Mus musculus

0 known processes

Creld2

cysteine-rich with EGF-like domains 2

(Aliases: C85758,5730592L21Rik)

Creld2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to topologically incorrect protein GO:0035966 25 0.975
cellular response to topologically incorrect protein GO:0035967 25 0.962
er nucleus signaling pathway GO:0006984 27 0.738
endoplasmic reticulum unfolded protein response GO:0030968 19 0.717
response to unfolded protein GO:0006986 21 0.541
cellular macromolecule catabolic process GO:0044265 206 0.509
protein catabolic process GO:0030163 221 0.412
cellular response to interleukin 4 GO:0071353 21 0.401
glycoprotein biosynthetic process GO:0009101 89 0.395
protein targeting to er GO:0045047 2 0.331
carbohydrate derivative biosynthetic process GO:1901137 183 0.239
vascular process in circulatory system GO:0003018 62 0.236
peptidyl asparagine modification GO:0018196 1 0.214
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.191
response to yeast GO:0001878 6 0.169
glycoprotein metabolic process GO:0009100 116 0.161
protein glycosylation GO:0006486 55 0.140
muscle cell differentiation GO:0042692 261 0.114
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.103
macromolecule catabolic process GO:0009057 281 0.099
response to organonitrogen compound GO:0010243 246 0.094
fertilization GO:0009566 127 0.084
amine metabolic process GO:0009308 45 0.081
protein targeting to membrane GO:0006612 20 0.078
positive regulation of interleukin 6 secretion GO:2000778 1 0.077
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.076
cellular response to toxic substance GO:0097237 7 0.073
substantia nigra development GO:0021762 2 0.070
t cell differentiation GO:0030217 174 0.070
regulation of cellular amine metabolic process GO:0033238 20 0.070
peptidyl amino acid modification GO:0018193 336 0.068
chaperone mediated protein folding GO:0061077 10 0.067
modification dependent protein catabolic process GO:0019941 133 0.063
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.061
protein n linked glycosylation GO:0006487 12 0.057
body morphogenesis GO:0010171 45 0.057
protein localization to organelle GO:0033365 185 0.056
response to organophosphorus GO:0046683 22 0.055
cellular response to extracellular stimulus GO:0031668 81 0.055
protein n linked glycosylation via asparagine GO:0018279 1 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.051
response to antibiotic GO:0046677 11 0.050
cellular protein catabolic process GO:0044257 155 0.049
regulation of anatomical structure size GO:0090066 178 0.049
protein modification by small protein conjugation or removal GO:0070647 207 0.049
proteasomal protein catabolic process GO:0010498 98 0.049
posttranscriptional regulation of gene expression GO:0010608 155 0.048
cellular amine metabolic process GO:0044106 44 0.047
response to endoplasmic reticulum stress GO:0034976 53 0.047
regulation of tube size GO:0035150 57 0.046
regulation of mrna metabolic process GO:1903311 43 0.044
cellular response to organonitrogen compound GO:0071417 145 0.043
regulation of cell cycle GO:0051726 281 0.042
cellular response to external stimulus GO:0071496 88 0.042
nitrogen compound transport GO:0071705 271 0.042
t cell activation GO:0042110 289 0.041
dopaminergic neuron differentiation GO:0071542 14 0.041
regulation of systemic arterial blood pressure GO:0003073 61 0.040
leukocyte differentiation GO:0002521 342 0.039
poly a mrna export from nucleus GO:0016973 4 0.038
transmembrane transport GO:0055085 412 0.037
regulation of kinase activity GO:0043549 249 0.037
digestive tract morphogenesis GO:0048546 147 0.037
positive regulation of programmed cell death GO:0043068 218 0.037
nuclear division GO:0000280 158 0.036
cotranslational protein targeting to membrane GO:0006613 2 0.036
establishment of protein localization to membrane GO:0090150 54 0.035
regulation of rna splicing GO:0043484 37 0.035
cell recognition GO:0008037 83 0.034
muscle tissue development GO:0060537 308 0.034
sensory organ morphogenesis GO:0090596 242 0.034
lipid localization GO:0010876 126 0.034
maintenance of protein localization in organelle GO:0072595 2 0.034
glycosylation GO:0070085 62 0.033
male genitalia morphogenesis GO:0048808 4 0.033
pore complex assembly GO:0046931 3 0.033
establishment of protein localization to endoplasmic reticulum GO:0072599 2 0.033
protein folding GO:0006457 28 0.032
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.031
circulatory system process GO:0003013 197 0.031
cellular amino acid metabolic process GO:0006520 103 0.030
positive regulation of systemic arterial blood pressure GO:0003084 9 0.030
macromolecule glycosylation GO:0043413 55 0.029
response to testosterone GO:0033574 3 0.028
posttranslational protein targeting to membrane GO:0006620 2 0.028
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.028
positive regulation of blood pressure GO:0045777 21 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
regulation of organelle organization GO:0033043 289 0.028
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.028
