Mus musculus

0 known processes

Cldn16

claudin 16

(Aliases: claudin-16,PCLN1)

Cldn16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hypotonic response GO:0006971 3 0.978
renal system process GO:0003014 48 0.610
inorganic ion transmembrane transport GO:0098660 234 0.607
ion transmembrane transport GO:0034220 361 0.520
transmembrane transport GO:0055085 412 0.451
developmental maturation GO:0021700 193 0.442
cellular hypotonic response GO:0071476 3 0.416
inorganic cation transmembrane transport GO:0098662 207 0.410
cation transmembrane transport GO:0098655 266 0.403
detection of chemical stimulus involved in sensory perception GO:0050907 10 0.403
cation transport GO:0006812 399 0.374
hyperosmotic response GO:0006972 4 0.365
urinary bladder smooth muscle contraction GO:0014832 5 0.319
smooth muscle contraction involved in micturition GO:0060083 3 0.310
muscle contraction GO:0006936 101 0.279
nitrogen compound transport GO:0071705 271 0.275
response to ph GO:0009268 14 0.209
vasopressin secretion GO:0030103 1 0.202
urinary tract smooth muscle contraction GO:0014848 6 0.173
axonogenesis GO:0007409 274 0.153
response to nutrient levels GO:0031667 109 0.149
regulation of cellular component size GO:0032535 121 0.147
peptide transport GO:0015833 133 0.141
cell junction assembly GO:0034329 52 0.140
Mouse
regulation of anatomical structure size GO:0090066 178 0.133
muscle system process GO:0003012 141 0.133
positive regulation of ion transmembrane transport GO:0034767 24 0.132
regulation of cell size GO:0008361 72 0.127
developmental growth involved in morphogenesis GO:0060560 138 0.125
positive regulation of axon extension GO:0045773 20 0.123
carnitine transport GO:0015879 3 0.122
divalent inorganic cation transport GO:0072511 178 0.122
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.120
cellular homeostasis GO:0019725 240 0.115
inflammatory response GO:0006954 244 0.115
osmosensory signaling pathway GO:0007231 1 0.109
detection of stimulus GO:0051606 84 0.107
regulation of ion transmembrane transport GO:0034765 119 0.107
skin development GO:0043588 220 0.106
Mouse
positive regulation of cell projection organization GO:0031346 95 0.103
calcium ion transmembrane transport GO:0070588 85 0.103
neuron projection extension GO:1990138 64 0.100
multicellular organismal homeostasis GO:0048871 164 0.098
urate transport GO:0015747 1 0.098
acute inflammatory response GO:0002526 41 0.098
cellular chemical homeostasis GO:0055082 215 0.091
regulation of metal ion transport GO:0010959 106 0.091
response to extracellular stimulus GO:0009991 127 0.088
sensory perception GO:0007600 245 0.087
amino acid betaine transport GO:0015838 3 0.084
developmental cell growth GO:0048588 84 0.084
excretion GO:0007588 22 0.082
positive regulation of neuron projection development GO:0010976 79 0.082
regulation of axon extension GO:0030516 43 0.081
regulation of ion transport GO:0043269 215 0.080
positive regulation of ion transport GO:0043270 65 0.079
positive regulation of neuron differentiation GO:0045666 141 0.078
regulation of hormone levels GO:0010817 211 0.077
positive regulation of cell development GO:0010720 237 0.077
regulation of neuron differentiation GO:0045664 281 0.076
positive regulation of calcium ion transport GO:0051928 27 0.075
cation homeostasis GO:0055080 212 0.073
regulation of response to osmotic stress GO:0047484 3 0.072
divalent metal ion transport GO:0070838 172 0.072
cell cell junction assembly GO:0007043 27 0.071
Mouse
sensory perception of chemical stimulus GO:0007606 51 0.070
detection of stimulus involved in sensory perception GO:0050906 44 0.070
carnitine transmembrane transport GO:1902603 3 0.069
hormone secretion GO:0046879 128 0.068
regulation of extent of cell growth GO:0061387 52 0.068
response to osmotic stress GO:0006970 21 0.066
amino acid transmembrane transport GO:0003333 37 0.066
cell cell junction organization GO:0045216 72 0.065
Mouse
purine containing compound metabolic process GO:0072521 311 0.064
micturition GO:0060073 6 0.060
hair cycle phase GO:0044851 16 0.060
sensory perception of mechanical stimulus GO:0050954 107 0.058
cellular divalent inorganic cation homeostasis GO:0072503 127 0.057
cytoplasmic transport GO:0016482 234 0.057
regulation of neuron projection development GO:0010975 169 0.056
cellular ion homeostasis GO:0006873 165 0.053
smooth muscle contraction GO:0006939 44 0.052
diet induced thermogenesis GO:0002024 7 0.051
cell growth GO:0016049 130 0.049
fever generation GO:0001660 7 0.047
chemotaxis GO:0006935 247 0.046
cellular metal ion homeostasis GO:0006875 151 0.046
circulatory system process GO:0003013 197 0.045
regulation of homeostatic process GO:0032844 182 0.045
carnitine metabolic process GO:0009437 7 0.045
cellular ketone metabolic process GO:0042180 84 0.044
response to pain GO:0048265 26 0.043
purine nucleotide metabolic process GO:0006163 302 0.043
cell junction organization GO:0034330 77 0.042
Mouse
regulation of cell projection organization GO:0031344 206 0.042
anion transmembrane transport GO:0098656 71 0.042
