Mus musculus

2 known processes

Ces1e

carboxylesterase 1E

(Aliases: Es22,Eg,egasyn,Es-22)

Ces1e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
short chain fatty acid catabolic process GO:0019626 2 0.868
Mouse
cellular lipid metabolic process GO:0044255 323 0.474
Mouse
fatty acid metabolic process GO:0006631 121 0.335
Mouse
oxidation reduction process GO:0055114 342 0.294
establishment of blood nerve barrier GO:0008065 3 0.269
Fly
vitamin d3 metabolic process GO:0070640 3 0.179
female meiosis chromosome segregation GO:0016321 1 0.175
Fly
monocarboxylic acid metabolic process GO:0032787 191 0.170
Mouse
short chain fatty acid metabolic process GO:0046459 6 0.164
Mouse
carbohydrate metabolic process GO:0005975 230 0.163
organic acid catabolic process GO:0016054 51 0.162
Mouse
cellular lipid catabolic process GO:0044242 52 0.153
Mouse
lipid biosynthetic process GO:0008610 179 0.148
cellular amino acid metabolic process GO:0006520 103 0.121
carboxylic acid catabolic process GO:0046395 51 0.100
Mouse
vitamin d biosynthetic process GO:0042368 3 0.099
cellular ketone metabolic process GO:0042180 84 0.098
calcitriol biosynthetic process from calciol GO:0036378 3 0.096
sulfur compound metabolic process GO:0006790 100 0.094
acetylcholine catabolic process GO:0006581 1 0.093
Mouse
naphthalene metabolic process GO:0018931 1 0.092
naphthalene containing compound metabolic process GO:0090420 1 0.092
cofactor metabolic process GO:0051186 80 0.089
small molecule biosynthetic process GO:0044283 132 0.084
cellular alcohol biosynthetic process GO:0044108 3 0.084
monosaccharide metabolic process GO:0005996 106 0.084
xenobiotic catabolic process GO:0042178 1 0.081
small molecule catabolic process GO:0044282 71 0.081
Mouse
monocarboxylic acid catabolic process GO:0072329 27 0.077
Mouse
cellular alcohol metabolic process GO:0044107 3 0.075
regulation of cellular ketone metabolic process GO:0010565 66 0.074
fatty acid catabolic process GO:0009062 25 0.073
Mouse
nitrogen compound transport GO:0071705 271 0.072
peptide metabolic process GO:0006518 46 0.065
cellular homeostasis GO:0019725 240 0.063
regulation of hormone levels GO:0010817 211 0.063
cellular response to cadmium ion GO:0071276 3 0.061
glutathione metabolic process GO:0006749 16 0.060
cellular response to lipid GO:0071396 145 0.059
cellular amide metabolic process GO:0043603 58 0.059
organic acid biosynthetic process GO:0016053 86 0.058
transmembrane transport GO:0055085 412 0.058
cell adhesion GO:0007155 329 0.058
Fly
response to testosterone GO:0033574 3 0.057
response to organic cyclic compound GO:0014070 198 0.056
fat soluble vitamin biosynthetic process GO:0042362 4 0.055
sulfate assimilation GO:0000103 3 0.054
cellular amine metabolic process GO:0044106 44 0.051
organic hydroxy compound metabolic process GO:1901615 203 0.051
drug metabolic process GO:0017144 4 0.050
cellular modified amino acid metabolic process GO:0006575 63 0.050
unsaturated fatty acid metabolic process GO:0033559 31 0.050
organonitrogen compound catabolic process GO:1901565 264 0.050
Mouse
regulation of secretion GO:0051046 274 0.050
macromolecule glycosylation GO:0043413 55 0.049
cation transport GO:0006812 399 0.049
glucuronate metabolic process GO:0019585 2 0.049
icosanoid metabolic process GO:0006690 33 0.048
response to organonitrogen compound GO:0010243 246 0.048
lipid catabolic process GO:0016042 69 0.048
Mouse
terpenoid metabolic process GO:0006721 25 0.046
fatty acid derivative metabolic process GO:1901568 33 0.046
glycoprotein metabolic process GO:0009100 116 0.046
cation transmembrane transport GO:0098655 266 0.045
male gamete generation GO:0048232 285 0.042
Fly
ion transmembrane transport GO:0034220 361 0.040
spermatogenesis GO:0007283 284 0.040
Fly
amine metabolic process GO:0009308 45 0.039
meiotic nuclear division GO:0007126 115 0.039
Fly
response to acid chemical GO:0001101 111 0.038
protein glycosylation GO:0006486 55 0.038
glycosylation GO:0070085 62 0.038
protein maturation GO:0051604 176 0.038
hormone metabolic process GO:0042445 86 0.037
secondary alcohol metabolic process GO:1902652 3 0.035
