Mus musculus

38 known processes

Ctsd

cathepsin D

(Aliases: CatD,CD)

Ctsd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sphingolipid metabolic process GO:0006665 45 0.638
cellular lipid catabolic process GO:0044242 52 0.634
natural killer cell degranulation GO:0043320 3 0.516
multicellular organismal catabolic process GO:0044243 7 0.411
autophagy GO:0006914 45 0.405
positive regulation of necrotic cell death GO:0010940 1 0.400
cellular lipid metabolic process GO:0044255 323 0.364
natural killer cell activation involved in immune response GO:0002323 10 0.349
regulation of natural killer cell activation GO:0032814 22 0.334
pigmentation GO:0043473 71 0.321
metal ion homeostasis GO:0055065 189 0.318
cellular response to thyroid hormone stimulus GO:0097067 1 0.281
apoptotic signaling pathway GO:0097190 306 0.252
vacuole organization GO:0007033 38 0.241
glycosphingolipid catabolic process GO:0046479 5 0.235
endocytosis GO:0006897 168 0.227
macromolecule catabolic process GO:0009057 281 0.224
maintenance of location GO:0051235 89 0.209
response to organic cyclic compound GO:0014070 198 0.206
striated muscle tissue development GO:0014706 293 0.201
cellular macromolecule catabolic process GO:0044265 206 0.199
regulation of secretion GO:0051046 274 0.197
glycolipid metabolic process GO:0006664 25 0.196
organelle assembly GO:0070925 177 0.195
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.185
skeletal muscle organ development GO:0060538 163 0.173
ceramide biosynthetic process GO:0046513 20 0.159
divalent inorganic cation transport GO:0072511 178 0.155
male gamete generation GO:0048232 285 0.153
response to peptide GO:1901652 136 0.144
collagen catabolic process GO:0030574 6 0.142
lipid catabolic process GO:0016042 69 0.140
collagen metabolic process GO:0032963 17 0.139
lysosome organization GO:0007040 21 0.138
cellular homeostasis GO:0019725 240 0.137
placenta development GO:0001890 140 0.137
maternal process involved in female pregnancy GO:0060135 32 0.135
response to inorganic substance GO:0010035 96 0.132
cation transport GO:0006812 399 0.130
multicellular organismal macromolecule metabolic process GO:0044259 19 0.130
tissue regeneration GO:0042246 22 0.122
multi multicellular organism process GO:0044706 109 0.122
muscle tissue development GO:0060537 308 0.120
regulation of neuron apoptotic process GO:0043523 122 0.117
regulation of secretion by cell GO:1903530 249 0.114
maternal placenta development GO:0001893 20 0.112
calcium ion transport GO:0006816 159 0.111
microtubule based process GO:0007017 236 0.106
response to oxidative stress GO:0006979 123 0.105
wound healing GO:0042060 157 0.102
cellular calcium ion homeostasis GO:0006874 119 0.102
response to interleukin 4 GO:0070670 23 0.102
carboxylic acid catabolic process GO:0046395 51 0.098
cellular metal ion homeostasis GO:0006875 151 0.098
carbohydrate catabolic process GO:0016052 32 0.097
protein catabolic process GO:0030163 221 0.096
cellular response to oxidative stress GO:0034599 76 0.096
regulation of peptidase activity GO:0052547 96 0.094
regulation of ion transport GO:0043269 215 0.087
response to monosaccharide GO:0034284 67 0.083
calcium ion homeostasis GO:0055074 127 0.082
oxidation reduction process GO:0055114 342 0.080
small molecule catabolic process GO:0044282 71 0.079
multicellular organismal aging GO:0010259 24 0.078
Worm
multicellular organismal metabolic process GO:0044236 28 0.078
lytic vacuole organization GO:0080171 21 0.075
lipid storage GO:0019915 36 0.073
ceramide metabolic process GO:0006672 31 0.072
myelination GO:0042552 74 0.071
cellular response to abiotic stimulus GO:0071214 56 0.070
cellular amino acid metabolic process GO:0006520 103 0.069
neuronal action potential GO:0019228 54 0.068
cation homeostasis GO:0055080 212 0.067
innate immune response GO:0045087 157 0.066
negative regulation of homeostatic process GO:0032845 71 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.065
leukocyte mediated immunity GO:0002443 174 0.062
negative regulation of neuron death GO:1901215 98 0.061
cellular response to external stimulus GO:0071496 88 0.061
