Mus musculus

18 known processes

Cyp17a1

cytochrome P450, family 17, subfamily a, polypeptide 1

(Aliases: Cyp17,p450c17)

Cyp17a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.499
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.258
Mouse
steroid metabolic process GO:0008202 119 0.204
lipid biosynthetic process GO:0008610 179 0.198
cellular amino acid metabolic process GO:0006520 103 0.184
negative regulation of endothelial cell migration GO:0010596 4 0.166
protein processing GO:0016485 163 0.124
sterol metabolic process GO:0016125 58 0.102
lipid catabolic process GO:0016042 69 0.098
Mouse
fat soluble vitamin biosynthetic process GO:0042362 4 0.095
amine metabolic process GO:0009308 45 0.092
Mouse
cellular amine metabolic process GO:0044106 44 0.082
small molecule biosynthetic process GO:0044283 132 0.079
regulation of cellular ketone metabolic process GO:0010565 66 0.075
protein maturation GO:0051604 176 0.069
organic hydroxy compound biosynthetic process GO:1901617 77 0.068
sperm motility GO:0030317 47 0.068
hormone metabolic process GO:0042445 86 0.066
Human Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.064
triglyceride metabolic process GO:0006641 51 0.062
organic cyclic compound catabolic process GO:1901361 295 0.060
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
alcohol metabolic process GO:0006066 116 0.053
Mouse
cofactor metabolic process GO:0051186 80 0.052
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.051
cholesterol homeostasis GO:0042632 44 0.049
regulation of secretion GO:0051046 274 0.049
regulation of hormone levels GO:0010817 211 0.048
Human Mouse Rat
multicellular organism growth GO:0035264 161 0.048
spermatogenesis GO:0007283 284 0.047
fatty acid metabolic process GO:0006631 121 0.047
Mouse
positive regulation of secretion GO:0051047 130 0.046
nucleotide metabolic process GO:0009117 332 0.044
oxidation reduction process GO:0055114 342 0.041
regulation of transferase activity GO:0051338 263 0.041
germ cell development GO:0007281 185 0.040
macromolecule catabolic process GO:0009057 281 0.039
apoptotic signaling pathway GO:0097190 306 0.039
Mouse
acylglycerol metabolic process GO:0006639 55 0.039
endocrine process GO:0050886 39 0.039
regulation of proteolysis GO:0030162 164 0.039
lipid localization GO:0010876 126 0.038
vitamin d biosynthetic process GO:0042368 3 0.038
organic anion transport GO:0015711 137 0.037
tissue migration GO:0090130 68 0.037
Mouse
muscle cell differentiation GO:0042692 261 0.036
response to metal ion GO:0010038 47 0.036
Mouse
development of primary female sexual characteristics GO:0046545 73 0.035
wound healing GO:0042060 157 0.035
alcohol biosynthetic process GO:0046165 43 0.035
negative regulation of protein processing GO:0010955 79 0.035
lipid homeostasis GO:0055088 63 0.034
cytokine production GO:0001816 319 0.034
Mouse
dibenzo p dioxin metabolic process GO:0018894 1 0.033
Mouse Rat
fertilization GO:0009566 127 0.032
organic acid biosynthetic process GO:0016053 86 0.032
cellular homeostasis GO:0019725 240 0.032
cellular response to hormone stimulus GO:0032870 150 0.032
Rat
defense response to bacterium GO:0042742 119 0.031
regulation of endocytosis GO:0030100 69 0.031
response to extracellular stimulus GO:0009991 127 0.031
Rat
hemostasis GO:0007599 78 0.031
negative regulation of molecular function GO:0044092 258 0.031
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.031
terpenoid metabolic process GO:0006721 25 0.030
Mouse
vitamin metabolic process GO:0006766 23 0.030
anion transport GO:0006820 177 0.030
carboxylic acid biosynthetic process GO:0046394 86 0.029
leukocyte differentiation GO:0002521 342 0.029
response to inorganic substance GO:0010035 96 0.029
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.028
Mouse Rat
actin cytoskeleton organization GO:0030036 220 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
epithelium migration GO:0090132 63 0.028
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
multi multicellular organism process GO:0044706 109 0.028
myosin filament organization GO:0031033 3 0.028
regulation of protein maturation GO:1903317 96 0.028
retinoid metabolic process GO:0001523 24 0.027
Mouse
glycerolipid metabolic process GO:0046486 122 0.027
defense response to other organism GO:0098542 197 0.027
regulation of secretion by cell GO:1903530 249 0.026
cellular response to extracellular stimulus GO:0031668 81 0.026