regulation of renin secretion into blood stream GO:1900133 4 0.041
nucleotide metabolic process GO:0009117 332 0.040
multicellular organismal response to stress GO:0033555 62 0.039
cellular response to osmotic stress GO:0071470 7 0.037
hair follicle development GO:0001942 85 0.037
hair cycle GO:0042633 90 0.036
heat generation GO:0031649 13 0.036
calcium ion transport GO:0006816 159 0.036
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.035
muscle tissue development GO:0060537 308 0.034
regulation of multicellular organismal metabolic process GO:0044246 14 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.033
biological phase GO:0044848 20 0.033
temperature homeostasis GO:0001659 26 0.033
cytosolic calcium ion homeostasis GO:0051480 70 0.033
positive regulation of transferase activity GO:0051347 167 0.032
cellular response to growth factor stimulus GO:0071363 197 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
small gtpase mediated signal transduction GO:0007264 97 0.032
anatomical structure maturation GO:0071695 49 0.031
blood circulation GO:0008015 195 0.031
cellular amine metabolic process GO:0044106 44 0.031
sodium ion transport GO:0006814 73 0.031
inorganic anion transport GO:0015698 43 0.031
transmission of nerve impulse GO:0019226 76 0.031
Mouse
amine metabolic process GO:0009308 45 0.030
peptide secretion GO:0002790 114 0.030
cytosolic calcium ion transport GO:0060401 48 0.029
cellular response to abiotic stimulus GO:0071214 56 0.029
cellular amino acid metabolic process GO:0006520 103 0.029
response to organonitrogen compound GO:0010243 246 0.029
detection of chemical stimulus GO:0009593 16 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.029
regulation of heart contraction GO:0008016 77 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
molting cycle GO:0042303 90 0.027
divalent inorganic cation homeostasis GO:0072507 138 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
positive regulation of growth GO:0045927 104 0.027
leukocyte differentiation GO:0002521 342 0.027
regulation of lymphocyte activation GO:0051249 240 0.026
protein tetramerization GO:0051262 23 0.026
amino acid transport GO:0006865 61 0.026
cellular calcium ion homeostasis GO:0006874 119 0.026
hydrogen ion transmembrane transport GO:1902600 25 0.026
regulation of membrane potential GO:0042391 192 0.026
Mouse
striated muscle tissue development GO:0014706 293 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
response to dietary excess GO:0002021 18 0.025
renal system development GO:0072001 225 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
amino acid betaine metabolic process GO:0006577 7 0.024
regulation of transferase activity GO:0051338 263 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
calcium ion homeostasis GO:0055074 127 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
regulation of kinase activity GO:0043549 249 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
response to calcium ion GO:0051592 20 0.022
heterocycle catabolic process GO:0046700 280 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
stem cell differentiation GO:0048863 268 0.021
neuronal action potential GO:0019228 54 0.021
Mouse
regulation of calcium ion import GO:0090279 10 0.020
regulation of cell motility GO:2000145 236 0.020
heart process GO:0003015 94 0.020
response to heat GO:0009408 27 0.020
modified amino acid transport GO:0072337 5 0.020
regulation of cell activation GO:0050865 289 0.020
mapk cascade GO:0000165 281 0.020
epidermis development GO:0008544 187 0.019
proton transport GO:0015992 35 0.019
response to growth factor GO:0070848 198 0.019
muscle cell development GO:0055001 133 0.019
positive regulation of nervous system development GO:0051962 221 0.019
anion transport GO:0006820 177 0.019
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.019
fat cell differentiation GO:0045444 160 0.019
glycerolipid metabolic process GO:0046486 122 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
ossification GO:0001503 216 0.018
regulation of cell growth GO:0001558 91 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
cellular response to nutrient levels GO:0031669 64 0.018
regulation of cell cycle GO:0051726 281 0.017
regulation of blood vessel size GO:0050880 56 0.017
multicellular organismal signaling GO:0035637 91 0.017
Mouse
locomotory behavior GO:0007626 195 0.017
ras protein signal transduction GO:0007265 77 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
calcium ion transport into cytosol GO:0060402 48 0.017
protein oligomerization GO:0051259 67 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
epithelial cell proliferation GO:0050673 174 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of response to wounding GO:1903034 189 0.016
cell adhesion GO:0007155 329 0.016
Mouse
response to inorganic substance GO:0010035 96 0.016
cellular response to carbohydrate stimulus GO:0071322 50 0.016
cardiac muscle tissue development GO:0048738 130 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
inter male aggressive behavior GO:0002121 3 0.016
