Mus musculus

8 known processes

Cldn6

claudin 6

(Aliases: AL024037)

Cldn6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ morphogenesis GO:0090596 242 0.588
neural tube development GO:0021915 160 0.522
gland development GO:0048732 330 0.522
limb morphogenesis GO:0035108 149 0.447
axonogenesis GO:0007409 274 0.442
embryonic epithelial tube formation GO:0001838 130 0.372
epithelial tube morphogenesis GO:0060562 303 0.370
blastocyst development GO:0001824 80 0.345
primary neural tube formation GO:0014020 95 0.344
endomembrane system organization GO:0010256 147 0.329
appendage morphogenesis GO:0035107 149 0.327
mapk cascade GO:0000165 281 0.325
placenta development GO:0001890 140 0.323
embryonic placenta development GO:0001892 98 0.311
cell fate commitment GO:0045165 210 0.310
embryonic limb morphogenesis GO:0030326 126 0.296
stem cell development GO:0048864 219 0.295
skin development GO:0043588 220 0.283
Mouse
appendage development GO:0048736 166 0.282
spermatogenesis GO:0007283 284 0.273
Mouse
limb development GO:0060173 166 0.262
axon guidance GO:0007411 141 0.251
embryonic digit morphogenesis GO:0042733 56 0.247
inner ear morphogenesis GO:0042472 101 0.245
ameboidal type cell migration GO:0001667 128 0.245
embryonic organ morphogenesis GO:0048562 276 0.234
blood vessel morphogenesis GO:0048514 285 0.232
astrocyte fate commitment GO:0060018 4 0.228
kidney development GO:0001822 213 0.226
camera type eye development GO:0043010 266 0.224
embryonic appendage morphogenesis GO:0035113 126 0.221
cell migration involved in gastrulation GO:0042074 13 0.212
ear development GO:0043583 200 0.212
neuron projection guidance GO:0097485 141 0.211
cell differentiation in spinal cord GO:0021515 53 0.211
embryonic skeletal system development GO:0048706 120 0.198
stem cell differentiation GO:0048863 268 0.196
positive regulation of nervous system development GO:0051962 221 0.190
paraxial mesodermal cell fate commitment GO:0048343 2 0.190
determination of left right symmetry GO:0007368 80 0.188
endodermal cell fate specification GO:0001714 4 0.184
neural tube closure GO:0001843 90 0.183
urogenital system development GO:0001655 261 0.181
lung development GO:0030324 164 0.179
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.179
negative regulation of cell development GO:0010721 169 0.174
somatic stem cell maintenance GO:0035019 47 0.169
polarity specification of proximal distal axis GO:0010085 2 0.168
skeletal system development GO:0001501 356 0.166
digestive system development GO:0055123 200 0.163
hindbrain development GO:0030902 128 0.162
morphogenesis of a polarized epithelium GO:0001738 37 0.162
ear morphogenesis GO:0042471 118 0.161
tube formation GO:0035148 140 0.158
somite development GO:0061053 81 0.157
regulation of organ morphogenesis GO:2000027 144 0.156
neuron migration GO:0001764 122 0.155
stem cell proliferation GO:0072089 117 0.153
establishment of endothelial blood brain barrier GO:0014045 3 0.151
epithelial tube formation GO:0072175 130 0.150
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.149
regionalization GO:0003002 337 0.147
regulation of body fluid levels GO:0050878 162 0.147
Mouse
hormone secretion GO:0046879 128 0.146
cellular amino acid metabolic process GO:0006520 103 0.146
neural tube formation GO:0001841 108 0.146
response to organonitrogen compound GO:0010243 246 0.145
positive regulation of epithelial cell proliferation GO:0050679 68 0.145
positive regulation of protein modification process GO:0031401 299 0.145
organ growth GO:0035265 117 0.145
stem cell maintenance GO:0019827 130 0.145
cardiac chamber morphogenesis GO:0003206 93 0.145
amide transport GO:0042886 138 0.145
male gamete generation GO:0048232 285 0.144
Mouse
embryonic heart tube development GO:0035050 65 0.144
multicellular organism growth GO:0035264 161 0.143
nitrogen compound transport GO:0071705 271 0.139
bmp signaling pathway GO:0030509 93 0.138
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.138
spinal cord development GO:0021510 81 0.137
forebrain development GO:0030900 302 0.135
cellular homeostasis GO:0019725 240 0.134
central nervous system neuron differentiation GO:0021953 162 0.133
hypophysis morphogenesis GO:0048850 3 0.133
positive regulation of neuron differentiation GO:0045666 141 0.133
renal vesicle induction GO:0072034 3 0.129
