Mus musculus

27 known processes

Crkl

v-crk sarcoma virus CT10 oncogene homolog (avian)-like

(Aliases: 1110025F07Rik,AA589403,Crkol,AI325100)

Crkl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of clathrin mediated endocytosis GO:2000369 4 0.722
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.690
regulation of cellular ketone metabolic process GO:0010565 66 0.669
regulation of cellular amino acid metabolic process GO:0006521 5 0.548
regulation of cellular amine metabolic process GO:0033238 20 0.533
cellular amino acid metabolic process GO:0006520 103 0.515
amine metabolic process GO:0009308 45 0.504
myeloid cell differentiation GO:0030099 233 0.427
regulation of hydrolase activity GO:0051336 246 0.405
positive regulation of nervous system development GO:0051962 221 0.401
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.396
leukocyte proliferation GO:0070661 172 0.386
mapk cascade GO:0000165 281 0.365
Fly
cell adhesion GO:0007155 329 0.362
single organism cell adhesion GO:0098602 156 0.325
cellular ketone metabolic process GO:0042180 84 0.322
synaptic transmission GO:0007268 329 0.321
regulation of protein kinase activity GO:0045859 232 0.317
regulation of lymphocyte activation GO:0051249 240 0.310
protein processing GO:0016485 163 0.284
positive regulation of protein phosphorylation GO:0001934 242 0.279
positive regulation of dna templated transcription elongation GO:0032786 2 0.275
leukocyte differentiation GO:0002521 342 0.274
regulation of cell activation GO:0050865 289 0.272
cellular amine metabolic process GO:0044106 44 0.270
t cell activation GO:0042110 289 0.267
canonical wnt signaling pathway GO:0060070 130 0.264
regulation of proteolysis GO:0030162 164 0.259
endocytosis GO:0006897 168 0.259
Worm Fly
rho protein signal transduction GO:0007266 32 0.256
ras protein signal transduction GO:0007265 77 0.256
regulation of kinase activity GO:0043549 249 0.253
lymphocyte proliferation GO:0046651 164 0.247
regionalization GO:0003002 337 0.241
regulation of protein tyrosine kinase activity GO:0061097 17 0.241
clathrin coat assembly GO:0048268 2 0.231
cellular lipid metabolic process GO:0044255 323 0.230
positive regulation of protein modification process GO:0031401 299 0.225
regulation of protein serine threonine kinase activity GO:0071900 157 0.215
positive regulation of programmed cell death GO:0043068 218 0.214
forebrain development GO:0030900 302 0.209
negative regulation of molecular function GO:0044092 258 0.204
negative regulation of cellular protein metabolic process GO:0032269 247 0.201
macromolecule catabolic process GO:0009057 281 0.194
dna metabolic process GO:0006259 303 0.193
regulation of transferase activity GO:0051338 263 0.190
response to molecule of bacterial origin GO:0002237 143 0.185
t cell proliferation GO:0042098 120 0.185
regulation of t cell activation GO:0050863 170 0.184
negative regulation of cell proliferation GO:0008285 296 0.183
regulation of vesicle mediated transport GO:0060627 139 0.181
wnt signaling pathway GO:0016055 188 0.180
response to growth factor GO:0070848 198 0.180
regulation of cellular response to stress GO:0080135 159 0.177
Fly
negative regulation of cellular amine metabolic process GO:0033239 1 0.177
immune effector process GO:0002252 321 0.176
positive regulation of cellular amine metabolic process GO:0033240 5 0.163
lipid biosynthetic process GO:0008610 179 0.163
regulation of map kinase activity GO:0043405 120 0.162
cell substrate adhesion GO:0031589 130 0.161
negative regulation of phosphorylation GO:0042326 166 0.159
regulation of ras protein signal transduction GO:0046578 114 0.156
small gtpase mediated signal transduction GO:0007264 97 0.154
leukocyte activation involved in immune response GO:0002366 126 0.153
layer formation in cerebral cortex GO:0021819 13 0.153
regulation of cellular component biogenesis GO:0044087 181 0.150
