Mus musculus

0 known processes

Col6a3

collagen, type VI, alpha 3

(Aliases: Col6a-3,AI507288)

Col6a3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
extracellular structure organization GO:0043062 148 0.998
Mouse
extracellular matrix organization GO:0030198 147 0.977
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.899
cell adhesion GO:0007155 329 0.842
Mouse
fibril organization GO:0097435 2 0.649
collagen fibril organization GO:0030199 32 0.560
bone development GO:0060348 120 0.514
response to amino acid GO:0043200 37 0.486
cellular response to growth factor stimulus GO:0071363 197 0.468
extrinsic apoptotic signaling pathway GO:0097191 126 0.457
cartilage condensation GO:0001502 18 0.404
cell substrate adhesion GO:0031589 130 0.395
Mouse
regulation of cell adhesion GO:0030155 154 0.392
Mouse
response to growth factor GO:0070848 198 0.386
cell aggregation GO:0098743 18 0.382
skeletal system development GO:0001501 356 0.374
nephron development GO:0072006 109 0.372
regulation of cell substrate adhesion GO:0010810 73 0.348
Mouse
ossification GO:0001503 216 0.345
respiratory tube development GO:0030323 167 0.333
aorta smooth muscle tissue morphogenesis GO:0060414 2 0.325
cardiac muscle tissue development GO:0048738 130 0.316
connective tissue development GO:0061448 179 0.302
protein heterotrimerization GO:0070208 8 0.287
cellular response to acid chemical GO:0071229 68 0.274
extracellular fibril organization GO:0043206 2 0.269
cell matrix adhesion GO:0007160 68 0.266
negative regulation of cell adhesion GO:0007162 45 0.257
trabecula formation GO:0060343 24 0.242
blood vessel morphogenesis GO:0048514 285 0.238
chondrocyte differentiation GO:0002062 72 0.227
digestive system development GO:0055123 200 0.221
regulation of neuron migration GO:2001222 22 0.216
endoderm formation GO:0001706 20 0.200
anatomical structure homeostasis GO:0060249 145 0.198
wound healing GO:0042060 157 0.189
male gamete generation GO:0048232 285 0.189
proteoglycan metabolic process GO:0006029 38 0.185
renal system development GO:0072001 225 0.183
tissue homeostasis GO:0001894 115 0.180
protein trimerization GO:0070206 13 0.171
bone trabecula formation GO:0060346 9 0.157
negative regulation of cell substrate adhesion GO:0010812 16 0.152
physiological cardiac muscle hypertrophy GO:0003301 3 0.148
endochondral bone morphogenesis GO:0060350 50 0.142
urogenital system development GO:0001655 261 0.139
cell type specific apoptotic process GO:0097285 268 0.137
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.137
protein hydroxylation GO:0018126 4 0.134
response to organonitrogen compound GO:0010243 246 0.134
protein heterooligomerization GO:0051291 14 0.133
negative regulation of cell development GO:0010721 169 0.132
digestive tract development GO:0048565 190 0.132
regulation of cell motility GO:2000145 236 0.128
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.127
embryonic organ morphogenesis GO:0048562 276 0.124
lung development GO:0030324 164 0.124
cerebral cortex development GO:0021987 86 0.122
striated muscle tissue development GO:0014706 293 0.122
spermatogenesis GO:0007283 284 0.121
response to bmp GO:0071772 14 0.116
regulation of system process GO:0044057 200 0.106
single organism cell adhesion GO:0098602 156 0.106
face development GO:0060324 38 0.104
cartilage development GO:0051216 140 0.104
angiogenesis GO:0001525 201 0.102
cardiac ventricle morphogenesis GO:0003208 50 0.101
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.099
regulation of removal of superoxide radicals GO:2000121 4 0.099
limb bud formation GO:0060174 10 0.099
positive regulation of peptidase activity GO:0010952 49 0.096
trabecula morphogenesis GO:0061383 40 0.095
limb development GO:0060173 166 0.093
heart morphogenesis GO:0003007 178 0.093
muscle tissue morphogenesis GO:0060415 53 0.092
removal of superoxide radicals GO:0019430 12 0.090
limb morphogenesis GO:0035108 149 0.088
cardiac muscle cell development GO:0055013 39 0.086
response to organic cyclic compound GO:0014070 198 0.085
skeletal system morphogenesis GO:0048705 203 0.083
negative regulation of vasculature development GO:1901343 26 0.083
digestive tract morphogenesis GO:0048546 147 0.083
mesonephric tubule morphogenesis GO:0072171 63 0.083
head morphogenesis GO:0060323 34 0.081
multicellular organismal homeostasis GO:0048871 164 0.080
cell growth involved in cardiac muscle cell development GO:0061049 3 0.078