regulation of cell shape GO:0008360 39 0.060
membrane lipid metabolic process GO:0006643 53 0.059
regeneration GO:0031099 38 0.059
regulation of hydrolase activity GO:0051336 246 0.058
spermatogenesis GO:0007283 284 0.058
protein processing GO:0016485 163 0.058
Mouse
developmental maturation GO:0021700 193 0.058
Mouse
glycerolipid metabolic process GO:0046486 122 0.057
glycosylceramide metabolic process GO:0006677 4 0.057
response to amine GO:0014075 16 0.055
regulation of hormone levels GO:0010817 211 0.054
Mouse
oligosaccharide catabolic process GO:0009313 2 0.053
ion transmembrane transport GO:0034220 361 0.053
sequestering of metal ion GO:0051238 19 0.052
membrane lipid catabolic process GO:0046466 8 0.052
sensory system development GO:0048880 3 0.051
regulation of cell motility GO:2000145 236 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.050
response to peptide hormone GO:0043434 127 0.049
negative regulation of proteolysis GO:0045861 74 0.049
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.049
regulation of mapk cascade GO:0043408 248 0.049
carbohydrate derivative catabolic process GO:1901136 231 0.048
leukocyte differentiation GO:0002521 342 0.048
cellular response to hormone stimulus GO:0032870 150 0.048
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.048
positive regulation of lymphocyte activation GO:0051251 140 0.048
response to organonitrogen compound GO:0010243 246 0.048
cellular component assembly involved in morphogenesis GO:0010927 139 0.047
regulation of proteolysis GO:0030162 164 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
positive regulation of macroautophagy GO:0016239 3 0.046
glycolipid catabolic process GO:0019377 5 0.045
angiogenesis GO:0001525 201 0.045
positive regulation of cell death GO:0010942 224 0.045
lipid modification GO:0030258 65 0.044
cellular chemical homeostasis GO:0055082 215 0.044
positive regulation of homeostatic process GO:0032846 64 0.043
response to ethanol GO:0045471 18 0.043
protein maturation GO:0051604 176 0.043
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.043
inflammatory response GO:0006954 244 0.042
cellular protein catabolic process GO:0044257 155 0.042
negative regulation of intracellular signal transduction GO:1902532 167 0.042
ensheathment of neurons GO:0007272 76 0.042
divalent metal ion transport GO:0070838 172 0.041
regulation of response to reactive oxygen species GO:1901031 9 0.040
granulocyte migration GO:0097530 43 0.040
response to alcohol GO:0097305 48 0.039
regulation of protein localization GO:0032880 231 0.039
cell type specific apoptotic process GO:0097285 268 0.039
response to thyroid hormone GO:0097066 2 0.039
cerebellar granular layer development GO:0021681 13 0.039
positive regulation of nervous system development GO:0051962 221 0.039
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.038
organic acid catabolic process GO:0016054 51 0.038
regulation of defense response GO:0031347 233 0.038
regulation of response to wounding GO:1903034 189 0.038
necrotic cell death GO:0070265 30 0.037
Worm
locomotory behavior GO:0007626 195 0.037
cellular ion homeostasis GO:0006873 165 0.037
response to reactive oxygen species GO:0000302 56 0.037
sphingosine metabolic process GO:0006670 4 0.036
reactive oxygen species metabolic process GO:0072593 84 0.036
neuromuscular process controlling balance GO:0050885 59 0.036
defense response to gram positive bacterium GO:0050830 50 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.036
cellular glucan metabolic process GO:0006073 32 0.035
liposaccharide metabolic process GO:1903509 27 0.035
gene silencing by rna GO:0031047 19 0.035
transmission of nerve impulse GO:0019226 76 0.035
protein autoprocessing GO:0016540 2 0.034
positive regulation of secretion GO:0051047 130 0.034
rho protein signal transduction GO:0007266 32 0.034
polysaccharide metabolic process GO:0005976 39 0.034
central nervous system neuron differentiation GO:0021953 162 0.034
response to extracellular stimulus GO:0009991 127 0.033
small gtpase mediated signal transduction GO:0007264 97 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.033
