Mus musculus

0 known processes

Chaf1b

chromatin assembly factor 1, subunit B (p60)

(Aliases: CAF1A,CAF-Ip60,MPHOSPH7,CAF1,C76145,2600017H24Rik,CAF1P60,CAF-I p60)

Chaf1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna endoreduplication GO:0042023 4 0.368
dna metabolic process GO:0006259 303 0.277
Human Yeast
mitotic cell cycle GO:0000278 195 0.231
Zebrafish
macromolecule catabolic process GO:0009057 281 0.198
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.167
cellular amino acid metabolic process GO:0006520 103 0.155
microtubule based process GO:0007017 236 0.154
nuclear division GO:0000280 158 0.154
establishment of organelle localization GO:0051656 122 0.151
mitotic cell cycle process GO:1903047 159 0.142
regulation of cell cycle process GO:0010564 160 0.141
meiotic nuclear division GO:0007126 115 0.134
cellular response to dna damage stimulus GO:0006974 207 0.134
regulation of cell cycle GO:0051726 281 0.134
metaphase plate congression GO:0051310 2 0.116
negative regulation of mitotic cell cycle GO:0045930 58 0.114
negative regulation of cell cycle GO:0045786 123 0.108
organelle localization GO:0051640 179 0.107
dna repair GO:0006281 107 0.107
regulation of organelle organization GO:0033043 289 0.104
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.097
heterocycle catabolic process GO:0046700 280 0.090
apoptotic signaling pathway GO:0097190 306 0.086
regulation of protein kinase activity GO:0045859 232 0.081
microtubule cytoskeleton organization GO:0000226 157 0.081
meiotic cell cycle process GO:1903046 77 0.078
regulation of chromosome organization GO:0033044 83 0.076
negative regulation of cell cycle phase transition GO:1901988 48 0.076
aromatic compound catabolic process GO:0019439 286 0.076
cellular ketone metabolic process GO:0042180 84 0.073
positive regulation of cell cycle process GO:0090068 61 0.070
regulation of protein localization GO:0032880 231 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
spindle assembly involved in female meiosis GO:0007056 3 0.068
gland development GO:0048732 330 0.067
protein processing GO:0016485 163 0.065
dna integrity checkpoint GO:0031570 28 0.065
regulation of transferase activity GO:0051338 263 0.063
meiotic cell cycle GO:0051321 122 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.062
chromosome segregation GO:0007059 48 0.060
gonad development GO:0008406 141 0.059
positive regulation of cell cycle GO:0045787 92 0.057
female meiosis chromosome segregation GO:0016321 1 0.056
regulation of mitotic cell cycle GO:0007346 126 0.054
peptidyl amino acid modification GO:0018193 336 0.054
regulation of proteolysis GO:0030162 164 0.054
establishment or maintenance of cell polarity GO:0007163 86 0.054
regulation of kinase activity GO:0043549 249 0.053
regulation of cellular ketone metabolic process GO:0010565 66 0.053
development of primary sexual characteristics GO:0045137 143 0.052
cellular amine metabolic process GO:0044106 44 0.052
regulation of cellular response to stress GO:0080135 159 0.052
organelle assembly GO:0070925 177 0.052
nuclear membrane organization GO:0071763 4 0.051
centrosome duplication GO:0051298 16 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
regulation of cell division GO:0051302 76 0.049
posttranscriptional regulation of gene expression GO:0010608 155 0.049
cellular component assembly involved in morphogenesis GO:0010927 139 0.048
amine metabolic process GO:0009308 45 0.047
muscle cell differentiation GO:0042692 261 0.044
cell cycle checkpoint GO:0000075 47 0.043
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.042
positive regulation of organelle organization GO:0010638 128 0.042
regulation of cell cycle phase transition GO:1901987 77 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
organelle fission GO:0048285 170 0.042
dna dependent dna replication GO:0006261 24 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
double strand break repair GO:0006302 48 0.041
anatomical structure homeostasis GO:0060249 145 0.041
cell fate commitment GO:0045165 210 0.040
endocytosis GO:0006897 168 0.040
regulation of mitosis GO:0007088 29 0.040
negative regulation of cellular component organization GO:0051129 194 0.040
nuclear dna replication GO:0033260 3 0.039
maintenance of location GO:0051235 89 0.039
endomembrane system organization GO:0010256 147 0.039
regulation of t cell activation GO:0050863 170 0.038
histone modification GO:0016570 159 0.038
mitotic nuclear division GO:0007067 48 0.038
establishment of spindle localization GO:0051293 19 0.037
dna recombination GO:0006310 92 0.037
chromatin organization GO:0006325 206 0.036
Human Yeast
stem cell differentiation GO:0048863 268 0.036
positive regulation of protein kinase activity GO:0045860 144 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
reactive oxygen species metabolic process GO:0072593 84 0.036