amide transport GO:0042886 138 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
steroid metabolic process GO:0008202 119 0.034
response to inorganic substance GO:0010035 96 0.034
retinoic acid metabolic process GO:0042573 12 0.033
meiotic cell cycle process GO:1903046 77 0.032
Fly
energy derivation by oxidation of organic compounds GO:0015980 77 0.031
isoprenoid metabolic process GO:0006720 29 0.031
diterpenoid metabolic process GO:0016101 24 0.031
diacylglycerol biosynthetic process GO:0006651 2 0.031
response to phenylpropanoid GO:0080184 22 0.031
epithelial cell development GO:0002064 159 0.031
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
reactive oxygen species metabolic process GO:0072593 84 0.030
regulation of kinase activity GO:0043549 249 0.030
hexose metabolic process GO:0019318 98 0.030
carboxylic acid biosynthetic process GO:0046394 86 0.030
nuclear division GO:0000280 158 0.029
Fly
aromatic compound catabolic process GO:0019439 286 0.029
purine containing compound metabolic process GO:0072521 311 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
camera type eye development GO:0043010 266 0.028
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.028
hormone secretion GO:0046879 128 0.028
alcohol biosynthetic process GO:0046165 43 0.027
regulation of secretion by cell GO:1903530 249 0.027
glycerolipid metabolic process GO:0046486 122 0.027
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
uronic acid metabolic process GO:0006063 2 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
regulation of lipid metabolic process GO:0019216 118 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
drug catabolic process GO:0042737 2 0.026
cellular response to testosterone stimulus GO:0071394 1 0.026
macromolecule catabolic process GO:0009057 281 0.026
response to nutrient levels GO:0031667 109 0.025
benzene containing compound metabolic process GO:0042537 5 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
multicellular organismal signaling GO:0035637 91 0.025
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.024
leukocyte differentiation GO:0002521 342 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
blood circulation GO:0008015 195 0.024
glycoprotein biosynthetic process GO:0009101 89 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
chromosome segregation GO:0007059 48 0.024
Fly
heterocycle catabolic process GO:0046700 280 0.024
regulation of cellular response to stress GO:0080135 159 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
peptide transport GO:0015833 133 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
mapk cascade GO:0000165 281 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
organic hydroxy compound biosynthetic process GO:1901617 77 0.022
sphingolipid catabolic process GO:0030149 7 0.022
Mouse
regulation of cellular catabolic process GO:0031329 242 0.022
skeletal system development GO:0001501 356 0.022
regulation of neurotransmitter levels GO:0001505 87 0.022
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.022
nucleotide metabolic process GO:0009117 332 0.022
inorganic cation transmembrane transport GO:0098662 207 0.021
response to extracellular stimulus GO:0009991 127 0.021
cellular chemical homeostasis GO:0055082 215 0.021
cellular carbohydrate metabolic process GO:0044262 119 0.021
regulation of anatomical structure size GO:0090066 178 0.021
Fly
retinoid metabolic process GO:0001523 24 0.021
regulation of transferase activity GO:0051338 263 0.021
cell junction assembly GO:0034329 52 0.021
Fly
cellular response to molecule of bacterial origin GO:0071219 83 0.021
carbohydrate homeostasis GO:0033500 128 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
long chain fatty acid import GO:0044539 2 0.021
ethanol metabolic process GO:0006067 3 0.020
glucose homeostasis GO:0042593 128 0.020
positive regulation of plasminogen activation GO:0010756 2 0.020
cellular response to starvation GO:0009267 57 0.020
maintenance of location GO:0051235 89 0.020
response to oxidative stress GO:0006979 123 0.020
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.020
