Mus musculus

0 known processes

Depdc1a

DEP domain containing 1a

(Aliases: 5830484J08Rik,Depdc1)

Depdc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 206 0.345
ubiquitin dependent protein catabolic process GO:0006511 129 0.293
sister chromatid segregation GO:0000819 20 0.293
cellular protein catabolic process GO:0044257 155 0.279
regulation of microtubule based process GO:0032886 52 0.249
regulation of spindle organization GO:0090224 2 0.173
regulation of chromosome segregation GO:0051983 21 0.167
regulation of cellular catabolic process GO:0031329 242 0.155
attachment of spindle microtubules to kinetochore GO:0008608 4 0.152
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.148
regulation of cytoskeleton organization GO:0051493 122 0.138
dna metabolic process GO:0006259 303 0.132
chromosome separation GO:0051304 14 0.131
regulation of microtubule cytoskeleton organization GO:0070507 37 0.099
microtubule polymerization or depolymerization GO:0031109 26 0.097
negative regulation of cellular component organization GO:0051129 194 0.096
regulation of cell cycle GO:0051726 281 0.093
macromolecule catabolic process GO:0009057 281 0.089
organelle fission GO:0048285 170 0.086
mitotic cell cycle GO:0000278 195 0.083
regulation of protein maturation GO:1903317 96 0.082
modification dependent protein catabolic process GO:0019941 133 0.080
cellular protein complex disassembly GO:0043624 36 0.079
microtubule cytoskeleton organization GO:0000226 157 0.079
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.075
regulation of cellular protein catabolic process GO:1903362 61 0.074
protein catabolic process GO:0030163 221 0.073
regulation of organelle organization GO:0033043 289 0.069
mitotic sister chromatid segregation GO:0000070 14 0.069
spindle assembly involved in mitosis GO:0090307 4 0.068
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.067
activation of rac gtpase activity GO:0032863 2 0.066
negative regulation of protein maturation GO:1903318 79 0.066
mitotic cell cycle process GO:1903047 159 0.065
cytokinetic process GO:0032506 2 0.065
nuclear division GO:0000280 158 0.063
proteasomal protein catabolic process GO:0010498 98 0.063
negative regulation of protein complex disassembly GO:0043242 22 0.062
protein complex disassembly GO:0043241 40 0.060
negative regulation of proteolysis GO:0045861 74 0.059
regulation of protein complex disassembly GO:0043244 28 0.058
regulation of sister chromatid segregation GO:0033045 13 0.058
regulation of proteasomal protein catabolic process GO:0061136 46 0.057
aromatic compound catabolic process GO:0019439 286 0.056
positive regulation of apoptotic process GO:0043065 217 0.055
modification dependent macromolecule catabolic process GO:0043632 133 0.053
meiotic cell cycle GO:0051321 122 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.051
maintenance of location GO:0051235 89 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.050
negative regulation of cell cycle GO:0045786 123 0.049
microtubule based process GO:0007017 236 0.049
protein processing GO:0016485 163 0.047
response to radiation GO:0009314 165 0.045
regulation of cell cycle process GO:0010564 160 0.044
cellular ketone metabolic process GO:0042180 84 0.043
nucleotide metabolic process GO:0009117 332 0.043
protein maturation GO:0051604 176 0.042
regulation of proteolysis GO:0030162 164 0.041
male gamete generation GO:0048232 285 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
purine nucleoside metabolic process GO:0042278 241 0.040
rho protein signal transduction GO:0007266 32 0.040
mitotic cytokinesis GO:0000281 4 0.039
negative regulation of protein metabolic process GO:0051248 282 0.039
regulation of protein depolymerization GO:1901879 26 0.039
cellular amine metabolic process GO:0044106 44 0.038
male meiosis GO:0007140 37 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
hematopoietic progenitor cell differentiation GO:0002244 143 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.035
amine metabolic process GO:0009308 45 0.035
negative regulation of cytoskeleton organization GO:0051494 36 0.035
positive regulation of cellular catabolic process GO:0031331 148 0.034
chromosome segregation GO:0007059 48 0.034
positive regulation of protein modification process GO:0031401 299 0.034
ribose phosphate metabolic process GO:0019693 291 0.033
spermatogenesis GO:0007283 284 0.033
protein depolymerization GO:0051261 34 0.033
mitotic spindle checkpoint GO:0071174 9 0.032
oxidation reduction process GO:0055114 342 0.032
macromolecular complex disassembly GO:0032984 43 0.032
regulation of transferase activity GO:0051338 263 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
mitotic nuclear division GO:0007067 48 0.031
regulation of protein kinase activity GO:0045859 232 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
regulation of chromosome organization GO:0033044 83 0.031
cellular amino acid metabolic process GO:0006520 103 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.030
mitotic sister chromatid separation GO:0051306 9 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.030
negative regulation of cellular protein catabolic process GO:1903363 22 0.030
myeloid cell differentiation GO:0030099 233 0.029
maintenance of protein location in cell GO:0032507 20 0.029
regulation of protein localization GO:0032880 231 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
