Mus musculus

9 known processes

Cops5

COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)

(Aliases: Jab1,CSN5,Mov34,AI303502,Sgn5)

Cops5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 21 1.000
Human Worm Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.744
Fly
modification dependent protein catabolic process GO:0019941 133 0.709
Fly
modification dependent macromolecule catabolic process GO:0043632 133 0.693
Fly
protein modification by small protein conjugation or removal GO:0070647 207 0.660
Human Worm Fly
protein catabolic process GO:0030163 221 0.641
Fly
cellular protein catabolic process GO:0044257 155 0.543
Fly
cellular response to dna damage stimulus GO:0006974 207 0.531
Fly
proteasomal protein catabolic process GO:0010498 98 0.530
Fly
macromolecule catabolic process GO:0009057 281 0.470
Fly
ubiquitin dependent protein catabolic process GO:0006511 129 0.425
Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.240
Fly
lateral inhibition GO:0046331 1 0.230
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.211
cellular macromolecule catabolic process GO:0044265 206 0.186
Fly
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.154
nucleotide metabolic process GO:0009117 332 0.154
regulation of cell cycle GO:0051726 281 0.153
purine ribonucleotide metabolic process GO:0009150 290 0.150
negative regulation of protein metabolic process GO:0051248 282 0.136
Fly
positive regulation of protein catabolic process GO:0045732 60 0.123
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.118
regulation of cellular protein catabolic process GO:1903362 61 0.115
Fly
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.114
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.104
Fly
spermatid differentiation GO:0048515 115 0.103
purine nucleotide catabolic process GO:0006195 211 0.102
organelle assembly GO:0070925 177 0.097
positive regulation of cellular component biogenesis GO:0044089 94 0.091
male gamete generation GO:0048232 285 0.089
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.089
Fly
mitotic cell cycle GO:0000278 195 0.088
Fly
regulation of proteolysis GO:0030162 164 0.086
Fly
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.085
cellular nitrogen compound catabolic process GO:0044270 280 0.084
nucleotide catabolic process GO:0009166 217 0.082
aromatic compound catabolic process GO:0019439 286 0.079
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.077
Fly
positive regulation of protein modification process GO:0031401 299 0.077
spindle assembly involved in mitosis GO:0090307 4 0.072
carbohydrate derivative catabolic process GO:1901136 231 0.072
nucleobase containing small molecule metabolic process GO:0055086 352 0.071
ribonucleoside triphosphate metabolic process GO:0009199 220 0.067
protein maturation GO:0051604 176 0.067
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.066
organelle fission GO:0048285 170 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.061
proteasome assembly GO:0043248 1 0.061
regulation of mitotic cell cycle GO:0007346 126 0.061
Fly
regulation of cellular component biogenesis GO:0044087 181 0.059
guanosine containing compound metabolic process GO:1901068 144 0.059
chromatin modification GO:0016568 187 0.058
ribonucleoside metabolic process GO:0009119 245 0.058
regulation of cell cycle process GO:0010564 160 0.058
Fly
purine containing compound metabolic process GO:0072521 311 0.057
regulation of protein maturation GO:1903317 96 0.056
Fly
intracellular protein transport GO:0006886 204 0.056
mitotic cell cycle process GO:1903047 159 0.055
Fly
heterocycle catabolic process GO:0046700 280 0.053
purine nucleotide metabolic process GO:0006163 302 0.052
chromatin organization GO:0006325 206 0.051
histone modification GO:0016570 159 0.050
cell fate commitment GO:0045165 210 0.047
organophosphate catabolic process GO:0046434 232 0.047
regulation of protein processing GO:0070613 96 0.046
Fly
purine ribonucleoside catabolic process GO:0046130 205 0.046
negative regulation of cell cycle GO:0045786 123 0.045
Fly
spermatid development GO:0007286 108 0.045
positive regulation of hydrolase activity GO:0051345 148 0.044
ribonucleoside triphosphate catabolic process GO:0009203 199 0.043
regulation of protein catabolic process GO:0042176 108 0.043
Fly
nuclear division GO:0000280 158 0.043
ribose phosphate metabolic process GO:0019693 291 0.042
nucleoside metabolic process GO:0009116 246 0.042
regulation of chromosome organization GO:0033044 83 0.041
negative regulation of proteolysis GO:0045861 74 0.040
Fly
organonitrogen compound catabolic process GO:1901565 264 0.040
atp metabolic process GO:0046034 75 0.039
negative regulation of protein processing GO:0010955 79 0.039
Fly