purine nucleotide metabolic process GO:0006163 302 0.036
positive regulation of transferase activity GO:0051347 167 0.035
regulation of anatomical structure size GO:0090066 178 0.035
leukocyte proliferation GO:0070661 172 0.034
positive regulation of protein modification process GO:0031401 299 0.034
wnt signaling pathway GO:0016055 188 0.034
myosin filament organization GO:0031033 3 0.034
negative regulation of immune system process GO:0002683 209 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
negative regulation of organelle organization GO:0010639 90 0.033
cellular protein complex assembly GO:0043623 116 0.032
negative regulation of cell proliferation GO:0008285 296 0.032
protein catabolic process GO:0030163 221 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
dna replication initiation GO:0006270 5 0.032
molting cycle GO:0042303 90 0.032
mitotic cell cycle checkpoint GO:0007093 31 0.031
muscle cell development GO:0055001 133 0.031
protein maturation GO:0051604 176 0.031
negative regulation of protein metabolic process GO:0051248 282 0.030
cellular lipid metabolic process GO:0044255 323 0.030
mapk cascade GO:0000165 281 0.030
nucleotide metabolic process GO:0009117 332 0.030
regulation of lymphocyte apoptotic process GO:0070228 41 0.029
cell cycle g1 s phase transition GO:0044843 57 0.029
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
regulation of mitotic cell cycle phase transition GO:1901990 73 0.029
positive regulation of mapk cascade GO:0043410 170 0.029
regulation of cellular component size GO:0032535 121 0.028
anion transport GO:0006820 177 0.028
negative regulation of molecular function GO:0044092 258 0.028
germ cell development GO:0007281 185 0.028
t cell proliferation GO:0042098 120 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
blood vessel morphogenesis GO:0048514 285 0.027
myosin filament assembly GO:0031034 2 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
regulation of nuclear cell cycle dna replication GO:0033262 2 0.027
striated muscle myosin thick filament assembly GO:0071688 1 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.026
stem cell maintenance GO:0019827 130 0.026
t cell activation GO:0042110 289 0.026
digestive system development GO:0055123 200 0.026
leukocyte differentiation GO:0002521 342 0.025
regulation of protein secretion GO:0050708 82 0.025
regulation of secretion GO:0051046 274 0.025
positive regulation of cell development GO:0010720 237 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.025
myeloid cell differentiation GO:0030099 233 0.025
covalent chromatin modification GO:0016569 163 0.024
response to inorganic substance GO:0010035 96 0.024
cellular response to biotic stimulus GO:0071216 92 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
immune effector process GO:0002252 321 0.024
stem cell development GO:0048864 219 0.024
regulation of binding GO:0051098 111 0.024
purine containing compound metabolic process GO:0072521 311 0.024
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.024
regulation of cell motility GO:2000145 236 0.024
cell division GO:0051301 120 0.023
oxidation reduction process GO:0055114 342 0.023
neural tube development GO:0021915 160 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
protein dna complex subunit organization GO:0071824 28 0.023
Human Yeast
ribose phosphate metabolic process GO:0019693 291 0.022
spindle localization GO:0051653 22 0.022
lymphocyte differentiation GO:0030098 242 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
negative regulation of protein modification process GO:0031400 163 0.022
cell type specific apoptotic process GO:0097285 268 0.022
regulation of endopeptidase activity GO:0052548 89 0.022
negative regulation of protein processing GO:0010955 79 0.022
fertilization GO:0009566 127 0.022
striated muscle tissue development GO:0014706 293 0.022
adaptive immune response GO:0002250 155 0.022
regulation of cytokine production GO:0001817 266 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
t cell differentiation in thymus GO:0033077 77 0.021
protein import GO:0017038 101 0.021
regulation of hydrolase activity GO:0051336 246 0.021
protein polymerization GO:0051258 57 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
actin filament polymerization GO:0030041 44 0.021
response to cell cycle checkpoint signaling GO:0072396 1 0.021
organic anion transport GO:0015711 137 0.021
protein targeting GO:0006605 143 0.021
regulation of cell activation GO:0050865 289 0.021
hepaticobiliary system development GO:0061008 67 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.020
cellular response to lipid GO:0071396 145 0.020
multicellular organism growth GO:0035264 161 0.020
negative regulation of cell development GO:0010721 169 0.020
cytokine production GO:0001816 319 0.020