signal transduction in absence of ligand GO:0038034 55 0.075
appendage morphogenesis GO:0035107 149 0.075
intussusceptive angiogenesis GO:0002041 2 0.073
embryonic skeletal system development GO:0048706 120 0.072
cardiac chamber morphogenesis GO:0003206 93 0.071
forebrain development GO:0030900 302 0.071
negative regulation of nervous system development GO:0051961 156 0.070
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.070
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.068
cellular response to organonitrogen compound GO:0071417 145 0.065
positive regulation of cell migration GO:0030335 109 0.065
regulation of proteolysis GO:0030162 164 0.064
elastic fiber assembly GO:0048251 4 0.064
artery development GO:0060840 53 0.064
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.063
negative regulation of apoptotic signaling pathway GO:2001234 104 0.062
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.062
regulation of ossification GO:0030278 112 0.062
ventricular cardiac muscle tissue development GO:0003229 38 0.059
aorta development GO:0035904 23 0.059
peripheral nervous system axon regeneration GO:0014012 2 0.059
neuron migration GO:0001764 122 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
synaptic transmission GO:0007268 329 0.057
biomineral tissue development GO:0031214 64 0.056
negative regulation of blood vessel morphogenesis GO:2000181 25 0.056
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.055
negative regulation of tooth mineralization GO:0070171 1 0.055
embryonic skeletal system morphogenesis GO:0048704 91 0.054
small gtpase mediated signal transduction GO:0007264 97 0.051
protein oligomerization GO:0051259 67 0.051
bone morphogenesis GO:0060349 78 0.050
regionalization GO:0003002 337 0.050
negative regulation of angiogenesis GO:0016525 25 0.050
muscle tissue development GO:0060537 308 0.050
regulation of macrophage migration inhibitory factor signaling pathway GO:2000446 1 0.049
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.048
retinal blood vessel morphogenesis GO:0061304 3 0.048
sensory perception of sound GO:0007605 97 0.048
Mouse
formation of primary germ layer GO:0001704 77 0.047
notochord development GO:0030903 20 0.045
telencephalon development GO:0021537 186 0.044
regulation of endothelial cell apoptotic process GO:2000351 9 0.044
chondrocyte development GO:0002063 24 0.044
negative regulation of phospholipase activity GO:0010519 4 0.044
replacement ossification GO:0036075 26 0.044
organ growth GO:0035265 117 0.044
epithelial tube morphogenesis GO:0060562 303 0.043
regulation of tooth mineralization GO:0070170 2 0.043
camera type eye development GO:0043010 266 0.042
negative regulation of neuron migration GO:2001223 6 0.042
positive regulation of bone remodeling GO:0046852 13 0.041
response to catecholamine GO:0071869 4 0.041
cellular response to bmp stimulus GO:0071773 14 0.039
glycoprotein metabolic process GO:0009100 116 0.039
negative regulation of cell proliferation GO:0008285 296 0.038
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.037
regulation of cell migration GO:0030334 219 0.037
response to transforming growth factor beta GO:0071559 88 0.037
endothelial cell apoptotic process GO:0072577 9 0.037
cardiac muscle tissue morphogenesis GO:0055008 44 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.036
regulation of angiogenesis GO:0045765 81 0.036
sensory organ morphogenesis GO:0090596 242 0.036
astrocyte fate commitment GO:0060018 4 0.036
branching morphogenesis of an epithelial tube GO:0048754 159 0.035
bone trabecula morphogenesis GO:0061430 12 0.035
kidney development GO:0001822 213 0.034
rho protein signal transduction GO:0007266 32 0.033
growth plate cartilage development GO:0003417 14 0.033
ameboidal type cell migration GO:0001667 128 0.033
endochondral bone growth GO:0003416 19 0.033
gastrulation GO:0007369 116 0.032
intestinal epithelial structure maintenance GO:0060729 4 0.032
oviduct development GO:0060066 3 0.032
endoderm development GO:0007492 45 0.032
sensory perception GO:0007600 245 0.032
Mouse
response to inorganic substance GO:0010035 96 0.031
ras protein signal transduction GO:0007265 77 0.031
regulation of muscle system process GO:0090257 80 0.030
cardiac cell development GO:0055006 41 0.030
pallium development GO:0021543 120 0.030
cellular ketone metabolic process GO:0042180 84 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.028
direct ossification GO:0036072 5 0.028
