Mus musculus

179 known processes

Csf1r

colony stimulating factor 1 receptor

(Aliases: AI323359,Csfmr,CD115,M-CSFR,Fms,Fim-2,CSF-1R)

Csf1r biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.991
Mouse
regulation of cell activation GO:0050865 289 0.924
Mouse
cell adhesion GO:0007155 329 0.875
Mouse
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.865
negative regulation of immune system process GO:0002683 209 0.837
Mouse
immune effector process GO:0002252 321 0.826
Mouse
leukocyte differentiation GO:0002521 342 0.794
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.763
regulation of leukocyte mediated immunity GO:0002703 104 0.762
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.750
Mouse
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.735
Mouse
regulation of transferase activity GO:0051338 263 0.728
olfactory learning GO:0008355 2 0.711
myeloid leukocyte differentiation GO:0002573 119 0.704
leukocyte mediated immunity GO:0002443 174 0.698
Mouse
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.689
myeloid cell differentiation GO:0030099 233 0.689
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.665
regulation of protein secretion GO:0050708 82 0.653
Human
regulation of map kinase activity GO:0043405 120 0.642
Mouse
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.636
positive regulation of secretion by cell GO:1903532 114 0.613
Human
regulation of mast cell activation GO:0033003 21 0.605
regulation of protein kinase activity GO:0045859 232 0.600
myeloid leukocyte mediated immunity GO:0002444 42 0.597
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.594
regulation of kinase activity GO:0043549 249 0.586
regulation of mast cell activation involved in immune response GO:0033006 17 0.580
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.536
integrin mediated signaling pathway GO:0007229 27 0.533
myeloid leukocyte activation GO:0002274 83 0.523
regulated secretory pathway GO:0045055 32 0.522
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.521
positive regulation of leukocyte degranulation GO:0043302 10 0.514
positive regulation of protein kinase activity GO:0045860 144 0.509
regulation of response to wounding GO:1903034 189 0.500
negative regulation of phagocytosis GO:0050765 4 0.498
fatty acid metabolic process GO:0006631 121 0.496
regulation of t cell activation GO:0050863 170 0.488
small gtpase mediated signal transduction GO:0007264 97 0.470
activation of mapk activity GO:0000187 59 0.468
response to lipopolysaccharide GO:0032496 128 0.457
erk1 and erk2 cascade GO:0070371 77 0.445
actin filament organization GO:0007015 113 0.440
Fly
positive regulation of mapk cascade GO:0043410 170 0.436
regulation of lymphocyte activation GO:0051249 240 0.428
Mouse
negative regulation of cell activation GO:0050866 111 0.408
Mouse
metanephric glomerular epithelium development GO:0072244 3 0.400
t cell activation GO:0042110 289 0.389
Mouse
mast cell mediated immunity GO:0002448 20 0.373
leukocyte activation involved in immune response GO:0002366 126 0.368
metanephric glomerular epithelial cell development GO:0072313 2 0.365
cellular response to molecule of bacterial origin GO:0071219 83 0.347
leukocyte degranulation GO:0043299 27 0.347
negative regulation of cell proliferation GO:0008285 296 0.344
Mouse
positive regulation of transferase activity GO:0051347 167 0.343
regulation of cell migration GO:0030334 219 0.342
regulation of myeloid leukocyte differentiation GO:0002761 58 0.341
Rat
positive regulation of kinase activity GO:0033674 155 0.339
positive regulation of jun kinase activity GO:0043507 30 0.339
lymphocyte proliferation GO:0046651 164 0.331
Mouse
mast cell degranulation GO:0043303 19 0.328
negative regulation of mapk cascade GO:0043409 65 0.322
phosphatidylinositol mediated signaling GO:0048015 41 0.317
cytokine production GO:0001816 319 0.315
Human Mouse
regulation of endocytosis GO:0030100 69 0.312
regulation of cellular amine metabolic process GO:0033238 20 0.301