regulation of kinase activity GO:0043549 249 0.028
wnt signaling pathway GO:0016055 188 0.028
apoptotic signaling pathway GO:0097190 306 0.028
ribonucleoside catabolic process GO:0042454 206 0.027
regulation of protein catabolic process GO:0042176 108 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
organelle assembly GO:0070925 177 0.027
negative regulation of cellular catabolic process GO:0031330 47 0.027
regulation of hydrolase activity GO:0051336 246 0.026
positive regulation of kinase activity GO:0033674 155 0.026
negative regulation of molecular function GO:0044092 258 0.026
cellular response to lipid GO:0071396 145 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
cellular response to dna damage stimulus GO:0006974 207 0.025
mesodermal cell migration GO:0008078 4 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
chromatin modification GO:0016568 187 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.025
cell fate commitment GO:0045165 210 0.025
nucleoside catabolic process GO:0009164 206 0.025
neural precursor cell proliferation GO:0061351 121 0.024
purine containing compound metabolic process GO:0072521 311 0.024
gtp metabolic process GO:0046039 144 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
centrosome separation GO:0051299 4 0.024
covalent chromatin modification GO:0016569 163 0.024
nucleoside metabolic process GO:0009116 246 0.024
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.024
cdc42 protein signal transduction GO:0032488 0 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.023
heterocycle catabolic process GO:0046700 280 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
intrinsic apoptotic signaling pathway GO:0097193 132 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
ras protein signal transduction GO:0007265 77 0.023
response to organic cyclic compound GO:0014070 198 0.023
endocytosis GO:0006897 168 0.023
regulation of mitotic cell cycle phase transition GO:1901990 73 0.023
protein ubiquitination GO:0016567 171 0.022
positive regulation of cell death GO:0010942 224 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
germ cell development GO:0007281 185 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
cell division GO:0051301 120 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
leukocyte differentiation GO:0002521 342 0.022
nucleotide catabolic process GO:0009166 217 0.021
negative regulation of organelle organization GO:0010639 90 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
microtubule anchoring GO:0034453 9 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
inflammatory response GO:0006954 244 0.021
negative regulation of protein catabolic process GO:0042177 36 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
regulation of rho gtpase activity GO:0032319 58 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
regulation of protein processing GO:0070613 96 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
muscle tissue development GO:0060537 308 0.019
response to reactive oxygen species GO:0000302 56 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
positive regulation of transferase activity GO:0051347 167 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.018
rac protein signal transduction GO:0016601 13 0.018
microtubule depolymerization GO:0007019 15 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
protein polymerization GO:0051258 57 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of neuron differentiation GO:0045664 281 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
regulation of actin filament based process GO:0032970 99 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
negative regulation of cell division GO:0051782 24 0.018
protein localization to organelle GO:0033365 185 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
homeostasis of number of cells GO:0048872 210 0.017
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.017
microtubule based movement GO:0007018 84 0.017
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
gonad development GO:0008406 141 0.017
response to oxidative stress GO:0006979 123 0.017
actin cytoskeleton organization GO:0030036 220 0.017
regulation of intracellular transport GO:0032386 159 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
cell adhesion GO:0007155 329 0.017
positive regulation of cell development GO:0010720 237 0.017
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
lymphocyte differentiation GO:0030098 242 0.017
regulation of cell division GO:0051302 76 0.017
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.016
cell type specific apoptotic process GO:0097285 268 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
cytokinesis GO:0000910 17 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
positive regulation of cell division GO:0051781 31 0.016
negative regulation of phagocytosis GO:0050765 4 0.016
regulation of cell projection organization GO:0031344 206 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.016
protein oligomerization GO:0051259 67 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
negative regulation of protein processing GO:0010955 79 0.015
meiosis ii GO:0007135 7 0.015
female meiosis chromosome segregation GO:0016321 1 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of cell activation GO:0050865 289 0.015
blood vessel morphogenesis GO:0048514 285 0.015
