Mus musculus

0 known processes

Copa

coatomer protein complex subunit alpha

(Aliases: xenin,AU040324)

Copa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intra golgi vesicle mediated transport GO:0006891 1 0.477
cytoplasmic transport GO:0016482 234 0.414
Yeast
localization within membrane GO:0051668 4 0.254
copii coated vesicle budding GO:0090114 2 0.193
vesicle organization GO:0016050 60 0.126
endomembrane system organization GO:0010256 147 0.117
golgi vesicle transport GO:0048193 30 0.097
Yeast
metal ion homeostasis GO:0055065 189 0.088
cation homeostasis GO:0055080 212 0.083
small gtpase mediated signal transduction GO:0007264 97 0.079
membrane organization GO:0061024 245 0.078
intracellular protein transport GO:0006886 204 0.075
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.073
Yeast
ras protein signal transduction GO:0007265 77 0.064
macromolecule catabolic process GO:0009057 281 0.059
endocytosis GO:0006897 168 0.058
Fly
inorganic ion transmembrane transport GO:0098660 234 0.057
cellular amino acid metabolic process GO:0006520 103 0.050
spermatogenesis GO:0007283 284 0.049
nucleotide metabolic process GO:0009117 332 0.049
divalent inorganic cation homeostasis GO:0072507 138 0.048
modification dependent macromolecule catabolic process GO:0043632 133 0.046
cellular amine metabolic process GO:0044106 44 0.045
protein catabolic process GO:0030163 221 0.045
er to golgi vesicle mediated transport GO:0006888 11 0.044
Yeast
cation transport GO:0006812 399 0.044
ion transmembrane transport GO:0034220 361 0.044
rho protein signal transduction GO:0007266 32 0.042
male gamete generation GO:0048232 285 0.041
establishment of endothelial blood brain barrier GO:0014045 3 0.039
t cell activation GO:0042110 289 0.038
purine nucleotide metabolic process GO:0006163 302 0.036
germ cell development GO:0007281 185 0.036
protein targeting to vacuole GO:0006623 3 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
amine metabolic process GO:0009308 45 0.035
dna metabolic process GO:0006259 303 0.035
cellular chemical homeostasis GO:0055082 215 0.034
actin cytoskeleton organization GO:0030036 220 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.033
maintenance of location GO:0051235 89 0.033
Fly
cation transmembrane transport GO:0098655 266 0.032
negative regulation of molecular function GO:0044092 258 0.032
compound eye development GO:0048749 1 0.032
engulfment of apoptotic cell GO:0043652 3 0.032
ribonucleoside catabolic process GO:0042454 206 0.031
leukocyte differentiation GO:0002521 342 0.031
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
t cell differentiation GO:0030217 174 0.031
regulation of system process GO:0044057 200 0.030
cargo loading into vesicle GO:0035459 3 0.030
transmembrane transport GO:0055085 412 0.030
regulation of t cell activation GO:0050863 170 0.030
lymphocyte differentiation GO:0030098 242 0.030
response to endoplasmic reticulum stress GO:0034976 53 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
cellular lipid metabolic process GO:0044255 323 0.029
asymmetric neuroblast division GO:0055059 1 0.029
organelle localization GO:0051640 179 0.029
action potential GO:0001508 78 0.028
cellular metal ion homeostasis GO:0006875 151 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
protein localization to organelle GO:0033365 185 0.028
innate immune response GO:0045087 157 0.027
cellular protein catabolic process GO:0044257 155 0.027
protein modification by small protein conjugation GO:0032446 187 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
vacuole organization GO:0007033 38 0.026
oxidation reduction process GO:0055114 342 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
protein targeting GO:0006605 143 0.025
activation of adenylate cyclase activity GO:0007190 4 0.025
cellular ion homeostasis GO:0006873 165 0.025
glycoprotein metabolic process GO:0009100 116 0.025
regulation of actin nucleation GO:0051125 4 0.025
defense response to bacterium GO:0042742 119 0.024
positive regulation of leukocyte differentiation GO:1902107 86 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
sensory perception of umami taste GO:0050917 4 0.024
purine containing compound metabolic process GO:0072521 311 0.024
positive regulation of endocytosis GO:0045807 42 0.024
retrograde transport endosome to golgi GO:0042147 2 0.023
cell type specific apoptotic process GO:0097285 268 0.023
lipid localization GO:0010876 126 0.023
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
lateral inhibition GO:0046331 1 0.023
divalent inorganic cation transport GO:0072511 178 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
axon ensheathment GO:0008366 76 0.022
asymmetric stem cell division GO:0098722 3 0.022
positive regulation of protein modification process GO:0031401 299 0.022
regulation of cell motility GO:2000145 236 0.022
alpha beta t cell activation GO:0046631 91 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
photoreceptor cell differentiation GO:0046530 52 0.022
blood coagulation GO:0007596 76 0.021
regulation of cell activation GO:0050865 289 0.021
regulation of hydrolase activity GO:0051336 246 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
response to organic cyclic compound GO:0014070 198 0.021
positive regulation of cell development GO:0010720 237 0.021
regulation of organelle organization GO:0033043 289 0.020
wound healing GO:0042060 157 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
positive regulation of t cell activation GO:0050870 101 0.020
positive regulation of lymphocyte activation GO:0051251 140 0.020
regulation of transferase activity GO:0051338 263 0.020
sensory perception GO:0007600 245 0.020
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.020
