Mus musculus

0 known processes

Cst3

cystatin C

(Aliases: CysC)

Cst3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
apoptotic signaling pathway GO:0097190 306 0.287
protein processing GO:0016485 163 0.265
Human
negative regulation of protein metabolic process GO:0051248 282 0.242
Human Rat
regulation of hydrolase activity GO:0051336 246 0.221
Human Rat
positive regulation of cell death GO:0010942 224 0.218
regulation of peptidase activity GO:0052547 96 0.194
Human Rat
positive regulation of programmed cell death GO:0043068 218 0.183
negative regulation of proteolysis GO:0045861 74 0.179
Human Rat
negative regulation of cellular protein metabolic process GO:0032269 247 0.159
Human Rat
regulation of endopeptidase activity GO:0052548 89 0.155
Human
positive regulation of apoptotic process GO:0043065 217 0.145
neuronal action potential GO:0019228 54 0.141
regulation of apoptotic signaling pathway GO:2001233 197 0.140
multicellular organismal signaling GO:0035637 91 0.136
regulation of cell motility GO:2000145 236 0.132
negative regulation of protein processing GO:0010955 79 0.119
Human Rat
regulation of membrane potential GO:0042391 192 0.107
regulation of proteolysis GO:0030162 164 0.105
Human Rat
response to hepatocyte growth factor GO:0035728 2 0.102
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.101
regulation of cellular amino acid metabolic process GO:0006521 5 0.099
regulation of protein maturation GO:1903317 96 0.097
Human Rat
extrinsic apoptotic signaling pathway GO:0097191 126 0.095
regulation of binding GO:0051098 111 0.090
regulation of cell projection organization GO:0031344 206 0.084
microglia development GO:0014005 2 0.081
negative regulation of cell proliferation GO:0008285 296 0.075
extracellular structure organization GO:0043062 148 0.075
Human
response to radiation GO:0009314 165 0.073
positive regulation of cellular amine metabolic process GO:0033240 5 0.073
regulation of neuron projection development GO:0010975 169 0.073
circulatory system process GO:0003013 197 0.071
actin cytoskeleton organization GO:0030036 220 0.068
protein maturation GO:0051604 176 0.066
Human
skeletal muscle organ development GO:0060538 163 0.065
action potential GO:0001508 78 0.065
muscle tissue development GO:0060537 308 0.065
cellular metal ion homeostasis GO:0006875 151 0.064
cellular component assembly involved in morphogenesis GO:0010927 139 0.064
ensheathment of neurons GO:0007272 76 0.064
cation homeostasis GO:0055080 212 0.062
negative regulation of molecular function GO:0044092 258 0.060
Human Rat
wound healing GO:0042060 157 0.060
immune effector process GO:0002252 321 0.059
metal ion homeostasis GO:0055065 189 0.058
positive regulation of apoptotic signaling pathway GO:2001235 95 0.057
cellular ketone metabolic process GO:0042180 84 0.055
myelination GO:0042552 74 0.054
regulation of transferase activity GO:0051338 263 0.054
cellular amine metabolic process GO:0044106 44 0.054
cellular chemical homeostasis GO:0055082 215 0.052
microglia differentiation GO:0014004 2 0.051
lipid catabolic process GO:0016042 69 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
amine metabolic process GO:0009308 45 0.049
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.049
regulation of neuron differentiation GO:0045664 281 0.049
multi multicellular organism process GO:0044706 109 0.049
Rat
macromolecule catabolic process GO:0009057 281 0.046
Human
negative regulation of protein maturation GO:1903318 79 0.046
Human Rat
regulation of protein processing GO:0070613 96 0.045
Human Rat
cellular response to growth factor stimulus GO:0071363 197 0.045
carbohydrate derivative catabolic process GO:1901136 231 0.045
Human
regulation of voltage gated calcium channel activity GO:1901385 4 0.045
response to organic cyclic compound GO:0014070 198 0.044
Rat
cellular amino acid metabolic process GO:0006520 103 0.044
inflammatory response GO:0006954 244 0.043
membrane organization GO:0061024 245 0.043
fertilization GO:0009566 127 0.042
dna metabolic process GO:0006259 303 0.041
Rat
transmembrane transport GO:0055085 412 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.041
negative regulation of neuron differentiation GO:0045665 101 0.039
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.039
cellular ion homeostasis GO:0006873 165 0.039
cellular response to oxidative stress GO:0034599 76 0.038
Rat
chemotaxis GO:0006935 247 0.037
leukocyte differentiation GO:0002521 342 0.037
axon ensheathment GO:0008366 76 0.036
t cell activation GO:0042110 289 0.036
signal transduction in absence of ligand GO:0038034 55 0.036
transmission of nerve impulse GO:0019226 76 0.035
cell chemotaxis GO:0060326 81 0.035
regulation of mapk cascade GO:0043408 248 0.035
coagulation GO:0050817 78 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
