Mus musculus

27 known processes

Dennd1a

DENN/MADD domain containing 1A

(Aliases: 6030446I19Rik,MGC38995,connecdenn)

Dennd1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
guanosine containing compound metabolic process GO:1901068 144 0.189
Human
purine ribonucleotide metabolic process GO:0009150 290 0.188
Human
organonitrogen compound catabolic process GO:1901565 264 0.182
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.175
Human
small gtpase mediated signal transduction GO:0007264 97 0.142
Human
ras protein signal transduction GO:0007265 77 0.133
Human
purine nucleoside catabolic process GO:0006152 205 0.129
Human
aromatic compound catabolic process GO:0019439 286 0.124
Human
regulation of nucleoside metabolic process GO:0009118 130 0.122
Human
gtp metabolic process GO:0046039 144 0.119
Human
nucleotide metabolic process GO:0009117 332 0.115
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.111
Human
ribonucleotide metabolic process GO:0009259 291 0.102
Human
membrane organization GO:0061024 245 0.100
positive regulation of ras gtpase activity GO:0032320 65 0.099
Human
guanosine containing compound catabolic process GO:1901069 144 0.099
Human
positive regulation of gtp catabolic process GO:0033126 85 0.096
Human
nucleoside triphosphate metabolic process GO:0009141 230 0.094
Human
purine containing compound metabolic process GO:0072521 311 0.089
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.087
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.086
Human
regulation of gtp catabolic process GO:0033124 113 0.085
Human
purine nucleotide metabolic process GO:0006163 302 0.084
Human
purine nucleoside metabolic process GO:0042278 241 0.080
Human
ribose phosphate metabolic process GO:0019693 291 0.080
Human
organophosphate catabolic process GO:0046434 232 0.080
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.076
Human
nucleotide catabolic process GO:0009166 217 0.075
Human
purine ribonucleotide catabolic process GO:0009154 208 0.070
Human
purine ribonucleoside metabolic process GO:0046128 241 0.069
Human
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.068
Human
regulation of cell cycle process GO:0010564 160 0.065
nucleoside phosphate catabolic process GO:1901292 222 0.063
Human
rho protein signal transduction GO:0007266 32 0.063
regulation of ras protein signal transduction GO:0046578 114 0.062
Human
purine containing compound catabolic process GO:0072523 213 0.062
Human
positive regulation of nucleoside metabolic process GO:0045979 91 0.060
Human
regulation of ras gtpase activity GO:0032318 88 0.059
Human
regulation of purine nucleotide metabolic process GO:1900542 169 0.059
Human
organic cyclic compound catabolic process GO:1901361 295 0.056
Human
gtp catabolic process GO:0006184 143 0.056
Human
endomembrane system organization GO:0010256 147 0.056
nucleoside metabolic process GO:0009116 246 0.055
Human
regulation of cell cycle GO:0051726 281 0.053
ribonucleotide catabolic process GO:0009261 208 0.051
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
Human
nucleoside phosphate metabolic process GO:0006753 338 0.050
Human
ribonucleoside catabolic process GO:0042454 206 0.049
Human
cellular lipid metabolic process GO:0044255 323 0.048
regulation of cellular catabolic process GO:0031329 242 0.047
Human
glycosyl compound metabolic process GO:1901657 246 0.044
Human
regulation of nucleotide catabolic process GO:0030811 122 0.044
Human
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.044
Human
apoptotic signaling pathway GO:0097190 306 0.041
neuron death GO:0070997 154 0.040
carbohydrate derivative catabolic process GO:1901136 231 0.039
Human
neural precursor cell proliferation GO:0061351 121 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.038
positive regulation of programmed cell death GO:0043068 218 0.037
regulation of neuron death GO:1901214 134 0.036
peptidyl amino acid modification GO:0018193 336 0.036
regulation of neural precursor cell proliferation GO:2000177 70 0.035
regulation of neuron differentiation GO:0045664 281 0.035
cellular macromolecule catabolic process GO:0044265 206 0.034
endocytosis GO:0006897 168 0.034
negative regulation of intracellular signal transduction GO:1902532 167 0.034
cell type specific apoptotic process GO:0097285 268 0.034
glycosyl compound catabolic process GO:1901658 206 0.033
Human
carbohydrate metabolic process GO:0005975 230 0.033
regulation of vesicle mediated transport GO:0060627 139 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