positive regulation of apoptotic process GO:0043065 217 0.148
positive regulation of creb transcription factor activity GO:0032793 4 0.147
regulation of cell projection organization GO:0031344 206 0.146
organophosphate catabolic process GO:0046434 232 0.146
regulation of canonical wnt signaling pathway GO:0060828 82 0.145
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.145
pallium development GO:0021543 120 0.145
nucleoside triphosphate metabolic process GO:0009141 230 0.145
cytokine production GO:0001816 319 0.145
epidermal growth factor receptor signaling pathway GO:0007173 28 0.143
regulation of rho protein signal transduction GO:0035023 71 0.142
apoptotic signaling pathway GO:0097190 306 0.140
regulation of neuron differentiation GO:0045664 281 0.140
negative regulation of ras protein signal transduction GO:0046580 18 0.139
cellularization GO:0007349 1 0.138
t cell differentiation GO:0030217 174 0.137
phospholipid metabolic process GO:0006644 87 0.136
protein maturation GO:0051604 176 0.135
regulation of leukocyte proliferation GO:0070663 121 0.133
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.133
regulation of defense response GO:0031347 233 0.133
cation homeostasis GO:0055080 212 0.133
positive regulation of cell development GO:0010720 237 0.133
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.133
divalent inorganic cation homeostasis GO:0072507 138 0.132
cerebral cortex cell migration GO:0021795 44 0.128
negative regulation of phosphate metabolic process GO:0045936 184 0.126
peptidyl amino acid modification GO:0018193 336 0.125
protein modification by small protein conjugation GO:0032446 187 0.125
negative regulation of phosphorus metabolic process GO:0010563 184 0.125
positive regulation of stress activated mapk cascade GO:0032874 48 0.124
Fly
positive regulation of cytokine production GO:0001819 174 0.124
positive regulation of transferase activity GO:0051347 167 0.123
positive regulation of cell cycle GO:0045787 92 0.123
regulation of cell migration GO:0030334 219 0.122
leukocyte mediated immunity GO:0002443 174 0.121
cellular response to lipid GO:0071396 145 0.121
cytoplasmic transport GO:0016482 234 0.119
anatomical structure homeostasis GO:0060249 145 0.118
developmental maturation GO:0021700 193 0.116
peptidyl tyrosine phosphorylation GO:0018108 143 0.115
response to lipopolysaccharide GO:0032496 128 0.114
regulation of cell cycle GO:0051726 281 0.114
skeletal system development GO:0001501 356 0.113
positive regulation of jnk cascade GO:0046330 46 0.113
Fly
cellular response to cytokine stimulus GO:0071345 189 0.113
regulation of cytokine production GO:0001817 266 0.112
myeloid leukocyte differentiation GO:0002573 119 0.111
protein secretion GO:0009306 111 0.111
glutamate receptor signaling pathway GO:0007215 35 0.110
axonogenesis GO:0007409 274 0.110
regulation of apoptotic signaling pathway GO:2001233 197 0.110
erbb signaling pathway GO:0038127 32 0.110
regulation of cellular catabolic process GO:0031329 242 0.108
radial glia guided migration of purkinje cell GO:0021942 6 0.108
actin cytoskeleton organization GO:0030036 220 0.107
Mouse Worm
cell activation involved in immune response GO:0002263 126 0.106
morphogenesis of a branching structure GO:0001763 203 0.106
protein localization to organelle GO:0033365 185 0.105
positive regulation of neuron differentiation GO:0045666 141 0.105
regulation of mapk cascade GO:0043408 248 0.105
Fly
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.105
negative regulation of intracellular signal transduction GO:1902532 167 0.104
negative regulation of hydrolase activity GO:0051346 71 0.104
metal ion homeostasis GO:0055065 189 0.102
hematopoietic progenitor cell differentiation GO:0002244 143 0.102
extrinsic apoptotic signaling pathway GO:0097191 126 0.101
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.101
guanosine containing compound metabolic process GO:1901068 144 0.100