mesendoderm development GO:0048382 3 0.128
renal system development GO:0072001 225 0.128
tendon cell differentiation GO:0035990 4 0.126
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.125
locomotory behavior GO:0007626 195 0.125
respiratory system development GO:0060541 190 0.125
establishment of organelle localization GO:0051656 122 0.121
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.120
embryonic camera type eye development GO:0031076 36 0.119
artery development GO:0060840 53 0.116
positive regulation of keratinocyte proliferation GO:0010838 4 0.115
forebrain morphogenesis GO:0048853 17 0.115
cartilage development GO:0051216 140 0.114
left lung development GO:0060459 4 0.113
mesoderm formation GO:0001707 62 0.111
cell adhesion GO:0007155 329 0.111
Mouse
regulation of muscle tissue development GO:1901861 97 0.111
regulation of peptide hormone secretion GO:0090276 75 0.110
positive regulation of stem cell proliferation GO:2000648 59 0.110
cardiac septum development GO:0003279 59 0.109
blastocyst formation GO:0001825 33 0.109
regulation of cellular amino acid metabolic process GO:0006521 5 0.108
wnt signaling pathway GO:0016055 188 0.107
retina morphogenesis in camera type eye GO:0060042 45 0.107
cardiocyte differentiation GO:0035051 87 0.106
cell type specific apoptotic process GO:0097285 268 0.104
cellular response to growth factor stimulus GO:0071363 197 0.104
chondrocyte differentiation GO:0002062 72 0.104
neural precursor cell proliferation GO:0061351 121 0.103
regulation of cell migration GO:0030334 219 0.103
response to nutrient levels GO:0031667 109 0.102
positive regulation of mapk cascade GO:0043410 170 0.102
metencephalon development GO:0022037 89 0.102
trophectodermal cell differentiation GO:0001829 21 0.101
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.100
skeletal system morphogenesis GO:0048705 203 0.100
ossification GO:0001503 216 0.100
embryonic eye morphogenesis GO:0048048 29 0.100
somitogenesis GO:0001756 69 0.099
tendon formation GO:0035992 4 0.099
germ cell development GO:0007281 185 0.097
regulation of nucleotide metabolic process GO:0006140 169 0.097
regulation of neuron apoptotic process GO:0043523 122 0.095
molting cycle GO:0042303 90 0.095
negative regulation of prostatic bud formation GO:0060686 4 0.095
insulin secretion GO:0030073 89 0.094
ventricular septum morphogenesis GO:0060412 27 0.094
mesenchyme development GO:0060485 152 0.093
kidney mesenchyme morphogenesis GO:0072131 4 0.093
regulation of system process GO:0044057 200 0.093
gastrulation GO:0007369 116 0.093
developmental growth involved in morphogenesis GO:0060560 138 0.093
chemotaxis GO:0006935 247 0.091
peptide secretion GO:0002790 114 0.091
myotube differentiation GO:0014902 105 0.091
retina development in camera type eye GO:0060041 119 0.091
carbohydrate homeostasis GO:0033500 128 0.090
morphogenesis of embryonic epithelium GO:0016331 159 0.089
axis elongation involved in somitogenesis GO:0090245 4 0.089
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.089
cardiac right atrium morphogenesis GO:0003213 3 0.088
positive regulation of growth GO:0045927 104 0.088
formation of primary germ layer GO:0001704 77 0.087
peptide hormone secretion GO:0030072 109 0.087
subpallium neuron fate commitment GO:0060163 2 0.087
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.086
trachea cartilage morphogenesis GO:0060535 4 0.085
positive regulation of cell development GO:0010720 237 0.085
cardiac septum morphogenesis GO:0060411 46 0.085
regulation of homeostatic process GO:0032844 182 0.084
myotube cell development GO:0014904 60 0.084
protein modification by small protein conjugation or removal GO:0070647 207 0.083
muscle cell differentiation GO:0042692 261 0.083
negative regulation of wnt signaling pathway GO:0030178 73 0.083
neuroblast proliferation GO:0007405 49 0.082
regulation of anagen GO:0051884 1 0.082
cardiac ventricle development GO:0003231 83 0.081
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.080
respiratory tube development GO:0030323 167 0.080
oviduct development GO:0060066 3 0.079
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.079
cell cell junction organization GO:0045216 72 0.078
cellular macromolecule catabolic process GO:0044265 206 0.078
cochlea morphogenesis GO:0090103 22 0.078
