Mus musculus

0 known processes

Cfhr1

complement factor H-related 1

(Aliases: CFHRB,MGC130590,Cfhl1,AI194696)

Cfhr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
medium chain fatty acid metabolic process GO:0051791 1 0.630
glucuronate metabolic process GO:0019585 2 0.576
response to phenylpropanoid GO:0080184 22 0.545
cellular response to testosterone stimulus GO:0071394 1 0.480
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.450
naphthalene metabolic process GO:0018931 1 0.418
cellular lipid metabolic process GO:0044255 323 0.416
uronic acid metabolic process GO:0006063 2 0.405
monocarboxylic acid metabolic process GO:0032787 191 0.361
calcitriol biosynthetic process from calciol GO:0036378 3 0.357
steroid metabolic process GO:0008202 119 0.350
lipid biosynthetic process GO:0008610 179 0.276
secondary alcohol metabolic process GO:1902652 3 0.270
vitamin d biosynthetic process GO:0042368 3 0.264
oxidative demethylation GO:0070989 1 0.256
cellular alcohol metabolic process GO:0044107 3 0.254
cellular alcohol biosynthetic process GO:0044108 3 0.244
vitamin d3 metabolic process GO:0070640 3 0.230
cellular ketone metabolic process GO:0042180 84 0.210
organic hydroxy compound metabolic process GO:1901615 203 0.204
small molecule biosynthetic process GO:0044283 132 0.199
fat soluble vitamin biosynthetic process GO:0042362 4 0.183
response to stilbenoid GO:0035634 22 0.175
response to organic cyclic compound GO:0014070 198 0.174
protein maturation GO:0051604 176 0.174
oxidation reduction process GO:0055114 342 0.172
positive regulation of steroid hormone secretion GO:2000833 2 0.169
naphthalene containing compound metabolic process GO:0090420 1 0.160
toxin catabolic process GO:0009407 1 0.157
immune effector process GO:0002252 321 0.156
regulation of cellular ketone metabolic process GO:0010565 66 0.147
cofactor metabolic process GO:0051186 80 0.145
cellular response to food GO:0071240 1 0.143
fatty acid metabolic process GO:0006631 121 0.138
sulfate assimilation GO:0000103 3 0.131
xenobiotic catabolic process GO:0042178 1 0.130
response to lipopolysaccharide GO:0032496 128 0.128
cellular response to cadmium ion GO:0071276 3 0.120
secondary metabolite catabolic process GO:0090487 1 0.118
regulation of hormone levels GO:0010817 211 0.115
response to testosterone GO:0033574 3 0.113
cellular response to lipid GO:0071396 145 0.104
response to steroid hormone GO:0048545 56 0.101
blood circulation GO:0008015 195 0.101
porphyrin containing compound metabolic process GO:0006778 22 0.100
regulation of inflammatory response GO:0050727 147 0.097
cellular amino acid metabolic process GO:0006520 103 0.097
positive regulation of estrogen secretion GO:2000863 1 0.097
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.097
alcohol metabolic process GO:0006066 116 0.094
response to molecule of bacterial origin GO:0002237 143 0.090
response to inorganic substance GO:0010035 96 0.088
heme metabolic process GO:0042168 16 0.088
lipid catabolic process GO:0016042 69 0.081
protein processing GO:0016485 163 0.077
amine metabolic process GO:0009308 45 0.077
circulatory system process GO:0003013 197 0.076
regulation of complement activation GO:0030449 7 0.074
neutral lipid metabolic process GO:0006638 57 0.073
regulation of protein activation cascade GO:2000257 7 0.069
cellular response to hormone stimulus GO:0032870 150 0.069
organic hydroxy compound biosynthetic process GO:1901617 77 0.065
regulation of estrogen secretion GO:2000861 1 0.064
fatty acid derivative metabolic process GO:1901568 33 0.064
tetrapyrrole metabolic process GO:0033013 22 0.064
vitamin metabolic process GO:0006766 23 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.063
positive regulation of cellular amine metabolic process GO:0033240 5 0.062
renal tubular secretion GO:0097254 2 0.062
unsaturated fatty acid metabolic process GO:0033559 31 0.061
monosaccharide metabolic process GO:0005996 106 0.061
inflammatory response GO:0006954 244 0.059
thermosensory behavior GO:0040040 1 0.057
cellular amine metabolic process GO:0044106 44 0.057
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.057
regulation of defense response GO:0031347 233 0.056
lipid localization GO:0010876 126 0.056
response to peptide GO:1901652 136 0.055
response to organonitrogen compound GO:0010243 246 0.055
inter male aggressive behavior GO:0002121 3 0.055
protein activation cascade GO:0072376 19 0.055
vascular process in circulatory system GO:0003018 62 0.054
icosanoid metabolic process GO:0006690 33 0.052
terpenoid metabolic process GO:0006721 25 0.051
carbohydrate metabolic process GO:0005975 230 0.051
response to peptide hormone GO:0043434 127 0.050
long chain fatty acid metabolic process GO:0001676 26 0.050
