|
|
response to radiation
|
GO:0009314 |
165 |
0.947
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.941
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.901
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.899
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.894
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.893
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.880
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.859
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.854
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.852
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.847
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.829
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.825
|
Human |
|
|
autophagy
|
GO:0006914 |
45 |
0.814
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.810
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.806
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.805
|
Human |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.798
|
Human |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.794
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.784
|
Fly |
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.767
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.759
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.733
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
21 |
0.719
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.718
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.708
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.707
|
Human |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.698
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.693
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.687
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.670
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.666
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.663
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.654
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.653
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.645
|
Human |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.635
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.623
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.619
|
Fly |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.618
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.612
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.611
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.607
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.603
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.601
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.598
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.596
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.594
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.590
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.589
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.585
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.584
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.583
|
Human |
|
|
coenzyme biosynthetic process
|
GO:0009108 |
23 |
0.579
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.572
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.572
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.570
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.569
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.556
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.554
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.553
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.553
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.548
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.546
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.540
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.538
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.531
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.522
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.517
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.510
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.507
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.507
|
Human |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.504
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.503
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.502
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.500
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.496
|
Human |
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.493
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.485
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.484
|
Human |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.477
|
|
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
3 |
0.475
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.468
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.468
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.467
|
|
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.464
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.456
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.455
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.452
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.445
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.438
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.434
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.433
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.429
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.428
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.426
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.425
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.424
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.424
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.422
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.414
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.412
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.410
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.407
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.405
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.405
|
Fly |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.405
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.401
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.401
|
|
|
|
regulation of nitrogen utilization
|
GO:0006808 |
2 |
0.398
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.396
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.392
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.392
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.390
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.385
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.380
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.380
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.379
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.376
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.374
|
|
|
|
cellular alcohol biosynthetic process
|
GO:0044108 |
3 |
0.372
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.369
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.367
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.366
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.364
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.359
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.357
|
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.355
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.355
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.353
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.350
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.348
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.344
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.344
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.343
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.341
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.341
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.334
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.333
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.331
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.329
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.329
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.326
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.325
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.323
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.322
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.320
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.317
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.315
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.311
|
|
|
|
negative regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030948 |
6 |
0.311
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.310
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.308
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.308
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.307
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.307
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.305
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.304
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.300
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.298
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.297
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.296
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.296
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.295
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.292
|
|
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
14 |
0.291
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.290
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
1 |
0.290
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.290
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.289
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.288
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.286
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.284
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.284
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.284
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.278
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.277
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.276
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.276
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.276
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.272
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.271
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.269
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.268
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.268
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.265
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.263
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.262
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.261
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.260
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.260
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.257
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.256
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.255
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.254
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.254
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.254
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.248
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.248
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.246
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.243
|
Human |
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.240
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.240
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.236
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.236
|
Human |
|
|
b cell activation
|
GO:0042113 |
161 |
0.235
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.235
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.235
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.234
|
Human |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.234
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.232
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.232
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.229
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.229
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.228
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.226
|
Human |
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.226
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.225
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.223
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.222
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.221
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.220
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.219
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.217
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.216
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.215
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.214
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.213
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.212
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.211
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.209
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.208
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.208
|
Human |
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.208
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
15 |
0.208
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.206
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.206
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.203
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.202
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.201
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.201
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.201
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.200
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.200
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.197
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.195
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.194
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.191
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.189
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.189
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
10 |
0.187
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.187
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.185
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.184
|
Human |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.183
|
|
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
13 |
0.183
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.183
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.181
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.181
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.178
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.178
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.177
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.177
|
|
|
|
cellular alcohol metabolic process
|
GO:0044107 |
3 |
0.177
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.176
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.175
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.175
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.175
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.175
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.174
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.172
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.172
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.171
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.171
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.170
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.170
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.169
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.169
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.169
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.167
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.167
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.167
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.166
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.163
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.162
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
2 |
0.162
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.160
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.160
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.159
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.159
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.158
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.156
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.156
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.156
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.155
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.154
|
Human |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.153
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.152
|
Human |
|
|
macroautophagy
|
GO:0016236 |
21 |
0.152
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.151
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.150
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.150
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.150
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.149
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.149
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.148
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.147
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.146
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.145
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.145
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.145
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.144
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.143
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.142
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.142
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.140
|
|
|
|
isoprenoid biosynthetic process
|
GO:0008299 |
9 |
0.140
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.140
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.140
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.140
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.139
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.138
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.138
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.138
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.138
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.137
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.137
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.137
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.137
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.137
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.137
|
|
|
|
quinone biosynthetic process
|
GO:1901663 |
4 |
0.136
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.136
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.135
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.135
|
Human |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.134
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.134
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.133
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.133
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.132
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.130
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.130
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.129
|
Human |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.128
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.128
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.126
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.126
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.126
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.126
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.125
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.125
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.123
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.122
|
|
|
|
regulation of rna export from nucleus
|
GO:0046831 |
4 |
0.121
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.121
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.120
|
|
|
|
regulation of dna binding
|
GO:0051101 |
39 |
0.120
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.120
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.119
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.119
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.118
|
Human |
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.118
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.116
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.116
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.116
|
|
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.115
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.114
|
|
|
|
translation
|
GO:0006412 |
93 |
0.113
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.113
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.113
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.113
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.112
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.112
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.112
|
|
|
|
trna processing
|
GO:0008033 |
11 |
0.111
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
1 |
0.111
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.110
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.110
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.109
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.109
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.109
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.109
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.107
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.107
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.107
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.106
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.106
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.106
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.106
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.105
|
|
|
|
axonal fasciculation
|
GO:0007413 |
15 |
0.105
|
|
|
|
ubiquinone metabolic process
|
GO:0006743 |
4 |
0.105
|
|
|
|
cofactor biosynthetic process
|
GO:0051188 |
41 |
0.104
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.104
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.103
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.102
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.102
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.102
|
Human |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.102
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.101
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.101
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.101
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.100
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.100
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.099
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.099
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.099
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.099
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.098
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.098
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.098
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.098
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.097
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.097
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.097
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.097
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.096
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.096
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.096
|
Human |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.095
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.095
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.095
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.094
|
Human |
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.094
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.094
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.094
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.093
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.093
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.093
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.092
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.092
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.091
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.091
|
Human |
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
5 |
0.091
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.091
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.091
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.091
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.090
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.090
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.090
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.090
|
Human |
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.089
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.089
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.089
|
Human |
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.089
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.088
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.088
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.087
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.087
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.084
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.084
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
25 |
0.084
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.083
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.083
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.083
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.082
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.082
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.082
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.082
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.082
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.082
|
Human |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.081
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.081
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.080
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.080
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.080
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.080
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.080
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.079
|
|
|
|
regulation of coenzyme metabolic process
|
GO:0051196 |
4 |
0.079
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.079
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.079
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.079
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.078
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.078
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.078
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.078
|
Human |
|
|
germ cell development
|
GO:0007281 |
185 |
0.078
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.077
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.077
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.077
|
Human |
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.077
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.077
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
52 |
0.077
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.077
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.076
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.076
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.076
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
80 |
0.076
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.075
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.075
|
|
|
|
cellular response to misfolded protein
|
GO:0071218 |
5 |
0.075
|
|