establishment of tissue polarity GO:0007164 28 0.077
posttranscriptional regulation of gene expression GO:0010608 155 0.077
determination of heart left right asymmetry GO:0061371 48 0.077
peptide transport GO:0015833 133 0.077
epidermis development GO:0008544 187 0.076
mesoderm morphogenesis GO:0048332 64 0.076
paraxial mesodermal cell differentiation GO:0048342 2 0.076
developmental maturation GO:0021700 193 0.075
regulation of stem cell proliferation GO:0072091 78 0.075
regulation of heart morphogenesis GO:2000826 22 0.075
plasma membrane organization GO:0007009 90 0.075
body morphogenesis GO:0010171 45 0.074
regulation of bmp signaling pathway GO:0030510 60 0.074
mesenchymal cell differentiation GO:0048762 107 0.073
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.073
lung induction GO:0060492 3 0.073
exocrine system development GO:0035272 45 0.071
regulation of renin secretion into blood stream GO:1900133 4 0.071
macromolecule catabolic process GO:0009057 281 0.071
regulation of hormone levels GO:0010817 211 0.071
digestive tract development GO:0048565 190 0.071
regulation of cartilage development GO:0061035 44 0.071
embryonic heart tube morphogenesis GO:0003143 51 0.071
epithelial cell development GO:0002064 159 0.070
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.070
cochlea development GO:0090102 35 0.069
cellular response to hormone stimulus GO:0032870 150 0.068
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.068
mitotic cell cycle GO:0000278 195 0.068
protein catabolic process GO:0030163 221 0.068
regulation of epidermis development GO:0045682 33 0.067
myeloid cell differentiation GO:0030099 233 0.067
response to extracellular stimulus GO:0009991 127 0.067
single organism nuclear import GO:1902593 95 0.067
tube closure GO:0060606 91 0.067
spemann organizer formation GO:0060061 2 0.067
non canonical wnt signaling pathway GO:0035567 33 0.066
axial mesodermal cell fate commitment GO:0048322 1 0.066
cell fate determination GO:0001709 32 0.066
leukocyte differentiation GO:0002521 342 0.066
translation GO:0006412 93 0.066
regulation of ossification GO:0030278 112 0.065
nucleoside phosphate metabolic process GO:0006753 338 0.065
hormone metabolic process GO:0042445 86 0.065
regulation of peptide secretion GO:0002791 77 0.065
cellular chemical homeostasis GO:0055082 215 0.065
segmentation GO:0035282 93 0.065
circulatory system process GO:0003013 197 0.065
transmission of nerve impulse GO:0019226 76 0.065
Mouse
olfactory bulb development GO:0021772 30 0.064
pyramidal neuron migration GO:0021852 1 0.064
negative regulation of mesodermal cell fate specification GO:0042662 3 0.063
purine ribonucleoside catabolic process GO:0046130 205 0.063
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.063
cellular response to organonitrogen compound GO:0071417 145 0.063
cell junction organization GO:0034330 77 0.062
glucose homeostasis GO:0042593 128 0.062
positive regulation of synaptic plasticity GO:0031915 4 0.062
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.062
reflex GO:0060004 22 0.062
skeletal muscle fiber development GO:0048741 58 0.062
prostate gland development GO:0030850 48 0.061
endochondral bone morphogenesis GO:0060350 50 0.060
nephron tubule morphogenesis GO:0072078 68 0.060
positive regulation of cell migration GO:0030335 109 0.060
hindlimb morphogenesis GO:0035137 42 0.060
organelle localization GO:0051640 179 0.060
regulation of mapk cascade GO:0043408 248 0.059
regulation of protein localization GO:0032880 231 0.059
regulation of organelle organization GO:0033043 289 0.059
formation of radial glial scaffolds GO:0021943 4 0.059
cardiac chamber development GO:0003205 108 0.058
regulation of cell motility GO:2000145 236 0.058
gonad development GO:0008406 141 0.058
endoderm development GO:0007492 45 0.058
modification dependent macromolecule catabolic process GO:0043632 133 0.058
cell maturation GO:0048469 127 0.057
spinal cord association neuron differentiation GO:0021527 14 0.057
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.057
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.057
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.057
regulation of embryonic development GO:0045995 71 0.057
purine ribonucleotide metabolic process GO:0009150 290 0.056