organonitrogen compound catabolic process GO:1901565 264 0.032
transmembrane transport GO:0055085 412 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
ceramide catabolic process GO:0046514 7 0.032
multicellular organismal signaling GO:0035637 91 0.031
neuron projection extension GO:1990138 64 0.031
urogenital system development GO:0001655 261 0.031
Mouse
regulation of binding GO:0051098 111 0.031
cation transmembrane transport GO:0098655 266 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.030
sequestering of calcium ion GO:0051208 18 0.030
monocarboxylic acid catabolic process GO:0072329 27 0.030
regulation of membrane potential GO:0042391 192 0.030
regulation of homeostatic process GO:0032844 182 0.030
negative regulation of neuron apoptotic process GO:0043524 92 0.030
morphogenesis of a branching epithelium GO:0061138 193 0.030
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.030
developmental growth involved in morphogenesis GO:0060560 138 0.030
glycerolipid catabolic process GO:0046503 16 0.030
organelle fission GO:0048285 170 0.029
action potential GO:0001508 78 0.029
female gamete generation GO:0007292 74 0.029
skeletal system development GO:0001501 356 0.029
germ cell development GO:0007281 185 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
carbohydrate metabolic process GO:0005975 230 0.029
neuron apoptotic process GO:0051402 142 0.028
regulated secretory pathway GO:0045055 32 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
lipid localization GO:0010876 126 0.027
cell adhesion GO:0007155 329 0.027
cellular ketone metabolic process GO:0042180 84 0.027
carbohydrate homeostasis GO:0033500 128 0.027
positive regulation of peptide secretion GO:0002793 33 0.026
natural killer cell mediated immunity GO:0002228 29 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
triglyceride metabolic process GO:0006641 51 0.026
cell activation involved in immune response GO:0002263 126 0.026
cell chemotaxis GO:0060326 81 0.026
regulation of cellular response to stress GO:0080135 159 0.026
regulation of calcium ion transport GO:0051924 69 0.026
positive regulation of response to wounding GO:1903036 66 0.025
negative regulation of molecular function GO:0044092 258 0.025
rna interference GO:0016246 2 0.025
camera type eye development GO:0043010 266 0.025
receptor mediated endocytosis GO:0006898 51 0.025
organelle localization GO:0051640 179 0.025
sulfur compound metabolic process GO:0006790 100 0.025
lateral line system development GO:0048925 1 0.025
regulation of necrotic cell death GO:0010939 13 0.025
cellular amine metabolic process GO:0044106 44 0.024
cellular modified amino acid metabolic process GO:0006575 63 0.024
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.024
lymphocyte activation involved in immune response GO:0002285 93 0.024
inorganic ion transmembrane transport GO:0098660 234 0.024
establishment of organelle localization GO:0051656 122 0.024
ruffle organization GO:0031529 16 0.023
positive regulation of mapk cascade GO:0043410 170 0.023
skin development GO:0043588 220 0.023
negative regulation of cellular response to oxidative stress GO:1900408 10 0.023
hormone secretion GO:0046879 128 0.023
regulation of calcium ion transport into cytosol GO:0010522 31 0.023
determination of left right symmetry GO:0007368 80 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
organophosphate catabolic process GO:0046434 232 0.022
muscle contraction GO:0006936 101 0.022
negative regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000584 2 0.022
acetylcholine transport GO:0015870 2 0.022
regulation of leukocyte mediated immunity GO:0002703 104 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.021
glucose homeostasis GO:0042593 128 0.021
response to calcium ion GO:0051592 20 0.021
cell recognition GO:0008037 83 0.021
reproductive behavior GO:0019098 32 0.021
glycoprotein metabolic process GO:0009100 116 0.021
positive regulation of cellular component biogenesis GO:0044089 94 0.021
generation of precursor metabolites and energy GO:0006091 103 0.021
positive regulation of lipid metabolic process GO:0045834 40 0.021
