|
|
immune effector process
|
GO:0002252 |
321 |
0.791
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.716
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.714
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.704
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.649
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.635
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.602
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.593
|
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.582
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.577
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.570
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.570
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.549
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.491
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.483
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.482
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.472
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.469
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.465
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.462
|
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.454
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.454
|
|
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.453
|
|
|
|
cellular response to interferon beta
|
GO:0035458 |
21 |
0.451
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.448
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.430
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.426
|
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.426
|
|
|
|
regulation of dendritic cell dendrite assembly
|
GO:2000547 |
2 |
0.420
|
|
|
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.412
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.394
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.373
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.347
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.345
|
Mouse |
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.337
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.331
|
Mouse |
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.323
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.318
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.316
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.301
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.297
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.276
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.274
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.273
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.272
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.270
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.261
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.258
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.256
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.251
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.250
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.248
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.247
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.245
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.243
|
|
|
|
natural killer cell chemotaxis
|
GO:0035747 |
1 |
0.240
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.240
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.236
|
|
|
|
regulation of immunoglobulin production in mucosal tissue
|
GO:2000557 |
1 |
0.235
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.224
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.218
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.216
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.215
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.213
|
|
|
|
immunoglobulin production in mucosal tissue
|
GO:0002426 |
3 |
0.213
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.212
|
|
|
|
b cell chemotaxis
|
GO:0035754 |
3 |
0.210
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.210
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.207
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.207
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.204
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.200
|
|
|
|
dendritic cell dendrite assembly
|
GO:0097026 |
2 |
0.198
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.194
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.191
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.191
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.186
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.184
|
|
|
|
positive regulation of t helper 1 cell cytokine production
|
GO:2000556 |
1 |
0.183
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.183
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.182
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.180
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.178
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.172
|
Mouse |
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.172
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.171
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.170
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.168
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.167
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.166
|
Human |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.166
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.164
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.163
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.161
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.160
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.157
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.157
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.153
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.151
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.150
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.150
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.149
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.149
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.149
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.148
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.148
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.147
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.146
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.143
|
Human |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.140
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.139
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.139
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.138
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.138
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.138
|
|
|
|
regulation of natural killer cell chemotaxis
|
GO:2000501 |
1 |
0.138
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.137
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.134
|
Human |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.134
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.134
|
|
|
|
regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000561 |
2 |
0.132
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.131
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.130
|
|
|
|
regulation of b cell chemotaxis
|
GO:2000537 |
2 |
0.130
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.130
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.129
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.126
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.126
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.125
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.125
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.124
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.122
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.121
|
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.118
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.118
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.117
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.117
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.115
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.115
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.115
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.115
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.114
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.114
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.114
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
7 |
0.112
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.111
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.111
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.111
|
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.110
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.108
|
Mouse |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.108
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.108
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.107
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.105
|
Human |
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.105
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.104
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.103
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.103
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.103
|
Human |
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.103
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.102
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.101
|
Human Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.101
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.100
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.099
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.099
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.098
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.098
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.098
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.098
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.097
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.097
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.096
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.095
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.094
|
Human |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.094
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.093
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.092
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.091
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.089
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.089
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.088
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.088
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.088
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.087
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.086
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.085
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.085
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.084
|
Mouse |
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.084
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.083
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.083
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.082
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.080
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.080
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.079
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.078
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.077
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.077
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.077
|
|
|
|
positive regulation of b cell chemotaxis
|
GO:2000538 |
2 |
0.077
|
|
|
|
granzyme mediated apoptotic signaling pathway
|
GO:0008626 |
1 |
0.075
|
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.075
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.075
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.074
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.074
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.074
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.073
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.073
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.072
|
Human |
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.071
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.070
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.070
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.070
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.069
|
Human |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.068
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.068
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.068
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.068
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.068
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.067
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.067
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.066
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.065
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.065
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.064
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.064
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.064
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.063
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.063
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.063
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.063
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.063
|
Human Mouse |
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.062
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.062
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.062
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.061
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
6 |
0.061
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.061
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.060
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.060
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
28 |
0.060
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.060
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.060
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.060
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.059
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.059
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.059
