Mus musculus

27 known processes

Ddb1

damage specific DNA binding protein 1

(Aliases: p127-Ddb1,127kDa,AA408517)

Ddb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based process GO:0007017 236 0.369
protein ubiquitination GO:0016567 171 0.312
Human
protein modification by small protein conjugation GO:0032446 187 0.304
Human
microtubule cytoskeleton organization GO:0000226 157 0.246
cytoplasmic transport GO:0016482 234 0.176
cellular amino acid metabolic process GO:0006520 103 0.168
cellular amine metabolic process GO:0044106 44 0.135
nuclear division GO:0000280 158 0.122
protein modification by small protein conjugation or removal GO:0070647 207 0.121
Human
dna repair GO:0006281 107 0.116
Human
cellular response to dna damage stimulus GO:0006974 207 0.113
Human
mitotic cell cycle GO:0000278 195 0.112
Human
endocytosis GO:0006897 168 0.112
Worm
metal ion homeostasis GO:0055065 189 0.104
amine metabolic process GO:0009308 45 0.104
spermatogenesis GO:0007283 284 0.100
dna metabolic process GO:0006259 303 0.097
Human
protein localization to organelle GO:0033365 185 0.092
modification dependent macromolecule catabolic process GO:0043632 133 0.089
Human
cellular protein catabolic process GO:0044257 155 0.086
Human
positive regulation of protein modification process GO:0031401 299 0.085
membrane organization GO:0061024 245 0.082
maintenance of location GO:0051235 89 0.080
male gamete generation GO:0048232 285 0.079
negative regulation of protein metabolic process GO:0051248 282 0.079
cytoskeleton dependent intracellular transport GO:0030705 50 0.071
cation homeostasis GO:0055080 212 0.068
modification dependent protein catabolic process GO:0019941 133 0.066
Human
positive regulation of apoptotic process GO:0043065 217 0.065
macromolecule catabolic process GO:0009057 281 0.064
Human Worm
cellular homeostasis GO:0019725 240 0.063
proteasomal protein catabolic process GO:0010498 98 0.061
Human
organelle localization GO:0051640 179 0.061
establishment of protein localization to organelle GO:0072594 118 0.059
regulation of neuron differentiation GO:0045664 281 0.057
endomembrane system organization GO:0010256 147 0.057
nuclear import GO:0051170 95 0.056
transmembrane transport GO:0055085 412 0.054
cation transmembrane transport GO:0098655 266 0.053
ubiquitin dependent protein catabolic process GO:0006511 129 0.053
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
mitotic cell cycle process GO:1903047 159 0.052
Human
protein localization to nucleus GO:0034504 121 0.052
regulation of mapk cascade GO:0043408 248 0.050
cellular ketone metabolic process GO:0042180 84 0.049
cation transport GO:0006812 399 0.049
axonogenesis GO:0007409 274 0.049
protein catabolic process GO:0030163 221 0.049
Human Worm
action potential GO:0001508 78 0.048
ribonucleotide metabolic process GO:0009259 291 0.045
meiotic cell cycle GO:0051321 122 0.044
ribonucleotide catabolic process GO:0009261 208 0.043
regulation of intracellular transport GO:0032386 159 0.042
regulation of protein kinase activity GO:0045859 232 0.041
nucleocytoplasmic transport GO:0006913 139 0.041
translation GO:0006412 93 0.041
positive regulation of cell death GO:0010942 224 0.041
regulation of establishment of protein localization GO:0070201 181 0.041
protein modification by small protein removal GO:0070646 21 0.040
protein import GO:0017038 101 0.039
meiotic nuclear division GO:0007126 115 0.039
transmission of nerve impulse GO:0019226 76 0.039
small gtpase mediated signal transduction GO:0007264 97 0.038
purine containing compound metabolic process GO:0072521 311 0.037
regulation of protein localization GO:0032880 231 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.037
cellular ion homeostasis GO:0006873 165 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
intracellular protein transport GO:0006886 204 0.035
protein complex disassembly GO:0043241 40 0.035
nucleotide metabolic process GO:0009117 332 0.035
purine nucleoside catabolic process GO:0006152 205 0.035
cellular component assembly involved in morphogenesis GO:0010927 139 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.034
mitotic cytokinesis GO:0000281 4 0.034
activation of mapkkk activity GO:0000185 1 0.034
renal system development GO:0072001 225 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
cell growth GO:0016049 130 0.032
organophosphate biosynthetic process GO:0090407 122 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
Human
purine containing compound catabolic process GO:0072523 213 0.031
regulation of mitotic cell cycle GO:0007346 126 0.031
Human