nucleotide metabolic process GO:0009117 332 0.021
glycogen metabolic process GO:0005977 32 0.021
striated muscle cell development GO:0055002 125 0.021
sphingolipid catabolic process GO:0030149 7 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
positive regulation of innate immune response GO:0045089 80 0.020
anatomical structure homeostasis GO:0060249 145 0.020
regulation of kinase activity GO:0043549 249 0.020
t cell activation GO:0042110 289 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
ameboidal type cell migration GO:0001667 128 0.020
regulation of cytoplasmic transport GO:1903649 112 0.020
lipid transport GO:0006869 98 0.020
regulation of protein stability GO:0031647 52 0.020
organic anion transport GO:0015711 137 0.020
regulation of angiogenesis GO:0045765 81 0.020
actin cytoskeleton organization GO:0030036 220 0.019
aromatic compound catabolic process GO:0019439 286 0.019
maintenance of apical basal cell polarity GO:0035090 3 0.019
cellular response to acid chemical GO:0071229 68 0.019
positive regulation of cell development GO:0010720 237 0.019
epithelial cell development GO:0002064 159 0.019
negative regulation of transferase activity GO:0051348 85 0.019
gland development GO:0048732 330 0.019
male sex differentiation GO:0046661 109 0.019
Mouse
positive regulation of protein modification process GO:0031401 299 0.019
leukocyte chemotaxis GO:0030595 69 0.019
renal system development GO:0072001 225 0.019
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.019
cellular response to glucose stimulus GO:0071333 45 0.019
development of primary sexual characteristics GO:0045137 143 0.019
Mouse
regulation of microtubule based movement GO:0060632 8 0.018
peptide transport GO:0015833 133 0.018
ear development GO:0043583 200 0.018
monosaccharide metabolic process GO:0005996 106 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
maintenance of location in cell GO:0051651 24 0.018
negative regulation of protein maturation GO:1903318 79 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
lung morphogenesis GO:0060425 50 0.018
regulation of cellular response to oxidative stress GO:1900407 19 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
chemotaxis GO:0006935 247 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
regulation of neuron death GO:1901214 134 0.018
regulation of microtubule based process GO:0032886 52 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
regulation of cell cycle process GO:0010564 160 0.017
sterol homeostasis GO:0055092 45 0.017
axon ensheathment GO:0008366 76 0.017
negative regulation of organelle organization GO:0010639 90 0.017
adult locomotory behavior GO:0008344 91 0.017
leukocyte migration GO:0050900 124 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
natural killer cell mediated cytotoxicity GO:0042267 29 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
glucan metabolic process GO:0044042 32 0.017
positive regulation of immune effector process GO:0002699 107 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.017
sensory organ morphogenesis GO:0090596 242 0.017
release of sequestered calcium ion into cytosol GO:0051209 42 0.017
regulation of peptide transport GO:0090087 91 0.017
peripheral nervous system development GO:0007422 53 0.017
positive regulation of defense response GO:0031349 124 0.017
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.017
regulation of ion transmembrane transport GO:0034765 119 0.016
negative regulation of vesicle fusion GO:0031339 1 0.016
oligosaccharide metabolic process GO:0009311 11 0.016
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.016
amine metabolic process GO:0009308 45 0.016
regulation of cell activation GO:0050865 289 0.016
cellular polysaccharide metabolic process GO:0044264 38 0.016
positive regulation of hormone secretion GO:0046887 38 0.016
organelle membrane fusion GO:0090174 1 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
energy reserve metabolic process GO:0006112 39 0.016
regulation of regulated secretory pathway GO:1903305 20 0.016
response to metal ion GO:0010038 47 0.016