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.059
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.059
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.059
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.058
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.058
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.058
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.058
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.058
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.057
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.057
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.057
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.057
|
Human |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.057
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.056
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.056
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.056
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.056
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.056
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.056
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.056
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.055
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.055
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.054
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.054
|
Human |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.053
|
Mouse |
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.053
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.053
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.053
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.053
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.052
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.052
|
|
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
10 |
0.052
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.052
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.052
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.051
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.051
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.051
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.050
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.050
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.050
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.050
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.050
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.050
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.050
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.049
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.049
|
Mouse |
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.049
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.049
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.049
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.048
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.048
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.048
|
Mouse |
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.048
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.048
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.047
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.047
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.046
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
7 |
0.046
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.045
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.045
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.045
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.045
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.045
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.045
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.044
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.044
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.044
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.044
|
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.044
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.044
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.044
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.044
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.044
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.043
|
|
|
|
regulation of adiponectin secretion
|
GO:0070163 |
2 |
0.043
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.043
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.043
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.043
|
Human |
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.043
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.043
|
|
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.043
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.042
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.042
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.042
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.042
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.042
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.042
|
Mouse |
|
|
lymphocyte chemotaxis
|
GO:0048247 |
10 |
0.042
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.042
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.041
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.041
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.041
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.041
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.041
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.041
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.040
|
Mouse |
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
18 |
0.040
|
Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.040
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.040
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.040
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.039
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.039
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.039
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.039
|
Human |
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.039
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.039
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.038
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.038
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.038
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.038
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.037
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.037
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.037
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.037
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.037
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.037
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.037
|
Human |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.037
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.037
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.037
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.037
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.036
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.036
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.036
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.036
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.036
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.036
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.036
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.036
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.035
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.035
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.035
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.035
|
|
|
|
regulation of angiotensin metabolic process
|
GO:0060177 |
4 |
0.035
|
|
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.035
|
|
|
|
macrophage migration inhibitory factor signaling pathway
|
GO:0035691 |
2 |
0.035
|
|
|
|
cellular response to interferon alpha
|
GO:0035457 |
4 |
0.035
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.035
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.034
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.034
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.034
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.033
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.033
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.033
|
Human |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.033
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.033
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.033
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.033
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.033
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.033
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.033
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.033
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.032
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.032
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.032
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.032
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.032
|
Human |
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.032
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.032
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.031
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.031
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.031
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.031
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.031
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.030
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.030
|
Mouse |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.030
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.030
|
|
|
|
monocyte chemotaxis
|
GO:0002548 |
5 |
0.030
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.030
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.030
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.030
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.030
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.030
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.030
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.030
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.030
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.029
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.029
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.029
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.029
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.029
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.029
|
Human |
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.029
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.029
|
|
|
|
response to interferon beta
|
GO:0035456 |
22 |
0.029
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.029
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.029
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.029
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.029
|
Human |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.029
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.029
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.029
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.029
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.029
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.028
|
|
|
|
negative regulation of gluconeogenesis
|
GO:0045721 |
9 |
0.028
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.028
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.028
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.028
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.028
|
Mouse |
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.028
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.028
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.028
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.028
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.027
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.027
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.027
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.027
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.027
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.027
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.027
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.027
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.027
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.027
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.027
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.027
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.027
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.027
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.027
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.027
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.026
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.026
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.026
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.026
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.026
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.026
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.025
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.025
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.025
|
Human |
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.025
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.025
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.025
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
19 |
0.025
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.025
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
10 |
0.025
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.025
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.025
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.024
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
14 |
0.024
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.024
|
|
|
|
regulation of cholesterol metabolic process
|
GO:0090181 |
14 |
0.024
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.024
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.024
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.024
|
Human |
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.024
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.024
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.024
|
Human |
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.024
|
Mouse |
