Mus musculus

0 known processes

Cma2

chymase 2, mast cell

(Aliases: Mcp10)

Cma2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response to bacterium GO:0042742 119 0.157
defense response to other organism GO:0098542 197 0.133
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.130
interspecies interaction between organisms GO:0044419 83 0.089
defense response to gram positive bacterium GO:0050830 50 0.088
immune effector process GO:0002252 321 0.087
negative regulation of immune system process GO:0002683 209 0.087
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.085
disruption by host of symbiont cells GO:0051852 11 0.073
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.072
interaction with symbiont GO:0051702 14 0.072
cellular response to cytokine stimulus GO:0071345 189 0.068
cell killing GO:0001906 67 0.068
innate immune response GO:0045087 157 0.066
regulation of angiotensin levels in blood GO:0002002 4 0.065
disruption of cells of other organism GO:0044364 13 0.064
protein processing GO:0016485 163 0.063
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.060
skin development GO:0043588 220 0.059
regulation of membrane potential GO:0042391 192 0.058
cytokine mediated signaling pathway GO:0019221 115 0.055
regulation of angiotensin metabolic process GO:0060177 4 0.052
spermatogenesis GO:0007283 284 0.051
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.050
gland development GO:0048732 330 0.050
regulation of hydrolase activity GO:0051336 246 0.049
intracellular protein transport GO:0006886 204 0.049
multicellular organismal signaling GO:0035637 91 0.048
cellular response to extracellular stimulus GO:0031668 81 0.047
male gamete generation GO:0048232 285 0.046
neutrophil mediated killing of bacterium GO:0070944 6 0.046
modification by host of symbiont morphology or physiology GO:0051851 12 0.045
positive regulation of apoptotic process GO:0043065 217 0.045
killing by host of symbiont cells GO:0051873 11 0.045
locomotory behavior GO:0007626 195 0.044
negative regulation of lymphocyte activation GO:0051250 91 0.043
developmental maturation GO:0021700 193 0.042
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.042
maintenance of location GO:0051235 89 0.041
response to organic cyclic compound GO:0014070 198 0.041
neuronal action potential GO:0019228 54 0.039
aromatic compound catabolic process GO:0019439 286 0.039
heterocycle catabolic process GO:0046700 280 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
regulation of protein localization GO:0032880 231 0.036
regulation of cell activation GO:0050865 289 0.036
angiogenesis GO:0001525 201 0.034
regulation of endocytosis GO:0030100 69 0.034
lymphocyte mediated immunity GO:0002449 139 0.033
response to molecule of bacterial origin GO:0002237 143 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
cell maturation GO:0048469 127 0.032
endocytosis GO:0006897 168 0.032
killing of cells of other organism GO:0031640 13 0.031
regulation of striated muscle cell differentiation GO:0051153 81 0.031
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.031
regulation of defense response to bacterium GO:1900424 3 0.030
cytokine production GO:0001816 319 0.030
protein maturation GO:0051604 176 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
neutrophil mediated immunity GO:0002446 19 0.029
membrane organization GO:0061024 245 0.028
natural killer cell activation GO:0030101 44 0.028
leukocyte mediated cytotoxicity GO:0001909 62 0.028
cellular response to insulin stimulus GO:0032869 78 0.028
negative regulation of t cell activation GO:0050868 65 0.027
negative regulation of multi organism process GO:0043901 68 0.027
t helper 2 cell cytokine production GO:0035745 4 0.027
protein localization to organelle GO:0033365 185 0.027
viral process GO:0016032 41 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.026
modification of morphology or physiology of other organism GO:0035821 18 0.026
peptidyl tyrosine modification GO:0018212 145 0.025
single organism cell adhesion GO:0098602 156 0.025
regulation of defense response GO:0031347 233 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
response to lipopolysaccharide GO:0032496 128 0.025
neutrophil mediated killing of symbiont cell GO:0070943 8 0.025
regulation of cellular response to stress GO:0080135 159 0.025
apoptotic signaling pathway GO:0097190 306 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
regulation of vesicle mediated transport GO:0060627 139 0.024
response to oxidative stress GO:0006979 123 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
positive regulation of cytokine production GO:0001819 174 0.023
epidermis development GO:0008544 187 0.023
muscle fiber development GO:0048747 76 0.023
positive regulation of defense response GO:0031349 124 0.023
cytoplasmic transport GO:0016482 234 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
nucleotide metabolic process GO:0009117 332 0.022
regulation of transferase activity GO:0051338 263 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.022
germ cell development GO:0007281 185 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
wound healing GO:0042060 157 0.022
negative regulation of cell activation GO:0050866 111 0.021
antibacterial peptide biosynthetic process GO:0002780 2 0.021
steroid metabolic process GO:0008202 119 0.021
cellular response to biotic stimulus GO:0071216 92 0.021
cellular amine metabolic process GO:0044106 44 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.021
purine containing compound catabolic process GO:0072523 213 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
cellular ketone metabolic process GO:0042180 84 0.021
amine metabolic process GO:0009308 45 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
regulation of multi organism process GO:0043900 111 0.020
positive regulation of protein modification process GO:0031401 299 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
protein targeting GO:0006605 143 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
positive regulation of innate immune response GO:0045089 80 0.019
receptor mediated endocytosis GO:0006898 51 0.019
inflammatory response GO:0006954 244 0.019
spermatid development GO:0007286 108 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
development of primary sexual characteristics GO:0045137 143 0.019
compound eye development GO:0048749 1 0.019
leukocyte apoptotic process GO:0071887 71 0.019
regulation of response to wounding GO:1903034 189 0.019
activation of immune response GO:0002253 138 0.018
defense response to gram negative bacterium GO:0050829 28 0.018
cellular response to lipid GO:0071396 145 0.018