purine nucleoside catabolic process GO:0006152 205 0.038
positive regulation of protein complex assembly GO:0031334 45 0.038
protein localization to organelle GO:0033365 185 0.038
microtubule cytoskeleton organization GO:0000226 157 0.038
covalent chromatin modification GO:0016569 163 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.037
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.037
cytoplasmic transport GO:0016482 234 0.036
protein targeting GO:0006605 143 0.036
ribonucleotide catabolic process GO:0009261 208 0.035
cell division GO:0051301 120 0.035
Worm
ribonucleoside monophosphate metabolic process GO:0009161 80 0.034
protein import GO:0017038 101 0.034
positive regulation of cellular protein catabolic process GO:1903364 34 0.034
Fly
mitotic cytokinesis GO:0000281 4 0.033
regulation of hydrolase activity GO:0051336 246 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
negative regulation of cell proliferation GO:0008285 296 0.033
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
protein stabilization GO:0050821 25 0.031
Fly
ribonucleotide metabolic process GO:0009259 291 0.031
dna recombination GO:0006310 92 0.031
protein processing GO:0016485 163 0.030
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.030
negative regulation of protein maturation GO:1903318 79 0.030
Fly
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.030
Fly
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.030
spermatogenesis GO:0007283 284 0.029
regulation of proteasomal protein catabolic process GO:0061136 46 0.029
Fly
positive regulation of kinase activity GO:0033674 155 0.029
purine containing compound catabolic process GO:0072523 213 0.029
regulation of cellular catabolic process GO:0031329 242 0.028
Fly
nuclear import GO:0051170 95 0.028
dna metabolic process GO:0006259 303 0.028
regulation of transferase activity GO:0051338 263 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
double strand break repair via homologous recombination GO:0000724 21 0.027
cellular protein complex assembly GO:0043623 116 0.027
double strand break repair GO:0006302 48 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
negative regulation of cell development GO:0010721 169 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of protein complex assembly GO:0043254 83 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
Fly
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.025
camera type eye development GO:0043010 266 0.025
protein acylation GO:0043543 64 0.025
er to golgi vesicle mediated transport GO:0006888 11 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
internal protein amino acid acetylation GO:0006475 42 0.024
amine metabolic process GO:0009308 45 0.024
microtubule based process GO:0007017 236 0.023
single fertilization GO:0007338 82 0.023
positive regulation of transferase activity GO:0051347 167 0.022
membrane organization GO:0061024 245 0.022
protein deubiquitination GO:0016579 19 0.022
Human
sperm individualization GO:0007291 1 0.022
peptidyl amino acid modification GO:0018193 336 0.022
neural tube formation GO:0001841 108 0.022
actin cytoskeleton organization GO:0030036 220 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
maintenance of location GO:0051235 89 0.022
developmental maturation GO:0021700 193 0.021
Fly
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.021
regulation of cytoplasmic transport GO:1903649 112 0.021
regulation of organelle organization GO:0033043 289 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
gonad development GO:0008406 141 0.020
Worm
recombinational repair GO:0000725 21 0.020
regulation of multi organism process GO:0043900 111 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.019
oocyte anterior posterior axis specification GO:0007314 2 0.019
Fly
negative regulation of immune system process GO:0002683 209 0.019
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
transmembrane transport GO:0055085 412 0.019
cytokinesis GO:0000910 17 0.019
Worm
regulation of cell cycle phase transition GO:1901987 77 0.019
Fly
gtp catabolic process GO:0006184 143 0.019
cell cell signaling involved in cell fate commitment GO:0045168 35 0.019
dna integrity checkpoint GO:0031570 28 0.018
Fly
germ cell development GO:0007281 185 0.018
Worm Fly
positive regulation of dna templated transcription elongation GO:0032786 2 0.018
regulation of histone modification GO:0031056 56 0.018
regulation of protein ubiquitination GO:0031396 52 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
organelle localization GO:0051640 179 0.018
regulation of intracellular transport GO:0032386 159 0.018
regulation of protein stability GO:0031647 52 0.018
Fly
cell cycle checkpoint GO:0000075 47 0.018
Fly
