Mus musculus

135 known processes

Col3a1

collagen, type III, alpha 1

(Aliases: MMS10-W,KIAA4231,AW550625,Ms10w,mKIAA4231,Col3a-1)

Col3a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular structure organization GO:0043062 148 0.999
extracellular matrix organization GO:0030198 147 0.996
protein heterotrimerization GO:0070208 8 0.977
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.976
proteoglycan metabolic process GO:0006029 38 0.974
Mouse
negative regulation of cell substrate adhesion GO:0010812 16 0.901
Mouse
aorta smooth muscle tissue morphogenesis GO:0060414 2 0.894
protein trimerization GO:0070206 13 0.891
Mouse
connective tissue development GO:0061448 179 0.868
Mouse
response to amino acid GO:0043200 37 0.863
limb bud formation GO:0060174 10 0.853
Mouse
aorta morphogenesis GO:0035909 22 0.815
negative regulation of tooth mineralization GO:0070171 1 0.814
cellular response to growth factor stimulus GO:0071363 197 0.788
Human Mouse
cell substrate adhesion GO:0031589 130 0.744
Human Mouse
bone trabecula formation GO:0060346 9 0.733
Mouse
skeletal system development GO:0001501 356 0.714
Mouse Rat
regulation of cell adhesion GO:0030155 154 0.709
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.705
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.702
Mouse
collagen fibril organization GO:0030199 32 0.697
response to bmp GO:0071772 14 0.690
Mouse
regulation of tooth mineralization GO:0070170 2 0.679
cartilage condensation GO:0001502 18 0.671
Mouse
bone development GO:0060348 120 0.665
Mouse
rho protein signal transduction GO:0007266 32 0.654
cartilage development GO:0051216 140 0.637
Mouse
extracellular fibril organization GO:0043206 2 0.635
Human
positive regulation of rho protein signal transduction GO:0035025 7 0.625
negative regulation of vasculature development GO:1901343 26 0.593
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.583
Mouse
chondrocyte differentiation GO:0002062 72 0.582
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.581
Mouse
forebrain development GO:0030900 302 0.577
regulation of cell substrate adhesion GO:0010810 73 0.534
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.532
Mouse
cell adhesion GO:0007155 329 0.529
Human Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.528
Mouse
protein heterooligomerization GO:0051291 14 0.527
Mouse
protein oligomerization GO:0051259 67 0.526
Mouse
negative regulation of cell migration GO:0030336 59 0.522
endochondral bone morphogenesis GO:0060350 50 0.510
Mouse
response to epidermal growth factor GO:0070849 4 0.503
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.483
Mouse
endoderm development GO:0007492 45 0.474
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.462
Mouse
neuron migration GO:0001764 122 0.448
muscle tissue development GO:0060537 308 0.447
negative regulation of cell adhesion GO:0007162 45 0.440
Mouse
cellular response to acid chemical GO:0071229 68 0.440
negative regulation of blood vessel morphogenesis GO:2000181 25 0.435
replacement ossification GO:0036075 26 0.431
Mouse
cerebral cortex development GO:0021987 86 0.431
artery development GO:0060840 53 0.408
signal transduction in absence of ligand GO:0038034 55 0.407
Mouse
regulation of neuron migration GO:2001222 22 0.406
head morphogenesis GO:0060323 34 0.405
Mouse
sensory organ morphogenesis GO:0090596 242 0.398
Mouse
tissue homeostasis GO:0001894 115 0.374
Mouse
limb development GO:0060173 166 0.371
Mouse
sensory perception of sound GO:0007605 97 0.368
Mouse
response to organonitrogen compound GO:0010243 246 0.362
embryonic organ morphogenesis GO:0048562 276 0.361
Mouse
muscle tissue morphogenesis GO:0060415 53 0.359
positive regulation of ras protein signal transduction GO:0046579 13 0.352
ear morphogenesis GO:0042471 118 0.346
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.342
negative regulation of nervous system development GO:0051961 156 0.338
cellular response to organonitrogen compound GO:0071417 145 0.333
negative regulation of cell motility GO:2000146 61 0.325
endoderm formation GO:0001706 20 0.323
face morphogenesis GO:0060325 29 0.314
Mouse
bone morphogenesis GO:0060349 78 0.311
Mouse
cell matrix adhesion GO:0007160 68 0.307
Human Mouse
skeletal system morphogenesis GO:0048705 203 0.305
Mouse
anatomical structure homeostasis GO:0060249 145 0.301
Mouse
notochord development GO:0030903 20 0.295
Mouse
trabecula morphogenesis GO:0061383 40 0.294
Mouse
response to acid chemical GO:0001101 111 0.291
cardiac ventricle morphogenesis GO:0003208 50 0.291
Mouse
direct ossification GO:0036072 5 0.283
Mouse
response to oxidative stress GO:0006979 123 0.282