pigment metabolic process GO:0042440 32 0.050
organic acid biosynthetic process GO:0016053 86 0.050
regulation of system process GO:0044057 200 0.049
fat soluble vitamin metabolic process GO:0006775 11 0.049
endocrine process GO:0050886 39 0.049
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.047
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.046
regulation of systemic arterial blood pressure GO:0003073 61 0.046
regulation of blood pressure GO:0008217 93 0.045
innate immune response GO:0045087 157 0.045
linoleic acid metabolic process GO:0043651 6 0.044
positive regulation of lipid transport GO:0032370 22 0.043
hematopoietic progenitor cell differentiation GO:0002244 143 0.042
transmembrane transport GO:0055085 412 0.042
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.042
cellular response to peptide GO:1901653 92 0.041
glycerolipid metabolic process GO:0046486 122 0.041
lipid transport GO:0006869 98 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
arachidonic acid metabolic process GO:0019369 14 0.039
regulation of secretion GO:0051046 274 0.038
regulation of response to wounding GO:1903034 189 0.038
regulation of lipid metabolic process GO:0019216 118 0.038
negative regulation of gluconeogenesis GO:0045721 9 0.037
estrogen secretion GO:0035937 1 0.037
complement activation GO:0006956 16 0.037
regulation of protein maturation GO:1903317 96 0.036
regulation of protein processing GO:0070613 96 0.036
regulation of secretion by cell GO:1903530 249 0.036
alcohol biosynthetic process GO:0046165 43 0.036
lipid homeostasis GO:0055088 63 0.036
polyol metabolic process GO:0019751 26 0.036
cellular response to oxidative stress GO:0034599 76 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
regulation of hormone secretion GO:0046883 88 0.034
regulation of protein kinase activity GO:0045859 232 0.034
steroid biosynthetic process GO:0006694 47 0.033
regulation of blood vessel size GO:0050880 56 0.032
sensory perception GO:0007600 245 0.032
activation of immune response GO:0002253 138 0.032
blood vessel morphogenesis GO:0048514 285 0.031
carboxylic acid biosynthetic process GO:0046394 86 0.031
response to metal ion GO:0010038 47 0.031
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.031
regulation of anatomical structure size GO:0090066 178 0.031
response to oxidative stress GO:0006979 123 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
response to xenobiotic stimulus GO:0009410 13 0.030
glucose metabolic process GO:0006006 92 0.030
hormone secretion GO:0046879 128 0.030
response to nutrient levels GO:0031667 109 0.029
regulation of hydrolase activity GO:0051336 246 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
triglyceride metabolic process GO:0006641 51 0.027
cell adhesion GO:0007155 329 0.027
isoprenoid metabolic process GO:0006720 29 0.027
cellular response to peptide hormone stimulus GO:0071375 92 0.026
positive regulation of hormone secretion GO:0046887 38 0.026
negative regulation of molecular function GO:0044092 258 0.026
multicellular organism growth GO:0035264 161 0.026
exogenous drug catabolic process GO:0042738 1 0.026
regulation of cell projection organization GO:0031344 206 0.026
glucose homeostasis GO:0042593 128 0.026
saturated monocarboxylic acid metabolic process GO:0032788 2 0.025
peptidyl amino acid modification GO:0018193 336 0.025
vasoconstriction GO:0042310 27 0.025
monocarboxylic acid biosynthetic process GO:0072330 61 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
muscle tissue development GO:0060537 308 0.025
cellular response to steroid hormone stimulus GO:0071383 33 0.024
drug metabolic process GO:0017144 4 0.024
negative regulation of lipid metabolic process GO:0045833 30 0.024
anion transport GO:0006820 177 0.024
cellular response to organic cyclic compound GO:0071407 87 0.023
negative regulation of endothelial cell migration GO:0010596 4 0.023
response to cadmium ion GO:0046686 8 0.023
cellular lipid catabolic process GO:0044242 52 0.023
positive regulation of nervous system development GO:0051962 221 0.023
ion transmembrane transport GO:0034220 361 0.023
polyol biosynthetic process GO:0046173 13 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
maintenance of location GO:0051235 89 0.023
drug catabolic process GO:0042737 2 0.023
regulation of microvillus organization GO:0032530 3 0.022
positive regulation of secretion GO:0051047 130 0.022
cation transmembrane transport GO:0098655 266 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
small molecule catabolic process GO:0044282 71 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
cellular response to ethanol GO:0071361 3 0.021
olfactory learning GO:0008355 2 0.021
cellular response to biotic stimulus GO:0071216 92 0.021