multicellular organismal signaling GO:0035637 91 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
regulation of protein targeting GO:1903533 61 0.031
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.029
spindle organization GO:0007051 28 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
protein import into nucleus GO:0006606 95 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
body morphogenesis GO:0010171 45 0.028
embryonic organ morphogenesis GO:0048562 276 0.028
regulation of proteolysis GO:0030162 164 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
Human
dna dealkylation GO:0035510 11 0.027
organelle assembly GO:0070925 177 0.027
positive regulation of nervous system development GO:0051962 221 0.027
formation of organ boundary GO:0010160 1 0.027
regulation of wnt signaling pathway GO:0030111 123 0.027
regulation of cytoplasmic transport GO:1903649 112 0.027
regulation of protein localization to nucleus GO:1900180 60 0.027
synaptic transmission GO:0007268 329 0.026
nuclear transport GO:0051169 139 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
meiotic cell cycle process GO:1903046 77 0.026
neuronal action potential GO:0019228 54 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
inclusion body assembly GO:0070841 3 0.026
peptidyl amino acid modification GO:0018193 336 0.025
negative regulation of cell cycle GO:0045786 123 0.025
covalent chromatin modification GO:0016569 163 0.025
Human
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
protein secretion GO:0009306 111 0.024
regulation of metal ion transport GO:0010959 106 0.024
single organism nuclear import GO:1902593 95 0.024
regulation of cell cycle GO:0051726 281 0.024
Human
regulation of kinase activity GO:0043549 249 0.024
ras protein signal transduction GO:0007265 77 0.024
cell type specific apoptotic process GO:0097285 268 0.024
regulation of protein import into nucleus GO:0042306 52 0.024
negative regulation of organelle organization GO:0010639 90 0.024
carbohydrate metabolic process GO:0005975 230 0.024
cell division GO:0051301 120 0.023
circadian regulation of gene expression GO:0032922 48 0.023
divalent inorganic cation homeostasis GO:0072507 138 0.023
fat cell differentiation GO:0045444 160 0.023
ion transmembrane transport GO:0034220 361 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.022
protein maturation GO:0051604 176 0.022
positive regulation of cell projection organization GO:0031346 95 0.022
calcium ion homeostasis GO:0055074 127 0.022
protein targeting GO:0006605 143 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
nucleoside metabolic process GO:0009116 246 0.022
single fertilization GO:0007338 82 0.022
protein processing GO:0016485 163 0.022
wnt signaling pathway GO:0016055 188 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.021
Human
negative regulation of growth GO:0045926 99 0.021
negative regulation of protein modification process GO:0031400 163 0.021
mrna metabolic process GO:0016071 84 0.021
ameboidal type cell migration GO:0001667 128 0.021
stem cell differentiation GO:0048863 268 0.021
sensory perception GO:0007600 245 0.021
cellular chemical homeostasis GO:0055082 215 0.020
asymmetric neuroblast division GO:0055059 1 0.020
regulation of nucleocytoplasmic transport GO:0046822 73 0.020
nucleotide catabolic process GO:0009166 217 0.020
cell recognition GO:0008037 83 0.020
organelle fission GO:0048285 170 0.020
regulation of cell size GO:0008361 72 0.020
regulation of vitamin d receptor signaling pathway GO:0070562 2 0.020
methylation GO:0032259 134 0.020
response to light stimulus GO:0009416 135 0.020
Human
kidney development GO:0001822 213 0.020
dendrite development GO:0016358 115 0.020
negative regulation of molecular function GO:0044092 258 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
nuclear export GO:0051168 34 0.019
cellular protein complex assembly GO:0043623 116 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
microtubule polymerization or depolymerization GO:0031109 26 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
regulation of neuron projection development GO:0010975 169 0.019
protein polyubiquitination GO:0000209 33 0.019
adult behavior GO:0030534 135 0.019
regulation of cell activation GO:0050865 289 0.019
positive regulation of secretion GO:0051047 130 0.019
locomotory behavior GO:0007626 195 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.018
multicellular organism growth GO:0035264 161 0.018
cellular protein complex disassembly GO:0043624 36 0.018
developmental growth involved in morphogenesis GO:0060560 138 0.018
ensheathment of neurons GO:0007272 76 0.018
hexose metabolic process GO:0019318 98 0.018