peptidyl amino acid modification GO:0018193 336 0.033
cellular homeostasis GO:0019725 240 0.033
positive regulation of secretion GO:0051047 130 0.033
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.033
cellular divalent inorganic cation homeostasis GO:0072503 127 0.033
regulation of secretion GO:0051046 274 0.032
leukocyte activation involved in immune response GO:0002366 126 0.032
single fertilization GO:0007338 82 0.032
negative regulation of osteoblast proliferation GO:0033689 4 0.031
calcium ion homeostasis GO:0055074 127 0.031
positive regulation of nervous system development GO:0051962 221 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
Human
regulation of cysteine type endopeptidase activity GO:2000116 65 0.030
regulation of cell cycle GO:0051726 281 0.029
regulation of hormone levels GO:0010817 211 0.029
negative regulation of glycoprotein metabolic process GO:1903019 3 0.029
Human
regulation of cell migration GO:0030334 219 0.029
regulation of protein binding GO:0043393 60 0.028
cation transport GO:0006812 399 0.028
male gamete generation GO:0048232 285 0.028
negative regulation of peptidase activity GO:0010466 46 0.028
Human Rat
organophosphate biosynthetic process GO:0090407 122 0.027
leukocyte proliferation GO:0070661 172 0.027
glial cell development GO:0021782 54 0.027
muscle contraction GO:0006936 101 0.027
response to oxidative stress GO:0006979 123 0.026
Rat
gliogenesis GO:0042063 141 0.026
myeloid cell differentiation GO:0030099 233 0.026
cytokine production GO:0001816 319 0.026
regulation of system process GO:0044057 200 0.026
maintenance of location GO:0051235 89 0.026
positive regulation of mapk cascade GO:0043410 170 0.026
membrane lipid metabolic process GO:0006643 53 0.026
negative regulation of protein modification process GO:0031400 163 0.025
hemostasis GO:0007599 78 0.024
innate immune response GO:0045087 157 0.024
negative regulation of cellular catabolic process GO:0031330 47 0.024
Human
leukocyte mediated immunity GO:0002443 174 0.024
mapk cascade GO:0000165 281 0.024
oxidation reduction process GO:0055114 342 0.024
negative regulation of hydrolase activity GO:0051346 71 0.023
Human Rat
urogenital system development GO:0001655 261 0.023
cell activation involved in immune response GO:0002263 126 0.023
regulation of defense response GO:0031347 233 0.023
response to light stimulus GO:0009416 135 0.023
cellular calcium ion homeostasis GO:0006874 119 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
i kappab kinase nf kappab signaling GO:0007249 85 0.023
actin filament severing GO:0051014 1 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
oligodendrocyte differentiation GO:0048709 53 0.022
angiogenesis GO:0001525 201 0.022
cellular protein catabolic process GO:0044257 155 0.022
learning or memory GO:0007611 148 0.022
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.022
protein localization to plasma membrane GO:0072659 57 0.022
positive regulation of neuron projection development GO:0010976 79 0.022
microtubule based process GO:0007017 236 0.022
spermatogenesis GO:0007283 284 0.022
regulation of response to wounding GO:1903034 189 0.021
defense response to other organism GO:0098542 197 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.021
regulation of map kinase activity GO:0043405 120 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
divalent metal ion transport GO:0070838 172 0.020
muscle system process GO:0003012 141 0.020
blood coagulation GO:0007596 76 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
cell recognition GO:0008037 83 0.020
positive regulation of cell development GO:0010720 237 0.020
striated muscle tissue development GO:0014706 293 0.020
amyloid precursor protein biosynthetic process GO:0042983 3 0.020
striated muscle contraction GO:0006941 45 0.020
nitrogen compound transport GO:0071705 271 0.019
regulation of body fluid levels GO:0050878 162 0.019
response to inorganic substance GO:0010035 96 0.019
Rat
ribose phosphate metabolic process GO:0019693 291 0.019
regulation of beta amyloid clearance GO:1900221 1 0.019
defense response to gram positive bacterium GO:0050830 50 0.019
positive regulation of cell adhesion GO:0045785 80 0.019
regulation of protein kinase activity GO:0045859 232 0.019
adult locomotory behavior GO:0008344 91 0.019
divalent inorganic cation transport GO:0072511 178 0.019
kidney development GO:0001822 213 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
heart process GO:0003015 94 0.018
endocytosis GO:0006897 168 0.018
heterocycle catabolic process GO:0046700 280 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
necrotic cell death GO:0070265 30 0.018
regulation of cell activation GO:0050865 289 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
positive regulation of protein modification process GO:0031401 299 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
