Mus musculus

107 known processes

Dhx58

DEXH (Asp-Glu-X-His) box polypeptide 58

(Aliases: D11Lgp2e,B430001I08Rik,Lgp2,LPG2)

Dhx58 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 10 0.995
viral process GO:0016032 41 0.985
Mouse
interspecies interaction between organisms GO:0044419 83 0.961
Mouse
viral genome replication GO:0019079 17 0.873
Mouse
toll like receptor 7 signaling pathway GO:0034154 4 0.769
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.734
Mouse
negative regulation of multi organism process GO:0043901 68 0.687
regulation of innate immune response GO:0045088 91 0.638
regulation of viral genome replication GO:0045069 13 0.623
Mouse
positive regulation of defense response GO:0031349 124 0.587
immune response regulating signaling pathway GO:0002764 125 0.552
defense response to other organism GO:0098542 197 0.510
activation of innate immune response GO:0002218 56 0.492
positive regulation of innate immune response GO:0045089 80 0.476
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.474
Mouse
negative regulation of viral process GO:0048525 23 0.390
defense response to virus GO:0051607 68 0.374
toll like receptor 9 signaling pathway GO:0034162 6 0.352
pattern recognition receptor signaling pathway GO:0002221 47 0.347
response to type i interferon GO:0034340 12 0.329
innate immune response GO:0045087 157 0.286
regulation of interferon beta production GO:0032648 13 0.285
Mouse
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.275
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.258
viral life cycle GO:0019058 36 0.250
Mouse
regulation of multi organism process GO:0043900 111 0.230
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.212
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.212
negative regulation of immune effector process GO:0002698 55 0.206
myeloid cell differentiation GO:0030099 233 0.193
positive regulation of interferon alpha production GO:0032727 4 0.180
immune effector process GO:0002252 321 0.178
carbohydrate metabolic process GO:0005975 230 0.172
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.162
rig i signaling pathway GO:0039529 4 0.150
positive regulation of type i interferon production GO:0032481 14 0.139
type i interferon signaling pathway GO:0060337 10 0.132
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.125
activation of immune response GO:0002253 138 0.123
macromolecule catabolic process GO:0009057 281 0.117
response to dsrna GO:0043331 30 0.100
Mouse Worm
cellular response to organic cyclic compound GO:0071407 87 0.100
Mouse Worm
posttranscriptional regulation of gene expression GO:0010608 155 0.098
Mouse Worm
organonitrogen compound biosynthetic process GO:1901566 192 0.098
protein modification by small protein conjugation GO:0032446 187 0.096
rna catabolic process GO:0006401 29 0.092
regulation of type i interferon production GO:0032479 22 0.091
nucleotide biosynthetic process GO:0009165 78 0.090
organic cyclic compound catabolic process GO:1901361 295 0.088
Worm
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.084
toll like receptor signaling pathway GO:0002224 38 0.082
cellular response to interferon alpha GO:0035457 4 0.080
cellular response to lipid GO:0071396 145 0.079
positive regulation of response to cytokine stimulus GO:0060760 11 0.079
regulation of cellular ketone metabolic process GO:0010565 66 0.078
regulation of cell activation GO:0050865 289 0.075
intracellular protein transport GO:0006886 204 0.074
antigen processing and presentation GO:0019882 47 0.071
cellular macromolecule catabolic process GO:0044265 206 0.068
positive regulation of immune effector process GO:0002699 107 0.067
regulation of response to biotic stimulus GO:0002831 38 0.067
dna metabolic process GO:0006259 303 0.066
cellular nitrogen compound catabolic process GO:0044270 280 0.066
Worm
regulation of cellular amine metabolic process GO:0033238 20 0.065
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.062
interferon beta production GO:0032608 16 0.061
Mouse
immune response activating signal transduction GO:0002757 116 0.060
response to organic cyclic compound GO:0014070 198 0.060
Mouse Worm
protein import into nucleus GO:0006606 95 0.060
antigen processing and presentation of exogenous antigen GO:0019884 26 0.059
regulation of defense response to virus by host GO:0050691 8 0.058
purine containing compound metabolic process GO:0072521 311 0.057
Worm
