Mus musculus

12 known processes

Defb2

defensin beta 2

(Aliases: MGC129141,MGC129140,BD-2)

Defb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 266 0.086
transmembrane transport GO:0055085 412 0.071
social behavior GO:0035176 21 0.064
organic hydroxy compound transport GO:0015850 93 0.056
nitrogen compound transport GO:0071705 271 0.055
ion transmembrane transport GO:0034220 361 0.041
regulation of blood pressure GO:0008217 93 0.036
multi multicellular organism process GO:0044706 109 0.036
spermatogenesis GO:0007283 284 0.035
reactive oxygen species metabolic process GO:0072593 84 0.034
cellular lipid metabolic process GO:0044255 323 0.034
regulation of feeding behavior GO:0060259 3 0.033
kidney development GO:0001822 213 0.033
positive regulation of growth GO:0045927 104 0.032
embryonic organ morphogenesis GO:0048562 276 0.031
visual perception GO:0007601 52 0.031
positive regulation of secretion GO:0051047 130 0.030
regulation of secretion GO:0051046 274 0.030
cellular amine metabolic process GO:0044106 44 0.029
amide transport GO:0042886 138 0.029
response to molecule of bacterial origin GO:0002237 143 0.028
norepinephrine transport GO:0015874 2 0.028
multicellular organism growth GO:0035264 161 0.028
urogenital system development GO:0001655 261 0.028
neurotransmitter transport GO:0006836 76 0.028
apoptotic signaling pathway GO:0097190 306 0.028
response to amino acid GO:0043200 37 0.027
erythrocyte differentiation GO:0030218 88 0.027
dopamine catabolic process GO:0042420 4 0.027
regulation of interleukin 6 production GO:0032675 55 0.027
muscle system process GO:0003012 141 0.026
regulation of lipid metabolic process GO:0019216 118 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
fertilization GO:0009566 127 0.026
regulation of angiotensin levels in blood GO:0002002 4 0.026
cytokine production GO:0001816 319 0.024
regulation of multi organism process GO:0043900 111 0.024
negative regulation of sterol transport GO:0032372 4 0.024
amine metabolic process GO:0009308 45 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.023
peptide transport GO:0015833 133 0.023
response to organic cyclic compound GO:0014070 198 0.022
regulation of cell cycle GO:0051726 281 0.022
response to organonitrogen compound GO:0010243 246 0.022
positive regulation of ion transport GO:0043270 65 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
interspecies interaction between organisms GO:0044419 83 0.022
cellular response to biotic stimulus GO:0071216 92 0.021
oxidation reduction process GO:0055114 342 0.021
regulation of neurotransmitter levels GO:0001505 87 0.021
somatotropin secreting cell differentiation GO:0060126 4 0.021
epithelial cell proliferation GO:0050673 174 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
circadian sleep wake cycle non rem sleep GO:0042748 2 0.020
sensory perception of sound GO:0007605 97 0.020
camera type eye development GO:0043010 266 0.020
protein catabolic process GO:0030163 221 0.020
response to lipopolysaccharide GO:0032496 128 0.020
endocrine process GO:0050886 39 0.020
immune effector process GO:0002252 321 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
cell growth GO:0016049 130 0.019
macromolecule catabolic process GO:0009057 281 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.018
blood circulation GO:0008015 195 0.018
cellular ketone metabolic process GO:0042180 84 0.018
gland development GO:0048732 330 0.018
regulation of secretion by cell GO:1903530 249 0.018
single fertilization GO:0007338 82 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
regulation of protein complex assembly GO:0043254 83 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.017
metanephric loop of henle development GO:0072236 4 0.017
regulation of systemic arterial blood pressure GO:0003073 61 0.017
regulation of hormone levels GO:0010817 211 0.017
regulation of protein transport GO:0051223 163 0.017
interleukin 6 production GO:0032635 58 0.017
spermatid development GO:0007286 108 0.017
regulation of membrane potential GO:0042391 192 0.017
male gamete generation GO:0048232 285 0.017
dephosphorylation GO:0016311 129 0.016
body fluid secretion GO:0007589 53 0.016
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.016
regulation of circadian sleep wake cycle GO:0042749 3 0.016
germ cell development GO:0007281 185 0.016
endocytosis GO:0006897 168 0.016
cellular amino acid metabolic process GO:0006520 103 0.016
regulation of cellular response to stress GO:0080135 159 0.016
circulatory system process GO:0003013 197 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
protein secretion GO:0009306 111 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