positive regulation of kinase activity GO:0033674 155 0.099
blood vessel morphogenesis GO:0048514 285 0.099
adaptive immune response GO:0002250 155 0.098
sensory perception GO:0007600 245 0.098
spermatogenesis GO:0007283 284 0.097
mitotic cell cycle GO:0000278 195 0.097
regulation of ion transport GO:0043269 215 0.097
cellular response to dna damage stimulus GO:0006974 207 0.097
germ cell development GO:0007281 185 0.096
Fly
negative regulation of protein metabolic process GO:0051248 282 0.096
regulation of receptor activity GO:0010469 41 0.096
organonitrogen compound catabolic process GO:1901565 264 0.095
negative regulation of immune system process GO:0002683 209 0.095
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.094
cerebral cortex radially oriented cell migration GO:0021799 31 0.094
stress activated mapk cascade GO:0051403 80 0.094
Fly
alpha beta t cell activation GO:0046631 91 0.093
regulation of epidermal growth factor receptor signaling pathway GO:0042058 13 0.093
activation of jun kinase activity GO:0007257 15 0.093
response to organonitrogen compound GO:0010243 246 0.092
regulation of innate immune response GO:0045088 91 0.091
regulation of protein maturation GO:1903317 96 0.091
purine nucleotide catabolic process GO:0006195 211 0.090
cellular response to organonitrogen compound GO:0071417 145 0.089
cerebral cortex development GO:0021987 86 0.089
protein localization to nucleus GO:0034504 121 0.088
activation of immune response GO:0002253 138 0.087
telencephalon cell migration GO:0022029 55 0.087
substrate adhesion dependent cell spreading GO:0034446 30 0.087
cellular response to hormone stimulus GO:0032870 150 0.087
male gamete generation GO:0048232 285 0.086
cell aging GO:0007569 35 0.085
regulation of leukocyte differentiation GO:1902105 159 0.084
lymphocyte differentiation GO:0030098 242 0.084
regulation of membrane potential GO:0042391 192 0.084
angiogenesis GO:0001525 201 0.083
regulation of establishment of protein localization GO:0070201 181 0.083
phagocytosis GO:0006909 66 0.082
Worm Fly
positive regulation of proteolysis GO:0045862 85 0.082
guanosine containing compound catabolic process GO:1901069 144 0.082
regulation of t cell proliferation GO:0042129 92 0.082
regulation of purine nucleotide metabolic process GO:1900542 169 0.082
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.081
protein import GO:0017038 101 0.081
positive regulation of jun kinase activity GO:0043507 30 0.081
positive regulation of dendritic spine morphogenesis GO:0061003 8 0.081
telencephalon development GO:0021537 186 0.080
body morphogenesis GO:0010171 45 0.080
positive regulation of defense response GO:0031349 124 0.080
alcohol metabolic process GO:0006066 116 0.080
synapse organization GO:0050808 125 0.080
response to oxidative stress GO:0006979 123 0.080
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.079
positive regulation of map kinase activity GO:0043406 84 0.078
regulation of organelle organization GO:0033043 289 0.078
Mouse
immune response regulating signaling pathway GO:0002764 125 0.078
forebrain cell migration GO:0021885 58 0.078
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 6 0.077
positive regulation of cell motility GO:2000147 116 0.077
regulation of ras gtpase activity GO:0032318 88 0.077
epithelial tube morphogenesis GO:0060562 303 0.077
glycerolipid metabolic process GO:0046486 122 0.076
positive regulation of neuron projection development GO:0010976 79 0.076
multicellular organismal homeostasis GO:0048871 164 0.076
regulation of protein processing GO:0070613 96 0.076
regulation of synaptic plasticity GO:0048167 87 0.075
actin filament organization GO:0007015 113 0.075
negative regulation of proteolysis GO:0045861 74 0.075
response to peptide GO:1901652 136 0.075
neuron projection guidance GO:0097485 141 0.074
cytokine mediated signaling pathway GO:0019221 115 0.073