nucleoside phosphate biosynthetic process GO:1901293 79 0.056
cytokine biosynthetic process GO:0042089 68 0.055
chromatin organization GO:0006325 206 0.055
regulation of defense response to virus GO:0050688 18 0.054
regulation of antimicrobial humoral response GO:0002759 3 0.054
regulation of interferon beta biosynthetic process GO:0045357 4 0.053
cellular response to cytokine stimulus GO:0071345 189 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.053
Worm
stem cell differentiation GO:0048863 268 0.052
Mouse
regulation of defense response GO:0031347 233 0.051
positive regulation of viral genome replication GO:0045070 2 0.051
viral transcription GO:0019083 3 0.050
cellular lipid metabolic process GO:0044255 323 0.050
t cell activation GO:0042110 289 0.048
positive regulation of actin nucleation GO:0051127 3 0.048
protein acylation GO:0043543 64 0.047
neuronal action potential GO:0019228 54 0.047
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.046
protein modification by small protein conjugation or removal GO:0070647 207 0.046
cellular protein catabolic process GO:0044257 155 0.045
negative regulation of cytokine production GO:0001818 84 0.045
cellular response to dna damage stimulus GO:0006974 207 0.045
Worm
cytoplasmic transport GO:0016482 234 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.044
cellular amine metabolic process GO:0044106 44 0.043
modification dependent macromolecule catabolic process GO:0043632 133 0.043
ear development GO:0043583 200 0.043
Mouse
interleukin 6 production GO:0032635 58 0.043
histone modification GO:0016570 159 0.042
modification dependent protein catabolic process GO:0019941 133 0.042
reactive oxygen species metabolic process GO:0072593 84 0.042
intracellular receptor signaling pathway GO:0030522 74 0.041
methylation GO:0032259 134 0.039
regulation of cell cycle GO:0051726 281 0.038
Mouse
regulation of viral transcription GO:0046782 3 0.038
organelle assembly GO:0070925 177 0.038
Mouse
erythrocyte differentiation GO:0030218 88 0.038
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.037
aromatic compound catabolic process GO:0019439 286 0.037
Worm
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.036
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.036
spermatogenesis GO:0007283 284 0.036
positive regulation of viral entry into host cell GO:0046598 3 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
glycosylation GO:0070085 62 0.035
viral gene expression GO:0019080 3 0.035
positive regulation of cytokine production GO:0001819 174 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
regulation of leukocyte mediated immunity GO:0002703 104 0.034
regulation of actin nucleation GO:0051125 4 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
Worm
organophosphate biosynthetic process GO:0090407 122 0.033
negative regulation of protein metabolic process GO:0051248 282 0.033
peptidyl amino acid modification GO:0018193 336 0.033
purine ribonucleoside catabolic process GO:0046130 205 0.032
Worm
regulation of organelle organization GO:0033043 289 0.032
myeloid dendritic cell differentiation GO:0043011 16 0.032
multicellular organismal homeostasis GO:0048871 164 0.031
negative regulation of nervous system development GO:0051961 156 0.031
Mouse
regulation of response to cytokine stimulus GO:0060759 23 0.031
cellular chemical homeostasis GO:0055082 215 0.031
nucleocytoplasmic transport GO:0006913 139 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
Worm
regulation of membrane potential GO:0042391 192 0.030
cytokine mediated signaling pathway GO:0019221 115 0.029
antimicrobial peptide production GO:0002775 2 0.029
peptidyl lysine methylation GO:0018022 29 0.029
cellular response to biotic stimulus GO:0071216 92 0.028
cellular ketone metabolic process GO:0042180 84 0.028
negative regulation of defense response to virus GO:0050687 6 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
positive regulation of protein modification process GO:0031401 299 0.028
positive regulation of interleukin 8 production GO:0032757 2 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
protein polyubiquitination GO:0000209 33 0.027
regulation of tumor necrosis factor production GO:0032680 49 0.027
purine nucleoside monophosphate metabolic process GO:0009126 81 0.027
Worm
regulation of toll like receptor signaling pathway GO:0034121 20 0.027
cellular response to type i interferon GO:0071357 10 0.026