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.269
Mouse
response to catecholamine GO:0071869 4 0.268
response to organic cyclic compound GO:0014070 198 0.264
fibril organization GO:0097435 2 0.260
Human
ossification GO:0001503 216 0.258
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.249
Mouse
retinal blood vessel morphogenesis GO:0061304 3 0.246
negative regulation of neuron migration GO:2001223 6 0.230
inner ear morphogenesis GO:0042472 101 0.228
Mouse
appendage morphogenesis GO:0035107 149 0.224
Mouse
response to growth factor GO:0070848 198 0.223
Human Mouse
otic vesicle development GO:0071599 14 0.221
Mouse
negative regulation of angiogenesis GO:0016525 25 0.219
synaptic transmission cholinergic GO:0007271 7 0.202
trabecula formation GO:0060343 24 0.201
Mouse
molting cycle GO:0042303 90 0.201
multicellular organismal homeostasis GO:0048871 164 0.200
Mouse
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.199
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan GO:0019800 8 0.192
bone trabecula morphogenesis GO:0061430 12 0.188
Mouse
cellular response to bmp stimulus GO:0071773 14 0.187
Mouse
regulation of proteolysis GO:0030162 164 0.186
aorta development GO:0035904 23 0.183
ventricular cardiac muscle tissue development GO:0003229 38 0.181
Mouse
heart morphogenesis GO:0003007 178 0.176
Mouse
appendage development GO:0048736 166 0.172
Mouse
urogenital system development GO:0001655 261 0.157
positive regulation of cell migration GO:0030335 109 0.151
striated muscle tissue development GO:0014706 293 0.146
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.141
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.139
Human
blood vessel morphogenesis GO:0048514 285 0.131
wound healing GO:0042060 157 0.127
Human
protein maturation GO:0051604 176 0.125
insulin processing GO:0030070 2 0.125
digestive system development GO:0055123 200 0.123
negative regulation of gastrulation GO:2000542 3 0.118
negative regulation of cell development GO:0010721 169 0.116
formation of primary germ layer GO:0001704 77 0.114
embryonic skeletal system development GO:0048706 120 0.113
Mouse
regulation of endodermal cell differentiation GO:1903224 2 0.098
regulation of transmission of nerve impulse GO:0051969 1 0.092
response to transforming growth factor beta GO:0071559 88 0.088
Human
pallium development GO:0021543 120 0.087
regulation of cell motility GO:2000145 236 0.086
regulation of endothelial cell apoptotic process GO:2000351 9 0.085
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.083
Human
embryonic skeletal system morphogenesis GO:0048704 91 0.082
Mouse
regulation of fatty acid oxidation GO:0046320 10 0.082
regulation of apoptotic signaling pathway GO:2001233 197 0.081
Mouse
ras protein signal transduction GO:0007265 77 0.078
limb morphogenesis GO:0035108 149 0.077
Mouse
peripheral nervous system axon regeneration GO:0014012 2 0.074
cellular response to mechanical stimulus GO:0071260 7 0.074
Mouse
respiratory tube development GO:0030323 167 0.070
negative regulation of cell proliferation involved in contact inhibition GO:0060244 3 0.070
nephron development GO:0072006 109 0.069
cellular response to abiotic stimulus GO:0071214 56 0.069
Mouse
angiogenesis GO:0001525 201 0.067
digestive tract morphogenesis GO:0048546 147 0.066
response to retinoic acid GO:0032526 56 0.066
negative regulation of protein activation cascade GO:2000258 3 0.064
cellular response to lipid GO:0071396 145 0.064
tendon development GO:0035989 6 0.064
Mouse
sensory perception of mechanical stimulus GO:0050954 107 0.064
Mouse
endodermal cell differentiation GO:0035987 14 0.061
response to thyroid hormone GO:0097066 2 0.059
neuromuscular process GO:0050905 99 0.059
digestive tract development GO:0048565 190 0.058
body morphogenesis GO:0010171 45 0.058
Mouse
positive regulation of cell substrate adhesion GO:0010811 47 0.057
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.055
cardiac ventricle development GO:0003231 83 0.054
Mouse
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.053
negative regulation of cell proliferation GO:0008285 296 0.052
biomineral tissue development GO:0031214 64 0.051
face development GO:0060324 38 0.050
Mouse
protein hydroxylation GO:0018126 4 0.050
telencephalon development GO:0021537 186 0.050
sensory perception GO:0007600 245 0.049
Mouse
ear development GO:0043583 200 0.049
Mouse
negative regulation of ossification GO:0030279 49 0.048
mucopolysaccharide metabolic process GO:1903510 25 0.048
negative regulation of odontogenesis GO:0042483 3 0.047
gastrulation GO:0007369 116 0.046
regulation of cell migration GO:0030334 219 0.046