cellular response to peptide hormone stimulus GO:0071375 92 0.298
Fly
cellular lipid metabolic process GO:0044255 323 0.294
negative regulation of map kinase activity GO:0043407 34 0.293
positive regulation of immune effector process GO:0002699 107 0.293
regulation of cytokine production GO:0001817 266 0.289
Human
myeloid cell activation involved in immune response GO:0002275 34 0.288
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.288
positive regulation of lipid metabolic process GO:0045834 40 0.287
cell cell adhesion GO:0098609 41 0.284
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.284
cellular metal ion homeostasis GO:0006875 151 0.282
unsaturated fatty acid metabolic process GO:0033559 31 0.277
positive regulation of protein transport GO:0051222 93 0.277
Human
cellular ketone metabolic process GO:0042180 84 0.274
negative regulation of gluconeogenesis GO:0045721 9 0.268
detection of oxidative stress GO:0070994 1 0.266
regulation of adiponectin secretion GO:0070163 2 0.261
inflammatory response GO:0006954 244 0.260
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.258
b cell activation GO:0042113 161 0.256
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.256
cell substrate adhesion GO:0031589 130 0.255
positive regulation of protein phosphorylation GO:0001934 242 0.246
positive regulation of cellular component biogenesis GO:0044089 94 0.245
adaptive immune response GO:0002250 155 0.242
regulation of myeloid cell differentiation GO:0045637 96 0.239
Rat
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.238
regulation of adaptive immune response GO:0002819 90 0.238
metanephric glomerular epithelial cell differentiation GO:0072312 2 0.238
regulation of phagocytosis GO:0050764 33 0.236
extracellular structure organization GO:0043062 148 0.234
Mouse
kidney development GO:0001822 213 0.232
Mouse
regulation of blood coagulation GO:0030193 28 0.231
regulation of epithelial cell proliferation GO:0050678 141 0.227
Mouse
defense response to other organism GO:0098542 197 0.224
regulation of defense response GO:0031347 233 0.224
glomerulus development GO:0032835 40 0.223
Mouse
regulation of mapk cascade GO:0043408 248 0.218
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.218
actin cytoskeleton organization GO:0030036 220 0.218
neutrophil activation involved in immune response GO:0002283 8 0.212
positive regulation of map kinase activity GO:0043406 84 0.211
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.210
negative regulation of molecular function GO:0044092 258 0.209
carbohydrate biosynthetic process GO:0016051 74 0.205
leukocyte proliferation GO:0070661 172 0.205
Mouse
cerebellum development GO:0021549 77 0.204
mast cell activation involved in immune response GO:0002279 20 0.202
molting cycle GO:0042303 90 0.201
positive regulation of smooth muscle cell migration GO:0014911 4 0.198
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.197
Mouse Fly
regulation of intracellular transport GO:0032386 159 0.196
negative regulation of myeloid cell differentiation GO:0045638 38 0.195
positive regulation of protein secretion GO:0050714 52 0.193
Human
positive regulation of exocytosis GO:0045921 20 0.191
lipid modification GO:0030258 65 0.190
regulation of hormone secretion GO:0046883 88 0.187
oxidation reduction process GO:0055114 342 0.187
cellular response to lipopolysaccharide GO:0071222 77 0.187
regulation of inflammatory response GO:0050727 147 0.183
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.178
mammary gland epithelium development GO:0061180 65 0.177
anatomical structure homeostasis GO:0060249 145 0.174
Mouse Rat
positive regulation of protein kinase b signaling GO:0051897 32 0.173
regulation of production of molecular mediator of immune response GO:0002700 65 0.173
regulation of lipid metabolic process GO:0019216 118 0.173
defense response to bacterium GO:0042742 119 0.166
monocyte differentiation GO:0030224 9 0.166
renal filtration cell differentiation GO:0061318 10 0.162
defense response to virus GO:0051607 68 0.161