negative regulation of protein modification process GO:0031400 163 0.015
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.015
centromere complex assembly GO:0034508 3 0.015
cellular homeostasis GO:0019725 240 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
cellular protein complex assembly GO:0043623 116 0.015
myeloid cell homeostasis GO:0002262 114 0.015
carbohydrate homeostasis GO:0033500 128 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
asymmetric stem cell division GO:0098722 3 0.015
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.014
positive regulation of chromosome segregation GO:0051984 4 0.014
cellular response to oxidative stress GO:0034599 76 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
ameboidal type cell migration GO:0001667 128 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
striated muscle tissue development GO:0014706 293 0.014
cation transport GO:0006812 399 0.014
positive regulation of cell cycle process GO:0090068 61 0.014
cellular response to inorganic substance GO:0071241 37 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
regulation of neuron projection development GO:0010975 169 0.014
positive regulation of cell cycle GO:0045787 92 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
cellular lipid metabolic process GO:0044255 323 0.013
maintenance of location in cell GO:0051651 24 0.013
regulation of homeostatic process GO:0032844 182 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
leukocyte mediated immunity GO:0002443 174 0.013
positive regulation of nervous system development GO:0051962 221 0.013
negative regulation of wnt signaling pathway GO:0030178 73 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
spindle checkpoint GO:0031577 12 0.013
placenta development GO:0001890 140 0.013
immune effector process GO:0002252 321 0.013
axonogenesis GO:0007409 274 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
muscle cell differentiation GO:0042692 261 0.012
striated muscle cell development GO:0055002 125 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
transmission of nerve impulse GO:0019226 76 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
regulation of cellular response to stress GO:0080135 159 0.012
mitotic spindle organization GO:0007052 10 0.012
circulatory system process GO:0003013 197 0.012
erythrocyte differentiation GO:0030218 88 0.012
purine containing compound catabolic process GO:0072523 213 0.012
protein homooligomerization GO:0051260 43 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
respiratory system development GO:0060541 190 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
anion transport GO:0006820 177 0.012
regulation of system process GO:0044057 200 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
positive regulation of cytoplasmic transport GO:1903651 40 0.012
myotube differentiation GO:0014902 105 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
response to growth factor GO:0070848 198 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
formation of primary germ layer GO:0001704 77 0.011
neural tube development GO:0021915 160 0.011
negative regulation of chromosome organization GO:2001251 30 0.011
neural tube formation GO:0001841 108 0.011
regulation of mitosis GO:0007088 29 0.011
peptidyl amino acid modification GO:0018193 336 0.011
multicellular organismal signaling GO:0035637 91 0.011
cell recognition GO:0008037 83 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
regulation of canonical wnt signaling pathway GO:0060828 82 0.011
methylation GO:0032259 134 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of response to wounding GO:1903034 189 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
cell junction assembly GO:0034329 52 0.011
response to organonitrogen compound GO:0010243 246 0.011
organ growth GO:0035265 117 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
tube formation GO:0035148 140 0.011
dna endoreduplication GO:0042023 4 0.011
regulation of muscle tissue development GO:1901861 97 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
positive regulation of rho gtpase activity GO:0032321 41 0.011
glucose homeostasis GO:0042593 128 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
sensory perception GO:0007600 245 0.010
microtubule organizing center organization GO:0031023 28 0.010
negative regulation of sister chromatid segregation GO:0033046 7 0.010
regulation of neural precursor cell proliferation GO:2000177 70 0.010
organophosphate catabolic process GO:0046434 232 0.010
mrna metabolic process GO:0016071 84 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
lung development GO:0030324 164 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
lipid biosynthetic process GO:0008610 179 0.010
regulation of protein targeting GO:1903533 61 0.010
hexose metabolic process GO:0019318 98 0.010
cellular chemical homeostasis GO:0055082 215 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
negative regulation of cell cycle phase transition GO:1901988 48 0.010
regulation of protein complex assembly GO:0043254 83 0.010
dna ligation GO:0006266 3 0.010
cell migration involved in gastrulation GO:0042074 13 0.010

Depdc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.033
cancer DOID:162 0 0.024
thoracic cancer DOID:5093 0 0.014
organ system cancer DOID:0050686 0 0.014
breast cancer DOID:1612 0 0.014