muscle fiber development GO:0048747 76 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
positive regulation of cell growth GO:0030307 33 0.015
regulation of secretion GO:0051046 274 0.015
epithelial cell development GO:0002064 159 0.015
multicellular organismal metabolic process GO:0044236 28 0.015
neuron projection guidance GO:0097485 141 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
cellular response to monosaccharide stimulus GO:0071326 47 0.015
sodium ion transmembrane transport GO:0035725 49 0.015
regulation of organelle organization GO:0033043 289 0.015
regulation of blood pressure GO:0008217 93 0.015
regulation of secretion by cell GO:1903530 249 0.015
glycosyl compound catabolic process GO:1901658 206 0.014
regulation of multi organism process GO:0043900 111 0.014
t cell activation GO:0042110 289 0.014
myeloid leukocyte migration GO:0097529 57 0.014
acute phase response GO:0006953 10 0.014
cognition GO:0050890 149 0.014
stem cell development GO:0048864 219 0.014
homeostasis of number of cells GO:0048872 210 0.014
aromatic compound catabolic process GO:0019439 286 0.014
response to metal ion GO:0010038 47 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
positive regulation of cytokine production GO:0001819 174 0.014
intracellular protein transport GO:0006886 204 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
cardiac muscle contraction GO:0060048 32 0.014
gliogenesis GO:0042063 141 0.014
amide transport GO:0042886 138 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
organic hydroxy compound transport GO:0015850 93 0.013
regulation of cell migration GO:0030334 219 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
single fertilization GO:0007338 82 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of cytokine production GO:0001817 266 0.013
inorganic anion transmembrane transport GO:0098661 29 0.013
cellular response to prostaglandin stimulus GO:0071379 2 0.013
negative regulation of protein modification process GO:0031400 163 0.013
response to acid chemical GO:0001101 111 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of transmembrane transport GO:0034762 128 0.013
small molecule biosynthetic process GO:0044283 132 0.013
bone development GO:0060348 120 0.013
midgut development GO:0007494 4 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
c21 steroid hormone biosynthetic process GO:0006700 3 0.013
macromolecule catabolic process GO:0009057 281 0.013
heart contraction GO:0060047 93 0.013
positive regulation of thymocyte migration GO:2000412 2 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.012
ensheathment of neurons GO:0007272 76 0.012
Mouse
cellular response to starvation GO:0009267 57 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
negative regulation of hormone metabolic process GO:0032351 4 0.012
response to vitamin d GO:0033280 3 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
mesenchyme development GO:0060485 152 0.012
regulation of protein kinase activity GO:0045859 232 0.012
tissue homeostasis GO:0001894 115 0.012
kidney development GO:0001822 213 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
regulation of blood circulation GO:1903522 93 0.012
multicellular organism growth GO:0035264 161 0.012
regulation of system process GO:0044057 200 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
digestive system development GO:0055123 200 0.012
positive regulation of vasoconstriction GO:0045907 4 0.012
androgen biosynthetic process GO:0006702 4 0.012
neuron migration GO:0001764 122 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
organic acid transport GO:0015849 101 0.012
carbohydrate homeostasis GO:0033500 128 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
single organism cell adhesion GO:0098602 156 0.012
regulation of cellular response to stress GO:0080135 159 0.011
synaptic transmission GO:0007268 329 0.011
cellular response to heat GO:0034605 15 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
fertilization GO:0009566 127 0.011
cellular protein complex assembly GO:0043623 116 0.011
heart morphogenesis GO:0003007 178 0.011
av node cell to bundle of his cell communication GO:0086067 2 0.011
membrane organization GO:0061024 245 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
regulation of actin filament based process GO:0032970 99 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
rho protein signal transduction GO:0007266 32 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
respiratory system development GO:0060541 190 0.010
placenta development GO:0001890 140 0.010
gland development GO:0048732 330 0.010
regulation of action potential GO:0098900 4 0.010
leukocyte chemotaxis GO:0030595 69 0.010
neurotransmitter transport GO:0006836 76 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
striated muscle cell development GO:0055002 125 0.010
organic anion transport GO:0015711 137 0.010
ammonia homeostasis GO:0097272 1 0.010
response to light stimulus GO:0009416 135 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010

Cldn16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.013