hexose metabolic process GO:0019318 98 0.160
renal system development GO:0072001 225 0.158
Mouse Fly
positive regulation of renal albumin absorption GO:2000534 1 0.156
protein secretion GO:0009306 111 0.156
Human
renal protein absorption GO:0097017 1 0.155
mapk cascade GO:0000165 281 0.154
cell matrix adhesion GO:0007160 68 0.154
positive regulation of intracellular transport GO:0032388 70 0.153
negative regulation of adaptive immune response GO:0002820 25 0.153
negative regulation of lymphocyte activation GO:0051250 91 0.152
Mouse
metanephric glomerular visceral epithelial cell differentiation GO:0072248 2 0.149
ras protein signal transduction GO:0007265 77 0.149
exocytosis GO:0006887 121 0.149
cell migration involved in metanephros development GO:0035788 2 0.147
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.146
cytokine production involved in immune response GO:0002367 34 0.145
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.144
Mouse Rat
positive regulation of cell motility GO:2000147 116 0.144
lysosome localization GO:0032418 20 0.143
regulation of secretion by cell GO:1903530 249 0.143
Human
cytokine secretion GO:0050663 72 0.142
Human
hexose biosynthetic process GO:0019319 39 0.142
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.141
regulation of protein serine threonine kinase activity GO:0071900 157 0.140
regulation of hormone levels GO:0010817 211 0.139
Mouse
cellular response to insulin stimulus GO:0032869 78 0.138
Fly
nephron development GO:0072006 109 0.138
Mouse
positive regulation of secretion GO:0051047 130 0.137
Human
detection of stimulus involved in sensory perception GO:0050906 44 0.137
Mouse
macrophage derived foam cell differentiation GO:0010742 6 0.136
positive regulation of leukocyte mediated immunity GO:0002705 70 0.133
positive regulation of cell migration GO:0030335 109 0.133
peptidyl tyrosine phosphorylation GO:0018108 143 0.133
carbohydrate metabolic process GO:0005975 230 0.133
unsaturated fatty acid biosynthetic process GO:0006636 15 0.133
regulation of secretion GO:0051046 274 0.131
Human
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.129
regulation of cellular amino acid metabolic process GO:0006521 5 0.128
single organism cell adhesion GO:0098602 156 0.126
Mouse
positive regulation of regulated secretory pathway GO:1903307 10 0.126
hematopoietic progenitor cell differentiation GO:0002244 143 0.125
Mouse
cellular chemical homeostasis GO:0055082 215 0.125
regulation of carbohydrate biosynthetic process GO:0043255 40 0.124
wound healing GO:0042060 157 0.124
Mouse
metanephric mesenchymal cell migration GO:0035789 2 0.123
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.123
positive regulation of metanephric glomerulus development GO:0072300 4 0.123
cellular response to biotic stimulus GO:0071216 92 0.122
leukocyte migration GO:0050900 124 0.122
Zebrafish
regulation of leukocyte proliferation GO:0070663 121 0.121
immunoglobulin mediated immune response GO:0016064 69 0.121
muscle cell differentiation GO:0042692 261 0.120
Mouse
negative regulation of hypersensitivity GO:0002884 3 0.120
cell chemotaxis GO:0060326 81 0.118
Zebrafish Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.117
toll like receptor 9 signaling pathway GO:0034162 6 0.115
negative regulation of protein modification process GO:0031400 163 0.115
endocytosis GO:0006897 168 0.114
monocarboxylic acid metabolic process GO:0032787 191 0.114
interleukin 3 production GO:0032632 3 0.113
negative regulation of phosphorus metabolic process GO:0010563 184 0.113
canonical wnt signaling pathway GO:0060070 130 0.113
hormone secretion GO:0046879 128 0.112
negative regulation of leukocyte proliferation GO:0070664 46 0.112
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.111
germ cell development GO:0007281 185 0.110
Mouse Fly
regulation of macrophage differentiation GO:0045649 9 0.110
positive regulation of jnk cascade GO:0046330 46 0.109
toll like receptor 7 signaling pathway GO:0034154 4 0.109