regulation of ion transport GO:0043269 215 0.020
regulation of blood pressure GO:0008217 93 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
progesterone metabolic process GO:0042448 4 0.019
oxidative demethylation GO:0070989 1 0.019
organelle fission GO:0048285 170 0.019
Fly
negative regulation of molecular function GO:0044092 258 0.019
toxin catabolic process GO:0009407 1 0.019
alcohol metabolic process GO:0006066 116 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.018
multi multicellular organism process GO:0044706 109 0.018
glucose metabolic process GO:0006006 92 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
ceramide catabolic process GO:0046514 7 0.018
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
porphyrin containing compound metabolic process GO:0006778 22 0.018
regulation of hormone secretion GO:0046883 88 0.018
insulin secretion GO:0030073 89 0.018
cellular response to biotic stimulus GO:0071216 92 0.018
peptide secretion GO:0002790 114 0.018
response to reactive oxygen species GO:0000302 56 0.018
organophosphate catabolic process GO:0046434 232 0.017
response to lipopolysaccharide GO:0032496 128 0.017
fat soluble vitamin metabolic process GO:0006775 11 0.017
cell junction organization GO:0034330 77 0.017
Fly
cellular response to inorganic substance GO:0071241 37 0.017
polyol metabolic process GO:0019751 26 0.017
receptor biosynthetic process GO:0032800 3 0.017
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
nadph regeneration GO:0006740 2 0.017
cell cell junction organization GO:0045216 72 0.017
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.017
cytoplasmic transport GO:0016482 234 0.017
regulation of peptide secretion GO:0002791 77 0.017
regulation of protein kinase activity GO:0045859 232 0.017
apoptotic signaling pathway GO:0097190 306 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
regulation of homeostatic process GO:0032844 182 0.017
regulation of cell cycle GO:0051726 281 0.017
neurotransmitter catabolic process GO:0042135 3 0.016
Mouse
nucleoside metabolic process GO:0009116 246 0.016
monocyte chemotactic protein 1 production GO:0071605 1 0.016
regulation of peptide transport GO:0090087 91 0.016
female meiotic division GO:0007143 21 0.016
Fly
synaptic transmission GO:0007268 329 0.016
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.016
response to steroid hormone GO:0048545 56 0.016
regulation of glucose metabolic process GO:0010906 60 0.016
peptidyl amino acid modification GO:0018193 336 0.016
protein catabolic process GO:0030163 221 0.016
coenzyme metabolic process GO:0006732 52 0.016
positive regulation of protein modification process GO:0031401 299 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
vascular process in circulatory system GO:0003018 62 0.016
long chain fatty acid metabolic process GO:0001676 26 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
regulation of plasminogen activation GO:0010755 4 0.016
endothelial cell development GO:0001885 20 0.016
Fly
sphingolipid metabolic process GO:0006665 45 0.016
Mouse
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.015
heart morphogenesis GO:0003007 178 0.015
Fly
retina development in camera type eye GO:0060041 119 0.015
Mouse
gland development GO:0048732 330 0.015
response to peptide GO:1901652 136 0.015
peripheral nervous system development GO:0007422 53 0.015
Fly
cation homeostasis GO:0055080 212 0.015
regulation of mapk cascade GO:0043408 248 0.015
anion transport GO:0006820 177 0.015
transmission of nerve impulse GO:0019226 76 0.015
response to xenobiotic stimulus GO:0009410 13 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
cellular response to glucose stimulus GO:0071333 45 0.015
vitamin metabolic process GO:0006766 23 0.015
negative regulation of protein modification process GO:0031400 163 0.015
extracellular structure organization GO:0043062 148 0.015
mitochondrion organization GO:0007005 134 0.015
acetate metabolic process GO:0006083 1 0.015
meiotic cell cycle GO:0051321 122 0.015
Fly
carbohydrate biosynthetic process GO:0016051 74 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