striated muscle cell development GO:0055002 125 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 0.056
t cell differentiation in thymus GO:0033077 77 0.056
female somatic sex determination GO:0019101 1 0.055
digestive tract morphogenesis GO:0048546 147 0.055
outflow tract morphogenesis GO:0003151 53 0.055
positive regulation of protein phosphorylation GO:0001934 242 0.055
cell growth GO:0016049 130 0.055
protein ubiquitination GO:0016567 171 0.055
extracellular matrix organization GO:0030198 147 0.055
angiogenesis GO:0001525 201 0.055
cell division GO:0051301 120 0.055
regulation of peptide transport GO:0090087 91 0.054
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.054
ribose phosphate metabolic process GO:0019693 291 0.054
sensory perception of mechanical stimulus GO:0050954 107 0.054
regulation of actin filament based process GO:0032970 99 0.054
mesenchyme morphogenesis GO:0072132 32 0.054
striated muscle tissue development GO:0014706 293 0.054
floor plate morphogenesis GO:0033505 3 0.054
cellular response to starvation GO:0009267 57 0.053
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.053
dna metabolic process GO:0006259 303 0.053
oxidation reduction process GO:0055114 342 0.053
synapse organization GO:0050808 125 0.053
left lung morphogenesis GO:0060460 3 0.052
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.052
purine containing compound catabolic process GO:0072523 213 0.052
positive regulation of cell adhesion GO:0045785 80 0.052
t cell differentiation GO:0030217 174 0.052
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.052
neurotransmitter transport GO:0006836 76 0.052
hexose metabolic process GO:0019318 98 0.051
axial mesoderm development GO:0048318 8 0.051
multicellular organismal water homeostasis GO:0050891 23 0.051
Mouse
ventricular septum development GO:0003281 42 0.050
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.050
regulation of water loss via skin GO:0033561 16 0.050
Mouse
septum primum development GO:0003284 4 0.050
asymmetric neuroblast division GO:0055059 1 0.050
histone methylation GO:0016571 71 0.050
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.050
response to acid chemical GO:0001101 111 0.049
bone morphogenesis GO:0060349 78 0.049
canonical wnt signaling pathway GO:0060070 130 0.049
gliogenesis GO:0042063 141 0.049
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.048
cell differentiation involved in embryonic placenta development GO:0060706 26 0.048
cardiac atrium morphogenesis GO:0003209 23 0.048
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.048
morphogenesis of a branching structure GO:0001763 203 0.048
paraxial mesoderm development GO:0048339 18 0.048
renal outer medulla development GO:0072054 2 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.048
metanephros development GO:0001656 79 0.048
regulation of neuroblast proliferation GO:1902692 27 0.047
cellular response to hexose stimulus GO:0071331 47 0.047
regulation of cell adhesion GO:0030155 154 0.047
biomineral tissue development GO:0031214 64 0.047
response to growth factor GO:0070848 198 0.047
syncytium formation by plasma membrane fusion GO:0000768 42 0.046
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.046
endoderm formation GO:0001706 20 0.046
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.046
cellular ketone metabolic process GO:0042180 84 0.046
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.046
morphogenesis of an epithelial sheet GO:0002011 27 0.046
nucleoside triphosphate catabolic process GO:0009143 205 0.046
multicellular organismal homeostasis GO:0048871 164 0.045
actin cytoskeleton organization GO:0030036 220 0.045
renal tubule morphogenesis GO:0061333 72 0.045
regulation of cell size GO:0008361 72 0.045
regulation of wnt signaling pathway GO:0030111 123 0.045
peptidyl amino acid modification GO:0018193 336 0.045
renal inner medulla development GO:0072053 3 0.045
somatotropin secreting cell differentiation GO:0060126 4 0.045
spongiotrophoblast layer development GO:0060712 15 0.044
cerebral cortex development GO:0021987 86 0.044
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.044
positive regulation of cellular component biogenesis GO:0044089 94 0.043
mesodermal cell migration GO:0008078 4 0.043
developmental cell growth GO:0048588 84 0.043