regulation of renin secretion into blood stream GO:1900133 4 0.109
myeloid cell homeostasis GO:0002262 114 0.109
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.108
Mouse
leukocyte chemotaxis GO:0030595 69 0.108
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 71 0.108
negative regulation of phosphorylation GO:0042326 166 0.108
gland development GO:0048732 330 0.107
Mouse Fly
monosaccharide metabolic process GO:0005996 106 0.107
positive regulation of glucose transport GO:0010828 16 0.105
spinal cord development GO:0021510 81 0.105
fibroblast proliferation GO:0048144 35 0.105
negative regulation of inflammatory response GO:0050728 61 0.104
regulation of actin filament length GO:0030832 45 0.104
positive regulation of behavior GO:0048520 40 0.103
Zebrafish Mouse
placenta development GO:0001890 140 0.103
negative regulation of type i hypersensitivity GO:0001811 1 0.102
epithelial cell development GO:0002064 159 0.101
Fly
hindbrain development GO:0030902 128 0.101
regulation of wnt signaling pathway GO:0030111 123 0.101
positive regulation of protein modification process GO:0031401 299 0.101
mast cell activation GO:0045576 27 0.099
adiponectin secretion GO:0070162 2 0.097
cerebellum morphogenesis GO:0021587 42 0.097
detection of stimulus GO:0051606 84 0.096
Mouse
striated muscle tissue development GO:0014706 293 0.096
Mouse Rat
regulation of establishment of protein localization GO:0070201 181 0.094
Human
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.094
endoderm development GO:0007492 45 0.094
amine metabolic process GO:0009308 45 0.094
osteoclast differentiation GO:0030316 62 0.093
regulation of cellular component biogenesis GO:0044087 181 0.092
phagocytosis GO:0006909 66 0.092
muscle tissue development GO:0060537 308 0.092
Mouse Rat
tissue remodeling GO:0048771 102 0.090
Mouse Rat
regulation of carbohydrate metabolic process GO:0006109 75 0.090
regulation of renal albumin absorption GO:2000532 1 0.090
ear development GO:0043583 200 0.090
positive regulation of metanephric glomerular visceral epithelial cell development GO:2000478 1 0.090
positive regulation of cell adhesion GO:0045785 80 0.089
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.089
negative regulation of protein phosphorylation GO:0001933 126 0.089
hemostasis GO:0007599 78 0.088
positive regulation of calcium mediated signaling GO:0050850 15 0.088
cognition GO:0050890 149 0.087
cell differentiation involved in kidney development GO:0061005 33 0.087
metencephalon development GO:0022037 89 0.086
response to peptide GO:1901652 136 0.086
Fly
regulation of lymphocyte proliferation GO:0050670 117 0.086
memory GO:0007613 58 0.086
receptor mediated endocytosis GO:0006898 51 0.086
regulation of system process GO:0044057 200 0.085
water homeostasis GO:0030104 27 0.085
negative regulation of lymphocyte proliferation GO:0050672 45 0.083
lymphocyte mediated immunity GO:0002449 139 0.082
cellular divalent inorganic cation homeostasis GO:0072503 127 0.081
negative regulation of cytokine production GO:0001818 84 0.081
positive regulation of camp dependent protein kinase activity GO:2000481 3 0.080
epidermis development GO:0008544 187 0.080
gonad development GO:0008406 141 0.080
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.080
regulation of type iia hypersensitivity GO:0001796 4 0.079
positive regulation of hormone secretion GO:0046887 38 0.079
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.078
Mouse
tissue homeostasis GO:0001894 115 0.078
Mouse Rat
regulation of cell motility GO:2000145 236 0.077
renal system process GO:0003014 48 0.077
glomerular epithelial cell development GO:0072310 6 0.076
cell migration involved in kidney development GO:0035787 3 0.076
Mouse
response to molecule of bacterial origin GO:0002237 143 0.075
regulation of gluconeogenesis GO:0006111 30 0.075
protein heterotrimerization GO:0070208 8 0.075
positive regulation of cytokine secretion GO:0050715 41 0.075
Human
response to steroid hormone GO:0048545 56 0.074