regulation of organelle organization GO:0033043 289 0.033
dna metabolic process GO:0006259 303 0.033
positive regulation of apoptotic process GO:0043065 217 0.032
regulation of nucleotide metabolic process GO:0006140 169 0.032
Human
heterocycle catabolic process GO:0046700 280 0.031
Human
positive regulation of cell death GO:0010942 224 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
establishment of vesicle localization GO:0051650 81 0.030
vesicle organization GO:0016050 60 0.029
cellular amine metabolic process GO:0044106 44 0.029
protein ubiquitination GO:0016567 171 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
notch signaling pathway GO:0007219 71 0.028
positive regulation of cell development GO:0010720 237 0.028
cellular ketone metabolic process GO:0042180 84 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
dephosphorylation GO:0016311 129 0.028
plasma membrane organization GO:0007009 90 0.027
male gamete generation GO:0048232 285 0.027
regulation of rho protein signal transduction GO:0035023 71 0.027
regulation of stem cell proliferation GO:0072091 78 0.027
regulation of rho gtpase activity GO:0032319 58 0.027
covalent chromatin modification GO:0016569 163 0.027
phosphatidic acid biosynthetic process GO:0006654 2 0.026
regulation of cell projection organization GO:0031344 206 0.026
compound eye development GO:0048749 1 0.026
stem cell proliferation GO:0072089 117 0.026
glycerophospholipid metabolic process GO:0006650 71 0.026
positive regulation of protein kinase activity GO:0045860 144 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
protein catabolic process GO:0030163 221 0.026
lipid biosynthetic process GO:0008610 179 0.025
protein localization to organelle GO:0033365 185 0.025
anatomical structure homeostasis GO:0060249 145 0.025
regulation of endocytosis GO:0030100 69 0.024
regulation of neuron apoptotic process GO:0043523 122 0.024
neuron apoptotic process GO:0051402 142 0.024
positive regulation of protein modification process GO:0031401 299 0.024
amine metabolic process GO:0009308 45 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
epithelial tube formation GO:0072175 130 0.024
forebrain development GO:0030900 302 0.023
response to endoplasmic reticulum stress GO:0034976 53 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
mitotic cell cycle GO:0000278 195 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
cellular protein catabolic process GO:0044257 155 0.022
establishment of organelle localization GO:0051656 122 0.022
cytoplasmic transport GO:0016482 234 0.022
synaptic vesicle transport GO:0048489 57 0.022
golgi to endosome transport GO:0006895 3 0.022
tube formation GO:0035148 140 0.022
sensory perception GO:0007600 245 0.022
positive regulation of rho gtpase activity GO:0032321 41 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.021
Human
negative regulation of cell development GO:0010721 169 0.021
phagosome maturation GO:0090382 4 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
transmembrane transport GO:0055085 412 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
Human
anion transport GO:0006820 177 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
regulation of cell division GO:0051302 76 0.021
nitrogen compound transport GO:0071705 271 0.021
cell division GO:0051301 120 0.020
locomotory behavior GO:0007626 195 0.020
oxidation reduction process GO:0055114 342 0.020
vesicle localization GO:0051648 86 0.020
regulation of transferase activity GO:0051338 263 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
cellular homeostasis GO:0019725 240 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
gland development GO:0048732 330 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
Human
cellular protein complex assembly GO:0043623 116 0.019
negative regulation of neuron death GO:1901215 98 0.019
organelle localization GO:0051640 179 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
organelle fission GO:0048285 170 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regionalization GO:0003002 337 0.019
regulation of membrane potential GO:0042391 192 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
synaptic transmission GO:0007268 329 0.018
chromatin modification GO:0016568 187 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
positive regulation of organelle organization GO:0010638 128 0.018
vacuole organization GO:0007033 38 0.018
synaptic vesicle localization GO:0097479 59 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