peptide hormone secretion GO:0030072 109 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
methylation GO:0032259 134 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
testosterone biosynthetic process GO:0061370 2 0.015
steroid biosynthetic process GO:0006694 47 0.015
regulation of system process GO:0044057 200 0.015
renal sodium excretion GO:0035812 3 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.014
protein processing GO:0016485 163 0.014
cellular response to nutrient levels GO:0031669 64 0.014
response to stilbenoid GO:0035634 22 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
response to peptide hormone GO:0043434 127 0.014
urogenital system development GO:0001655 261 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
regulation of neuron differentiation GO:0045664 281 0.014
cellular response to steroid hormone stimulus GO:0071383 33 0.014
cellular response to carbohydrate stimulus GO:0071322 50 0.014
positive regulation of transferase activity GO:0051347 167 0.014
cell recognition GO:0008037 83 0.014
Fly
exogenous drug catabolic process GO:0042738 1 0.014
cellular response to external stimulus GO:0071496 88 0.014
regulation of cell cycle process GO:0010564 160 0.014
androgen biosynthetic process GO:0006702 4 0.014
purine containing compound catabolic process GO:0072523 213 0.014
inter male aggressive behavior GO:0002121 3 0.014
regulation of hydrolase activity GO:0051336 246 0.014
regulation of membrane potential GO:0042391 192 0.014
rhythmic process GO:0048511 174 0.014
olfactory learning GO:0008355 2 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
response to metal ion GO:0010038 47 0.014
alpha amino acid metabolic process GO:1901605 59 0.013
divalent inorganic cation transport GO:0072511 178 0.013
skin development GO:0043588 220 0.013
Fly
spermatid differentiation GO:0048515 115 0.013
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
innate immune response GO:0045087 157 0.013
lipid transport GO:0006869 98 0.013
pigment metabolic process GO:0042440 32 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
calcium ion transport GO:0006816 159 0.013
apical junction assembly GO:0043297 15 0.013
Fly
purine ribonucleotide metabolic process GO:0009150 290 0.013
fat cell differentiation GO:0045444 160 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
calcium ion homeostasis GO:0055074 127 0.013
cellular glucose homeostasis GO:0001678 52 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
circulatory system process GO:0003013 197 0.013
protein activation cascade GO:0072376 19 0.013
arachidonic acid metabolic process GO:0019369 14 0.013
developmental maturation GO:0021700 193 0.013
lipid localization GO:0010876 126 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
cellular response to hexose stimulus GO:0071331 47 0.012
sensory organ morphogenesis GO:0090596 242 0.012
positive regulation of kinase activity GO:0033674 155 0.012
extracellular matrix organization GO:0030198 147 0.012
response to vitamin a GO:0033189 1 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
regulation of proteolysis GO:0030162 164 0.012
nucleoside catabolic process GO:0009164 206 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
gonad development GO:0008406 141 0.012
positive regulation of secretion GO:0051047 130 0.012
sensory perception GO:0007600 245 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
superoxide metabolic process GO:0006801 27 0.012
negative regulation of phospholipase activity GO:0010519 4 0.012
multicellular organism growth GO:0035264 161 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of response to wounding GO:1903034 189 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
regulation of cell projection organization GO:0031344 206 0.012
renal tubular secretion GO:0097254 2 0.012
sensory perception of chemical stimulus GO:0007606 51 0.012
nucleotide catabolic process GO:0009166 217 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
positive regulation of fatty acid oxidation GO:0046321 4 0.012
endocytosis GO:0006897 168 0.012
