|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.961
|
Human |
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.919
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.904
|
Human |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.892
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.883
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.784
|
Human |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.760
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.691
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.688
|
Human |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.687
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.674
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.647
|
Human |
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.622
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.616
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.613
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.581
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.567
|
Human |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.560
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.558
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.555
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.552
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.529
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.509
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.476
|
Human |
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.464
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.464
|
Human |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.462
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.461
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.453
|
Human |
|
|
cellular response to antibiotic
|
GO:0071236 |
4 |
0.446
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.440
|
Human |
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.423
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.416
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.410
|
Mouse |
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.405
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.403
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.395
|
Human |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.386
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.384
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.384
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.376
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.365
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.364
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.358
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.358
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.347
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.327
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.321
|
Human |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.318
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.317
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.308
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.301
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.299
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.297
|
Human |
|
|
gland development
|
GO:0048732 |
330 |
0.296
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.294
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
7 |
0.285
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.279
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.275
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.272
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.269
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.266
|
Human |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.265
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.262
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.244
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.240
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.238
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.236
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.234
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.228
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
4 |
0.223
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.222
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.220
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.220
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.216
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.215
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.201
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.200
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.198
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.195
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.194
|
Mouse |
|
|
rrna transcription
|
GO:0009303 |
9 |
0.194
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.193
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.190
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.189
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.185
|
Mouse |
|
|
protein maturation
|
GO:0051604 |
176 |
0.184
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.182
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.180
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.180
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.178
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.177
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.175
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.173
|
|
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.169
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.168
|
Mouse |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.167
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.166
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.166
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.166
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.164
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.164
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.164
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.162
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.160
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.159
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.159
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.157
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.157
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.155
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.155
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.154
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.153
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
22 |
0.153
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.153
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.152
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.151
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.150
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.150
|
|
|
|
negative regulation of mammary gland epithelial cell proliferation
|
GO:0033600 |
3 |
0.148
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.144
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.144
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
18 |
0.141
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.139
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.136
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.136
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.135
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
165 |
0.135
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
3 |
0.135
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.134
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.134
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.134
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.133
|
Human |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.131
|
Mouse |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.131
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.128
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.125
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.124
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.121
|
|
|
|
metaphase plate congression
|
GO:0051310 |
2 |
0.121
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.121
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.120
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.120
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
10 |
0.119
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.119
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.118
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.118
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.117
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.116
|
Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.116
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.115
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.115
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.115
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.114
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.114
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.114
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.112
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.112
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.112
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.111
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.107
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.106
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.106
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.106
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
14 |
0.105
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.104
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.103
|
|
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.102
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.101
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.100
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
22 |
0.100
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.099
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.099
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.099
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.098
|
Mouse |
|
|
embryonic axis specification
|
GO:0000578 |
30 |
0.098
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.096
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.096
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.096
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.096
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.095
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.094
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.094
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.094
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.093
|
|
|
|
optic placode formation
|
GO:0001743 |
2 |
0.093
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.091
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.091
|
|
|
|
optic placode formation involved in camera type eye formation
|
GO:0046619 |
2 |
0.090
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.090
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.090
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.088
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.088
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.088
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.088
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.087
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.087
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.087
|
Mouse |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.086
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.086
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.085
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.085
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.085
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.083
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.083
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.083
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.082
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.082
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.081
|
Human |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.079
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.079
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.078
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.077
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.076
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.076
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.076
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
3 |
0.075
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.075
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.075
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.075
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.074
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.074
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
26 |
0.074
|
Mouse |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.073
|
|
|
|
positive regulation of muscle cell apoptotic process
|
GO:0010661 |
6 |
0.072
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.072
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.072
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.071
|
|
|
|
organ induction
|
GO:0001759 |
21 |
0.071
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.071
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.070
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.070
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.070
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.070
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.070
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.069
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.068
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.067
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
3 |
0.066
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.066
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.066
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.065
|
|
|
|
regulation of cohesin localization to chromatin
|
GO:0071922 |
1 |
0.065
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage
|
GO:1902229 |
14 |
0.065