regulation of systemic arterial blood pressure GO:0003073 61 0.026
negative regulation of proteolysis GO:0045861 74 0.026
purine containing compound metabolic process GO:0072521 311 0.026
innate immune response GO:0045087 157 0.026
spermatid differentiation GO:0048515 115 0.026
regulation of microvillus organization GO:0032530 3 0.026
regulation of protein processing GO:0070613 96 0.026
cellular response to inorganic substance GO:0071241 37 0.025
Mouse
small molecule catabolic process GO:0044282 71 0.025
regulation of hydrolase activity GO:0051336 246 0.025
androgen biosynthetic process GO:0006702 4 0.025
regulation of lymphocyte activation GO:0051249 240 0.025
sulfur compound metabolic process GO:0006790 100 0.025
lipid transport GO:0006869 98 0.025
regulation of protein localization GO:0032880 231 0.025
cellular response to gonadotropin stimulus GO:0071371 4 0.025
Rat
establishment of blood nerve barrier GO:0008065 3 0.025
negative regulation of growth GO:0045926 99 0.025
regulation of lipid metabolic process GO:0019216 118 0.025
Rat
protein catabolic process GO:0030163 221 0.024
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.024
positive regulation of lipid metabolic process GO:0045834 40 0.024
Rat
dna metabolic process GO:0006259 303 0.024
regulation of defense response GO:0031347 233 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
response to radiation GO:0009314 165 0.024
Rat
cellular chemical homeostasis GO:0055082 215 0.023
response to acid chemical GO:0001101 111 0.023
Rat
positive regulation of transferase activity GO:0051347 167 0.023
alpha amino acid metabolic process GO:1901605 59 0.023
cellular alcohol metabolic process GO:0044107 3 0.023
negative regulation of protein maturation GO:1903318 79 0.022
aromatic compound catabolic process GO:0019439 286 0.022
digestive system development GO:0055123 200 0.022
regulation of peptidase activity GO:0052547 96 0.022
acute inflammatory response GO:0002526 41 0.022
regulation of endopeptidase activity GO:0052548 89 0.022
cellular amide metabolic process GO:0043603 58 0.022
circulatory system process GO:0003013 197 0.022
urogenital system development GO:0001655 261 0.022
vascular process in circulatory system GO:0003018 62 0.022
neutral lipid metabolic process GO:0006638 57 0.022
isoprenoid metabolic process GO:0006720 29 0.022
Mouse
renal system development GO:0072001 225 0.021
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
metal ion homeostasis GO:0055065 189 0.021
myeloid cell differentiation GO:0030099 233 0.021
regulation of blood pressure GO:0008217 93 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
regulation of microvillus assembly GO:0032534 3 0.021
male gamete generation GO:0048232 285 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
testosterone biosynthetic process GO:0061370 2 0.021
drug catabolic process GO:0042737 2 0.021
striated muscle myosin thick filament assembly GO:0071688 1 0.021
cellular ion homeostasis GO:0006873 165 0.020
fat soluble vitamin metabolic process GO:0006775 11 0.020
heterocycle catabolic process GO:0046700 280 0.020
regulation of blood vessel size GO:0050880 56 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
immune effector process GO:0002252 321 0.020
cell substrate adhesion GO:0031589 130 0.020
cofactor transport GO:0051181 4 0.020
cellular lipid catabolic process GO:0044242 52 0.020
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.020
regulation of t cell activation GO:0050863 170 0.020
secondary alcohol metabolic process GO:1902652 3 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
blood circulation GO:0008015 195 0.019
rho protein signal transduction GO:0007266 32 0.019
cellular alcohol biosynthetic process GO:0044108 3 0.019
peptidyl serine modification GO:0018209 83 0.019
regulation of kinase activity GO:0043549 249 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
negative regulation of endopeptidase activity GO:0010951 44 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.019
protein glycosylation GO:0006486 55 0.019
benzene containing compound metabolic process GO:0042537 5 0.018
Rat
negative regulation of cell proliferation GO:0008285 296 0.018
Mouse
carbohydrate metabolic process GO:0005975 230 0.018
regulation of angiotensin metabolic process GO:0060177 4 0.018
cell type specific apoptotic process GO:0097285 268 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
Mouse