regulation of peptidase activity GO:0052547 96 0.073
regulation of neuron projection development GO:0010975 169 0.073
positive regulation of leukocyte mediated immunity GO:0002705 70 0.073
positive regulation of cell migration GO:0030335 109 0.072
positive regulation of rac gtpase activity GO:0032855 14 0.072
positive regulation of mapk cascade GO:0043410 170 0.072
Fly
embryonic placenta development GO:0001892 98 0.072
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.071
single organismal cell cell adhesion GO:0016337 131 0.071
lymphocyte mediated immunity GO:0002449 139 0.071
transmembrane transport GO:0055085 412 0.069
regulation of leukocyte mediated immunity GO:0002703 104 0.069
branching morphogenesis of an epithelial tube GO:0048754 159 0.069
positive regulation of protein kinase activity GO:0045860 144 0.068
peptidyl tyrosine modification GO:0018212 145 0.068
regulation of gtp catabolic process GO:0033124 113 0.067
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.067
protein ubiquitination GO:0016567 171 0.067
cellular nitrogen compound catabolic process GO:0044270 280 0.067
gland development GO:0048732 330 0.067
cellular response to growth factor stimulus GO:0071363 197 0.067
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.066
regulation of secretion by cell GO:1903530 249 0.066
morphogenesis of embryonic epithelium GO:0016331 159 0.066
cellular response to biotic stimulus GO:0071216 92 0.066
regulation of nucleotide catabolic process GO:0030811 122 0.066
homeostasis of number of cells GO:0048872 210 0.066
glycerolipid biosynthetic process GO:0045017 50 0.065
positive regulation of hydrolase activity GO:0051345 148 0.065
neuron migration GO:0001764 122 0.065
regulation of jnk cascade GO:0046328 62 0.065
Fly
negative regulation of kinase activity GO:0033673 81 0.064
intracellular protein transport GO:0006886 204 0.064
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.064
camera type eye development GO:0043010 266 0.064
placenta development GO:0001890 140 0.064
nucleoside phosphate catabolic process GO:1901292 222 0.064
axon guidance GO:0007411 141 0.064
response to acid chemical GO:0001101 111 0.064
regulation of reactive oxygen species metabolic process GO:2000377 40 0.064
positive regulation of t cell anergy GO:0002669 4 0.064
protein modification by small protein conjugation or removal GO:0070647 207 0.063
regulation of jun kinase activity GO:0043506 40 0.063
neural tube formation GO:0001841 108 0.063
organelle localization GO:0051640 179 0.063
g1 s transition of mitotic cell cycle GO:0000082 57 0.063
cellular ion homeostasis GO:0006873 165 0.063
photoreceptor cell differentiation GO:0046530 52 0.063
stem cell differentiation GO:0048863 268 0.063
regulation of stress activated mapk cascade GO:0032872 69 0.062
Fly
neural tube closure GO:0001843 90 0.062
erk1 and erk2 cascade GO:0070371 77 0.062
glycerophospholipid metabolic process GO:0006650 71 0.062
organic hydroxy compound metabolic process GO:1901615 203 0.062
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.061
regulation of rho gtpase activity GO:0032319 58 0.061
response to organic cyclic compound GO:0014070 198 0.061
protein catabolic process GO:0030163 221 0.061
t cell anergy GO:0002870 4 0.061
purine ribonucleotide catabolic process GO:0009154 208 0.061
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.061
cellular protein catabolic process GO:0044257 155 0.061
establishment of protein localization to organelle GO:0072594 118 0.060
regulation of glutamate receptor signaling pathway GO:1900449 16 0.060
sterol metabolic process GO:0016125 58 0.060
cellular homeostasis GO:0019725 240 0.060
regulation of transmembrane transport GO:0034762 128 0.059
gastrulation GO:0007369 116 0.059
mitotic cell cycle process GO:1903047 159 0.059
cellular protein complex assembly GO:0043623 116 0.059
regulation of purine nucleotide catabolic process GO:0033121 122 0.058