sphingoid metabolic process GO:0046519 5 0.016
negative regulation of protein processing GO:0010955 79 0.016
mapk cascade GO:0000165 281 0.016
regulation of protein transport GO:0051223 163 0.016
defense response to other organism GO:0098542 197 0.016
positive regulation of wnt signaling pathway GO:0030177 45 0.016
fat cell differentiation GO:0045444 160 0.016
circadian sleep wake cycle rem sleep GO:0042747 1 0.016
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.016
cerebellar cortex formation GO:0021697 22 0.016
endothelial cell migration GO:0043542 44 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
notochord cell development GO:0060035 1 0.015
meiotic nuclear division GO:0007126 115 0.015
cytoplasmic transport GO:0016482 234 0.015
cerebellum morphogenesis GO:0021587 42 0.015
forebrain generation of neurons GO:0021872 63 0.015
heterocycle catabolic process GO:0046700 280 0.015
multi organism reproductive behavior GO:0044705 29 0.015
cell substrate adhesion GO:0031589 130 0.015
cell killing GO:0001906 67 0.015
negative regulation of hydrolase activity GO:0051346 71 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
visual behavior GO:0007632 45 0.015
myosin filament organization GO:0031033 3 0.015
positive regulation of insulin secretion GO:0032024 26 0.015
natural killer cell activation GO:0030101 44 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.015
response to steroid hormone GO:0048545 56 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
regulation of intracellular transport GO:0032386 159 0.015
iron ion homeostasis GO:0055072 36 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.015
fertilization GO:0009566 127 0.014
regulation of vacuole organization GO:0044088 4 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
sensory perception GO:0007600 245 0.014
l ascorbic acid metabolic process GO:0019852 4 0.014
meiotic cell cycle GO:0051321 122 0.014
lysosomal transport GO:0007041 10 0.014
cholesterol homeostasis GO:0042632 44 0.014
activation of adenylate cyclase activity GO:0007190 4 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
fibrinolysis GO:0042730 3 0.014
hydrogen transport GO:0006818 35 0.014
organic acid transport GO:0015849 101 0.014
single fertilization GO:0007338 82 0.014
forebrain radial glial cell differentiation GO:0021861 4 0.014
respiratory system development GO:0060541 190 0.014
gonad development GO:0008406 141 0.014
Mouse
male gonad development GO:0008584 88 0.014
Mouse
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.014
neutral lipid metabolic process GO:0006638 57 0.014
cellular protein complex assembly GO:0043623 116 0.014
actin filament polymerization GO:0030041 44 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
immune effector process GO:0002252 321 0.013
regulation of peptide secretion GO:0002791 77 0.013
myeloid leukocyte migration GO:0097529 57 0.013
epithelium migration GO:0090132 63 0.013
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.013
extracellular matrix organization GO:0030198 147 0.013
glycosphingolipid metabolic process GO:0006687 18 0.013
positive regulation of behavior GO:0048520 40 0.013
cytokine production GO:0001816 319 0.013
substrate adhesion dependent cell spreading GO:0034446 30 0.013
phospholipid metabolic process GO:0006644 87 0.013
striated muscle myosin thick filament assembly GO:0071688 1 0.013
regulation of body fluid levels GO:0050878 162 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of anatomical structure size GO:0090066 178 0.013
insulin secretion GO:0030073 89 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
intracellular protein transport GO:0006886 204 0.013
positive regulation of exocytosis GO:0045921 20 0.013
lipid homeostasis GO:0055088 63 0.013
single organism cell adhesion GO:0098602 156 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
negative regulation of oxidative stress induced cell death GO:1903202 9 0.013
actin filament branching GO:0090135 1 0.013
amide transport GO:0042886 138 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.012
positive regulation of cell motility GO:2000147 116 0.012