positive regulation of cell adhesion GO:0045785 80 0.027
regulation of mrna processing GO:0050684 41 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
protein ubiquitination GO:0016567 171 0.026
positive regulation of cardiac muscle contraction GO:0060452 2 0.026
gland development GO:0048732 330 0.026
renal system development GO:0072001 225 0.026
response to growth factor GO:0070848 198 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
interleukin 6 production GO:0032635 58 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
midgut development GO:0007494 4 0.024
positive regulation of cell migration GO:0030335 109 0.024
cellular response to biotic stimulus GO:0071216 92 0.024
translation GO:0006412 93 0.024
protein transmembrane transport GO:0071806 8 0.023
positive regulation of cell motility GO:2000147 116 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
mrna splicing via spliceosome GO:0000398 43 0.022
lipid biosynthetic process GO:0008610 179 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
regulation of cytokine production GO:0001817 266 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
response to organic cyclic compound GO:0014070 198 0.022
positive regulation of transferase activity GO:0051347 167 0.022
regulation of translation GO:0006417 71 0.022
regulation of hydrolase activity GO:0051336 246 0.021
cellular ketone metabolic process GO:0042180 84 0.021
ear development GO:0043583 200 0.021
cation transmembrane transport GO:0098655 266 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
kidney development GO:0001822 213 0.021
regulation of phosphatase activity GO:0010921 12 0.021
positive regulation of growth hormone secretion GO:0060124 3 0.021
nuclear transport GO:0051169 139 0.021
positive regulation of cell activation GO:0050867 158 0.021
regulation of organ morphogenesis GO:2000027 144 0.020
purine containing compound catabolic process GO:0072523 213 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cellular response to glucose starvation GO:0042149 5 0.020
protein localization to nucleus GO:0034504 121 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.020
carbohydrate metabolic process GO:0005975 230 0.020
response to interleukin 4 GO:0070670 23 0.020
maintenance of location GO:0051235 89 0.020
cellular response to antibiotic GO:0071236 4 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.019
regulation of t cell activation GO:0050863 170 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
response to purine containing compound GO:0014074 28 0.019
lateral inhibition GO:0046331 1 0.019
mrna metabolic process GO:0016071 84 0.019
regulation of transferase activity GO:0051338 263 0.019
blood circulation GO:0008015 195 0.019
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.019
leukocyte migration GO:0050900 124 0.019
interleukin 6 secretion GO:0072604 3 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
striated muscle cell development GO:0055002 125 0.018
digestive system development GO:0055123 200 0.018
urogenital system development GO:0001655 261 0.018
cerebellum development GO:0021549 77 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.018
regulation of cell motility GO:2000145 236 0.018
protein targeting GO:0006605 143 0.018
organelle assembly GO:0070925 177 0.018
lymphocyte differentiation GO:0030098 242 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
regulation of lymphocyte activation GO:0051249 240 0.017
regulation of multi organism process GO:0043900 111 0.017
cerebellar cortex development GO:0021695 48 0.017
organelle fission GO:0048285 170 0.017
cellular chemical homeostasis GO:0055082 215 0.017
response to extracellular stimulus GO:0009991 127 0.017
cellular response to nutrient levels GO:0031669 64 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
gene silencing by mirna GO:0035195 10 0.017
positive regulation of protein modification process GO:0031401 299 0.016
photoreceptor cell differentiation GO:0046530 52 0.016
spindle assembly involved in mitosis GO:0090307 4 0.016
response to starvation GO:0042594 65 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.016
gpi anchor metabolic process GO:0006505 7 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
aromatic compound catabolic process GO:0019439 286 0.016
endodermal digestive tract morphogenesis GO:0061031 4 0.016
regulation of blood pressure GO:0008217 93 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
carbohydrate homeostasis GO:0033500 128 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
membrane organization GO:0061024 245 0.016
hindbrain development GO:0030902 128 0.016
spermatogenesis GO:0007283 284 0.016
regulation of cell migration GO:0030334 219 0.015
positive regulation of cell death GO:0010942 224 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
cytokine production GO:0001816 319 0.015
cation transport GO:0006812 399 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
response to nutrient levels GO:0031667 109 0.015
positive regulation of growth GO:0045927 104 0.015