regulation of mapk cascade GO:0043408 248 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
response to nutrient levels GO:0031667 109 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
macromolecule catabolic process GO:0009057 281 0.017
protein localization to membrane GO:0072657 108 0.017
neural tube formation GO:0001841 108 0.017
organic anion transport GO:0015711 137 0.017
protein maturation GO:0051604 176 0.017
adult locomotory behavior GO:0008344 91 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
response to oxidative stress GO:0006979 123 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
positive regulation of gtpase activity GO:0043547 85 0.017
Human
carboxylic acid biosynthetic process GO:0046394 86 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
Human
membrane tubulation GO:0097320 4 0.017
synaptic vesicle membrane organization GO:0048499 1 0.017
positive regulation of cell cycle process GO:0090068 61 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
Human
clathrin mediated endocytosis GO:0072583 7 0.017
small molecule biosynthetic process GO:0044283 132 0.016
positive regulation of transferase activity GO:0051347 167 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
primary neural tube formation GO:0014020 95 0.016
positive regulation of cell cycle GO:0045787 92 0.016
positive regulation of dna templated transcription elongation GO:0032786 2 0.016
monosaccharide metabolic process GO:0005996 106 0.016
renal system development GO:0072001 225 0.016
tube closure GO:0060606 91 0.016
positive regulation of nervous system development GO:0051962 221 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
regulation of cell migration GO:0030334 219 0.015
wnt signaling pathway GO:0016055 188 0.015
regulation of proteolysis GO:0030162 164 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
mitotic cytokinesis GO:0000281 4 0.015
positive regulation of necrotic cell death GO:0010940 1 0.015
protein processing GO:0016485 163 0.015
cell junction organization GO:0034330 77 0.015
response to extracellular stimulus GO:0009991 127 0.015
organic hydroxy compound transport GO:0015850 93 0.015
skeletal system development GO:0001501 356 0.015
protein glycosylation GO:0006486 55 0.014
establishment of synaptic vesicle localization GO:0097480 57 0.014
hindbrain development GO:0030902 128 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
regulation of protein complex assembly GO:0043254 83 0.014
positive regulation of cell division GO:0051781 31 0.014
response to organonitrogen compound GO:0010243 246 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
microtubule based process GO:0007017 236 0.014
lung development GO:0030324 164 0.014
t cell activation GO:0042110 289 0.014
glycoprotein metabolic process GO:0009100 116 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
cellularization GO:0007349 1 0.014
mitochondrion organization GO:0007005 134 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
regulation of hydrolase activity GO:0051336 246 0.014
Human
intracellular protein transport GO:0006886 204 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
positive regulation of stem cell proliferation GO:2000648 59 0.014
regulation of secretion GO:0051046 274 0.014
cation transport GO:0006812 399 0.014
maintenance of location GO:0051235 89 0.013
synaptic vesicle endocytosis GO:0048488 19 0.013
cation transmembrane transport GO:0098655 266 0.013
regulation of cell motility GO:2000145 236 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
striated muscle tissue development GO:0014706 293 0.013
memory GO:0007613 58 0.013
cerebellum development GO:0021549 77 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
organelle assembly GO:0070925 177 0.013
regulation of intracellular transport GO:0032386 159 0.013
anion transmembrane transport GO:0098656 71 0.013
response to oxygen levels GO:0070482 62 0.013
regulation of kinase activity GO:0043549 249 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
regulation of translation GO:0006417 71 0.013
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 6 0.013
transmission of nerve impulse GO:0019226 76 0.013
camera type eye development GO:0043010 266 0.013
positive regulation of kinase activity GO:0033674 155 0.012
appendage development GO:0048736 166 0.012
response to lipopolysaccharide GO:0032496 128 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
