Mus musculus

87 known processes

Dchs1

dachsous 1 (Drosophila)

(Aliases: Gm165,C130033F22Rik,FIB1,CDH25,3110041P15Rik,PCDH16)

Dchs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.740
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.621
ossification involved in bone maturation GO:0043931 12 0.570
nephron epithelium morphogenesis GO:0072088 68 0.506
nephron tubule morphogenesis GO:0072078 68 0.425
branching morphogenesis of an epithelial tube GO:0048754 159 0.425
ureteric bud development GO:0001657 94 0.317
nephron morphogenesis GO:0072028 69 0.301
renal tubule development GO:0061326 87 0.294
mesonephric tubule morphogenesis GO:0072171 63 0.290
mesonephric tubule development GO:0072164 94 0.284
developmental maturation GO:0021700 193 0.261
cell adhesion GO:0007155 329 0.232
bone development GO:0060348 120 0.216
ureteric bud morphogenesis GO:0060675 62 0.216
organ maturation GO:0048799 17 0.215
skeletal system development GO:0001501 356 0.207
morphogenesis of a branching structure GO:0001763 203 0.185
regulation of hydrolase activity GO:0051336 246 0.167
positive regulation of nervous system development GO:0051962 221 0.162
kidney epithelium development GO:0072073 121 0.150
urogenital system development GO:0001655 261 0.144
anatomical structure maturation GO:0071695 49 0.139
membrane organization GO:0061024 245 0.132
mesonephric epithelium development GO:0072163 94 0.132
ossification GO:0001503 216 0.131
heart morphogenesis GO:0003007 178 0.129
branching involved in ureteric bud morphogenesis GO:0001658 56 0.126
positive regulation of cell development GO:0010720 237 0.123
kidney development GO:0001822 213 0.108
inner ear receptor stereocilium organization GO:0060122 23 0.107
extracellular structure organization GO:0043062 148 0.103
negative regulation of cell proliferation GO:0008285 296 0.093
plasma membrane organization GO:0007009 90 0.091
mechanoreceptor differentiation GO:0042490 67 0.087
forebrain development GO:0030900 302 0.083
nephron tubule development GO:0072080 84 0.083
nephron development GO:0072006 109 0.079
endomembrane system organization GO:0010256 147 0.079
inner ear receptor cell differentiation GO:0060113 61 0.075
regulation of neuron differentiation GO:0045664 281 0.073
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.069
purine nucleotide metabolic process GO:0006163 302 0.068
recognition of apoptotic cell GO:0043654 3 0.066
gtp catabolic process GO:0006184 143 0.065
metanephros development GO:0001656 79 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.060
guanosine containing compound metabolic process GO:1901068 144 0.057
extracellular matrix organization GO:0030198 147 0.057
cell cell adhesion GO:0098609 41 0.055
negative regulation of cellular amine metabolic process GO:0033239 1 0.055
metanephric tubule development GO:0072170 18 0.055
regulation of nucleotide metabolic process GO:0006140 169 0.054
purine containing compound metabolic process GO:0072521 311 0.051
epithelial tube morphogenesis GO:0060562 303 0.050
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.049
inner ear receptor cell development GO:0060119 39 0.049
positive regulation of gtp catabolic process GO:0033126 85 0.048
cell substrate adhesion GO:0031589 130 0.048
telencephalon development GO:0021537 186 0.047
rho protein signal transduction GO:0007266 32 0.046
regulation of purine nucleotide catabolic process GO:0033121 122 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.046
purine nucleoside metabolic process GO:0042278 241 0.045
positive regulation of cell projection organization GO:0031346 95 0.045
cerebral cortex development GO:0021987 86 0.045
positive regulation of neuron differentiation GO:0045666 141 0.043
positive regulation of cellular catabolic process GO:0031331 148 0.042
purine containing compound catabolic process GO:0072523 213 0.042
organic cyclic compound catabolic process GO:1901361 295 0.040
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.040
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.039
regulation of neuron projection development GO:0010975 169 0.039
heterocycle catabolic process GO:0046700 280 0.039
ameboidal type cell migration GO:0001667 128 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
glycosyl compound catabolic process GO:1901658 206 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
cellular amino acid metabolic process GO:0006520 103 0.038
carbohydrate derivative catabolic process GO:1901136 231 0.038
positive regulation of gtpase activity GO:0043547 85 0.036
regulation of ras gtpase activity GO:0032318 88 0.036