regulation of androgen receptor signaling pathway GO:0060765 3 0.045
growth plate cartilage development GO:0003417 14 0.043
positive regulation of hydrolase activity GO:0051345 148 0.043
negative regulation of complement activation GO:0045916 3 0.042
regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 1 0.039
regulation of blood pressure GO:0008217 93 0.039
fatty acid metabolic process GO:0006631 121 0.039
regulation of chondrocyte differentiation GO:0032330 33 0.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.039
response to monosaccharide GO:0034284 67 0.038
stem cell differentiation GO:0048863 268 0.037
regulation of biomineral tissue development GO:0070167 33 0.035
glycoprotein metabolic process GO:0009100 116 0.034
Mouse
regulation of cell size GO:0008361 72 0.034
cardiac muscle cell development GO:0055013 39 0.033
negative regulation of embryonic development GO:0045992 22 0.033
cellular response to nitric oxide GO:0071732 4 0.032
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.032
regulation of translation GO:0006417 71 0.032
chondrocyte development GO:0002063 24 0.031
Mouse
skeletal muscle organ development GO:0060538 163 0.031
engulfment of apoptotic cell GO:0043652 3 0.031
negative regulation of endodermal cell differentiation GO:1903225 1 0.030
regulation of removal of superoxide radicals GO:2000121 4 0.030
smooth muscle tissue development GO:0048745 22 0.030
regulation of sphingolipid biosynthetic process GO:0090153 1 0.030
regulation of angiogenesis GO:0045765 81 0.029
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.029
regulation of body fluid levels GO:0050878 162 0.029
lung development GO:0030324 164 0.029
neuromuscular process controlling balance GO:0050885 59 0.029
regulation of reactive oxygen species metabolic process GO:2000377 40 0.029
response to monoamine GO:0071867 4 0.028
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.028
cell growth involved in cardiac muscle cell development GO:0061049 3 0.027
physiological cardiac muscle hypertrophy GO:0003301 3 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
acylglycerol metabolic process GO:0006639 55 0.027
response to alcohol GO:0097305 48 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
positive regulation of cell adhesion GO:0045785 80 0.026
cellular lipid metabolic process GO:0044255 323 0.026
regulation of neuron projection development GO:0010975 169 0.026
protein processing GO:0016485 163 0.026
termination of rna polymerase i transcription GO:0006363 2 0.026
neutral lipid metabolic process GO:0006638 57 0.026
peptide cross linking GO:0018149 10 0.025
Human
response to extracellular stimulus GO:0009991 127 0.025
cellular response to vitamin GO:0071295 2 0.025
oxidation reduction process GO:0055114 342 0.024
hair follicle morphogenesis GO:0031069 29 0.023
collagen biosynthetic process GO:0032964 7 0.023
sulfur compound metabolic process GO:0006790 100 0.023
developmental cell growth GO:0048588 84 0.023
cardiac chamber development GO:0003205 108 0.022
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.022
homeostasis of number of cells GO:0048872 210 0.022
chondroitin sulfate metabolic process GO:0030204 17 0.022
aminoglycan metabolic process GO:0006022 34 0.022
regulation of ceramide biosynthetic process GO:2000303 1 0.022
positive regulation of cell development GO:0010720 237 0.021
negative regulation of macrophage chemotaxis GO:0010760 1 0.021
response to peptide GO:1901652 136 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
odontogenesis GO:0042476 78 0.020
regulation of immunological synapse formation GO:2000520 2 0.020
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.020
response to lipopolysaccharide GO:0032496 128 0.020
response to peptide hormone GO:0043434 127 0.020
sequestering of bmp in extracellular matrix GO:0035582 3 0.020
plasma membrane organization GO:0007009 90 0.020
respiratory system development GO:0060541 190 0.020
translation GO:0006412 93 0.020
antimicrobial peptide biosynthetic process GO:0002777 2 0.020
intussusceptive angiogenesis GO:0002041 2 0.019
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.019
cardiac cell development GO:0055006 41 0.019
mesangial cell differentiation GO:0072007 4 0.019
epidermis development GO:0008544 187 0.019
cellular response to superoxide GO:0071451 14 0.018
oviduct development GO:0060066 3 0.018
cardiocyte differentiation GO:0035051 87 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
telencephalon cell migration GO:0022029 55 0.018
long chain fatty acid import GO:0044539 2 0.018
antibacterial humoral response GO:0019731 8 0.017