actin filament polymerization GO:0030041 44 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
neuromuscular process GO:0050905 99 0.012
cell adhesion GO:0007155 329 0.012
skin development GO:0043588 220 0.012
glycerolipid metabolic process GO:0046486 122 0.012
immune effector process GO:0002252 321 0.012
positive regulation of protein kinase b signaling GO:0051897 32 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
regulation of secretion by cell GO:1903530 249 0.012
response to topologically incorrect protein GO:0035966 25 0.012
cell substrate adhesion GO:0031589 130 0.012
fertilization GO:0009566 127 0.012
organic acid biosynthetic process GO:0016053 86 0.012
response to peptide GO:1901652 136 0.012
regulation of cell activation GO:0050865 289 0.012
sensory organ morphogenesis GO:0090596 242 0.012
cellular chemical homeostasis GO:0055082 215 0.012
organic acid transport GO:0015849 101 0.012
hindbrain morphogenesis GO:0021575 46 0.012
phospholipid biosynthetic process GO:0008654 36 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
lysosome organization GO:0007040 21 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
Human
regulation of clathrin mediated endocytosis GO:2000369 4 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
Human
nucleoside catabolic process GO:0009164 206 0.012
Human
neural tube closure GO:0001843 90 0.012
cellular response to topologically incorrect protein GO:0035967 25 0.012
muscle cell differentiation GO:0042692 261 0.012
homeostasis of number of cells GO:0048872 210 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
regulation of cell adhesion GO:0030155 154 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
skeletal system morphogenesis GO:0048705 203 0.011
synaptic vesicle recycling GO:0036465 19 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
carboxylic acid transport GO:0046942 100 0.011
cerebellum morphogenesis GO:0021587 42 0.011
negative regulation of immune system process GO:0002683 209 0.011
membrane fusion GO:0061025 38 0.011
positive regulation of rac gtpase activity GO:0032855 14 0.011
rhythmic process GO:0048511 174 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
negative regulation of nervous system development GO:0051961 156 0.011
phospholipid metabolic process GO:0006644 87 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
Human
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
nuclear division GO:0000280 158 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
b cell activation GO:0042113 161 0.011
er nucleus signaling pathway GO:0006984 27 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
chromatin organization GO:0006325 206 0.011
protein acylation GO:0043543 64 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of cellular response to stress GO:0080135 159 0.011
meiotic nuclear division GO:0007126 115 0.011
regulation of protein kinase activity GO:0045859 232 0.011
sequestering of metal ion GO:0051238 19 0.011
regulation of binding GO:0051098 111 0.010
respiratory system development GO:0060541 190 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
clathrin coat assembly GO:0048268 2 0.010
beta amyloid clearance GO:0097242 2 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
lateral inhibition GO:0046331 1 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
sensory perception of sound GO:0007605 97 0.010
ion transmembrane transport GO:0034220 361 0.010
muscle tissue development GO:0060537 308 0.010
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.010
neural tube development GO:0021915 160 0.010
apical constriction GO:0003383 4 0.010
multicellular organism growth GO:0035264 161 0.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.010
regulation of response to drug GO:2001023 2 0.010
rab protein signal transduction GO:0032482 1 0.010
Human
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
mapk cascade GO:0000165 281 0.010
metencephalon development GO:0022037 89 0.010
tissue homeostasis GO:0001894 115 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
Human

Dennd1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.048
central nervous system disease DOID:331 0 0.030
eye and adnexa disease DOID:1492 0 0.017
sensory system disease DOID:0050155 0 0.017
disease of metabolism DOID:0014667 0 0.015
eye disease DOID:5614 0 0.012
immune system disease DOID:2914 0 0.011
musculoskeletal system disease DOID:17 0 0.011
neurodegenerative disease DOID:1289 0 0.011
neuromuscular disease DOID:440 0 0.010
neuropathy DOID:870 0 0.010