carbohydrate biosynthetic process GO:0016051 74 0.021
primary alcohol catabolic process GO:0034310 2 0.021
insulin receptor signaling pathway GO:0008286 49 0.020
circadian rhythm GO:0007623 114 0.020
cellular response to carbohydrate stimulus GO:0071322 50 0.020
acylglycerol metabolic process GO:0006639 55 0.019
sterol homeostasis GO:0055092 45 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
regulation of cell motility GO:2000145 236 0.019
striated muscle tissue development GO:0014706 293 0.019
cellular chemical homeostasis GO:0055082 215 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
regulation of kinase activity GO:0043549 249 0.019
vitamin biosynthetic process GO:0009110 7 0.019
regulation of cell cycle GO:0051726 281 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.018
sensory perception of smell GO:0007608 26 0.018
negative regulation of proteolysis GO:0045861 74 0.018
hexose metabolic process GO:0019318 98 0.018
sensory perception of chemical stimulus GO:0007606 51 0.018
positive regulation of protein modification process GO:0031401 299 0.018
gluconeogenesis GO:0006094 39 0.018
organic anion transport GO:0015711 137 0.018
apoptotic signaling pathway GO:0097190 306 0.018
response to oxygen levels GO:0070482 62 0.017
cellular response to ketone GO:1901655 12 0.017
cellular response to starvation GO:0009267 57 0.017
regulation of homeostatic process GO:0032844 182 0.017
regulation of peptidase activity GO:0052547 96 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
cholesterol homeostasis GO:0042632 44 0.017
cellular response to nutrient levels GO:0031669 64 0.017
macromolecule catabolic process GO:0009057 281 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
skin development GO:0043588 220 0.017
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.017
response to corticosteroid GO:0031960 20 0.017
negative regulation of immune system process GO:0002683 209 0.016
response to drug GO:0042493 75 0.016
positive regulation of cell death GO:0010942 224 0.016
negative regulation of endopeptidase activity GO:0010951 44 0.016
sterol metabolic process GO:0016125 58 0.016
acute inflammatory response GO:0002526 41 0.016
single organism cell adhesion GO:0098602 156 0.016
sulfur compound metabolic process GO:0006790 100 0.015
humoral immune response GO:0006959 57 0.015
regulation of cell migration GO:0030334 219 0.015
mapk cascade GO:0000165 281 0.015
epithelium migration GO:0090132 63 0.015
cellular response to inorganic substance GO:0071241 37 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
learning or memory GO:0007611 148 0.015
regulation of transferase activity GO:0051338 263 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
rna processing GO:0006396 105 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
chemotaxis GO:0006935 247 0.015
leukocyte differentiation GO:0002521 342 0.015
response to acid chemical GO:0001101 111 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
myeloid cell differentiation GO:0030099 233 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.014
regulation of multi organism process GO:0043900 111 0.014
androgen biosynthetic process GO:0006702 4 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
renal system process GO:0003014 48 0.014
carbohydrate homeostasis GO:0033500 128 0.014
positive regulation of systemic arterial blood pressure GO:0003084 9 0.014
regulation of proteolysis GO:0030162 164 0.014
regulation of angiotensin levels in blood GO:0002002 4 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
cellular response to metal ion GO:0071248 31 0.014
monosaccharide biosynthetic process GO:0046364 44 0.014
positive regulation of proteolysis GO:0045862 85 0.014
cholesterol metabolic process GO:0008203 56 0.014
gliogenesis GO:0042063 141 0.014
negative regulation of carbohydrate metabolic process GO:0045912 19 0.014
secondary metabolic process GO:0019748 18 0.013
cartilage development GO:0051216 140 0.013
regulation of steroid metabolic process GO:0019218 39 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
mitochondrion organization GO:0007005 134 0.013
aromatic compound catabolic process GO:0019439 286 0.013
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.013
positive regulation of fatty acid oxidation GO:0046321 4 0.013
regulation of organelle organization GO:0033043 289 0.013
regulation of mapk cascade GO:0043408 248 0.013
protein catabolic process GO:0030163 221 0.013
leukocyte mediated immunity GO:0002443 174 0.013
cellular homeostasis GO:0019725 240 0.013
organophosphate catabolic process GO:0046434 232 0.013
regulation of cellular component size GO:0032535 121 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
defense response to bacterium GO:0042742 119 0.013
nitrogen compound transport GO:0071705 271 0.013
