Mus musculus

79 known processes

Chfr

checkpoint with forkhead and ring finger domains

(Aliases: C230082M18,5730484M20Rik,RNF116)

Chfr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule catabolic process GO:0009057 281 0.090
chromatin modification GO:0016568 187 0.081
muscle tissue development GO:0060537 308 0.074
cellular amino acid metabolic process GO:0006520 103 0.067
cellular amine metabolic process GO:0044106 44 0.065
organic cyclic compound catabolic process GO:1901361 295 0.064
regulation of cellular amine metabolic process GO:0033238 20 0.059
protein modification by small protein conjugation GO:0032446 187 0.054
cellular nitrogen compound catabolic process GO:0044270 280 0.052
chromatin organization GO:0006325 206 0.050
cell type specific apoptotic process GO:0097285 268 0.048
camera type eye development GO:0043010 266 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
cellular ketone metabolic process GO:0042180 84 0.045
heterocycle catabolic process GO:0046700 280 0.045
peptidyl amino acid modification GO:0018193 336 0.044
histone modification GO:0016570 159 0.044
organelle assembly GO:0070925 177 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
spermatogenesis GO:0007283 284 0.043
cellular macromolecule catabolic process GO:0044265 206 0.043
aromatic compound catabolic process GO:0019439 286 0.042
skeletal muscle organ development GO:0060538 163 0.042
amine metabolic process GO:0009308 45 0.041
rna catabolic process GO:0006401 29 0.041
protein localization to organelle GO:0033365 185 0.040
cation transport GO:0006812 399 0.040
transmembrane transport GO:0055085 412 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
actin cytoskeleton organization GO:0030036 220 0.039
regulation of organelle organization GO:0033043 289 0.037
muscle cell differentiation GO:0042692 261 0.036
male gamete generation GO:0048232 285 0.036
apoptotic signaling pathway GO:0097190 306 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
striated muscle tissue development GO:0014706 293 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
nuclear transport GO:0051169 139 0.032
mrna catabolic process GO:0006402 22 0.031
regulation of hydrolase activity GO:0051336 246 0.030
positive regulation of protein modification process GO:0031401 299 0.029
regulation of cell migration GO:0030334 219 0.029
ion transmembrane transport GO:0034220 361 0.029
positive regulation of programmed cell death GO:0043068 218 0.028
cation transmembrane transport GO:0098655 266 0.027
cytoplasmic transport GO:0016482 234 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.026
carbohydrate metabolic process GO:0005975 230 0.026
mrna metabolic process GO:0016071 84 0.026
cellular homeostasis GO:0019725 240 0.025
regulation of cellular response to stress GO:0080135 159 0.025
intracellular protein transport GO:0006886 204 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
covalent chromatin modification GO:0016569 163 0.025
regulation of proteolysis GO:0030162 164 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
maintenance of location GO:0051235 89 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
protein targeting GO:0006605 143 0.024
positive regulation of cell development GO:0010720 237 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
cell adhesion GO:0007155 329 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
negative regulation of molecular function GO:0044092 258 0.024
protein alkylation GO:0008213 81 0.024
sensory organ morphogenesis GO:0090596 242 0.024
nitrogen compound transport GO:0071705 271 0.023
compound eye development GO:0048749 1 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
neuron apoptotic process GO:0051402 142 0.023
angiogenesis GO:0001525 201 0.023
regulation of cell projection organization GO:0031344 206 0.022
protein methylation GO:0006479 81 0.022
neuronal action potential GO:0019228 54 0.022
regulation of cytokine production GO:0001817 266 0.022
immune effector process GO:0002252 321 0.022
nuclear transcribed mrna catabolic process GO:0000956 16 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
ribose phosphate metabolic process GO:0019693 291 0.021
cellular lipid metabolic process GO:0044255 323 0.021
nucleoside metabolic process GO:0009116 246 0.021
regulation of cytoplasmic transport GO:1903649 112 0.021
purine containing compound metabolic process GO:0072521 311 0.021
cellular ion homeostasis GO:0006873 165 0.021
mapk cascade GO:0000165 281 0.021
blood vessel morphogenesis GO:0048514 285 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
positive regulation of protein kinase activity GO:0045860 144 0.020
cell division GO:0051301 120 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
mitotic cell cycle GO:0000278 195 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
regulation of protein localization GO:0032880 231 0.020
response to organonitrogen compound GO:0010243 246 0.020
membrane organization GO:0061024 245 0.020
nuclear import GO:0051170 95 0.020
sequestering of metal ion GO:0051238 19 0.020
positive regulation of cell death GO:0010942 224 0.020
methylation GO:0032259 134 0.020
regulation of membrane potential GO:0042391 192 0.020
response to growth factor GO:0070848 198 0.020
regulation of cell motility GO:2000145 236 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
ras protein signal transduction GO:0007265 77 0.019
protein localization to nucleus GO:0034504 121 0.019
cellular protein complex assembly GO:0043623 116 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
exocytosis GO:0006887 121 0.019
dephosphorylation GO:0016311 129 0.019
rna interference GO:0016246 2 0.019