female gamete generation GO:0007292 74 0.018
Rat
endothelial cell migration GO:0043542 44 0.018
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.018
regulation of protein secretion GO:0050708 82 0.018
monocarboxylic acid biosynthetic process GO:0072330 61 0.018
cholesterol metabolic process GO:0008203 56 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
monosaccharide metabolic process GO:0005996 106 0.018
inflammatory response GO:0006954 244 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.017
regulation of tube size GO:0035150 57 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
cellular ketone metabolic process GO:0042180 84 0.017
Human
negative regulation of protein metabolic process GO:0051248 282 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
activation of immune response GO:0002253 138 0.017
development of primary sexual characteristics GO:0045137 143 0.017
Rat
gland development GO:0048732 330 0.017
Rat
regulation of angiotensin levels in blood GO:0002002 4 0.017
peptide metabolic process GO:0006518 46 0.017
response to oxidative stress GO:0006979 123 0.017
Mouse
negative regulation of hydrolase activity GO:0051346 71 0.017
steroid biosynthetic process GO:0006694 47 0.017
regulation of renal sodium excretion GO:0035813 3 0.017
negative regulation of lymphocyte activation GO:0051250 91 0.017
regulation of innate immune response GO:0045088 91 0.016
regulation of protein transport GO:0051223 163 0.016
blood coagulation GO:0007596 76 0.016
response to steroid hormone GO:0048545 56 0.016
Rat
single fertilization GO:0007338 82 0.016
phospholipid metabolic process GO:0006644 87 0.016
humoral immune response GO:0006959 57 0.016
response to organic cyclic compound GO:0014070 198 0.016
Rat
positive regulation of kinase activity GO:0033674 155 0.016
leukocyte mediated immunity GO:0002443 174 0.016
regulation of response to wounding GO:1903034 189 0.016
endothelial cell differentiation GO:0045446 41 0.015
catecholamine uptake GO:0090493 4 0.015
negative regulation of peptidase activity GO:0010466 46 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
protein localization to organelle GO:0033365 185 0.015
positive regulation of cell death GO:0010942 224 0.015
Mouse
response to organonitrogen compound GO:0010243 246 0.015
Rat
negative regulation of cell activation GO:0050866 111 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
response to nutrient levels GO:0031667 109 0.015
Rat
maintenance of location GO:0051235 89 0.015
cellular aldehyde metabolic process GO:0006081 12 0.015
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
calcium ion homeostasis GO:0055074 127 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
blood vessel morphogenesis GO:0048514 285 0.015
Mouse
cellular response to peptide GO:1901653 92 0.015
positive regulation of protein modification process GO:0031401 299 0.015
positive regulation of growth GO:0045927 104 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.015
regulation of inflammatory response GO:0050727 147 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
cell maturation GO:0048469 127 0.014
renal tubule morphogenesis GO:0061333 72 0.014
diterpenoid metabolic process GO:0016101 24 0.014
Mouse
ribose phosphate metabolic process GO:0019693 291 0.014
telencephalon development GO:0021537 186 0.014
Rat
regulation of protein kinase activity GO:0045859 232 0.014
cellular response to external stimulus GO:0071496 88 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of ion transport GO:0043269 215 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
endothelium development GO:0003158 45 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
regulation of protein catabolic process GO:0042176 108 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
endocytosis GO:0006897 168 0.014
developmental maturation GO:0021700 193 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
oxygen homeostasis GO:0032364 2 0.014
cellular response to lipid GO:0071396 145 0.014
Rat
cellular response to cadmium ion GO:0071276 3 0.013
Mouse
regulation of ion homeostasis GO:2000021 64 0.013
regulation of anatomical structure size GO:0090066 178 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
mesonephric tubule morphogenesis GO:0072171 63 0.013
sterol homeostasis GO:0055092 45 0.013
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.013
organic acid transport GO:0015849 101 0.013
icosanoid metabolic process GO:0006690 33 0.013