regulation of protein transport GO:0051223 163 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
cytokinetic process GO:0032506 2 0.020
mitotic chromosome condensation GO:0007076 1 0.020
cell growth GO:0016049 130 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
embryonic epithelial tube formation GO:0001838 130 0.020
regulation of mitotic sister chromatid segregation GO:0033047 12 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
homeostasis of number of cells GO:0048872 210 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
respiratory tube development GO:0030323 167 0.019
negative regulation of mitosis GO:0045839 10 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
negative regulation of cell cycle process GO:0010948 69 0.018
glial cell differentiation GO:0010001 131 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
epithelial cell development GO:0002064 159 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
synapsis GO:0007129 34 0.018
positive regulation of nervous system development GO:0051962 221 0.018
blastocyst development GO:0001824 80 0.018
centrosome cycle GO:0007098 23 0.018
g1 s transition of mitotic cell cycle GO:0000082 57 0.018
male gamete generation GO:0048232 285 0.018
cell junction organization GO:0034330 77 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
meiosis i GO:0007127 60 0.017
dephosphorylation GO:0016311 129 0.017
t cell differentiation GO:0030217 174 0.017
positive regulation of kinase activity GO:0033674 155 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
positive regulation of t cell activation GO:0050870 101 0.017
cilium morphogenesis GO:0060271 102 0.017
spermatogenesis GO:0007283 284 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
gene silencing GO:0016458 38 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
muscle tissue development GO:0060537 308 0.017
recombinational repair GO:0000725 21 0.017
protein localization to organelle GO:0033365 185 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
spindle assembly involved in mitosis GO:0090307 4 0.016
protein depolymerization GO:0051261 34 0.016
membrane organization GO:0061024 245 0.016
camera type eye development GO:0043010 266 0.016
Zebrafish
nucleocytoplasmic transport GO:0006913 139 0.016
nuclear envelope organization GO:0006998 11 0.016
ras protein signal transduction GO:0007265 77 0.016
positive regulation of cell activation GO:0050867 158 0.016
regulation of t cell proliferation GO:0042129 92 0.016
regulation of protein stability GO:0031647 52 0.016
organophosphate catabolic process GO:0046434 232 0.016
positive regulation of cell cycle phase transition GO:1901989 17 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.015
mitotic cytokinesis GO:0000281 4 0.015
mitotic sister chromatid separation GO:0051306 9 0.015
nucleus organization GO:0006997 45 0.015
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
cytoplasmic transport GO:0016482 234 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
developmental maturation GO:0021700 193 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
positive regulation of g0 to g1 transition GO:0070318 2 0.015
positive regulation of mitotic cell cycle GO:0045931 41 0.015
liver development GO:0001889 66 0.015
digestive tract morphogenesis GO:0048546 147 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
cellular response to inorganic substance GO:0071241 37 0.015
response to extracellular stimulus GO:0009991 127 0.015
ossification GO:0001503 216 0.015
cell aging GO:0007569 35 0.015
regulation of defense response GO:0031347 233 0.015
striated muscle cell development GO:0055002 125 0.015
b cell activation GO:0042113 161 0.015
response to lipopolysaccharide GO:0032496 128 0.015
primary neural tube formation GO:0014020 95 0.015
regulation of neuron differentiation GO:0045664 281 0.014
dna packaging GO:0006323 30 0.014
Human Yeast
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.014
leukocyte mediated immunity GO:0002443 174 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.014
single organism nuclear import GO:1902593 95 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
cell maturation GO:0048469 127 0.014
actin cytoskeleton organization GO:0030036 220 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
negative regulation of sister chromatid segregation GO:0033046 7 0.014
nuclear transport GO:0051169 139 0.014
localization within membrane GO:0051668 4 0.014
regulation of protein catabolic process GO:0042176 108 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
positive regulation of cell death GO:0010942 224 0.014
cellularization GO:0007349 1 0.014
intracellular protein transport GO:0006886 204 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.013
digestive tract development GO:0048565 190 0.013
purine nucleobase biosynthetic process GO:0009113 3 0.013