vacuolar transport GO:0007034 11 0.020
protein localization to vacuole GO:0072665 4 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
regulation of body fluid levels GO:0050878 162 0.020
Human
receptor mediated endocytosis GO:0006898 51 0.020
organelle assembly GO:0070925 177 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
cellular ketone metabolic process GO:0042180 84 0.019
myosin filament assembly GO:0031034 2 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
cellular homeostasis GO:0019725 240 0.019
camera type eye development GO:0043010 266 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
striated muscle myosin thick filament assembly GO:0071688 1 0.019
cytoskeleton dependent intracellular transport GO:0030705 50 0.019
synapse organization GO:0050808 125 0.019
connective tissue development GO:0061448 179 0.019
wnt signaling pathway GO:0016055 188 0.019
gland development GO:0048732 330 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
alpha beta t cell differentiation GO:0046632 69 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
cellular response to lipid GO:0071396 145 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
response to acid chemical GO:0001101 111 0.018
macromolecule methylation GO:0043414 120 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
multicellular organism growth GO:0035264 161 0.017
extracellular matrix organization GO:0030198 147 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
cellular protein complex assembly GO:0043623 116 0.017
regulation of protein kinase activity GO:0045859 232 0.017
regulation of cell cycle GO:0051726 281 0.017
digestive system development GO:0055123 200 0.017
regulation of cell migration GO:0030334 219 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
regulation of actin cytoskeleton organization GO:0032956 84 0.017
mitotic cell cycle GO:0000278 195 0.016
ossification GO:0001503 216 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
regulation of alpha beta t cell activation GO:0046634 53 0.016
establishment of protein localization to vacuole GO:0072666 4 0.016
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
cytokinetic process GO:0032506 2 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
toxin transport GO:1901998 38 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of cell cycle process GO:0010564 160 0.016
transmission of nerve impulse GO:0019226 76 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
blood circulation GO:0008015 195 0.016
regulation of map kinase activity GO:0043405 120 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
extracellular structure organization GO:0043062 148 0.015
regulation of cell projection organization GO:0031344 206 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
molting cycle GO:0042303 90 0.015
sensory organ morphogenesis GO:0090596 242 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
epithelial cell development GO:0002064 159 0.015
regulation of membrane potential GO:0042391 192 0.015
neuron death GO:0070997 154 0.015
eye photoreceptor cell differentiation GO:0001754 41 0.015
ameboidal type cell migration GO:0001667 128 0.015
actomyosin structure organization GO:0031032 56 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
aromatic compound catabolic process GO:0019439 286 0.015
myosin filament organization GO:0031033 3 0.015
locomotory behavior GO:0007626 195 0.015
sulfur compound biosynthetic process GO:0044272 37 0.014
positive regulation of cell activation GO:0050867 158 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
muscle system process GO:0003012 141 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
organic hydroxy compound transport GO:0015850 93 0.014
pole plasm assembly GO:0007315 2 0.014
response to inorganic substance GO:0010035 96 0.014
neuronal action potential GO:0019228 54 0.014
regulation of exit from mitosis GO:0007096 1 0.014
regulation of intracellular transport GO:0032386 159 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
dendrite development GO:0016358 115 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of endocytosis GO:0030100 69 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
ear development GO:0043583 200 0.014
carbohydrate metabolic process GO:0005975 230 0.014
cellular response to extracellular stimulus GO:0031668 81 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
peptidyl amino acid modification GO:0018193 336 0.013
regulation of t cell differentiation GO:0045580 83 0.013
cartilage development GO:0051216 140 0.013
protein ubiquitination GO:0016567 171 0.013
regulation of ossification GO:0030278 112 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
regulation of secretion by cell GO:1903530 249 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
pharynx development GO:0060465 1 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
developmental maturation GO:0021700 193 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
regulation of osteoblast differentiation GO:0045667 67 0.013
regulation of neuron death GO:1901214 134 0.013
response to organonitrogen compound GO:0010243 246 0.013
cognition GO:0050890 149 0.013
nuclear transport GO:0051169 139 0.013
hemostasis GO:0007599 78 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
spermatid differentiation GO:0048515 115 0.013
positive regulation of organelle organization GO:0010638 128 0.013
arp2 3 complex mediated actin nucleation GO:0034314 3 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
embryonic skeletal system development GO:0048706 120 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of alpha beta t cell differentiation GO:0046637 35 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
mitotic cell cycle process GO:1903047 159 0.012
