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.026
cellular response to radiation GO:0071478 28 0.026
positive regulation of cell development GO:0010720 237 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.026
digestive tract morphogenesis GO:0048546 147 0.026
fertilization GO:0009566 127 0.026
digestive tract development GO:0048565 190 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
b cell differentiation GO:0030183 78 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.025
actin cytoskeleton organization GO:0030036 220 0.025
anatomical structure homeostasis GO:0060249 145 0.025
regulation of neuron death GO:1901214 134 0.025
positive regulation of endopeptidase activity GO:0010950 43 0.025
gene silencing GO:0016458 38 0.025
mitotic nuclear division GO:0007067 48 0.025
Worm
regulation of chromatin silencing GO:0031935 2 0.025
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
circulatory system process GO:0003013 197 0.024
positive regulation of myeloid cell differentiation GO:0045639 43 0.024
cellular response to antibiotic GO:0071236 4 0.024
regulation of neuron projection development GO:0010975 169 0.024
embryonic organ morphogenesis GO:0048562 276 0.024
positive regulation of cellular catabolic process GO:0031331 148 0.024
placenta development GO:0001890 140 0.024
skeletal system morphogenesis GO:0048705 203 0.024
regulation of striated muscle cell differentiation GO:0051153 81 0.024
regulation of secretion by cell GO:1903530 249 0.024
cytokine mediated signaling pathway GO:0019221 115 0.024
protein localization to nucleus GO:0034504 121 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.024
lung development GO:0030324 164 0.023
immune response activating signal transduction GO:0002757 116 0.023
lymphocyte homeostasis GO:0002260 64 0.023
osteoclast differentiation GO:0030316 62 0.023
regulation of osteoblast differentiation GO:0045667 67 0.023
Human
glial cell differentiation GO:0010001 131 0.023
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.023
purine containing compound catabolic process GO:0072523 213 0.023
modification dependent macromolecule catabolic process GO:0043632 133 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
oxidation reduction process GO:0055114 342 0.023
regulation of proteolysis GO:0030162 164 0.023
fibroblast proliferation GO:0048144 35 0.023
Human
cellular response to lipopolysaccharide GO:0071222 77 0.023
negative regulation of growth GO:0045926 99 0.023
dna repair GO:0006281 107 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
organic anion transport GO:0015711 137 0.022
cell junction organization GO:0034330 77 0.022
response to extracellular stimulus GO:0009991 127 0.022
divalent inorganic cation transport GO:0072511 178 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
midgut development GO:0007494 4 0.022
locomotory behavior GO:0007626 195 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
natural killer cell activation GO:0030101 44 0.022
cell aging GO:0007569 35 0.022
Human
organelle assembly GO:0070925 177 0.022
hindbrain development GO:0030902 128 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
protein targeting GO:0006605 143 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
neuroblast fate determination GO:0007400 1 0.021
cardiocyte differentiation GO:0035051 87 0.021
negative regulation of chromatin silencing GO:0031936 1 0.021
positive regulation of protein oligomerization GO:0032461 4 0.021
cellular protein catabolic process GO:0044257 155 0.021
negative regulation of nervous system development GO:0051961 156 0.021
erythrocyte differentiation GO:0030218 88 0.021
Human
glucose metabolic process GO:0006006 92 0.021
response to decreased oxygen levels GO:0036293 59 0.021
response to nutrient levels GO:0031667 109 0.021
response to growth factor GO:0070848 198 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
ion transmembrane transport GO:0034220 361 0.021
cellular response to biotic stimulus GO:0071216 92 0.021
axonogenesis GO:0007409 274 0.021
negative regulation of myeloid cell differentiation GO:0045638 38 0.021
Human
male gonad development GO:0008584 88 0.021
energy derivation by oxidation of organic compounds GO:0015980 77 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
negative regulation of fat cell differentiation GO:0045599 36 0.021
lateral inhibition GO:0046331 1 0.021
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.021
metal ion homeostasis GO:0055065 189 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
stomach neuroendocrine cell differentiation GO:0061102 2 0.020
protein maturation GO:0051604 176 0.020
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
regulation of cell migration GO:0030334 219 0.020
regulation of system process GO:0044057 200 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
negative regulation of response to wounding GO:1903035 77 0.020
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
sulfur compound metabolic process GO:0006790 100 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
macromolecule methylation GO:0043414 120 0.020
gliogenesis GO:0042063 141 0.020
Human
transmission of nerve impulse GO:0019226 76 0.020
positive regulation of neuron apoptotic process GO:0043525 25 0.020
mesonephric tubule development GO:0072164 94 0.020
cell cycle arrest GO:0007050 37 0.020
negative regulation of dna replication GO:0008156 4 0.020
osteoblast development GO:0002076 17 0.020
cognition GO:0050890 149 0.019
cell division GO:0051301 120 0.019
appendage development GO:0048736 166 0.019
multicellular organism growth GO:0035264 161 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
oocyte construction GO:0007308 2 0.019
positive regulation of glial cell proliferation GO:0060252 4 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
cellular ion homeostasis GO:0006873 165 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
guanosine containing compound catabolic process GO:1901069 144 0.019
regulation of multi organism process GO:0043900 111 0.019
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.019
regulation of defense response GO:0031347 233 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
regulation of cell motility GO:2000145 236 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
t cell anergy GO:0002870 4 0.019
regulation of organ morphogenesis GO:2000027 144 0.019
photoreceptor cell differentiation GO:0046530 52 0.018
regulation of t cell anergy GO:0002667 4 0.018
regulation of t cell differentiation GO:0045580 83 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
negative regulation of mapk cascade GO:0043409 65 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
brown fat cell differentiation GO:0050873 36 0.018
response to corticosteroid GO:0031960 20 0.018
skeletal muscle cell differentiation GO:0035914 66 0.018

Cdk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system cancer DOID:0060083 0 0.262
hematologic cancer DOID:2531 0 0.262
cancer DOID:162 0 0.262
disease of cellular proliferation DOID:14566 0 0.262
organ system cancer DOID:0050686 0 0.262
large intestine cancer DOID:5672 0 0.087
gastrointestinal system cancer DOID:3119 0 0.087
intestinal cancer DOID:10155 0 0.087
colon cancer DOID:219 0 0.064
colorectal cancer DOID:9256 0 0.064
colon carcinoma DOID:1520 0 0.042
bone marrow cancer DOID:4960 0 0.024
immune system disease DOID:2914 0 0.019
disease of anatomical entity DOID:7 0 0.019