cation transport GO:0006812 399 0.057
stress activated protein kinase signaling cascade GO:0031098 81 0.057
Fly
sequestering of metal ion GO:0051238 19 0.056
lymphocyte homeostasis GO:0002260 64 0.056
regulation of body fluid levels GO:0050878 162 0.056
regulation of endocytosis GO:0030100 69 0.056
nucleoside phosphate metabolic process GO:0006753 338 0.056
positive regulation of cell activation GO:0050867 158 0.056
myeloid leukocyte activation GO:0002274 83 0.056
immune response activating signal transduction GO:0002757 116 0.056
regulation of endopeptidase activity GO:0052548 89 0.056
positive regulation of cell death GO:0010942 224 0.055
embryonic organ morphogenesis GO:0048562 276 0.055
negative regulation of apoptotic signaling pathway GO:2001234 104 0.055
negative regulation of wnt signaling pathway GO:0030178 73 0.055
cell fate commitment GO:0045165 210 0.055
immunoglobulin mediated immune response GO:0016064 69 0.054
regulation of protein transport GO:0051223 163 0.054
multicellular organism growth GO:0035264 161 0.054
phosphatidylinositol metabolic process GO:0046488 45 0.054
regulation of ion transmembrane transporter activity GO:0032412 54 0.054
cell cycle g1 s phase transition GO:0044843 57 0.053
regulation of hormone levels GO:0010817 211 0.053
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.053
neural tube development GO:0021915 160 0.053
steroid metabolic process GO:0008202 119 0.053
triglyceride biosynthetic process GO:0019432 17 0.053
regulation of stem cell differentiation GO:2000736 50 0.053
regulation of epithelial cell proliferation GO:0050678 141 0.053
modification dependent macromolecule catabolic process GO:0043632 133 0.053
negative regulation of protein modification process GO:0031400 163 0.052
regulation of integrin mediated signaling pathway GO:2001044 8 0.052
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.052
muscle tissue development GO:0060537 308 0.052
membrane organization GO:0061024 245 0.051
Worm Fly
regulation of lymphocyte proliferation GO:0050670 117 0.051
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.051
positive regulation of cell projection organization GO:0031346 95 0.051
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.051
sensory organ morphogenesis GO:0090596 242 0.050
cellular component assembly involved in morphogenesis GO:0010927 139 0.050
divalent inorganic cation transport GO:0072511 178 0.050
innate immune response GO:0045087 157 0.050
endodermal cell fate specification GO:0001714 4 0.050
negative regulation of neuron apoptotic process GO:0043524 92 0.050
stem cell development GO:0048864 219 0.049
purine ribonucleoside metabolic process GO:0046128 241 0.049
negative regulation of erbb signaling pathway GO:1901185 7 0.049
endomembrane system organization GO:0010256 147 0.049
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.049
digestive system development GO:0055123 200 0.049
positive regulation of clathrin mediated endocytosis GO:2000370 1 0.049
gtp catabolic process GO:0006184 143 0.049
endocrine system development GO:0035270 98 0.049
calcium ion homeostasis GO:0055074 127 0.049
glycosyl compound metabolic process GO:1901657 246 0.049
muscle cell differentiation GO:0042692 261 0.048
Zebrafish
wound healing GO:0042060 157 0.048
ribose phosphate metabolic process GO:0019693 291 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
lymphocyte anergy GO:0002249 4 0.048
negative regulation of cell cycle GO:0045786 123 0.048
ion transmembrane transport GO:0034220 361 0.048
cellular response to lipopolysaccharide GO:0071222 77 0.047
regulation of transporter activity GO:0032409 57 0.047
negative regulation of hormone metabolic process GO:0032351 4 0.047
regulation of cell adhesion GO:0030155 154 0.047
positive regulation of secretion GO:0051047 130 0.047
regulation of nucleoside metabolic process GO:0009118 130 0.047
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.047