macrophage activation GO:0042116 27 0.074
activation of jun kinase activity GO:0007257 15 0.074
negative regulation of defense response GO:0031348 77 0.073
female gamete generation GO:0007292 74 0.073
Fly
fc epsilon receptor signaling pathway GO:0038095 3 0.073
single organismal cell cell adhesion GO:0016337 131 0.072
Mouse
positive regulation of synapse assembly GO:0051965 18 0.072
hair follicle morphogenesis GO:0031069 29 0.072
regulation of organelle organization GO:0033043 289 0.072
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.072
negative regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000584 2 0.072
positive regulation of wnt signaling pathway GO:0030177 45 0.072
maintenance of location GO:0051235 89 0.071
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 6 0.070
negative regulation of metanephric mesenchymal cell migration GO:2000590 1 0.069
chemotaxis GO:0006935 247 0.069
Zebrafish Mouse
hair cycle GO:0042633 90 0.069
regulation of t cell proliferation GO:0042129 92 0.069
immunoglobulin production GO:0002377 73 0.069
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.069
monosaccharide transport GO:0015749 58 0.069
peptidyl amino acid modification GO:0018193 336 0.068
immune response inhibiting cell surface receptor signaling pathway GO:0002767 3 0.068
regulation of jnk cascade GO:0046328 62 0.068
monocarboxylic acid catabolic process GO:0072329 27 0.068
regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000583 2 0.067
small molecule biosynthetic process GO:0044283 132 0.065
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.065
calcium mediated signaling GO:0019722 46 0.065
body morphogenesis GO:0010171 45 0.065
Mouse
positive regulation of macrophage differentiation GO:0045651 5 0.065
learning or memory GO:0007611 148 0.065
regulation of jak stat cascade GO:0046425 34 0.064
positive regulation of protein localization to nucleus GO:1900182 30 0.064
bmp signaling pathway GO:0030509 93 0.064
Mouse
hormone biosynthetic process GO:0042446 16 0.063
cell activation involved in immune response GO:0002263 126 0.063
negative regulation of cellular component organization GO:0051129 194 0.063
cerebellar cortex development GO:0021695 48 0.063
neutrophil activation GO:0042119 9 0.063
regulation of protein localization GO:0032880 231 0.062
Human
cellularization GO:0007349 1 0.062
regulation of protein transport GO:0051223 163 0.061
Human
morphogenesis of a branching structure GO:0001763 203 0.061
Mouse
sensory perception GO:0007600 245 0.061
Mouse
positive regulation of type iii hypersensitivity GO:0001805 3 0.061
epidermis morphogenesis GO:0048730 33 0.060
positive regulation of phagocytosis GO:0050766 26 0.059
regulation of metanephros development GO:0072215 15 0.059
Mouse
toll like receptor signaling pathway GO:0002224 38 0.059
regulation of jun kinase activity GO:0043506 40 0.059
protein activation cascade GO:0072376 19 0.059
protein heterooligomerization GO:0051291 14 0.059
metanephric nephron development GO:0072210 34 0.059
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.059
lymphocyte differentiation GO:0030098 242 0.059
Mouse
blood coagulation GO:0007596 76 0.058
cellular homeostasis GO:0019725 240 0.058
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.058
positive regulation of glomerulus development GO:0090193 5 0.058
defecation GO:0030421 1 0.058
organic anion transport GO:0015711 137 0.058
hormone metabolic process GO:0042445 86 0.057
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.057
regulation of homeostatic process GO:0032844 182 0.056
Rat
tolerance induction to self antigen GO:0002513 4 0.056
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.056
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.056
regulation of clathrin mediated endocytosis GO:2000369 4 0.056
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.055
leukocyte apoptotic process GO:0071887 71 0.055
lipid biosynthetic process GO:0008610 179 0.055
calcium ion homeostasis GO:0055074 127 0.055
Mouse