regulation of mapk cascade GO:0043408 248 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
neuron apoptotic process GO:0051402 142 0.012
methylation GO:0032259 134 0.012
muscle contraction GO:0006936 101 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
chromatin organization GO:0006325 206 0.012
gliogenesis GO:0042063 141 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
immune effector process GO:0002252 321 0.012
intracellular mrna localization GO:0008298 4 0.012
regionalization GO:0003002 337 0.012
protein oligomerization GO:0051259 67 0.012
regulation of defense response GO:0031347 233 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
digestive tract development GO:0048565 190 0.012
apoptotic signaling pathway GO:0097190 306 0.012
small molecule biosynthetic process GO:0044283 132 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
establishment of glial blood brain barrier GO:0060857 2 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
macromolecule glycosylation GO:0043413 55 0.012
purine ribonucleotide biosynthetic process GO:0009152 59 0.012
positive regulation of alpha beta t cell activation GO:0046635 39 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
muscle tissue development GO:0060537 308 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
nucleoside bisphosphate biosynthetic process GO:0033866 6 0.012
regulation of protein localization GO:0032880 231 0.012
divalent metal ion transport GO:0070838 172 0.012
protein maturation GO:0051604 176 0.012
synaptic transmission GO:0007268 329 0.012
coagulation GO:0050817 78 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of multi organism process GO:0043900 111 0.012
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
regulation of actin filament based process GO:0032970 99 0.011
positive regulation of transferase activity GO:0051347 167 0.011
cell division GO:0051301 120 0.011
Fly
positive regulation of cell substrate adhesion GO:0010811 47 0.011
response to ph GO:0009268 14 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
response to radiation GO:0009314 165 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
tissue homeostasis GO:0001894 115 0.011
microtubule based movement GO:0007018 84 0.011
retina development in camera type eye GO:0060041 119 0.011
skeletal system morphogenesis GO:0048705 203 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
substrate adhesion dependent cell spreading GO:0034446 30 0.011
sulfur compound metabolic process GO:0006790 100 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
glucose homeostasis GO:0042593 128 0.011
negative regulation of neuron death GO:1901215 98 0.011
regulation of hormone levels GO:0010817 211 0.011
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.011
positive regulation of glial cell proliferation GO:0060252 4 0.011
epithelial cell proliferation GO:0050673 174 0.011
striated muscle tissue development GO:0014706 293 0.011
mesodermal cell migration GO:0008078 4 0.011
negative regulation of protein modification process GO:0031400 163 0.011
regulation of cellular component size GO:0032535 121 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
fibrinolysis GO:0042730 3 0.011
neural tube development GO:0021915 160 0.011
glial cell differentiation GO:0010001 131 0.011
peptidyl serine modification GO:0018209 83 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
positive regulation of cell death GO:0010942 224 0.011
cell growth GO:0016049 130 0.011
regulation of cell division GO:0051302 76 0.011
sensory perception of light stimulus GO:0050953 54 0.011
nucleoside catabolic process GO:0009164 206 0.011
fibroblast migration GO:0010761 21 0.011
mapk cascade GO:0000165 281 0.011
forebrain development GO:0030900 302 0.011
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
cellular response to external stimulus GO:0071496 88 0.011
anion transport GO:0006820 177 0.011
cell substrate adhesion GO:0031589 130 0.011
circulatory system process GO:0003013 197 0.011
cellular calcium ion homeostasis GO:0006874 119 0.010
dna methylation GO:0006306 43 0.010
skeletal system development GO:0001501 356 0.010
mitotic cytokinesis GO:0000281 4 0.010
forebrain neuron differentiation GO:0021879 52 0.010
cell activation involved in immune response GO:0002263 126 0.010
body morphogenesis GO:0010171 45 0.010
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.010
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
cell fate commitment GO:0045165 210 0.010
cellular alcohol biosynthetic process GO:0044108 3 0.010
viral process GO:0016032 41 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
chromatin modification GO:0016568 187 0.010
regulation of protein catabolic process GO:0042176 108 0.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.010
purine containing compound biosynthetic process GO:0072522 70 0.010
nucleoside metabolic process GO:0009116 246 0.010
steroid metabolic process GO:0008202 119 0.010
microtubule based process GO:0007017 236 0.010
dna conformation change GO:0071103 37 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
cell adhesion GO:0007155 329 0.010
synaptic vesicle localization GO:0097479 59 0.010
positive regulation of wnt signaling pathway GO:0030177 45 0.010
regulation of metal ion transport GO:0010959 106 0.010
heart process GO:0003015 94 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
anatomical structure homeostasis GO:0060249 145 0.010

Copa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.023
disease of anatomical entity DOID:7 0 0.023
connective tissue disease DOID:65 0 0.023
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.022
bone disease DOID:0080001 0 0.013
bone development disease DOID:0080006 0 0.011
osteochondrodysplasia DOID:2256 0 0.011