chromatin modification GO:0016568 187 0.013
b cell apoptotic process GO:0001783 19 0.013
sister chromatid cohesion GO:0007062 12 0.013
nucleoside catabolic process GO:0009164 206 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
epithelial cell proliferation GO:0050673 174 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
dna biosynthetic process GO:0071897 22 0.013
cell cycle switching GO:0060184 1 0.013
srebp signaling pathway GO:0032933 4 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
lipid localization GO:0010876 126 0.013
mitotic sister chromatid segregation GO:0000070 14 0.013
centrosome organization GO:0051297 26 0.013
epithelial tube formation GO:0072175 130 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of nuclear division GO:0051783 56 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
response to acid chemical GO:0001101 111 0.013
b cell activation involved in immune response GO:0002312 50 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
glycerolipid metabolic process GO:0046486 122 0.012
positive regulation of lymphocyte proliferation GO:0050671 70 0.012
rho protein signal transduction GO:0007266 32 0.012
lipid biosynthetic process GO:0008610 179 0.012
rhythmic process GO:0048511 174 0.012
peptidyl serine modification GO:0018209 83 0.012
regulation of leukocyte apoptotic process GO:2000106 56 0.012
stress activated mapk cascade GO:0051403 80 0.012
regulation of exit from mitosis GO:0007096 1 0.012
spindle assembly involved in meiosis GO:0090306 4 0.012
cardiocyte differentiation GO:0035051 87 0.012
stem cell proliferation GO:0072089 117 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
meiotic chromosome segregation GO:0045132 19 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
erythrocyte differentiation GO:0030218 88 0.012
positive regulation of t cell proliferation GO:0042102 52 0.012
negative regulation of protein transport GO:0051224 46 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
respiratory system development GO:0060541 190 0.012
signal transduction by p53 class mediator GO:0072331 51 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
reciprocal dna recombination GO:0035825 16 0.012
neural tube formation GO:0001841 108 0.011
lymphocyte apoptotic process GO:0070227 54 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of mapk cascade GO:0043408 248 0.011
activation of immune response GO:0002253 138 0.011
lung development GO:0030324 164 0.011
response to steroid hormone GO:0048545 56 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
female meiotic division GO:0007143 21 0.011
lymphocyte proliferation GO:0046651 164 0.011
small molecule biosynthetic process GO:0044283 132 0.011
rna processing GO:0006396 105 0.011
leukocyte migration GO:0050900 124 0.011
cellular homeostasis GO:0019725 240 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.011
female gamete generation GO:0007292 74 0.011
oocyte construction GO:0007308 2 0.011
dna replication GO:0006260 52 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
regulation of chromatin organization GO:1902275 57 0.011
single fertilization GO:0007338 82 0.011
response to organonitrogen compound GO:0010243 246 0.011
regulation of response to wounding GO:1903034 189 0.011
cellular response to sterol depletion GO:0071501 4 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
sister chromatid segregation GO:0000819 20 0.011
tube formation GO:0035148 140 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.011
lateral inhibition GO:0046331 1 0.011
cellular response to external stimulus GO:0071496 88 0.011
regulation of inflammatory response GO:0050727 147 0.010
negative regulation of proteolysis GO:0045861 74 0.010
cation transport GO:0006812 399 0.010
positive regulation of cytokine production GO:0001819 174 0.010
t cell apoptotic process GO:0070231 39 0.010
carboxylic acid transport GO:0046942 100 0.010
regulation of dna dependent dna replication GO:0090329 8 0.010
leukocyte apoptotic process GO:0071887 71 0.010
nucleus localization GO:0051647 20 0.010
cytokine biosynthetic process GO:0042089 68 0.010
developmental cell growth GO:0048588 84 0.010
positive regulation of growth GO:0045927 104 0.010
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.010
wound healing GO:0042060 157 0.010
regulation of system process GO:0044057 200 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
multicellular organismal aging GO:0010259 24 0.010
cleavage furrow formation GO:0036089 2 0.010

Chaf1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.037
cancer DOID:162 0 0.037
organ system cancer DOID:0050686 0 0.037
inherited metabolic disorder DOID:655 0 0.031
disease of metabolism DOID:0014667 0 0.031
gastrointestinal system cancer DOID:3119 0 0.017
intestinal cancer DOID:10155 0 0.012
large intestine cancer DOID:5672 0 0.012