axon guidance GO:0007411 141 0.055
positive regulation of leukocyte proliferation GO:0070665 73 0.055
antigen processing and presentation of exogenous peptide antigen via mhc class i GO:0042590 6 0.055
negative regulation of t cell proliferation GO:0042130 38 0.054
negative regulation of metanephros development GO:0072217 6 0.053
dna metabolic process GO:0006259 303 0.053
Mouse
response to organonitrogen compound GO:0010243 246 0.053
Mouse Fly
immune response activating signal transduction GO:0002757 116 0.053
protein localization to organelle GO:0033365 185 0.053
inositol lipid mediated signaling GO:0048017 41 0.053
central nervous system neuron differentiation GO:0021953 162 0.053
glycoprotein metabolic process GO:0009100 116 0.052
fatty acid biosynthetic process GO:0006633 41 0.052
glucose import GO:0046323 32 0.052
negative regulation of carbohydrate metabolic process GO:0045912 19 0.052
carboxylic acid biosynthetic process GO:0046394 86 0.052
development of primary sexual characteristics GO:0045137 143 0.052
Mouse
positive regulation of cytokine production GO:0001819 174 0.052
Human
positive regulation of exit from mitosis GO:0031536 1 0.052
synapse organization GO:0050808 125 0.051
positive regulation of lipid kinase activity GO:0090218 11 0.051
regulation of dendritic cell apoptotic process GO:2000668 3 0.051
organic hydroxy compound transport GO:0015850 93 0.051
regulation of regulated secretory pathway GO:1903305 20 0.050
calcium ion transport GO:0006816 159 0.050
Mouse
fatty acid derivative metabolic process GO:1901568 33 0.050
glucose transport GO:0015758 56 0.050
regulation of cellular response to stress GO:0080135 159 0.049
alpha beta t cell activation GO:0046631 91 0.049
positive regulation of endocytosis GO:0045807 42 0.049
lymphocyte homeostasis GO:0002260 64 0.049
epithelium migration GO:0090132 63 0.049
Mouse Fly
stress activated mapk cascade GO:0051403 80 0.048
fatty acid beta oxidation GO:0006635 16 0.048
regulation of phospholipase c activity GO:1900274 3 0.048
positive regulation of stem cell differentiation GO:2000738 23 0.048
locomotory behavior GO:0007626 195 0.047
embryonic placenta development GO:0001892 98 0.047
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.047
wnt signaling pathway GO:0016055 188 0.047
divalent inorganic cation transport GO:0072511 178 0.047
Mouse
positive regulation of mast cell degranulation GO:0043306 10 0.046
i kappab kinase nf kappab signaling GO:0007249 85 0.046
negative regulation of fat cell differentiation GO:0045599 36 0.046
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.046
salivary gland morphogenesis GO:0007435 33 0.046
Fly
leukotriene metabolic process GO:0006691 7 0.046
regulation of cytoplasmic transport GO:1903649 112 0.045
negative regulation of phosphate metabolic process GO:0045936 184 0.045
regionalization GO:0003002 337 0.045
regulation of glucose transport GO:0010827 32 0.045
lipid catabolic process GO:0016042 69 0.045
negative regulation of apoptotic signaling pathway GO:2001234 104 0.045
hindbrain morphogenesis GO:0021575 46 0.045
regulation of kidney development GO:0090183 40 0.044
Mouse
mucopolysaccharide metabolic process GO:1903510 25 0.044
carbohydrate homeostasis GO:0033500 128 0.044
positive regulation of response to wounding GO:1903036 66 0.044
platelet degranulation GO:0002576 6 0.044
cerebellar granular layer formation GO:0021684 9 0.044
mammary gland duct morphogenesis GO:0060603 38 0.044
gluconeogenesis GO:0006094 39 0.044
lipid localization GO:0010876 126 0.044
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.044
regulation of immunoglobulin mediated immune response GO:0002889 37 0.043
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.043
positive regulation of fatty acid metabolic process GO:0045923 8 0.043
response to transforming growth factor beta GO:0071559 88 0.043
cellular amino acid metabolic process GO:0006520 103 0.043
regulation of mast cell degranulation GO:0043304 16 0.043
anion transport GO:0006820 177 0.043