ribonucleoside triphosphate metabolic process GO:0009199 220 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
trabecula morphogenesis GO:0061383 40 0.034
purine ribonucleoside catabolic process GO:0046130 205 0.033
glycosyl compound metabolic process GO:1901657 246 0.033
nucleotide catabolic process GO:0009166 217 0.033
metanephric nephron tubule development GO:0072234 16 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
amine metabolic process GO:0009308 45 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
pallium development GO:0021543 120 0.032
cell differentiation involved in metanephros development GO:0072202 12 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
morphogenesis of a branching epithelium GO:0061138 193 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
regulation of striated muscle cell differentiation GO:0051153 81 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.030
regulation of ras protein signal transduction GO:0046578 114 0.030
positive regulation of protein modification process GO:0031401 299 0.030
peptide transport GO:0015833 133 0.030
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.030
neuron projection guidance GO:0097485 141 0.029
purine nucleoside catabolic process GO:0006152 205 0.029
cellular component assembly involved in morphogenesis GO:0010927 139 0.029
peptidyl amino acid modification GO:0018193 336 0.029
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.028
aromatic compound catabolic process GO:0019439 286 0.028
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.028
compound eye development GO:0048749 1 0.028
renal system development GO:0072001 225 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
limb development GO:0060173 166 0.028
ribose phosphate metabolic process GO:0019693 291 0.027
nucleotide metabolic process GO:0009117 332 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
organophosphate catabolic process GO:0046434 232 0.027
lateral inhibition GO:0046331 1 0.027
muscle tissue development GO:0060537 308 0.026
positive regulation of nucleotide metabolic process GO:0045981 114 0.026
epithelial tube formation GO:0072175 130 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
regulation of metanephros development GO:0072215 15 0.025
negative regulation of interleukin 5 production GO:0032714 4 0.025
sulfur compound metabolic process GO:0006790 100 0.025
defense response to other organism GO:0098542 197 0.025
immune effector process GO:0002252 321 0.025
female gamete generation GO:0007292 74 0.025
negative regulation of synapse assembly GO:0051964 3 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
regulation of gtp catabolic process GO:0033124 113 0.025
embryonic limb morphogenesis GO:0030326 126 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
regulation of organelle organization GO:0033043 289 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
dendrite development GO:0016358 115 0.024
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.024
gtp metabolic process GO:0046039 144 0.024
male gamete generation GO:0048232 285 0.024
regulation of cellular response to growth factor stimulus GO:0090287 82 0.023
sympathetic neuron projection extension GO:0097490 4 0.023
rac protein signal transduction GO:0016601 13 0.023
heart trabecula morphogenesis GO:0061384 26 0.023
regulation of cell adhesion GO:0030155 154 0.023
spermatogenesis GO:0007283 284 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
regulation of cellular response to stress GO:0080135 159 0.022
positive regulation of cell death GO:0010942 224 0.022
regulation of cell projection organization GO:0031344 206 0.022
regulation of cell growth GO:0001558 91 0.021
formation of organ boundary GO:0010160 1 0.021
neuron migration GO:0001764 122 0.021
cerebellar granule cell precursor tangential migration GO:0021935 1 0.021
cellular ketone metabolic process GO:0042180 84 0.021
apoptotic signaling pathway GO:0097190 306 0.021
regulation of protein binding GO:0043393 60 0.020
trunk neural crest cell migration GO:0036484 4 0.020
metanephric nephron epithelium development GO:0072243 19 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
metanephric epithelium development GO:0072207 21 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
positive regulation of neuron projection development GO:0010976 79 0.020
leukocyte differentiation GO:0002521 342 0.020
neural tube development GO:0021915 160 0.020
skeletal system morphogenesis GO:0048705 203 0.020
wnt signaling pathway GO:0016055 188 0.020
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.020
regulation of cellular component size GO:0032535 121 0.020
negative regulation of cell activation GO:0050866 111 0.020