sequestering of calcium ion GO:0051208 18 0.018
mitotic nuclear division GO:0007067 48 0.018
regulation of membrane potential GO:0042391 192 0.018
germ cell development GO:0007281 185 0.018
regulation of cell projection organization GO:0031344 206 0.018
regulation of histone modification GO:0031056 56 0.018
regulation of organelle organization GO:0033043 289 0.018
protein localization to membrane GO:0072657 108 0.018
vesicle organization GO:0016050 60 0.018
organonitrogen compound catabolic process GO:1901565 264 0.017
divalent metal ion transport GO:0070838 172 0.017
regulation of cell growth GO:0001558 91 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
viral life cycle GO:0019058 36 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
regulation of transcription factor import into nucleus GO:0042990 24 0.017
transition metal ion homeostasis GO:0055076 54 0.017
regulation of ion transmembrane transport GO:0034765 119 0.017
negative regulation of synapse assembly GO:0051964 3 0.017
regulation of secretion by cell GO:1903530 249 0.017
mapk cascade GO:0000165 281 0.017
negative regulation of transferase activity GO:0051348 85 0.017
regulation of cellular response to stress GO:0080135 159 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
mesenchyme development GO:0060485 152 0.017
mesenchymal cell differentiation GO:0048762 107 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
t cell activation GO:0042110 289 0.017
oxidation reduction process GO:0055114 342 0.016
positive regulation of cell motility GO:2000147 116 0.016
regulation of protein transport GO:0051223 163 0.016
sensory organ morphogenesis GO:0090596 242 0.016
nitrogen compound transport GO:0071705 271 0.016
vitamin d receptor signaling pathway GO:0070561 2 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
positive regulation of cell development GO:0010720 237 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
positive regulation of synaptic plasticity GO:0031915 4 0.016
neuron projection guidance GO:0097485 141 0.016
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.016
skeletal system development GO:0001501 356 0.016
cell adhesion GO:0007155 329 0.016
aromatic compound catabolic process GO:0019439 286 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
establishment of organelle localization GO:0051656 122 0.015
chromatin modification GO:0016568 187 0.015
Human
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.015
adult locomotory behavior GO:0008344 91 0.015
wound healing GO:0042060 157 0.015
positive regulation of transferase activity GO:0051347 167 0.015
protein autophosphorylation GO:0046777 61 0.015
pigmentation GO:0043473 71 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
negative regulation of neuron death GO:1901215 98 0.015
response to inorganic substance GO:0010035 96 0.014
negative regulation of kinase activity GO:0033673 81 0.014
interspecies interaction between organisms GO:0044419 83 0.014
lipid localization GO:0010876 126 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
homeostasis of number of cells GO:0048872 210 0.014
cytoplasmic translational initiation GO:0002183 3 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
regulation of translation GO:0006417 71 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
gene silencing by rna GO:0031047 19 0.014
response to oxygen levels GO:0070482 62 0.014
response to endoplasmic reticulum stress GO:0034976 53 0.014
immune effector process GO:0002252 321 0.014
positive regulation of protein transport GO:0051222 93 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
aggresome assembly GO:0070842 2 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
negative regulation of nervous system development GO:0051961 156 0.014
viral process GO:0016032 41 0.014
protein n linked glycosylation GO:0006487 12 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
neuron apoptotic process GO:0051402 142 0.014
attachment of spindle microtubules to kinetochore GO:0008608 4 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
response to radiation GO:0009314 165 0.013
Human
asymmetric stem cell division GO:0098722 3 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
vesicle localization GO:0051648 86 0.013
chemotaxis GO:0006935 247 0.013
regulation of canonical wnt signaling pathway GO:0060828 82 0.013
positive regulation of chromosome organization GO:2001252 33 0.013
regulation of cellular protein catabolic process GO:1903362 61 0.013
heterocycle catabolic process GO:0046700 280 0.013
cellular response to acid chemical GO:0071229 68 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.013