regulation of organelle organization GO:0033043 289 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
regulation of protein transport GO:0051223 163 0.018
lipid biosynthetic process GO:0008610 179 0.018
regulation of body fluid levels GO:0050878 162 0.018
chemotaxis GO:0006935 247 0.017
epithelial tube formation GO:0072175 130 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of kinase activity GO:0043549 249 0.017
adaptive immune response GO:0002250 155 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
regulation of cell migration GO:0030334 219 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
progesterone metabolic process GO:0042448 4 0.016
neural tube formation GO:0001841 108 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
regulation of skeletal muscle fiber development GO:0048742 36 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
antibacterial humoral response GO:0019731 8 0.016
jnk cascade GO:0007254 72 0.016
regulation of leukocyte apoptotic process GO:2000106 56 0.016
stress activated mapk cascade GO:0051403 80 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
regulation of lipid biosynthetic process GO:0046890 54 0.015
positive regulation of defense response to bacterium GO:1900426 1 0.015
interleukin 12 secretion GO:0072610 3 0.015
cellularization GO:0007349 1 0.015
muscle tissue development GO:0060537 308 0.015
neural tube development GO:0021915 160 0.015
hair cycle GO:0042633 90 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
regulation of thymocyte migration GO:2000410 2 0.015
rna interference GO:0016246 2 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
myotube differentiation GO:0014902 105 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of stress activated mapk cascade GO:0032872 69 0.015
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.014
regulation of innate immune response GO:0045088 91 0.014
spermatid differentiation GO:0048515 115 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
leukocyte differentiation GO:0002521 342 0.014
regulation of epidermal cell differentiation GO:0045604 21 0.014
positive regulation of jak stat cascade GO:0046427 22 0.014
regulation of keratinocyte differentiation GO:0045616 11 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
activation of innate immune response GO:0002218 56 0.014
positive regulation of response to wounding GO:1903036 66 0.014
myotube cell development GO:0014904 60 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
response to steroid hormone GO:0048545 56 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
mrna metabolic process GO:0016071 84 0.014
glycoprotein metabolic process GO:0009100 116 0.014
regulation of lymphocyte apoptotic process GO:0070228 41 0.014
nuclear import GO:0051170 95 0.014
hair follicle development GO:0001942 85 0.014
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of protein processing GO:0070613 96 0.013
defense response to virus GO:0051607 68 0.013
tube formation GO:0035148 140 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
muscle cell differentiation GO:0042692 261 0.013
regulation of monocyte chemotaxis GO:0090025 3 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
blood vessel morphogenesis GO:0048514 285 0.013
coenzyme metabolic process GO:0006732 52 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
phagocytosis GO:0006909 66 0.012
protein import GO:0017038 101 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
positive regulation of phospholipase activity GO:0010518 3 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
immune response activating signal transduction GO:0002757 116 0.012
regulation of myotube differentiation GO:0010830 62 0.012
regulation of t cell activation GO:0050863 170 0.012
t cell activation GO:0042110 289 0.012
regulation of microvillus assembly GO:0032534 3 0.012
pattern recognition receptor signaling pathway GO:0002221 47 0.012
regulation of cell cycle GO:0051726 281 0.012
regulation of t helper 2 cell cytokine production GO:2000551 3 0.012
axon ensheathment GO:0008366 76 0.012
striated muscle tissue development GO:0014706 293 0.012
regulation of hormone levels GO:0010817 211 0.012
myeloid leukocyte migration GO:0097529 57 0.012
regulation of cell motility GO:2000145 236 0.012
cellular response to food GO:0071240 1 0.012
transmission of nerve impulse GO:0019226 76 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
peptide transport GO:0015833 133 0.011
skeletal muscle organ development GO:0060538 163 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
negative regulation of interleukin 5 production GO:0032714 4 0.011
molting cycle GO:0042303 90 0.011
response to stilbenoid GO:0035634 22 0.011
action potential GO:0001508 78 0.011
lipid localization GO:0010876 126 0.011
regulation of antimicrobial humoral response GO:0002759 3 0.011
cellular amino acid metabolic process GO:0006520 103 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
ras protein signal transduction GO:0007265 77 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
response to reactive oxygen species GO:0000302 56 0.011
maintenance of protein location in nucleus GO:0051457 2 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
translation GO:0006412 93 0.011
response to extracellular stimulus GO:0009991 127 0.011
lipid storage GO:0019915 36 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
negative regulation of growth GO:0045926 99 0.011
cellular response to peptide GO:1901653 92 0.010
organophosphate catabolic process GO:0046434 232 0.010
t cell apoptotic process GO:0070231 39 0.010
negative regulation of interleukin 13 production GO:0032696 2 0.010
leukocyte chemotaxis GO:0030595 69 0.010
cell type specific apoptotic process GO:0097285 268 0.010
positive regulation of striated muscle cell differentiation GO:0051155 35 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
t cell mediated immunity GO:0002456 50 0.010
coagulation GO:0050817 78 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
lymphocyte apoptotic process GO:0070227 54 0.010
female sex differentiation GO:0046660 84 0.010
stress activated protein kinase signaling cascade GO:0031098 81 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
mucopolysaccharide metabolic process GO:1903510 25 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
mitotic cell cycle GO:0000278 195 0.010

Cma2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.024
inherited metabolic disorder DOID:655 0 0.024
bone disease DOID:0080001 0 0.018
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
central nervous system disease DOID:331 0 0.016
nervous system disease DOID:863 0 0.016
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011