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
positive regulation of protein secretion GO:0050714 52 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
nitrogen compound transport GO:0071705 271 0.013
regulation of hormone secretion GO:0046883 88 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
rna interference GO:0016246 2 0.013
regulation of carbohydrate metabolic process GO:0006109 75 0.013
peptidyl amino acid modification GO:0018193 336 0.013
regulation of peptide secretion GO:0002791 77 0.013
macromolecule methylation GO:0043414 120 0.013
exogenous drug catabolic process GO:0042738 1 0.013
vitamin d3 metabolic process GO:0070640 3 0.013
mesonephros development GO:0001823 97 0.013
organophosphate catabolic process GO:0046434 232 0.013
epithelial cell proliferation GO:0050673 174 0.013
rhythmic process GO:0048511 174 0.013
response to drug GO:0042493 75 0.013
Rat
protein modification by small protein conjugation or removal GO:0070647 207 0.012
cell matrix adhesion GO:0007160 68 0.012
regulation of multi organism process GO:0043900 111 0.012
methylation GO:0032259 134 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
Rat
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
branching involved in ureteric bud morphogenesis GO:0001658 56 0.012
progesterone biosynthetic process GO:0006701 1 0.012
positive regulation of phospholipase activity GO:0010518 3 0.012
glycerolipid biosynthetic process GO:0045017 50 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
monosaccharide biosynthetic process GO:0046364 44 0.012
regulation of stem cell proliferation GO:0072091 78 0.012
regulation of complement activation GO:0030449 7 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of complement activation classical pathway GO:0030450 1 0.012
cytoplasmic transport GO:0016482 234 0.012
calcitriol biosynthetic process from calciol GO:0036378 3 0.012
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.012
regulation of map kinase activity GO:0043405 120 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
endocrine system development GO:0035270 98 0.011
Rat
epithelial cell development GO:0002064 159 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.011
sperm egg recognition GO:0035036 37 0.011
nucleoside metabolic process GO:0009116 246 0.011
response to corticosterone GO:0051412 1 0.011
extracellular matrix organization GO:0030198 147 0.011
Mouse
hormone secretion GO:0046879 128 0.011
epithelial cell migration GO:0010631 63 0.011
Mouse
macromolecule glycosylation GO:0043413 55 0.011
sensory perception of umami taste GO:0050917 4 0.011
asymmetric stem cell division GO:0098722 3 0.011
protein secretion GO:0009306 111 0.011
membrane organization GO:0061024 245 0.011
regulation of membrane potential GO:0042391 192 0.011
response to peptide GO:1901652 136 0.011
response to starvation GO:0042594 65 0.011
cation homeostasis GO:0055080 212 0.011
innate immune response in mucosa GO:0002227 3 0.011
glucose catabolic process GO:0006007 3 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
regulation of epithelial cell migration GO:0010632 35 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
response to light stimulus GO:0009416 135 0.011
glycosylation GO:0070085 62 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of body fluid levels GO:0050878 162 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
intracellular protein transport GO:0006886 204 0.010
positive regulation of renal sodium excretion GO:0035815 2 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
glucose metabolic process GO:0006006 92 0.010
kidney epithelium development GO:0072073 121 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
organelle assembly GO:0070925 177 0.010
endothelial cell development GO:0001885 20 0.010
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
cell killing GO:0001906 67 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.010
glial cell development GO:0021782 54 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
ion transmembrane transport GO:0034220 361 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
positive regulation of phospholipase c activity GO:0010863 2 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
phosphatidylinositol mediated signaling GO:0048015 41 0.010

Cyp17a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.012
Human
neurodegenerative disease DOID:1289 0 0.012