skin development GO:0043588 220 0.020
vagus nerve development GO:0021564 3 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
positive regulation of cellular component biogenesis GO:0044089 94 0.019
cell type specific apoptotic process GO:0097285 268 0.019
epithelial cell differentiation involved in kidney development GO:0035850 23 0.019
retina development in camera type eye GO:0060041 119 0.019
single organism cell adhesion GO:0098602 156 0.019
cell differentiation involved in kidney development GO:0061005 33 0.019
defense response to bacterium GO:0042742 119 0.018
segmentation GO:0035282 93 0.018
nuclear division GO:0000280 158 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
regulation of kidney development GO:0090183 40 0.018
nitrogen compound transport GO:0071705 271 0.018
lung development GO:0030324 164 0.018
chondroitin sulfate metabolic process GO:0030204 17 0.017
nephron tubule epithelial cell differentiation GO:0072160 11 0.017
negative regulation of neuron differentiation GO:0045665 101 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
positive regulation of ras gtpase activity GO:0032320 65 0.017
negative regulation of cell development GO:0010721 169 0.017
olfactory bulb axon guidance GO:0071678 1 0.017
tube formation GO:0035148 140 0.017
regulation of axon extension GO:0030516 43 0.017
organ growth GO:0035265 117 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
synapse assembly GO:0007416 56 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
tube closure GO:0060606 91 0.016
positive regulation of neuron projection regeneration GO:0070572 2 0.016
ear development GO:0043583 200 0.016
oxidation reduction process GO:0055114 342 0.016
macromolecule catabolic process GO:0009057 281 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
germ cell development GO:0007281 185 0.016
negative regulation of smooth muscle cell migration GO:0014912 2 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.015
axon guidance GO:0007411 141 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
myeloid leukocyte migration GO:0097529 57 0.015
chemotaxis GO:0006935 247 0.015
leukocyte migration GO:0050900 124 0.015
compartment pattern specification GO:0007386 4 0.015
regulation of anatomical structure size GO:0090066 178 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.015
regulation of rho protein signal transduction GO:0035023 71 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
facioacoustic ganglion development GO:1903375 3 0.015
kidney morphogenesis GO:0060993 83 0.015
regulation of response to wounding GO:1903034 189 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
skeletal muscle cell differentiation GO:0035914 66 0.015
negative regulation of immune system process GO:0002683 209 0.015
mesodermal cell migration GO:0008078 4 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
regulation of neuron migration GO:2001222 22 0.015
blood circulation GO:0008015 195 0.014
sensory organ morphogenesis GO:0090596 242 0.014
exocrine system development GO:0035272 45 0.014
protein catabolic process GO:0030163 221 0.014
negative regulation of neuron projection regeneration GO:0070571 3 0.014
neuromuscular process GO:0050905 99 0.014
nucleoside catabolic process GO:0009164 206 0.014
organelle assembly GO:0070925 177 0.014
circulatory system process GO:0003013 197 0.014
microtubule based process GO:0007017 236 0.014
dorsal ventral axon guidance GO:0033563 3 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of growth GO:0045927 104 0.014
postganglionic parasympathetic nervous system development GO:0021784 2 0.014
nucleoside metabolic process GO:0009116 246 0.014
regulation of cell activation GO:0050865 289 0.014
sensory system development GO:0048880 3 0.014
positive regulation of muscle cell differentiation GO:0051149 39 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
neuron apoptotic process GO:0051402 142 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.014
regulation of system process GO:0044057 200 0.014
muscle cell differentiation GO:0042692 261 0.014
t cell activation GO:0042110 289 0.014
limb morphogenesis GO:0035108 149 0.014
chromatin organization GO:0006325 206 0.014
gonad development GO:0008406 141 0.013
eosinophil migration GO:0072677 3 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
glycoprotein metabolic process GO:0009100 116 0.013
myotube differentiation GO:0014902 105 0.013
regulation of cell motility GO:2000145 236 0.013
muscle cell proliferation GO:0033002 52 0.013
response to organonitrogen compound GO:0010243 246 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