peptidyl serine modification GO:0018209 83 0.019
protein autophosphorylation GO:0046777 61 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
response to radiation GO:0009314 165 0.019
organelle localization GO:0051640 179 0.019
regulation of neuron death GO:1901214 134 0.019
multicellular organism growth GO:0035264 161 0.018
divalent inorganic cation transport GO:0072511 178 0.018
asymmetric stem cell division GO:0098722 3 0.018
regulation of protein kinase activity GO:0045859 232 0.018
regulation of intracellular transport GO:0032386 159 0.018
regulation of anatomical structure size GO:0090066 178 0.018
cellular protein catabolic process GO:0044257 155 0.018
organelle fission GO:0048285 170 0.018
neuron death GO:0070997 154 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
cation homeostasis GO:0055080 212 0.018
protein ubiquitination GO:0016567 171 0.018
regulation of transferase activity GO:0051338 263 0.017
lipid biosynthetic process GO:0008610 179 0.017
regulation of neuron differentiation GO:0045664 281 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
endocytosis GO:0006897 168 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
protein catabolic process GO:0030163 221 0.017
regulation of chromosome organization GO:0033044 83 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regulation of histone modification GO:0031056 56 0.017
forebrain development GO:0030900 302 0.017
regulation of secretion by cell GO:1903530 249 0.017
negative regulation of cell cycle GO:0045786 123 0.017
Human
regulation of ion transport GO:0043269 215 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
microtubule based process GO:0007017 236 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
t cell activation GO:0042110 289 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.016
protein import GO:0017038 101 0.016
cellular chemical homeostasis GO:0055082 215 0.016
positive regulation of organelle organization GO:0010638 128 0.016
retina development in camera type eye GO:0060041 119 0.016
homeostasis of number of cells GO:0048872 210 0.016
regulation of chromatin organization GO:1902275 57 0.016
action potential GO:0001508 78 0.016
macromolecule methylation GO:0043414 120 0.016
negative regulation of neuron death GO:1901215 98 0.016
protein maturation GO:0051604 176 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
spermatid differentiation GO:0048515 115 0.016
germ cell development GO:0007281 185 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
skeletal system morphogenesis GO:0048705 203 0.016
gland development GO:0048732 330 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
transmission of nerve impulse GO:0019226 76 0.016
cellular response to nutrient levels GO:0031669 64 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
positive regulation of nervous system development GO:0051962 221 0.016
protein processing GO:0016485 163 0.016
glycerolipid metabolic process GO:0046486 122 0.015
cell substrate adhesion GO:0031589 130 0.015
regulation of histone methylation GO:0031060 30 0.015
divalent metal ion transport GO:0070838 172 0.015
single organism nuclear import GO:1902593 95 0.015
regulation of mapk cascade GO:0043408 248 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
glucose homeostasis GO:0042593 128 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
regulation of transmembrane transport GO:0034762 128 0.015
regulation of secretion GO:0051046 274 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
skeletal system development GO:0001501 356 0.015
rap protein signal transduction GO:0032486 3 0.015
positive regulation of transferase activity GO:0051347 167 0.015
spermatid development GO:0007286 108 0.015
negative regulation of organelle organization GO:0010639 90 0.015
respiratory system development GO:0060541 190 0.015
regulation of kinase activity GO:0043549 249 0.015
respiratory tube development GO:0030323 167 0.015
metencephalon development GO:0022037 89 0.015
purine containing compound catabolic process GO:0072523 213 0.015
peptidyl serine phosphorylation GO:0018105 74 0.014
limb development GO:0060173 166 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
cell activation involved in immune response GO:0002263 126 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
leukocyte mediated immunity GO:0002443 174 0.014
regulation of cell activation GO:0050865 289 0.014
positive regulation of kinase activity GO:0033674 155 0.014
sequestering of calcium ion GO:0051208 18 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
calcium ion homeostasis GO:0055074 127 0.014
response to light stimulus GO:0009416 135 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
regulation of hormone levels GO:0010817 211 0.014
synaptic transmission GO:0007268 329 0.014
regulation of muscle tissue development GO:1901861 97 0.014
lung development GO:0030324 164 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
chemotaxis GO:0006935 247 0.013
metal ion homeostasis GO:0055065 189 0.013
posttranscriptional gene silencing GO:0016441 10 0.013
mitotic cell cycle process GO:1903047 159 0.013
Human
locomotory behavior GO:0007626 195 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of cell cycle GO:0051726 281 0.013
Human
carbohydrate homeostasis GO:0033500 128 0.013
nucleotide catabolic process GO:0009166 217 0.013
organophosphate catabolic process GO:0046434 232 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
ear development GO:0043583 200 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
regulation of neuron projection development GO:0010975 169 0.013
appendage development GO:0048736 166 0.013