protein catabolic process GO:0030163 221 0.042
negative regulation of nervous system development GO:0051961 156 0.042
regulation of canonical wnt signaling pathway GO:0060828 82 0.042
protein oligomerization GO:0051259 67 0.042
regulation of anatomical structure size GO:0090066 178 0.041
regulation of stem cell proliferation GO:0072091 78 0.041
Mouse
cellular response to hormone stimulus GO:0032870 150 0.041
Mouse Fly
actin cytoskeleton reorganization GO:0031532 21 0.041
skin development GO:0043588 220 0.041
t cell differentiation GO:0030217 174 0.041
Mouse
negative regulation of leukocyte mediated immunity GO:0002704 29 0.041
negative regulation of granulocyte differentiation GO:0030853 3 0.041
t cell proliferation GO:0042098 120 0.041
regulation of calcium mediated signaling GO:0050848 19 0.041
response to oxidative stress GO:0006979 123 0.041
protein homooligomerization GO:0051260 43 0.040
regulation of actin cytoskeleton organization GO:0032956 84 0.040
posttranscriptional regulation of gene expression GO:0010608 155 0.040
osteoclast development GO:0036035 9 0.040
Zebrafish
substrate adhesion dependent cell spreading GO:0034446 30 0.040
negative regulation of b cell activation GO:0050869 27 0.040
Mouse
proteoglycan metabolic process GO:0006029 38 0.039
b cell mediated immunity GO:0019724 71 0.039
epithelial cell differentiation involved in kidney development GO:0035850 23 0.039
glucose homeostasis GO:0042593 128 0.039
cell cell junction organization GO:0045216 72 0.039
Human
superoxide anion generation GO:0042554 11 0.039
positive regulation of adaptive immune response GO:0002821 61 0.039
positive regulation of t cell activation GO:0050870 101 0.039
metal ion homeostasis GO:0055065 189 0.039
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.038
positive regulation of cell activation GO:0050867 158 0.038
organic acid biosynthetic process GO:0016053 86 0.038
carboxylic acid catabolic process GO:0046395 51 0.038
regulation of blood pressure GO:0008217 93 0.038
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.038
rho protein signal transduction GO:0007266 32 0.038
camera type eye development GO:0043010 266 0.038
Zebrafish Mouse
monocarboxylic acid biosynthetic process GO:0072330 61 0.037
myeloid leukocyte migration GO:0097529 57 0.037
Zebrafish
positive regulation of adiponectin secretion GO:0070165 1 0.037
response to nutrient levels GO:0031667 109 0.037
positive regulation of intracellular protein transport GO:0090316 42 0.037
organelle localization GO:0051640 179 0.037
lens development in camera type eye GO:0002088 62 0.037
regulation of calcium ion transport into cytosol GO:0010522 31 0.036
regulation of cytoskeleton organization GO:0051493 122 0.036
positive regulation of defense response GO:0031349 124 0.036
actin polymerization or depolymerization GO:0008154 54 0.036
immune response regulating signaling pathway GO:0002764 125 0.036
granulocyte activation GO:0036230 10 0.036
divalent inorganic cation homeostasis GO:0072507 138 0.036
Mouse
multicellular organismal homeostasis GO:0048871 164 0.036
Mouse Rat
circadian rhythm GO:0007623 114 0.036
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 8 0.035
response to corticosteroid GO:0031960 20 0.035
response to retinoic acid GO:0032526 56 0.035
negative regulation of immune effector process GO:0002698 55 0.035
response to glucocorticoid GO:0051384 20 0.035

Csf1r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.986
musculoskeletal system disease DOID:17 0 0.986
connective tissue disease DOID:65 0 0.986
bone disease DOID:0080001 0 0.826
bone remodeling disease DOID:0080005 0 0.636
osteopetrosis DOID:13533 0 0.636
osteosclerosis DOID:4254 0 0.636
immune system disease DOID:2914 0 0.190
nervous system disease DOID:863 0 0.128
sensory system disease DOID:0050155 0 0.086
lupus erythematosus DOID:8857 0 0.063
hypersensitivity reaction disease DOID:0060056 0 0.063
hypersensitivity reaction type ii disease DOID:417 0 0.063
disease by infectious agent DOID:0050117 0 0.040