tissue migration GO:0090130 68 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
nuclear import GO:0051170 95 0.012
neural precursor cell proliferation GO:0061351 121 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
formation of primary germ layer GO:0001704 77 0.012
retina development in camera type eye GO:0060041 119 0.012
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.012
calcium ion transport into cytosol GO:0060402 48 0.012
regulation of cytokine production GO:0001817 266 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
regulation of hormone secretion GO:0046883 88 0.012
negative regulation of response to wounding GO:1903035 77 0.012
response to hydrogen peroxide GO:0042542 32 0.012
negative regulation of protein localization to nucleus GO:1900181 23 0.012
exocrine system development GO:0035272 45 0.012
cellular alcohol metabolic process GO:0044107 3 0.012
negative regulation of peptidase activity GO:0010466 46 0.012
negative regulation of map kinase activity GO:0043407 34 0.012
regulation of immunological synapse formation GO:2000520 2 0.012
positive regulation of sequestering of triglyceride GO:0010890 4 0.012
oogenesis GO:0048477 56 0.012
defense response to bacterium GO:0042742 119 0.012
meiotic cell cycle process GO:1903046 77 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.012
actin filament organization GO:0007015 113 0.012
blastocyst development GO:0001824 80 0.012
regulation of cell projection organization GO:0031344 206 0.012
nitrogen compound transport GO:0071705 271 0.012
maintenance of presynaptic active zone structure GO:0048790 1 0.012
response to starvation GO:0042594 65 0.011
negative regulation of response to oxidative stress GO:1902883 10 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of transferase activity GO:0051338 263 0.011
regulation of natural killer cell mediated immunity GO:0002715 19 0.011
astrocyte cell migration GO:0043615 3 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
protein oligomerization GO:0051259 67 0.011
regulation of exocytosis GO:0017157 61 0.011
muscle system process GO:0003012 141 0.011
positive regulation of cell migration GO:0030335 109 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of transmembrane transport GO:0034762 128 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
membrane lipid biosynthetic process GO:0046467 32 0.011
negative regulation of intracellular transport GO:0032387 38 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
acetylcholine secretion neurotransmission GO:0014055 2 0.011
positive regulation of cell activation GO:0050867 158 0.011
regulation of chemotaxis GO:0050920 53 0.011
neutrophil chemotaxis GO:0030593 36 0.011
lung development GO:0030324 164 0.011
response to nutrient levels GO:0031667 109 0.011
positive regulation of lamellipodium organization GO:1902745 3 0.011
positive regulation of ion transport GO:0043270 65 0.011
respiratory tube development GO:0030323 167 0.011
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.011
neuron death GO:0070997 154 0.011

Ctsd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.950
Human
inherited metabolic disorder DOID:655 0 0.950
Human
lipid storage disease DOID:9455 0 0.820
Human
lysosomal storage disease DOID:3211 0 0.820
Human
sphingolipidosis DOID:1927 0 0.820
central nervous system disease DOID:331 0 0.425
disease of anatomical entity DOID:7 0 0.425
nervous system disease DOID:863 0 0.425
cerebral degeneration DOID:1443 0 0.389
brain disease DOID:936 0 0.389
immune system disease DOID:2914 0 0.104
lymphatic system disease DOID:75 0 0.104
neurodegenerative disease DOID:1289 0 0.041
dementia DOID:1307 0 0.032
disease of mental health DOID:150 0 0.032
cognitive disorder DOID:1561 0 0.032
alzheimer s disease DOID:10652 0 0.027
tauopathy DOID:680 0 0.027
neuronal ceroid lipofuscinosis DOID:14503 0 0.014
Human
epilepsy syndrome DOID:1826 0 0.012
electroclinical syndrome DOID:0050701 0 0.012
variable age at onset electroclinical syndrome DOID:0050706 0 0.012
progressive myoclonus epilepsy DOID:891 0 0.012
retinal disease DOID:5679 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.011