response to oxygen levels GO:0070482 62 0.015
midbrain development GO:0030901 35 0.015
regulation of blood vessel size GO:0050880 56 0.015
positive regulation of endocytosis GO:0045807 42 0.015
actin cytoskeleton organization GO:0030036 220 0.015
positive regulation of t cell activation GO:0050870 101 0.015
interspecies interaction between organisms GO:0044419 83 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
regulation of establishment of protein localization GO:0070201 181 0.014
t cell differentiation in thymus GO:0033077 77 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
germ cell development GO:0007281 185 0.014
mitotic nuclear division GO:0007067 48 0.014
response to radiation GO:0009314 165 0.014
mitotic cell cycle GO:0000278 195 0.014
positive regulation of cytokine production GO:0001819 174 0.014
neural nucleus development GO:0048857 22 0.014
single fertilization GO:0007338 82 0.014
regulation of dendritic cell chemotaxis GO:2000508 1 0.014
toxin transport GO:1901998 38 0.014
mrna processing GO:0006397 63 0.014
endocytosis GO:0006897 168 0.014
meiotic nuclear division GO:0007126 115 0.014
negative regulation of cell development GO:0010721 169 0.014
anatomical structure arrangement GO:0048532 20 0.014
protein secretion GO:0009306 111 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.013
positive regulation of protein secretion GO:0050714 52 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
striated muscle tissue development GO:0014706 293 0.013
vasoconstriction GO:0042310 27 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
immunoglobulin production GO:0002377 73 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
immunoglobulin secretion GO:0048305 17 0.013
dephosphorylation GO:0016311 129 0.013
muscle fiber development GO:0048747 76 0.013
regulation of t cell differentiation GO:0045580 83 0.013
eye photoreceptor cell differentiation GO:0001754 41 0.013
organelle disassembly GO:1903008 2 0.013
connective tissue development GO:0061448 179 0.012
er overload response GO:0006983 6 0.012
sperm egg recognition GO:0035036 37 0.012
regulation of hormone levels GO:0010817 211 0.012
hormone secretion GO:0046879 128 0.012
meiotic cell cycle GO:0051321 122 0.012
glycerophospholipid biosynthetic process GO:0046474 32 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
muscle cell development GO:0055001 133 0.012
apoptotic signaling pathway GO:0097190 306 0.012
hindbrain morphogenesis GO:0021575 46 0.012
cell activation involved in immune response GO:0002263 126 0.012
positive regulation of secretion GO:0051047 130 0.011
hepaticobiliary system development GO:0061008 67 0.011
regulation of cellular response to stress GO:0080135 159 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
positive regulation of translation GO:0045727 19 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
b cell activation GO:0042113 161 0.011
skeletal system development GO:0001501 356 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
peptide transport GO:0015833 133 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
polyamine biosynthetic process GO:0006596 2 0.011
regulation of neuron differentiation GO:0045664 281 0.011
glucose homeostasis GO:0042593 128 0.011
cell adhesion GO:0007155 329 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
photoreceptor cell development GO:0042461 40 0.011
receptor mediated endocytosis GO:0006898 51 0.011
response to acid chemical GO:0001101 111 0.011
forebrain development GO:0030900 302 0.011
wnt signaling pathway GO:0016055 188 0.011
membrane lipid biosynthetic process GO:0046467 32 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
protein hydroxylation GO:0018126 4 0.010
chemotaxis GO:0006935 247 0.010
protein lipidation GO:0006497 28 0.010
rna processing GO:0006396 105 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
regulation of protein secretion GO:0050708 82 0.010
lipoprotein biosynthetic process GO:0042158 33 0.010
regulation of intracellular transport GO:0032386 159 0.010
pharynx development GO:0060465 1 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
regulation of metal ion transport GO:0010959 106 0.010
cell type specific apoptotic process GO:0097285 268 0.010
digestive tract development GO:0048565 190 0.010
male sex differentiation GO:0046661 109 0.010
insulin secretion GO:0030073 89 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
nucleotide catabolic process GO:0009166 217 0.010
rna modification GO:0009451 20 0.010

Creld2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system cancer DOID:0060083 0 0.118
cancer DOID:162 0 0.118
disease of cellular proliferation DOID:14566 0 0.118
organ system cancer DOID:0050686 0 0.118
bone development disease DOID:0080006 0 0.024
bone disease DOID:0080001 0 0.024
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
connective tissue disease DOID:65 0 0.024
myopathy DOID:423 0 0.022
muscular disease DOID:0080000 0 0.022
muscular dystrophy DOID:9884 0 0.022
limb girdle muscular dystrophy DOID:11724 0 0.022
muscle tissue disease DOID:66 0 0.022