Mus musculus

0 known processes

Cops4

COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)

(Aliases: D5Ertd774e,MGC151203,MGC151177,AW208976)

Cops4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 21 0.861
Human
oocyte anterior posterior axis specification GO:0007314 2 0.484
cytokinesis GO:0000910 17 0.356
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.325
cellular protein catabolic process GO:0044257 155 0.299
modification dependent macromolecule catabolic process GO:0043632 133 0.274
protein modification by small protein conjugation or removal GO:0070647 207 0.263
Human
modification dependent protein catabolic process GO:0019941 133 0.262
proteasomal protein catabolic process GO:0010498 98 0.262
regulation of cell cycle process GO:0010564 160 0.238
regulation of cellular protein catabolic process GO:1903362 61 0.196
cell division GO:0051301 120 0.184
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.184
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.175
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.174
regulation of proteasomal protein catabolic process GO:0061136 46 0.172
lateral inhibition GO:0046331 1 0.161
oocyte construction GO:0007308 2 0.159
regulation of cell cycle GO:0051726 281 0.155
ubiquitin dependent protein catabolic process GO:0006511 129 0.149
regulation of cellular catabolic process GO:0031329 242 0.148
oocyte axis specification GO:0007309 2 0.131
mitotic cell cycle process GO:1903047 159 0.121
dna integrity checkpoint GO:0031570 28 0.121
purine ribonucleotide metabolic process GO:0009150 290 0.120
regulation of cell cycle phase transition GO:1901987 77 0.113
regulation of protein catabolic process GO:0042176 108 0.108
ribonucleoside triphosphate metabolic process GO:0009199 220 0.108
macromolecule catabolic process GO:0009057 281 0.104
protein catabolic process GO:0030163 221 0.102
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.097
synaptic transmission GO:0007268 329 0.097
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.096
germ cell development GO:0007281 185 0.084
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.083
regulation of mitotic cell cycle GO:0007346 126 0.082
maternal determination of anterior posterior axis embryo GO:0008358 2 0.079
purine containing compound metabolic process GO:0072521 311 0.079
negative regulation of protein processing GO:0010955 79 0.077
cellular macromolecule catabolic process GO:0044265 206 0.077
nuclear division GO:0000280 158 0.077
negative regulation of protein metabolic process GO:0051248 282 0.076
negative regulation of mitotic cell cycle GO:0045930 58 0.071
positive regulation of proteolysis GO:0045862 85 0.069
positive regulation of cell cycle GO:0045787 92 0.067
regulation of protein maturation GO:1903317 96 0.067
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.067
purine nucleoside metabolic process GO:0042278 241 0.064
regulation of protein processing GO:0070613 96 0.064
negative regulation of cellular protein metabolic process GO:0032269 247 0.063
protein maturation GO:0051604 176 0.062
positive regulation of protein catabolic process GO:0045732 60 0.061
mitotic cell cycle GO:0000278 195 0.060
negative regulation of cell cycle phase transition GO:1901988 48 0.060
purine nucleotide metabolic process GO:0006163 302 0.059
positive regulation of cellular catabolic process GO:0031331 148 0.058
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.055
negative regulation of cell cycle GO:0045786 123 0.055
proteasome assembly GO:0043248 1 0.054
negative regulation of protein maturation GO:1903318 79 0.053
exosomal secretion GO:1990182 1 0.052
microtubule cytoskeleton organization GO:0000226 157 0.052
atp metabolic process GO:0046034 75 0.051
positive regulation of protein modification process GO:0031401 299 0.050
mitotic cell cycle checkpoint GO:0007093 31 0.048
regulation of protein stability GO:0031647 52 0.047
cellular response to dna damage stimulus GO:0006974 207 0.047
ribonucleoside metabolic process GO:0009119 245 0.047
purine ribonucleoside metabolic process GO:0046128 241 0.046
gonad development GO:0008406 141 0.045
nucleoside monophosphate metabolic process GO:0009123 85 0.045
organelle assembly GO:0070925 177 0.044
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.043
protein localization to nucleus GO:0034504 121 0.042
nucleotide metabolic process GO:0009117 332 0.042
regulation of proteolysis GO:0030162 164 0.042
cell cycle checkpoint GO:0000075 47 0.041
cell fate commitment GO:0045165 210 0.041
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.041
purine nucleotide catabolic process GO:0006195 211 0.040
negative regulation of protein catabolic process GO:0042177 36 0.040
terminal button organization GO:0072553 3 0.039
regulation of cell division GO:0051302 76 0.039
camera type eye development GO:0043010 266 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
negative regulation of cell cycle process GO:0010948 69 0.037
regulation of mitotic cell cycle phase transition GO:1901990 73 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
negative regulation of intracellular signal transduction GO:1902532 167 0.036
purine nucleoside catabolic process GO:0006152 205 0.036
gliogenesis GO:0042063 141 0.035
development of primary sexual characteristics GO:0045137 143 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
developmental maturation GO:0021700 193 0.034
male gamete generation GO:0048232 285 0.034
organelle fission GO:0048285 170 0.034
exocytosis GO:0006887 121 0.034
purine nucleoside triphosphate metabolic process GO:0009144 226 0.034
carbohydrate derivative catabolic process GO:1901136 231 0.034
mitotic cytokinesis GO:0000281 4 0.032
mapk cascade GO:0000165 281 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
blastocyst development GO:0001824 80 0.031
nucleotide catabolic process GO:0009166 217 0.030
ribonucleoside catabolic process GO:0042454 206 0.030
oocyte development GO:0048599 33 0.030
spindle assembly involved in mitosis GO:0090307 4 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
segmentation GO:0035282 93 0.029
mitotic g2 dna damage checkpoint GO:0007095 8 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
microtubule based process GO:0007017 236 0.029
regulation of jnk cascade GO:0046328 62 0.028
ribonucleoside monophosphate metabolic process GO:0009161 80 0.028