hexose biosynthetic process GO:0019319 39 0.013
cellular response to hexose stimulus GO:0071331 47 0.013
response to insulin GO:0032868 100 0.013
bile acid metabolic process GO:0008206 17 0.012
gland development GO:0048732 330 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
regulation of gluconeogenesis GO:0006111 30 0.012
response to reactive oxygen species GO:0000302 56 0.012
regulation of cholesterol metabolic process GO:0090181 14 0.012
cell type specific apoptotic process GO:0097285 268 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
regulation of lipid transport GO:0032368 36 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
negative regulation of nervous system development GO:0051961 156 0.012
progesterone metabolic process GO:0042448 4 0.012
mrna metabolic process GO:0016071 84 0.012
cardiac muscle tissue development GO:0048738 130 0.012
homeostasis of number of cells GO:0048872 210 0.012
response to alcohol GO:0097305 48 0.012
succinyl coa metabolic process GO:0006104 1 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
axonogenesis GO:0007409 274 0.012
regulation of angiotensin metabolic process GO:0060177 4 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
regulation of acute inflammatory response GO:0002673 27 0.012
testosterone biosynthetic process GO:0061370 2 0.012
response to extracellular stimulus GO:0009991 127 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
female gamete generation GO:0007292 74 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
positive regulation of kinase activity GO:0033674 155 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
positive regulation of transferase activity GO:0051347 167 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
response to glucocorticoid GO:0051384 20 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular protein complex assembly GO:0043623 116 0.011
ras protein signal transduction GO:0007265 77 0.011
epidermis development GO:0008544 187 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of peptide transport GO:0090087 91 0.011
positive regulation of eosinophil migration GO:2000418 2 0.011
skeletal muscle organ development GO:0060538 163 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
organic acid transport GO:0015849 101 0.011
angiogenesis GO:0001525 201 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
cognition GO:0050890 149 0.011
cytokine production GO:0001816 319 0.011
cellular response to monosaccharide stimulus GO:0071326 47 0.011
extracellular matrix organization GO:0030198 147 0.011
organic acid catabolic process GO:0016054 51 0.011
fat cell differentiation GO:0045444 160 0.011
cation transport GO:0006812 399 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
response to corticosterone GO:0051412 1 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
skeletal system development GO:0001501 356 0.011
camera type eye development GO:0043010 266 0.010
negative regulation of protein processing GO:0010955 79 0.010
spermatogenesis GO:0007283 284 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
lymphocyte differentiation GO:0030098 242 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
defense response to other organism GO:0098542 197 0.010
developmental maturation GO:0021700 193 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
response to interferon gamma GO:0034341 34 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
placenta development GO:0001890 140 0.010
amide transport GO:0042886 138 0.010
response to starvation GO:0042594 65 0.010
establishment of blood nerve barrier GO:0008065 3 0.010
cellular response to alcohol GO:0097306 23 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
single fertilization GO:0007338 82 0.010

Cfhr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
normocytic anemia DOID:720 0 0.254
hemolytic anemia DOID:583 0 0.254
hemolytic uremic syndrome DOID:12554 0 0.254
hematopoietic system disease DOID:74 0 0.254
anemia DOID:2355 0 0.254
immune system disease DOID:2914 0 0.254
disease of anatomical entity DOID:7 0 0.254
retinal degeneration DOID:8466 0 0.061
sensory system disease DOID:0050155 0 0.061
eye and adnexa disease DOID:1492 0 0.061
retinal disease DOID:5679 0 0.061
nervous system disease DOID:863 0 0.061
eye disease DOID:5614 0 0.061
cardiovascular system disease DOID:1287 0 0.060
macular degeneration DOID:4448 0 0.034
vascular disease DOID:178 0 0.032
inherited metabolic disorder DOID:655 0 0.031
disease of metabolism DOID:0014667 0 0.031
artery disease DOID:0050828 0 0.022
essential hypertension DOID:10825 0 0.018
hypertension DOID:10763 0 0.018
degeneration of macula and posterior pole DOID:2007 0 0.017
age related macular degeneration DOID:10871 0 0.017