cellular response to oxidative stress GO:0034599 76 0.047
myeloid cell homeostasis GO:0002262 114 0.047
nucleotide metabolic process GO:0009117 332 0.047
regulation of lymphocyte anergy GO:0002911 4 0.046
reactive oxygen species metabolic process GO:0072593 84 0.046
ribonucleoside triphosphate metabolic process GO:0009199 220 0.046
negative regulation of cell activation GO:0050866 111 0.046
lymphocyte activation involved in immune response GO:0002285 93 0.046
toll like receptor signaling pathway GO:0002224 38 0.046
positive regulation of secretion by cell GO:1903532 114 0.046
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.045
regulation of epidermal growth factor activated receptor activity GO:0007176 7 0.045
metencephalon development GO:0022037 89 0.045
spinal cord development GO:0021510 81 0.045
activation of rac gtpase activity GO:0032863 2 0.045
golgi localization GO:0051645 4 0.045
response to peptide hormone GO:0043434 127 0.045
vesicle organization GO:0016050 60 0.044
negative regulation of hormone biosynthetic process GO:0032353 4 0.044
aromatic compound catabolic process GO:0019439 286 0.044
ribonucleoside catabolic process GO:0042454 206 0.044
inositol lipid mediated signaling GO:0048017 41 0.044
purine nucleoside catabolic process GO:0006152 205 0.043
carbohydrate metabolic process GO:0005975 230 0.043
response to drug GO:0042493 75 0.043
skeletal muscle organ development GO:0060538 163 0.043
morphogenesis of a branching epithelium GO:0061138 193 0.043
response to fibroblast growth factor GO:0071774 47 0.043
regulation of protein binding GO:0043393 60 0.043
phosphatidylinositol mediated signaling GO:0048015 41 0.043
regulation of protein localization GO:0032880 231 0.043
engulfment of apoptotic cell GO:0043652 3 0.043
Worm
negative regulation of transferase activity GO:0051348 85 0.042
cellular response to molecule of bacterial origin GO:0071219 83 0.042
nitrogen compound transport GO:0071705 271 0.042
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.042
t cell receptor signaling pathway GO:0050852 46 0.042
vesicle coating GO:0006901 2 0.042
regulation of t cell anergy GO:0002667 4 0.042
acylglycerol metabolic process GO:0006639 55 0.042
positive regulation of mitotic cell cycle GO:0045931 41 0.041
organelle assembly GO:0070925 177 0.041
regulation of wnt signaling pathway GO:0030111 123 0.041
positive regulation of rho gtpase activity GO:0032321 41 0.041
heart morphogenesis GO:0003007 178 0.041
antigen receptor mediated signaling pathway GO:0050851 64 0.041
regulation of phospholipid catabolic process GO:0060696 2 0.041
b cell homeostasis GO:0001782 34 0.041
primary neural tube formation GO:0014020 95 0.040
heterocycle catabolic process GO:0046700 280 0.040
rac protein signal transduction GO:0016601 13 0.040
regulation of erbb signaling pathway GO:1901184 16 0.040
cell type specific apoptotic process GO:0097285 268 0.040
regulation of protein complex assembly GO:0043254 83 0.040
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.039
organic cyclic compound catabolic process GO:1901361 295 0.039
dna recombination GO:0006310 92 0.039
sterol transmembrane transport GO:0035382 2 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.039
nuclear transport GO:0051169 139 0.039
endoderm development GO:0007492 45 0.039
nucleoside catabolic process GO:0009164 206 0.039
epithelial cell proliferation GO:0050673 174 0.039
positive regulation of lymphocyte activation GO:0051251 140 0.039
negative regulation of nervous system development GO:0051961 156 0.038
negative regulation of protein maturation GO:1903318 79 0.038
skeletal system morphogenesis GO:0048705 203 0.038
regulation of muscle tissue development GO:1901861 97 0.038
regulation of lipid metabolic process GO:0019216 118 0.038
labyrinthine layer development GO:0060711 49 0.038
regulation of cellular component size GO:0032535 121 0.037