camera type eye development GO:0043010 266 0.017
regulation of ras protein signal transduction GO:0046578 114 0.017
cellular response to retinoic acid GO:0071300 25 0.017
regulation of map kinase activity GO:0043405 120 0.017
regulation of fibrinolysis GO:0051917 1 0.017
regulation of hormone levels GO:0010817 211 0.017
palate development GO:0060021 76 0.017
Mouse
positive regulation of secretion GO:0051047 130 0.017
peptidyl serine modification GO:0018209 83 0.016
synaptic transmission GO:0007268 329 0.016
hair cycle GO:0042633 90 0.016
renal system development GO:0072001 225 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
notochord cell differentiation GO:0060034 1 0.016
positive regulation of bone remodeling GO:0046852 13 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.015
elastic fiber assembly GO:0048251 4 0.015
synaptic transmission glutamatergic GO:0035249 36 0.015
ameboidal type cell migration GO:0001667 128 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
clathrin coat assembly GO:0048268 2 0.015
hormone secretion GO:0046879 128 0.014
hair follicle development GO:0001942 85 0.014
regulation of peptidase activity GO:0052547 96 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
cardiac muscle tissue development GO:0048738 130 0.014
Mouse
positive regulation of programmed cell death GO:0043068 218 0.014
tooth mineralization GO:0034505 9 0.014
glycosaminoglycan metabolic process GO:0030203 34 0.014
positive regulation of proteolysis GO:0045862 85 0.014
nuclear import GO:0051170 95 0.014
triglyceride metabolic process GO:0006641 51 0.014
bone resorption GO:0045453 38 0.013
positive regulation of hormone secretion GO:0046887 38 0.013
regulation of secretion GO:0051046 274 0.013
synapse organization GO:0050808 125 0.013
protein catabolic process GO:0030163 221 0.013
fibrinolysis GO:0042730 3 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of jun kinase activity GO:0043506 40 0.013
forebrain cell migration GO:0021885 58 0.013
sensory system development GO:0048880 3 0.013
lateral line system development GO:0048925 1 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.012
Human
positive regulation of response to wounding GO:1903036 66 0.012
cell growth GO:0016049 130 0.012
protein autoprocessing GO:0016540 2 0.012
cellular response to epidermal growth factor stimulus GO:0071364 4 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
negative regulation of cell adhesion involved in substrate bound cell migration GO:0006933 3 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
collagen metabolic process GO:0032963 17 0.012
integrin biosynthetic process GO:0045112 1 0.012
response to steroid hormone GO:0048545 56 0.012
negative regulation of biomineral tissue development GO:0070168 11 0.012
regulation of ossification GO:0030278 112 0.011
negative regulation of icosanoid secretion GO:0032304 1 0.011
negative regulation of fibrinolysis GO:0051918 1 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
blood circulation GO:0008015 195 0.011
positive regulation of axon extension GO:0045773 20 0.011
epithelial cell proliferation GO:0050673 174 0.011
multicellular organismal macromolecule metabolic process GO:0044259 19 0.011
spermatogenesis GO:0007283 284 0.011
fat cell differentiation GO:0045444 160 0.011
negative regulation of fatty acid transport GO:2000192 1 0.010
antimicrobial peptide secretion GO:0002776 1 0.010
macromolecule catabolic process GO:0009057 281 0.010
skin morphogenesis GO:0043589 38 0.010
golgi localization GO:0051645 4 0.010
astrocyte fate commitment GO:0060018 4 0.010
negative regulation of phospholipase activity GO:0010519 4 0.010
substrate adhesion dependent cell spreading GO:0034446 30 0.010
regulation of embryonic development GO:0045995 71 0.010
positive regulation of neuron projection regeneration GO:0070572 2 0.010

Col3a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.989
Human
musculoskeletal system disease DOID:17 0 0.989
Human
connective tissue disease DOID:65 0 0.989
Human
collagen disease DOID:854 0 0.837
Human
myopathy DOID:423 0 0.820
muscular disease DOID:0080000 0 0.820
muscle tissue disease DOID:66 0 0.820
congenital muscular dystrophy DOID:0050557 0 0.751
muscular dystrophy DOID:9884 0 0.751
ehlers danlos syndrome DOID:13359 0 0.439
Human
bone disease DOID:0080001 0 0.437
bone development disease DOID:0080006 0 0.372
osteochondrodysplasia DOID:2256 0 0.295
bone remodeling disease DOID:0080005 0 0.237
bone resorption disease DOID:0080011 0 0.237
osteogenesis imperfecta DOID:12347 0 0.212
osteoporosis DOID:11476 0 0.199
heart disease DOID:114 0 0.013
cardiovascular system disease DOID:1287 0 0.013