nucleoside monophosphate metabolic process GO:0009123 85 0.018
ossification GO:0001503 216 0.018
protein import into nucleus GO:0006606 95 0.018
negative regulation of protein catabolic process GO:0042177 36 0.018
Fly
development of primary sexual characteristics GO:0045137 143 0.017
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
golgi vesicle transport GO:0048193 30 0.017
regulation of ion transport GO:0043269 215 0.017
nucleoside catabolic process GO:0009164 206 0.017
regulation of mitotic cell cycle phase transition GO:1901990 73 0.017
Fly
protein localization to nucleus GO:0034504 121 0.017
leukocyte proliferation GO:0070661 172 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
negative regulation of cell cycle process GO:0010948 69 0.017
Fly
single organism nuclear import GO:1902593 95 0.017
regulation of establishment of protein localization GO:0070201 181 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
fertilization GO:0009566 127 0.016
regulation of peptidase activity GO:0052547 96 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
stem cell differentiation GO:0048863 268 0.016
striated muscle tissue development GO:0014706 293 0.016
regulation of kinase activity GO:0043549 249 0.016
protein neddylation GO:0045116 1 0.016
cellular amine metabolic process GO:0044106 44 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
Fly
regulation of protein localization to nucleus GO:1900180 60 0.015
negative regulation of cellular protein catabolic process GO:1903363 22 0.015
Fly
negative regulation of molecular function GO:0044092 258 0.015
spindle organization GO:0007051 28 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of protein localization GO:0032880 231 0.015
peptidyl lysine acetylation GO:0018394 45 0.015
histone acetylation GO:0016573 41 0.014
regulation of protein targeting GO:1903533 61 0.014
t cell proliferation GO:0042098 120 0.014
response to organonitrogen compound GO:0010243 246 0.014
stem cell development GO:0048864 219 0.014
regulation of protein kinase activity GO:0045859 232 0.014
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.014
positive regulation of proteolysis GO:0045862 85 0.014
Fly
organic hydroxy compound metabolic process GO:1901615 203 0.014
extracellular structure organization GO:0043062 148 0.014
intracellular mrna localization GO:0008298 4 0.014
positive regulation of cell death GO:0010942 224 0.013
positive regulation of organelle organization GO:0010638 128 0.013
positive regulation of peptidase activity GO:0010952 49 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.013
chromosome segregation GO:0007059 48 0.013
forebrain development GO:0030900 302 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of hormone levels GO:0010817 211 0.013
methylation GO:0032259 134 0.013
nuclear transport GO:0051169 139 0.013
regulation of cell growth GO:0001558 91 0.012
mitotic cell cycle checkpoint GO:0007093 31 0.012
Fly
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.012
protein polymerization GO:0051258 57 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of translation GO:0006417 71 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
Fly
cell maturation GO:0048469 127 0.012
Fly
peptidyl lysine modification GO:0018205 77 0.012
blood circulation GO:0008015 195 0.011
nitrogen compound transport GO:0071705 271 0.011
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
sensory organ morphogenesis GO:0090596 242 0.011
Fly
cellular amino acid metabolic process GO:0006520 103 0.011
dna repair GO:0006281 107 0.011
positive regulation of chromosome organization GO:2001252 33 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
Fly
circulatory system process GO:0003013 197 0.011
tube formation GO:0035148 140 0.011
apoptotic signaling pathway GO:0097190 306 0.011
ion transmembrane transport GO:0034220 361 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
mitotic g2 dna damage checkpoint GO:0007095 8 0.011
Fly
regulation of secretion GO:0051046 274 0.011
inflammatory response GO:0006954 244 0.011
epithelial cell proliferation GO:0050673 174 0.011
leukocyte migration GO:0050900 124 0.011
blastocyst development GO:0001824 80 0.011
regulation of system process GO:0044057 200 0.011
positive regulation of cell cycle GO:0045787 92 0.011
Fly
sperm egg recognition GO:0035036 37 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
digestive system development GO:0055123 200 0.010
rna splicing via endonucleolytic cleavage and ligation GO:0000394 1 0.010
muscle tissue development GO:0060537 308 0.010
locomotory behavior GO:0007626 195 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
response to organic cyclic compound GO:0014070 198 0.010

Cops5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.010