regulation of system process GO:0044057 200 0.037
regulation of protein secretion GO:0050708 82 0.037
regulation of t cell differentiation GO:0045580 83 0.037
macrophage activation GO:0042116 27 0.037
hormone metabolic process GO:0042445 86 0.037
epithelial tube formation GO:0072175 130 0.037
release of sequestered calcium ion into cytosol GO:0051209 42 0.037
regulation of cell cycle process GO:0010564 160 0.036
chemotaxis GO:0006935 247 0.036
regulation of secretion GO:0051046 274 0.036
regulation of erk1 and erk2 cascade GO:0070372 71 0.036
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.036
ameboidal type cell migration GO:0001667 128 0.036
Fly
positive regulation of adaptive immune response GO:0002821 61 0.036
neuron death GO:0070997 154 0.036
positive regulation of cell cycle process GO:0090068 61 0.036
regulation of adaptive immune response GO:0002819 90 0.036
midgut development GO:0007494 4 0.036
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.036
positive regulation of immune effector process GO:0002699 107 0.036
protein kinase b signaling GO:0043491 74 0.035
protein targeting GO:0006605 143 0.035
mitochondrion organization GO:0007005 134 0.035
regulation of intracellular transport GO:0032386 159 0.035
response to radiation GO:0009314 165 0.035
regulation of lymphocyte differentiation GO:0045619 107 0.035
rhythmic process GO:0048511 174 0.035
maintenance of location GO:0051235 89 0.035
activation of mapk activity GO:0000187 59 0.035
positive regulation of cell adhesion GO:0045785 80 0.035
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.035
regulation of nucleotide metabolic process GO:0006140 169 0.035
blood circulation GO:0008015 195 0.035
b cell differentiation GO:0030183 78 0.035
negative regulation of mapk cascade GO:0043409 65 0.035
posttranscriptional regulation of gene expression GO:0010608 155 0.035
negative regulation of protein processing GO:0010955 79 0.034
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
positive regulation of integrin mediated signaling pathway GO:2001046 5 0.034
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.034
neuromuscular process GO:0050905 99 0.034
regulation of cysteine type endopeptidase activity GO:2000116 65 0.034
positive regulation of nucleotide catabolic process GO:0030813 88 0.034
lipid phosphorylation GO:0046834 25 0.034
cellular calcium ion homeostasis GO:0006874 119 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.033
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
jak stat cascade GO:0007259 42 0.033
regulation of cell cycle phase transition GO:1901987 77 0.033
digestive tract development GO:0048565 190 0.033
histone methylation GO:0016571 71 0.033
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.033
regulation of neuron death GO:1901214 134 0.033
positive regulation of tor signaling GO:0032008 3 0.033
transmission of nerve impulse GO:0019226 76 0.033
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.033
hindbrain development GO:0030902 128 0.032
regulation of binding GO:0051098 111 0.032
b cell proliferation GO:0042100 53 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
cellular chemical homeostasis GO:0055082 215 0.032
ossification GO:0001503 216 0.032
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.032
action potential GO:0001508 78 0.032
regulation of ion transmembrane transport GO:0034765 119 0.032
epithelial cell development GO:0002064 159 0.032
Fly
regulation of inflammatory response GO:0050727 147 0.032
dna repair GO:0006281 107 0.032
neuron apoptotic process GO:0051402 142 0.031
peptidyl serine modification GO:0018209 83 0.031
chromatin organization GO:0006325 206 0.031
cellular response to organic cyclic compound GO:0071407 87 0.031
regulation of myeloid leukocyte differentiation GO:0002761 58 0.031
sequestering of calcium ion GO:0051208 18 0.031

Crkl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034