cytokine metabolic process GO:0042107 71 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
lipid localization GO:0010876 126 0.026
positive regulation of kinase activity GO:0033674 155 0.026
heterocycle catabolic process GO:0046700 280 0.026
Worm
regulation of protein transport GO:0051223 163 0.025
anatomical structure homeostasis GO:0060249 145 0.025
wound healing GO:0042060 157 0.025
Mouse
epithelial cell proliferation GO:0050673 174 0.025
response to radiation GO:0009314 165 0.025
interleukin 8 production GO:0032637 4 0.025
protein catabolic process GO:0030163 221 0.025
ribonucleoside catabolic process GO:0042454 206 0.024
Worm
regulation of interleukin 8 production GO:0032677 3 0.024
protein ubiquitination GO:0016567 171 0.024
protein methylation GO:0006479 81 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
Worm
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
purine nucleotide biosynthetic process GO:0006164 65 0.024
positive regulation of intracellular transport GO:0032388 70 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
sequestering of metal ion GO:0051238 19 0.023
purine containing compound catabolic process GO:0072523 213 0.023
Worm
glycoprotein biosynthetic process GO:0009101 89 0.023
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.023
defense response to bacterium GO:0042742 119 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
Worm
macromolecule methylation GO:0043414 120 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
lymphocyte proliferation GO:0046651 164 0.022
negative regulation of immune system process GO:0002683 209 0.022
homeostasis of number of cells GO:0048872 210 0.022
ubiquitin dependent protein catabolic process GO:0006511 129 0.022
negative regulation of interferon beta production GO:0032688 3 0.022
male gamete generation GO:0048232 285 0.021
digestive system development GO:0055123 200 0.021
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.021
regulation of proteolysis GO:0030162 164 0.021
protein import GO:0017038 101 0.020
protein glycosylation GO:0006486 55 0.020
cell activation involved in immune response GO:0002263 126 0.020
maintenance of location GO:0051235 89 0.020
positive regulation of jnk cascade GO:0046330 46 0.020
gland development GO:0048732 330 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
membrane organization GO:0061024 245 0.020
innate immune response activating signal transduction GO:0002758 50 0.020
atp metabolic process GO:0046034 75 0.020
Worm
regulation of cytokine biosynthetic process GO:0042035 59 0.020
nucleotide metabolic process GO:0009117 332 0.020
Worm
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
peptidyl lysine modification GO:0018205 77 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
divalent metal ion transport GO:0070838 172 0.020
myeloid cell homeostasis GO:0002262 114 0.020
regulation of interferon gamma production GO:0032649 57 0.019
positive regulation of adaptive immune response GO:0002821 61 0.019
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
mapk cascade GO:0000165 281 0.019
purine nucleoside monophosphate catabolic process GO:0009128 58 0.019
Worm
myeloid dendritic cell activation GO:0001773 25 0.019
positive regulation of protein localization to nucleus GO:1900182 30 0.019
regulation of nucleocytoplasmic transport GO:0046822 73 0.019
covalent chromatin modification GO:0016569 163 0.019
regulation of adaptive immune response GO:0002819 90 0.019
internal protein amino acid acetylation GO:0006475 42 0.019
microtubule based process GO:0007017 236 0.019
Mouse
regulation of interleukin 6 production GO:0032675 55 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
Worm
germ cell development GO:0007281 185 0.019
protein targeting GO:0006605 143 0.018
limb morphogenesis GO:0035108 149 0.018
Mouse
monosaccharide metabolic process GO:0005996 106 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
ion transmembrane transport GO:0034220 361 0.018
cation homeostasis GO:0055080 212 0.018
histone acetylation GO:0016573 41 0.018
positive regulation of cytokine biosynthetic process GO:0042108 40 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
lipoprotein metabolic process GO:0042157 43 0.018
transmembrane transport GO:0055085 412 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.018
connective tissue development GO:0061448 179 0.018
Mouse
dna recombination GO:0006310 92 0.018