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.065
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.065
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.065
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.065
|
|
|
|
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
|
GO:0060527 |
7 |
0.065
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.064
|
Mouse |
|
|
positive regulation of leukocyte apoptotic process
|
GO:2000108 |
21 |
0.064
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.064
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.064
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.064
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
3 |
0.063
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.063
|
|
|
|
positive regulation of microtubule polymerization
|
GO:0031116 |
3 |
0.063
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.063
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.062
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.062
|
Mouse |
|
|
response to vitamin d
|
GO:0033280 |
3 |
0.062
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.062
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.062
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.062
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.062
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.061
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.061
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
3 |
0.061
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.061
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.061
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.060
|
|
|
|
regulation of mammary gland involution
|
GO:1903519 |
4 |
0.060
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.059
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.059
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.059
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.059
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
18 |
0.058
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.058
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
20 |
0.058
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.058
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.058
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.058
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.057
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.057
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.057
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.057
|
|
|
|
cohesin localization to chromatin
|
GO:0071921 |
1 |
0.057
|
|
|
|
prostate gland epithelium morphogenesis
|
GO:0060740 |
31 |
0.057
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.057
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.057
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.056
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.056
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.056
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.056
|
|
|
|
response to x ray
|
GO:0010165 |
11 |
0.055
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.055
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.055
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.055
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.054
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.054
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.054
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.054
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.054
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
3 |
0.053
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.053
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.052
|
|
|
|
positive regulation of macrophage apoptotic process
|
GO:2000111 |
3 |
0.052
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.052
|
|
|
|
regulation of mammary gland epithelial cell proliferation
|
GO:0033599 |
12 |
0.052
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.051
|
Mouse |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.051
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.050
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.050
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.050
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.050
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.049
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.049
|
|
|
|
negative regulation of fibroblast migration
|
GO:0010764 |
2 |
0.049
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.049
|
Mouse |
|
|
cellular response to toxic substance
|
GO:0097237 |
7 |
0.049
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.049
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.049
|
|
|
|
response to nutrient
|
GO:0007584 |
12 |
0.048
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.048
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.048
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.048
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.048
|
|
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.048
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.048
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.048
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.047
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.047
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.047
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.047
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
3 |
0.047
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
35 |
0.046
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.046
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.046
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.046
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.046
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.045
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.045
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.045
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.045
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.045
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
13 |
0.045
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.045
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.045
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.045
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.045
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.045
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.044
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.044
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.044
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
24 |
0.044
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.044
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.044
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.044
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.044
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
3 |
0.043
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.043
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.043
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.043
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.043
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.043
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.043
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.043
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.042
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.042
|
|
|
|
regulation of organ formation
|
GO:0003156 |
34 |
0.042
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.042
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.042
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.042
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.042
|
|
|
|
negative regulation of tor signaling
|
GO:0032007 |
13 |
0.042
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.041
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
47 |
0.041
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.041
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.041
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
20 |
0.041
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.041
|
|
|
|
stem cell division
|
GO:0017145 |
30 |
0.041
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.040
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.040
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
4 |
0.040
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.040
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.040
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.040
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.039
|
|
|
|
regulation of protein import into nucleus translocation
|
GO:0033158 |
2 |
0.039
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.039
|
Mouse |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.039
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.039
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.039
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.038
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.038
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.038
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.038
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.038
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.038
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.038
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.038
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.037
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.037
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.037
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.037
|
|
|
|
regulation of spindle organization
|
GO:0090224 |
2 |
0.037
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.036
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.036
|
|
|
|
dopamine uptake
|
GO:0090494 |
4 |
0.036
|
|
|
|
regulation of phosphoprotein phosphatase activity
|
GO:0043666 |
3 |
0.036
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.036
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.036
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.036
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.036
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.035
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.035
|
|
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.035
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.035
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.035
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.035
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.035
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.035
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.035
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.035
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
9 |
0.034
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.034
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
3 |
0.034
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.034
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
3 |
0.034
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.034
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.033
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.033
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.033
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.033
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.033
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.033
|
|
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
32 |
0.033
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.033
|
|
|
|
prostate glandular acinus morphogenesis
|
GO:0060526 |
7 |
0.033
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.033
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.032
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.032
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.032
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.032
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.032
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.032
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.032
|
|
|
|
positive regulation of mitotic metaphase anaphase transition
|
GO:0045842 |
2 |
0.032
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.032
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.031
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
4 |
0.031
|
|
|
|
trophectodermal cellular morphogenesis
|
GO:0001831 |
3 |
0.031
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.031
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.031
|
|
|
|
protein localization to chromatin
|
GO:0071168 |
3 |
0.030
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.030
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.030
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.030
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.030
|
Mouse |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.030
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
7 |
0.030
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.029
|
|
|
|
regulation of t cell differentiation in thymus
|
GO:0033081 |
24 |
0.029
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.029
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.029
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.029
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
3 |
0.029
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.029
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.029
|
|
|
|
regulation of mitotic spindle organization
|
GO:0060236 |
2 |
0.029
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.029
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.028
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.028
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.028
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.028
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.028
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
6 |
0.028
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.028
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.028
|
Mouse |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.028
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.028
|
|
|
|
regulation of catecholamine uptake involved in synaptic transmission
|
GO:0051940 |
2 |
0.028
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.027
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.027
|
|