clathrin coat assembly GO:0048268 2 0.028
ear development GO:0043583 200 0.028
regulation of biomineral tissue development GO:0070167 33 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
positive regulation of proteolysis GO:0045862 85 0.027
skeletal muscle organ development GO:0060538 163 0.027
physiological muscle hypertrophy GO:0003298 3 0.026
regulation of transmission of nerve impulse GO:0051969 1 0.026
cellular response to abiotic stimulus GO:0071214 56 0.026
axonogenesis GO:0007409 274 0.026
regulation of peptidase activity GO:0052547 96 0.026
face morphogenesis GO:0060325 29 0.026
tendon development GO:0035989 6 0.025
positive regulation of cell motility GO:2000147 116 0.025
developmental maturation GO:0021700 193 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
positive regulation of cell substrate adhesion GO:0010811 47 0.025
Mouse
cellular response to superoxide GO:0071451 14 0.025
mesenchyme development GO:0060485 152 0.025
negative regulation of cell migration GO:0030336 59 0.024
organelle fission GO:0048285 170 0.024
peptidyl amino acid modification GO:0018193 336 0.024
ear morphogenesis GO:0042471 118 0.024
skin development GO:0043588 220 0.024
negative regulation of gastrulation GO:2000542 3 0.024
response to acid chemical GO:0001101 111 0.023
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.023
blood circulation GO:0008015 195 0.023
regulation of neuron projection development GO:0010975 169 0.022
sensory perception of mechanical stimulus GO:0050954 107 0.022
Mouse
endodermal cell differentiation GO:0035987 14 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
spinal cord development GO:0021510 81 0.022
regulation of endodermal cell differentiation GO:1903224 2 0.022
respiratory system development GO:0060541 190 0.022
negative regulation of lipoprotein lipase activity GO:0051005 1 0.022
macromolecule catabolic process GO:0009057 281 0.022
extracellular matrix assembly GO:0085029 12 0.021
regulation of chondrocyte differentiation GO:0032330 33 0.021
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.021
inner ear morphogenesis GO:0042472 101 0.021
developmental cell growth GO:0048588 84 0.021
cellular amino acid metabolic process GO:0006520 103 0.020
response to thyroid hormone GO:0097066 2 0.020
cellular response to mechanical stimulus GO:0071260 7 0.020
muscle cell differentiation GO:0042692 261 0.020
long term synaptic potentiation GO:0060291 25 0.020
regulation of cartilage development GO:0061035 44 0.020
otic vesicle development GO:0071599 14 0.020
aorta morphogenesis GO:0035909 22 0.020
positive regulation of growth GO:0045927 104 0.020
negative regulation of cartilage development GO:0061037 17 0.020
cellular response to external stimulus GO:0071496 88 0.019
muscle cell development GO:0055001 133 0.019
regulation of blood coagulation GO:0030193 28 0.019
positive regulation of rho protein signal transduction GO:0035025 7 0.019
kidney morphogenesis GO:0060993 83 0.019
regulation of organelle organization GO:0033043 289 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
smooth muscle tissue development GO:0048745 22 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
neuromuscular process GO:0050905 99 0.019
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.018
regulation of rho protein signal transduction GO:0035023 71 0.018
endomembrane system organization GO:0010256 147 0.018
cellular response to epidermal growth factor stimulus GO:0071364 4 0.018
response to epidermal growth factor GO:0070849 4 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of macrophage chemotaxis GO:0010760 1 0.017
appendage development GO:0048736 166 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
Mouse
negative regulation of neuron projection regeneration GO:0070571 3 0.017
plasma membrane organization GO:0007009 90 0.016
oxidation reduction process GO:0055114 342 0.016
multicellular organism growth GO:0035264 161 0.016
mitotic cell cycle GO:0000278 195 0.016
early endosome to late endosome transport GO:0045022 2 0.016
foramen ovale closure GO:0035922 1 0.016
homeostasis of number of cells GO:0048872 210 0.016
bone resorption GO:0045453 38 0.016
retina development in camera type eye GO:0060041 119 0.016
regulation of sphingolipid biosynthetic process GO:0090153 1 0.016
germ cell development GO:0007281 185 0.015
peptidyl proline hydroxylation GO:0019511 3 0.015
palate development GO:0060021 76 0.015