activation of immune response GO:0002253 138 0.013
multicellular organismal signaling GO:0035637 91 0.013
viral gene expression GO:0019080 3 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
myeloid cell differentiation GO:0030099 233 0.013
endomembrane system organization GO:0010256 147 0.013
regulation of cell growth GO:0001558 91 0.013
axonogenesis GO:0007409 274 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
regulation of protein transport GO:0051223 163 0.013
rho protein signal transduction GO:0007266 32 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
response to transforming growth factor beta GO:0071559 88 0.012
dna metabolic process GO:0006259 303 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
cytokinetic process GO:0032506 2 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
muscle cell development GO:0055001 133 0.012
innate immune response GO:0045087 157 0.012
histone lysine demethylation GO:0070076 13 0.012
stem cell differentiation GO:0048863 268 0.012
regulation of chromatin modification GO:1903308 57 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
myotube differentiation GO:0014902 105 0.012
regulation of cell cycle process GO:0010564 160 0.012
Human
cellular response to extracellular stimulus GO:0031668 81 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
cell growth GO:0016049 130 0.012
cytokine production GO:0001816 319 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
Human
response to acid chemical GO:0001101 111 0.012
regulation of binding GO:0051098 111 0.012
leukocyte differentiation GO:0002521 342 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
regulation of cellular component size GO:0032535 121 0.012
regulation of ossification GO:0030278 112 0.012
ameboidal type cell migration GO:0001667 128 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
rhythmic process GO:0048511 174 0.012
response to peptide hormone GO:0043434 127 0.012
negative regulation of immune system process GO:0002683 209 0.012
demethylation GO:0070988 23 0.012
sensory perception of sound GO:0007605 97 0.012
negative regulation of cell development GO:0010721 169 0.012
cellular response to starvation GO:0009267 57 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
histone methylation GO:0016571 71 0.012
ossification GO:0001503 216 0.012
regulation of metal ion transport GO:0010959 106 0.012
cellular response to external stimulus GO:0071496 88 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
sensory perception GO:0007600 245 0.011
wnt signaling pathway GO:0016055 188 0.011
gtp metabolic process GO:0046039 144 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
response to insulin GO:0032868 100 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
calcium ion transport GO:0006816 159 0.011
appendage morphogenesis GO:0035107 149 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
protein localization to membrane GO:0072657 108 0.011
response to extracellular stimulus GO:0009991 127 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
meiotic nuclear division GO:0007126 115 0.011
lymphocyte differentiation GO:0030098 242 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
positive regulation of growth GO:0045927 104 0.011
rna processing GO:0006396 105 0.011
viral transcription GO:0019083 3 0.011
anion transport GO:0006820 177 0.011
inflammatory response GO:0006954 244 0.011
attachment of spindle microtubules to kinetochore GO:0008608 4 0.011
alcohol metabolic process GO:0006066 116 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
response to oxidative stress GO:0006979 123 0.011
actin filament organization GO:0007015 113 0.011
nuclear division GO:0000280 158 0.011
nucleoside catabolic process GO:0009164 206 0.011
response to peptide GO:1901652 136 0.011
regulation of peptidase activity GO:0052547 96 0.011
response to nutrient levels GO:0031667 109 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
oxidation reduction process GO:0055114 342 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
establishment of protein localization to membrane GO:0090150 54 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
skin development GO:0043588 220 0.011
photoreceptor cell differentiation GO:0046530 52 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
protein import into nucleus GO:0006606 95 0.010
glycoprotein metabolic process GO:0009100 116 0.010
heart morphogenesis GO:0003007 178 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
myosin filament organization GO:0031033 3 0.010
macromolecular complex disassembly GO:0032984 43 0.010
positive regulation of immune effector process GO:0002699 107 0.010
regulation of system process GO:0044057 200 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
protein polymerization GO:0051258 57 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
Human
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.010
regulation of vasculature development GO:1901342 88 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
small molecule biosynthetic process GO:0044283 132 0.010
regulation of androgen receptor signaling pathway GO:0060765 3 0.010
meiotic cell cycle GO:0051321 122 0.010

Chfr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.025
organ system cancer DOID:0050686 0 0.025
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
central nervous system disease DOID:331 0 0.012
large intestine cancer DOID:5672 0 0.012
colon cancer DOID:219 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
intestinal cancer DOID:10155 0 0.012
colorectal cancer DOID:9256 0 0.012
disease of metabolism DOID:0014667 0 0.011
musculoskeletal system disease DOID:17 0 0.011