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
meiotic chromosome segregation GO:0045132 19 0.012
Fly
regulation of carbohydrate metabolic process GO:0006109 75 0.012
aldehyde catabolic process GO:0046185 4 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of organelle organization GO:0033043 289 0.012
cofactor transport GO:0051181 4 0.012
nucleocytoplasmic transport GO:0006913 139 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.011
fatty acid biosynthetic process GO:0006633 41 0.011
cellular response to monosaccharide stimulus GO:0071326 47 0.011
regulation of metal ion transport GO:0010959 106 0.011
response to oxygen levels GO:0070482 62 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.011
inflammatory response GO:0006954 244 0.011
ossification GO:0001503 216 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
tetrapyrrole metabolic process GO:0033013 22 0.011
estrogen secretion GO:0035937 1 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
cellular respiration GO:0045333 38 0.011
response to monosaccharide GO:0034284 67 0.011
regulation of defense response to bacterium GO:1900424 3 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
liver development GO:0001889 66 0.011
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 1 0.011
endothelium development GO:0003158 45 0.011
Fly
cardiac muscle contraction GO:0060048 32 0.011
saturated monocarboxylic acid metabolic process GO:0032788 2 0.011
t cell activation GO:0042110 289 0.011
stress activated mapk cascade GO:0051403 80 0.011
protein oligomerization GO:0051259 67 0.011
Mouse
positive regulation of secretion by cell GO:1903532 114 0.011
stem cell differentiation GO:0048863 268 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
endothelial cell differentiation GO:0045446 41 0.011
Fly
heme metabolic process GO:0042168 16 0.011
myeloid cell differentiation GO:0030099 233 0.011
ceramide metabolic process GO:0006672 31 0.011
Mouse
response to drug GO:0042493 75 0.011
very low density lipoprotein particle assembly GO:0034379 2 0.011
Mouse
anatomical structure homeostasis GO:0060249 145 0.011
striated muscle tissue development GO:0014706 293 0.011
response to insulin GO:0032868 100 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
organic acid transport GO:0015849 101 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of body fluid levels GO:0050878 162 0.011
kidney development GO:0001822 213 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
response to nitrosative stress GO:0051409 1 0.011
cytokine metabolic process GO:0042107 71 0.011
glycerolipid biosynthetic process GO:0045017 50 0.011
divalent metal ion transport GO:0070838 172 0.010
positive regulation of cell death GO:0010942 224 0.010
regulation of fatty acid oxidation GO:0046320 10 0.010
protein localization to organelle GO:0033365 185 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
lipid homeostasis GO:0055088 63 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
ras protein signal transduction GO:0007265 77 0.010
cell cell junction assembly GO:0007043 27 0.010
Fly
regulation of renal sodium excretion GO:0035813 3 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
positive regulation of growth GO:0045927 104 0.010
protein targeting GO:0006605 143 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
response to starvation GO:0042594 65 0.010
monosaccharide biosynthetic process GO:0046364 44 0.010
phospholipid metabolic process GO:0006644 87 0.010
single organism cell adhesion GO:0098602 156 0.010
intracellular protein transport GO:0006886 204 0.010
response to growth factor GO:0070848 198 0.010
nuclear import GO:0051170 95 0.010
mitotic cell cycle GO:0000278 195 0.010
development of primary sexual characteristics GO:0045137 143 0.010
neuronal action potential GO:0019228 54 0.010

Ces1e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
nervous system disease DOID:863 0 0.021
disease of anatomical entity DOID:7 0 0.021
neurodegenerative disease DOID:1289 0 0.017
central nervous system disease DOID:331 0 0.017
disease of cellular proliferation DOID:14566 0 0.012