cellular response to estradiol stimulus GO:0071392 6 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
neuromuscular process controlling balance GO:0050885 59 0.015
synaptic transmission cholinergic GO:0007271 7 0.015
negative regulation of ossification GO:0030279 49 0.015
regulation of vesicle mediated transport GO:0060627 139 0.014
positive regulation of cell cycle GO:0045787 92 0.014
nuclear division GO:0000280 158 0.014
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.014
positive regulation of nervous system development GO:0051962 221 0.014
response to radiation GO:0009314 165 0.014
substrate adhesion dependent cell spreading GO:0034446 30 0.014
regulation of muscle adaptation GO:0043502 31 0.014
gland development GO:0048732 330 0.014
positive regulation of axon extension GO:0045773 20 0.014
positive regulation of cell projection organization GO:0031346 95 0.013
cardiac chamber development GO:0003205 108 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
locomotory behavior GO:0007626 195 0.013
organelle assembly GO:0070925 177 0.013
negative regulation of response to wounding GO:1903035 77 0.013
somitogenesis GO:0001756 69 0.013
multi multicellular organism process GO:0044706 109 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
defense response to bacterium GO:0042742 119 0.013
Mouse
antimicrobial peptide secretion GO:0002776 1 0.013
protein catabolic process GO:0030163 221 0.013
odontogenesis GO:0042476 78 0.013
covalent chromatin modification GO:0016569 163 0.012
synaptic transmission glutamatergic GO:0035249 36 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
multicellular organismal response to stress GO:0033555 62 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
regulation of exit from mitosis GO:0007096 1 0.012
gonad development GO:0008406 141 0.012
prostate gland morphogenesis GO:0060512 32 0.012
negative regulation of epithelial cell proliferation GO:0050680 64 0.012
salivary gland development GO:0007431 37 0.012
cellular response to thyroid hormone stimulus GO:0097067 1 0.012
anatomical structure maturation GO:0071695 49 0.012
response to monoamine GO:0071867 4 0.011
regulation of map kinase activity GO:0043405 120 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
regulation of synaptic plasticity GO:0048167 87 0.011
negative regulation of endodermal cell differentiation GO:1903225 1 0.011
negative regulation of growth GO:0045926 99 0.011
apoptotic signaling pathway GO:0097190 306 0.011
cellular protein catabolic process GO:0044257 155 0.011
regulation of cellular response to stress GO:0080135 159 0.011
sequestering of bmp in extracellular matrix GO:0035582 3 0.011
regulation of response to cytokine stimulus GO:0060759 23 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
metal ion homeostasis GO:0055065 189 0.011
epithelial cell proliferation GO:0050673 174 0.011
establishment of monopolar cell polarity GO:0061162 8 0.011
positive regulation of cell development GO:0010720 237 0.010
regulation of androgen receptor signaling pathway GO:0060765 3 0.010
synapse organization GO:0050808 125 0.010
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.010
negative regulation of cell motility GO:2000146 61 0.010
glucose homeostasis GO:0042593 128 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010

Col6a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.966
Human
musculoskeletal system disease DOID:17 0 0.966
Human
myopathy DOID:423 0 0.939
Human
muscular disease DOID:0080000 0 0.939
Human
muscle tissue disease DOID:66 0 0.939
Human
congenital muscular dystrophy DOID:0050557 0 0.582
Human
muscular dystrophy DOID:9884 0 0.582
Human
collagen disease DOID:854 0 0.260
connective tissue disease DOID:65 0 0.260
bone remodeling disease DOID:0080005 0 0.132
bone disease DOID:0080001 0 0.132
heart disease DOID:114 0 0.071
cardiomyopathy DOID:0050700 0 0.071
dilated cardiomyopathy DOID:12930 0 0.071
intrinsic cardiomyopathy DOID:0060036 0 0.071
cardiovascular system disease DOID:1287 0 0.071
ehlers danlos syndrome DOID:13359 0 0.069
osteochondrodysplasia DOID:2256 0 0.051
osteogenesis imperfecta DOID:12347 0 0.051
bone development disease DOID:0080006 0 0.051
osteoporosis DOID:11476 0 0.033
bone resorption disease DOID:0080011 0 0.033
nervous system disease DOID:863 0 0.028
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
eye disease DOID:5614 0 0.023
retinal disease DOID:5679 0 0.019
glaucoma DOID:1686 0 0.017
retinal degeneration DOID:8466 0 0.017