placenta development GO:0001890 140 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
lymphocyte proliferation GO:0046651 164 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
cellular protein complex assembly GO:0043623 116 0.017
blood vessel morphogenesis GO:0048514 285 0.017
detection of abiotic stimulus GO:0009582 60 0.017
lipid localization GO:0010876 126 0.017
organic hydroxy compound transport GO:0015850 93 0.016
lipoprotein metabolic process GO:0042157 43 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
response to peptide hormone GO:0043434 127 0.016
regulation of transmembrane transport GO:0034762 128 0.016
endomembrane system organization GO:0010256 147 0.016
activation of adenylate cyclase activity GO:0007190 4 0.016
astrocyte development GO:0014002 12 0.016
regulation of kinase activity GO:0043549 249 0.016
negative regulation of neuron projection development GO:0010977 50 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
cognition GO:0050890 149 0.016
cardiac muscle contraction GO:0060048 32 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of synaptic plasticity GO:0048167 87 0.016
morphogenesis of a branching structure GO:0001763 203 0.015
positive regulation of transferase activity GO:0051347 167 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
substantia nigra development GO:0021762 2 0.015
glycoprotein metabolic process GO:0009100 116 0.015
Human
sequestering of metal ion GO:0051238 19 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
negative regulation of response to wounding GO:1903035 77 0.015
visual behavior GO:0007632 45 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
response to organonitrogen compound GO:0010243 246 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
renal system development GO:0072001 225 0.015
regulation of intracellular transport GO:0032386 159 0.015
negative regulation of cell growth GO:0030308 44 0.015
positive regulation of cell migration GO:0030335 109 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
positive regulation of defense response GO:0031349 124 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
ossification GO:0001503 216 0.015
glial cell differentiation GO:0010001 131 0.015
protein localization to membrane GO:0072657 108 0.015
negative regulation of cell development GO:0010721 169 0.015
germ cell development GO:0007281 185 0.014
protein catabolic process GO:0030163 221 0.014
Human
sphingolipid metabolic process GO:0006665 45 0.014
camera type eye development GO:0043010 266 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
purine containing compound metabolic process GO:0072521 311 0.014
cardiocyte differentiation GO:0035051 87 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
neuron apoptotic process GO:0051402 142 0.014
lipid biosynthetic process GO:0008610 179 0.014
calcium ion transport GO:0006816 159 0.014
organelle assembly GO:0070925 177 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
Human
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of protein localization GO:0032880 231 0.014
positive regulation of kinase activity GO:0033674 155 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
blood circulation GO:0008015 195 0.014
response to extracellular stimulus GO:0009991 127 0.014
Rat
schwann cell differentiation GO:0014037 26 0.014
response to lipopolysaccharide GO:0032496 128 0.013
cardiac muscle cell differentiation GO:0055007 69 0.013
liposaccharide metabolic process GO:1903509 27 0.013
negative regulation of cell projection organization GO:0031345 56 0.013
adult behavior GO:0030534 135 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
sensory system development GO:0048880 3 0.013
positive regulation of protein export from nucleus GO:0046827 4 0.013
learning GO:0007612 98 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
sensory perception GO:0007600 245 0.013
ketone catabolic process GO:0042182 3 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
antigen processing and presentation GO:0019882 47 0.013
mitotic cell cycle GO:0000278 195 0.013
organic acid biosynthetic process GO:0016053 86 0.013
cholesterol homeostasis GO:0042632 44 0.013
astrocyte differentiation GO:0048708 43 0.013
regulation of wound healing GO:0061041 40 0.013
regulation of heart contraction GO:0008016 77 0.013
cation transmembrane transport GO:0098655 266 0.013
tissue migration GO:0090130 68 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
hormone secretion GO:0046879 128 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
leukocyte migration GO:0050900 124 0.013
response to peptide GO:1901652 136 0.013
regulation of cell cycle process GO:0010564 160 0.013
skeletal system development GO:0001501 356 0.013
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.013