head morphogenesis GO:0060323 34 0.043
cardiac muscle cell proliferation GO:0060038 31 0.043
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.043
vesicle localization GO:0051648 86 0.043
negative regulation of fat cell differentiation GO:0045599 36 0.043
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.043
modification dependent protein catabolic process GO:0019941 133 0.043
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.043
water homeostasis GO:0030104 27 0.042
Mouse
forebrain generation of neurons GO:0021872 63 0.042
odontogenesis of dentin containing tooth GO:0042475 66 0.042
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.042
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.042
hippocampus development GO:0021766 52 0.042
regulation of endodermal cell differentiation GO:1903224 2 0.042
macromolecule methylation GO:0043414 120 0.042
ion transmembrane transport GO:0034220 361 0.042
regulation of cellular response to stress GO:0080135 159 0.042
primitive streak formation GO:0090009 10 0.042
negative regulation of molecular function GO:0044092 258 0.042
regulation of organ growth GO:0046620 61 0.042
axial mesoderm formation GO:0048320 3 0.042
positive regulation of tendon cell differentiation GO:2001051 1 0.041
regulation of microvillus assembly GO:0032534 3 0.041
tissue regeneration GO:0042246 22 0.041
branching involved in ureteric bud morphogenesis GO:0001658 56 0.041
forebrain neuron fate commitment GO:0021877 13 0.041
methylation GO:0032259 134 0.041
telencephalon development GO:0021537 186 0.040
nephrogenic mesenchyme development GO:0072076 3 0.040
neuronal action potential GO:0019228 54 0.040
Mouse
regulation of hormone secretion GO:0046883 88 0.040
kidney rudiment formation GO:0072003 3 0.040
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.040
regulation of purine nucleotide metabolic process GO:1900542 169 0.040
mesoderm development GO:0007498 100 0.040
negative regulation of neuron death GO:1901215 98 0.040
neural crest cell differentiation GO:0014033 54 0.040
nucleocytoplasmic transport GO:0006913 139 0.040
paramesonephric duct development GO:0061205 3 0.039
regulation of jnk cascade GO:0046328 62 0.039
connective tissue development GO:0061448 179 0.039
cellular response to carbohydrate stimulus GO:0071322 50 0.039
trophectodermal cellular morphogenesis GO:0001831 3 0.039
cardiac epithelial to mesenchymal transition GO:0060317 18 0.039
regulation of secretion by cell GO:1903530 249 0.039
neural tube patterning GO:0021532 43 0.039
midgut development GO:0007494 4 0.039
forebrain neuron differentiation GO:0021879 52 0.039
cellular response to monosaccharide stimulus GO:0071326 47 0.039
lens development in camera type eye GO:0002088 62 0.039
negative regulation of nervous system development GO:0051961 156 0.038
hindbrain morphogenesis GO:0021575 46 0.038
positive regulation of cell cycle GO:0045787 92 0.038
forebrain radial glial cell differentiation GO:0021861 4 0.038
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.038
regulation of cell cycle GO:0051726 281 0.037
palate development GO:0060021 76 0.037
mesonephric tubule development GO:0072164 94 0.037
multi multicellular organism process GO:0044706 109 0.037
regulation of endodermal cell fate specification GO:0042663 2 0.037
positive regulation of anagen GO:0051885 1 0.037
cytoplasmic transport GO:0016482 234 0.037
regulation of establishment of protein localization GO:0070201 181 0.037
anion transport GO:0006820 177 0.037
forelimb morphogenesis GO:0035136 40 0.037
central nervous system neuron development GO:0021954 67 0.037
mammary gland morphogenesis GO:0060443 54 0.037
skeletal muscle organ development GO:0060538 163 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.037
hair follicle development GO:0001942 85 0.036
transition metal ion homeostasis GO:0055076 54 0.036
mammary gland duct morphogenesis GO:0060603 38 0.036
regulation of neuron death GO:1901214 134 0.036
negative regulation of cholesterol transport GO:0032375 4 0.036
wound healing GO:0042060 157 0.036
rhythmic process GO:0048511 174 0.036
mesangial cell differentiation GO:0072007 4 0.036
membrane organization GO:0061024 245 0.036
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.036
ensheathment of neurons GO:0007272 76 0.036
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.036