organic anion transport GO:0015711 137 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
misfolded protein transport GO:0070843 1 0.013
cellular response to lipid GO:0071396 145 0.013
response to acid chemical GO:0001101 111 0.013
trna metabolic process GO:0006399 11 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of hormone levels GO:0010817 211 0.012
muscle system process GO:0003012 141 0.012
epithelial cell proliferation GO:0050673 174 0.012
positive regulation of protein localization to nucleus GO:1900182 30 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
positive regulation of cell activation GO:0050867 158 0.012
connective tissue development GO:0061448 179 0.012
urogenital system development GO:0001655 261 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
positive regulation of jak stat cascade GO:0046427 22 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
regulation of chromatin organization GO:1902275 57 0.012
placenta development GO:0001890 140 0.012
translational initiation GO:0006413 24 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
leukocyte differentiation GO:0002521 342 0.012
copii coated vesicle budding GO:0090114 2 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
neural crest cell development GO:0014032 48 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of protein secretion GO:0050708 82 0.011
regulation of secretion GO:0051046 274 0.011
regulation of cell motility GO:2000145 236 0.011
lymphocyte proliferation GO:0046651 164 0.011
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
response to temperature stimulus GO:0009266 55 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
rna interference GO:0016246 2 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
developmental maturation GO:0021700 193 0.011
neural precursor cell proliferation GO:0061351 121 0.011
positive regulation of intracellular protein transport GO:0090316 42 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
positive regulation of cytoplasmic transport GO:1903651 40 0.011
forebrain development GO:0030900 302 0.011
microtubule based transport GO:0010970 50 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
transcription factor import into nucleus GO:0042991 26 0.011
embryonic skeletal system development GO:0048706 120 0.011
transdifferentiation GO:0060290 1 0.011
regulation of cell division GO:0051302 76 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
cell fate commitment GO:0045165 210 0.011
protein oligomerization GO:0051259 67 0.011
lymphocyte homeostasis GO:0002260 64 0.011
regulation of anatomical structure size GO:0090066 178 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of cellular component size GO:0032535 121 0.011
muscle tissue development GO:0060537 308 0.010
circulatory system process GO:0003013 197 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
extracellular structure organization GO:0043062 148 0.010
carbohydrate homeostasis GO:0033500 128 0.010
histone deacetylation GO:0016575 26 0.010
neural retina development GO:0003407 41 0.010
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010
regulation of transmembrane transport GO:0034762 128 0.010
macromolecule deacylation GO:0098732 37 0.010
spermatid differentiation GO:0048515 115 0.010
apoptotic signaling pathway GO:0097190 306 0.010
jak stat cascade GO:0007259 42 0.010
dna conformation change GO:0071103 37 0.010
positive regulation of chromatin modification GO:1903310 28 0.010
double strand break repair GO:0006302 48 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
regulation of cell migration GO:0030334 219 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010

Ddb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
nervous system disease DOID:863 0 0.091
neuropathy DOID:870 0 0.091
neuromuscular disease DOID:440 0 0.069
central nervous system disease DOID:331 0 0.035
neurodegenerative disease DOID:1289 0 0.026
charcot marie tooth disease DOID:10595 0 0.024
nephritis DOID:10952 0 0.020
glomerulonephritis DOID:2921 0 0.020
focal segmental glomerulosclerosis DOID:1312 0 0.020
kidney disease DOID:557 0 0.020
urinary system disease DOID:18 0 0.020
glomerulosclerosis DOID:0050851 0 0.020
sensory system disease DOID:0050155 0 0.019
disease of mental health DOID:150 0 0.017
charcot marie tooth disease type 2 DOID:0050539 0 0.015
eye and adnexa disease DOID:1492 0 0.011
osteochondrodysplasia DOID:2256 0 0.010
bone development disease DOID:0080006 0 0.010
bone disease DOID:0080001 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010
cardiovascular system disease DOID:1287 0 0.010