myeloid cell homeostasis GO:0002262 114 0.015
alpha amino acid metabolic process GO:1901605 59 0.015
intraspecies interaction between organisms GO:0051703 21 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
l amino acid transport GO:0015807 32 0.015
carboxylic acid transport GO:0046942 100 0.014
gonad development GO:0008406 141 0.014
response to inorganic substance GO:0010035 96 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
lactation GO:0007595 25 0.014
glycine transport GO:0015816 4 0.014
negative regulation of multi organism process GO:0043901 68 0.014
cardiac chamber morphogenesis GO:0003206 93 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
tube formation GO:0035148 140 0.014
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.014
cation transport GO:0006812 399 0.014
negative regulation of t cell cytokine production GO:0002725 1 0.014
sterol homeostasis GO:0055092 45 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
heart contraction GO:0060047 93 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
regulation of t helper 2 cell cytokine production GO:2000551 3 0.013
response to light stimulus GO:0009416 135 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
entry into host cell GO:0030260 15 0.013
serotonin uptake GO:0051610 3 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
protein maturation GO:0051604 176 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
response to mineralocorticoid GO:0051385 1 0.013
positive regulation of dopamine secretion GO:0033603 2 0.013
negative regulation of cytokine production GO:0001818 84 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
wound healing GO:0042060 157 0.012
divalent metal ion transport GO:0070838 172 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
cell division GO:0051301 120 0.012
carnitine transmembrane transport GO:1902603 3 0.012
amino acid transport GO:0006865 61 0.012
negative regulation of glycoprotein metabolic process GO:1903019 3 0.012
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.012
respiratory system development GO:0060541 190 0.012
defense response to virus GO:0051607 68 0.012
organic anion transport GO:0015711 137 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
aromatic compound catabolic process GO:0019439 286 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
negative regulation of adenylate cyclase activity GO:0007194 1 0.012
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.012
cellular protein catabolic process GO:0044257 155 0.012
trachea cartilage morphogenesis GO:0060535 4 0.012
transepithelial chloride transport GO:0030321 4 0.011
striated muscle tissue development GO:0014706 293 0.011
taurine transport GO:0015734 1 0.011
stat protein import into nucleus GO:0007262 6 0.011
oviduct development GO:0060066 3 0.011
sensory perception GO:0007600 245 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
regulation of sterol transport GO:0032371 17 0.011
cellular response to lipid GO:0071396 145 0.011
lens development in camera type eye GO:0002088 62 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
diencephalon development GO:0021536 63 0.011
protein ubiquitination GO:0016567 171 0.011
response to corticosterone GO:0051412 1 0.011
regulation of protein localization GO:0032880 231 0.011
homeostasis of number of cells GO:0048872 210 0.011
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.011
negative regulation of response to wounding GO:1903035 77 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
nuclear import GO:0051170 95 0.011
lipid transport GO:0006869 98 0.011
regulation of binding GO:0051098 111 0.011
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.011
blastocyst development GO:0001824 80 0.011
binding of sperm to zona pellucida GO:0007339 34 0.010
regulation of cellular amino acid metabolic process GO:0006521 5 0.010
monoamine transport GO:0015844 33 0.010
catecholamine uptake GO:0090493 4 0.010
nucleobase containing small molecule metabolic process GO:0055086 352 0.010
endomembrane system organization GO:0010256 147 0.010
neutral amino acid transport GO:0015804 13 0.010
lipid localization GO:0010876 126 0.010
sulfur compound transport GO:0072348 9 0.010
insulin like growth factor receptor signaling pathway GO:0048009 21 0.010
memory GO:0007613 58 0.010
inflammatory response GO:0006954 244 0.010
sodium ion transport GO:0006814 73 0.010
small molecule biosynthetic process GO:0044283 132 0.010
transmission of nerve impulse GO:0019226 76 0.010

Defb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
bone disease DOID:0080001 0 0.016
nervous system disease DOID:863 0 0.015