regulation of binding GO:0051098 111 0.013
cell growth GO:0016049 130 0.013
chemorepulsion of branchiomotor axon GO:0021793 1 0.013
fat cell differentiation GO:0045444 160 0.013
pigmentation GO:0043473 71 0.013
hindbrain tangential cell migration GO:0021934 2 0.013
primary neural tube formation GO:0014020 95 0.013
inflammatory response GO:0006954 244 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
fasciculation of motor neuron axon GO:0097156 2 0.013
mucopolysaccharide metabolic process GO:1903510 25 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.013
neural tube formation GO:0001841 108 0.013
mesonephros development GO:0001823 97 0.013
osteoclast differentiation GO:0030316 62 0.013
retina morphogenesis in camera type eye GO:0060042 45 0.013
regulation of cellular catabolic process GO:0031329 242 0.012
camera type eye development GO:0043010 266 0.012
mapk cascade GO:0000165 281 0.012
negative regulation of nervous system development GO:0051961 156 0.012
positive regulation of response to wounding GO:1903036 66 0.012
axonogenesis GO:0007409 274 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
development of primary sexual characteristics GO:0045137 143 0.012
myosin filament assembly GO:0031034 2 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
smoothened signaling pathway GO:0007224 105 0.012
trunk segmentation GO:0035290 4 0.012
intracellular protein transport GO:0006886 204 0.012
regulation of muscle tissue development GO:1901861 97 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
regulation of neuron death GO:1901214 134 0.012
synaptic transmission GO:0007268 329 0.012
ras protein signal transduction GO:0007265 77 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
somite development GO:0061053 81 0.012
glycosaminoglycan metabolic process GO:0030203 34 0.012
regulation of protein localization GO:0032880 231 0.012
neuron death GO:0070997 154 0.012
glucose transport GO:0015758 56 0.012
regionalization GO:0003002 337 0.012
branchiomotor neuron axon guidance GO:0021785 7 0.012
cellular macromolecule catabolic process GO:0044265 206 0.011
endothelial cell migration GO:0043542 44 0.011
vagus nerve morphogenesis GO:0021644 2 0.011
neural retina development GO:0003407 41 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
trabecula formation GO:0060343 24 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
connective tissue development GO:0061448 179 0.011
negative regulation of chemotaxis GO:0050922 11 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
transmembrane transport GO:0055085 412 0.011
regulation of transferase activity GO:0051338 263 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.011
regulation of membrane potential GO:0042391 192 0.011
monosaccharide metabolic process GO:0005996 106 0.011
establishment of planar polarity GO:0001736 28 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
inter male aggressive behavior GO:0002121 3 0.011
negative regulation of wnt signaling pathway GO:0030178 73 0.011
oogenesis GO:0048477 56 0.011
defecation GO:0030421 1 0.011
positive regulation of phospholipase activity GO:0010518 3 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
negative regulation of cell projection organization GO:0031345 56 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.011
negative regulation of growth GO:0045926 99 0.011
organelle fission GO:0048285 170 0.011
regulation of t cell activation GO:0050863 170 0.011
negative regulation of molecular function GO:0044092 258 0.011
positive regulation of cell growth GO:0030307 33 0.011
pharynx development GO:0060465 1 0.010
midgut development GO:0007494 4 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
ventral trunk neural crest cell migration GO:0036486 4 0.010
response to transforming growth factor beta GO:0071559 88 0.010
positive regulation of immune effector process GO:0002699 107 0.010
positive regulation of transferase activity GO:0051347 167 0.010
regulation of ossification GO:0030278 112 0.010
antimicrobial peptide production GO:0002775 2 0.010
regulation of extent of cell growth GO:0061387 52 0.010
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.010
carbohydrate metabolic process GO:0005975 230 0.010
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.010

Dchs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.031
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
muscle tissue disease DOID:66 0 0.031
nervous system disease DOID:863 0 0.015
epilepsy syndrome DOID:1826 0 0.014
central nervous system disease DOID:331 0 0.014
brain disease DOID:936 0 0.014
electroclinical syndrome DOID:0050701 0 0.014