plasma membrane organization GO:0007009 90 0.013
engulfment of apoptotic cell GO:0043652 3 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
leukocyte chemotaxis GO:0030595 69 0.012
extracellular matrix organization GO:0030198 147 0.012
Human
positive regulation of homeostatic process GO:0032846 64 0.012
beta amyloid clearance GO:0097242 2 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
digestive tract morphogenesis GO:0048546 147 0.012
defense response to bacterium GO:0042742 119 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
response to monosaccharide GO:0034284 67 0.012
negative regulation of growth GO:0045926 99 0.012
modulation by virus of host process GO:0019054 2 0.012
cellular response to external stimulus GO:0071496 88 0.012
interspecies interaction between organisms GO:0044419 83 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.012
positive regulation of cell motility GO:2000147 116 0.012
epithelium migration GO:0090132 63 0.012
positive regulation of cytokine production GO:0001819 174 0.012
regulation of protein transport GO:0051223 163 0.012
negative regulation of kinase activity GO:0033673 81 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
regulation of organelle organization GO:0033043 289 0.012
sensory organ morphogenesis GO:0090596 242 0.011
protein localization to organelle GO:0033365 185 0.011
gland development GO:0048732 330 0.011
Rat
regulation of protein catabolic process GO:0042176 108 0.011
Human
mitochondrion organization GO:0007005 134 0.011
cell type specific apoptotic process GO:0097285 268 0.011
cellular lipid catabolic process GO:0044242 52 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
negative regulation of nervous system development GO:0051961 156 0.011
ear development GO:0043583 200 0.011
regulation of ion transport GO:0043269 215 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
negative regulation of cellular amide metabolic process GO:0034249 4 0.011
t cell proliferation GO:0042098 120 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
response to muscle stretch GO:0035994 1 0.011
water soluble vitamin biosynthetic process GO:0042364 3 0.011
intracellular protein transport GO:0006886 204 0.011
establishment of protein localization to plasma membrane GO:0090002 34 0.011
l ascorbic acid metabolic process GO:0019852 4 0.011
regulation of chemotaxis GO:0050920 53 0.011
autophagy GO:0006914 45 0.011
bone development GO:0060348 120 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of killing of cells of other organism GO:0051709 4 0.011
positive regulation of behavior GO:0048520 40 0.011
glycolipid metabolic process GO:0006664 25 0.011
glucose homeostasis GO:0042593 128 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
protein kinase b signaling GO:0043491 74 0.011
positive regulation of necrotic cell death GO:0010940 1 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
response to metal ion GO:0010038 47 0.011
muscle cell development GO:0055001 133 0.010
cholesterol transport GO:0030301 38 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
metanephric glomerular epithelial cell differentiation GO:0072312 2 0.010
regulation of ossification GO:0030278 112 0.010
rhodopsin mediated signaling pathway GO:0016056 4 0.010
endothelial cell migration GO:0043542 44 0.010
cytoplasmic transport GO:0016482 234 0.010
cyclic nucleotide metabolic process GO:0009187 59 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
regulation of amyloid precursor protein biosynthetic process GO:0042984 3 0.010
organelle fission GO:0048285 170 0.010
cell matrix adhesion GO:0007160 68 0.010
regulation of inflammatory response GO:0050727 147 0.010
regulation of angiogenesis GO:0045765 81 0.010
epithelial cell development GO:0002064 159 0.010
Rat
corticosterone secretion GO:0035934 3 0.010
muscle cell differentiation GO:0042692 261 0.010
peripheral nervous system development GO:0007422 53 0.010
lateral line system development GO:0048925 1 0.010

Cst3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.347
Human
nervous system disease DOID:863 0 0.118
Human
disease of anatomical entity DOID:7 0 0.118
Human
central nervous system disease DOID:331 0 0.094
immune system disease DOID:2914 0 0.085
inherited metabolic disorder DOID:655 0 0.072
lipid storage disease DOID:9455 0 0.059
lysosomal storage disease DOID:3211 0 0.059
sphingolipidosis DOID:1927 0 0.059
acquired metabolic disease DOID:0060158 0 0.052
Human
sensory system disease DOID:0050155 0 0.030
Human
hematopoietic system disease DOID:74 0 0.027
connective tissue disease DOID:65 0 0.023
musculoskeletal system disease DOID:17 0 0.023
primary immunodeficiency disease DOID:612 0 0.015
brain disease DOID:936 0 0.014
cerebral degeneration DOID:1443 0 0.014
lymphatic system disease DOID:75 0 0.012
disease of mental health DOID:150 0 0.011