av node cell to bundle of his cell communication GO:0086067 2 0.036
regulation of chondrocyte differentiation GO:0032330 33 0.035
maintenance of cell number GO:0098727 3 0.035
carbohydrate metabolic process GO:0005975 230 0.035
regulation of cell cycle process GO:0010564 160 0.035
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.035
central nervous system vasculogenesis GO:0022009 3 0.035
positive regulation of neuroblast proliferation GO:0002052 19 0.035
negative regulation of gastrulation GO:2000542 3 0.035
establishment of organ orientation GO:0048561 1 0.035
visual perception GO:0007601 52 0.035
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.034
roof plate formation GO:0021509 1 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
sensory perception of sound GO:0007605 97 0.034
sclerotome development GO:0061056 4 0.034
mesonephric duct morphogenesis GO:0072180 4 0.034
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.034
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.034
protein modification by small protein conjugation GO:0032446 187 0.034
epithelial cell proliferation GO:0050673 174 0.034
prostate gland stromal morphogenesis GO:0060741 2 0.034
ubiquitin dependent protein catabolic process GO:0006511 129 0.034
regulation of hydrolase activity GO:0051336 246 0.033
action potential GO:0001508 78 0.033
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.033
response to amino acid GO:0043200 37 0.033
regulation of neuron differentiation GO:0045664 281 0.033
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.033
extracellular structure organization GO:0043062 148 0.033
negative regulation of neuron apoptotic process GO:0043524 92 0.033
nuclear division GO:0000280 158 0.033
mitral valve morphogenesis GO:0003183 4 0.033
amine metabolic process GO:0009308 45 0.033
neuron death GO:0070997 154 0.033
response to starvation GO:0042594 65 0.033
negative regulation of glucokinase activity GO:0033132 4 0.033
glucose metabolic process GO:0006006 92 0.033
response to monosaccharide GO:0034284 67 0.033
gastrulation with mouth forming second GO:0001702 29 0.033
negative regulation of cellular component organization GO:0051129 194 0.032
regulation of heart growth GO:0060420 31 0.032
establishment of anatomical structure orientation GO:0048560 1 0.032
labyrinthine layer morphogenesis GO:0060713 21 0.032
myoblast differentiation GO:0045445 52 0.032
regulation of biomineral tissue development GO:0070167 33 0.032
midbrain hindbrain boundary maturation GO:0021732 1 0.032
development of primary female sexual characteristics GO:0046545 73 0.032
lateral line system development GO:0048925 1 0.032
pallium development GO:0021543 120 0.032
metanephric mesenchyme morphogenesis GO:0072133 4 0.032
positive regulation of neural precursor cell proliferation GO:2000179 42 0.031
limbic system development GO:0021761 72 0.031
foramen ovale closure GO:0035922 1 0.031
embryonic forelimb morphogenesis GO:0035115 32 0.031
positive regulation of cell cycle process GO:0090068 61 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.031
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.031
sensory system development GO:0048880 3 0.031
sensory perception GO:0007600 245 0.031
primary prostatic bud elongation GO:0060516 2 0.031
notch signaling pathway GO:0007219 71 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
regulation of organ formation GO:0003156 34 0.031
nucleotide catabolic process GO:0009166 217 0.031
metanephric loop of henle development GO:0072236 4 0.031
branching morphogenesis of an epithelial tube GO:0048754 159 0.030
regulation of stem cell maintenance GO:2000036 17 0.030
multicellular organismal signaling GO:0035637 91 0.030
Mouse
synaptic transmission GO:0007268 329 0.030
cellular protein catabolic process GO:0044257 155 0.030
ventral midline development GO:0007418 4 0.030
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
cation homeostasis GO:0055080 212 0.030
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.030
mesonephric duct formation GO:0072181 2 0.030
negative regulation of cell proliferation GO:0008285 296 0.030

Cldn6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
musculoskeletal system disease DOID:17 0 0.038
disease of cellular proliferation DOID:14566 0 0.030