negative regulation of cellular protein catabolic process GO:1903363 22 0.028
regulation of organelle organization GO:0033043 289 0.028
protein processing GO:0016485 163 0.027
maintenance of location GO:0051235 89 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
positive regulation of cellular protein catabolic process GO:1903364 34 0.027
ribonucleotide metabolic process GO:0009259 291 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
epithelial cell proliferation GO:0050673 174 0.026
peptidyl amino acid modification GO:0018193 336 0.026
ribose phosphate metabolic process GO:0019693 291 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.025
regulation of establishment of protein localization GO:0070201 181 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
genitalia development GO:0048806 37 0.024
negative regulation of proteolysis GO:0045861 74 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
nucleoside metabolic process GO:0009116 246 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
purine nucleoside monophosphate catabolic process GO:0009128 58 0.023
oocyte differentiation GO:0009994 35 0.022
muscle tissue development GO:0060537 308 0.022
endocytosis GO:0006897 168 0.022
g2 dna damage checkpoint GO:0031572 8 0.022
negative regulation of cellular catabolic process GO:0031330 47 0.022
protein localization to organelle GO:0033365 185 0.021
cation transmembrane transport GO:0098655 266 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.020
protein stabilization GO:0050821 25 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
stem cell differentiation GO:0048863 268 0.020
protein deubiquitination GO:0016579 19 0.020
endomembrane system organization GO:0010256 147 0.020
oogenesis GO:0048477 56 0.019
aromatic compound catabolic process GO:0019439 286 0.019
regulation of multi organism process GO:0043900 111 0.019
organophosphate catabolic process GO:0046434 232 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
axonogenesis GO:0007409 274 0.019
binding of sperm to zona pellucida GO:0007339 34 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
striated muscle tissue development GO:0014706 293 0.019
spermatid development GO:0007286 108 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
regulation of cellular amine metabolic process GO:0033238 20 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
hematopoietic stem cell differentiation GO:0060218 8 0.016
stress activated mapk cascade GO:0051403 80 0.016
regulation of hydrolase activity GO:0051336 246 0.016
blastoderm segmentation GO:0007350 13 0.016
cellular ketone metabolic process GO:0042180 84 0.016
fertilization GO:0009566 127 0.016
heterocycle catabolic process GO:0046700 280 0.016
cellular amine metabolic process GO:0044106 44 0.015
dna damage checkpoint GO:0000077 26 0.015
cell maturation GO:0048469 127 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
atp catabolic process GO:0006200 55 0.015
regionalization GO:0003002 337 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
sperm egg recognition GO:0035036 37 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.015
divalent inorganic cation transport GO:0072511 178 0.015
trna aminoacylation for protein translation GO:0006418 1 0.015
leukocyte migration GO:0050900 124 0.014
gene silencing GO:0016458 38 0.014
regulation of intracellular transport GO:0032386 159 0.014
nuclear transport GO:0051169 139 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.013
protein import into nucleus GO:0006606 95 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.013
protein secretion GO:0009306 111 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
purine containing compound catabolic process GO:0072523 213 0.013
regulation of cellular response to stress GO:0080135 159 0.013
blood circulation GO:0008015 195 0.012
double strand break repair GO:0006302 48 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
negative regulation of molecular function GO:0044092 258 0.012
embryonic axis specification GO:0000578 30 0.012
positive regulation of protein complex assembly GO:0031334 45 0.012
protein ubiquitination GO:0016567 171 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
regulation of ion transport GO:0043269 215 0.012
mitotic nuclear division GO:0007067 48 0.012
amine metabolic process GO:0009308 45 0.012
regulation of receptor activity GO:0010469 41 0.012
pole plasm assembly GO:0007315 2 0.012
female gamete generation GO:0007292 74 0.012
nitrogen compound transport GO:0071705 271 0.012
regulation of transferase activity GO:0051338 263 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
intracellular protein transport GO:0006886 204 0.012
negative regulation of dna damage response signal transduction by p53 class mediator GO:0043518 5 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
spindle organization GO:0007051 28 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
negative regulation of epithelial cell proliferation GO:0050680 64 0.012
divalent metal ion transport GO:0070838 172 0.011
dephosphorylation GO:0016311 129 0.011
mechanosensory behavior GO:0007638 6 0.011
single fertilization GO:0007338 82 0.011
cell cell signaling involved in cell fate commitment GO:0045168 35 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
regulation of protein localization GO:0032880 231 0.011
interspecies interaction between organisms GO:0044419 83 0.011
regulation of protein localization to nucleus GO:1900180 60 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of mapk cascade GO:0043408 248 0.011
inflammatory response GO:0006954 244 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
cytoplasmic microtubule organization GO:0031122 14 0.011
rna splicing GO:0008380 54 0.011
cation transport GO:0006812 399 0.010
spermatogenesis GO:0007283 284 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
guanosine containing compound metabolic process GO:1901068 144 0.010
response to inorganic substance GO:0010035 96 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
gtp catabolic process GO:0006184 143 0.010
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.010

Cops4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.039
disease of anatomical entity DOID:7 0 0.039
eye disease DOID:5614 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015