posttranscriptional gene silencing GO:0016441 10 0.018
Mouse Worm
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
Worm
positive regulation of organelle organization GO:0010638 128 0.018
chromatin modification GO:0016568 187 0.018
tumor necrosis factor production GO:0032640 50 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
leukocyte mediated immunity GO:0002443 174 0.018
positive regulation of interferon beta production GO:0032728 8 0.017
Mouse
action potential GO:0001508 78 0.017
nitrogen compound transport GO:0071705 271 0.017
sequestering of calcium ion GO:0051208 18 0.017
fat cell differentiation GO:0045444 160 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
Mouse
regulation of cell migration GO:0030334 219 0.017
nuclear import GO:0051170 95 0.017
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.017
mitotic cell cycle GO:0000278 195 0.017
necrotic cell death GO:0070265 30 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.016
Worm
apoptotic signaling pathway GO:0097190 306 0.016
interaction with host GO:0051701 22 0.016
protein localization to nucleus GO:0034504 121 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
Worm
cation transport GO:0006812 399 0.016
protein localization to organelle GO:0033365 185 0.016
cellular component assembly involved in morphogenesis GO:0010927 139 0.016
Mouse
adaptive immune response GO:0002250 155 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
macromolecule glycosylation GO:0043413 55 0.016
regulation of neuron differentiation GO:0045664 281 0.016
Mouse
cytokine production GO:0001816 319 0.016
regulation of cellular response to stress GO:0080135 159 0.016
internal peptidyl lysine acetylation GO:0018393 42 0.016
compound eye development GO:0048749 1 0.016
glycoprotein metabolic process GO:0009100 116 0.016
positive regulation of transferase activity GO:0051347 167 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
telencephalon development GO:0021537 186 0.015
Mouse
regulation of intracellular protein transport GO:0033157 82 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
negative regulation of viral transcription GO:0032897 3 0.015
stem cell maintenance GO:0019827 130 0.015
Mouse
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.015
regulation of lymphocyte proliferation GO:0050670 117 0.015
cellular response to external stimulus GO:0071496 88 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
Worm
b cell activation GO:0042113 161 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
cell fate commitment GO:0045165 210 0.015
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.014
interferon beta biosynthetic process GO:0045350 4 0.014
nuclear transport GO:0051169 139 0.014
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.014
transmission of nerve impulse GO:0019226 76 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
negative regulation of defense response GO:0031348 77 0.014
cell division GO:0051301 120 0.014
Mouse
negative regulation of viral entry into host cell GO:0046597 10 0.014
stem cell development GO:0048864 219 0.014
Mouse
entry into other organism involved in symbiotic interaction GO:0051828 15 0.014
carbohydrate catabolic process GO:0016052 32 0.014
protein alkylation GO:0008213 81 0.014
cellular response to peptidoglycan GO:0071224 4 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
regulation of chemokine production GO:0032642 30 0.014
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
Worm
microtubule cytoskeleton organization GO:0000226 157 0.014
Mouse
negative regulation of homeostatic process GO:0032845 71 0.014
phagocytosis GO:0006909 66 0.014
regulation of hormone levels GO:0010817 211 0.014
t helper 17 cell lineage commitment GO:0072540 4 0.014
negative regulation of cell development GO:0010721 169 0.014
Mouse
gene silencing GO:0016458 38 0.013
Mouse Worm
regulation of ion transport GO:0043269 215 0.013
regulation of dna binding GO:0051101 39 0.013
cellular amide metabolic process GO:0043603 58 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
negative regulation of leukocyte differentiation GO:1902106 51 0.013
atp catabolic process GO:0006200 55 0.013
Worm
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 4 0.013
response to organonitrogen compound GO:0010243 246 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.013
cell adhesion GO:0007155 329 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
divalent inorganic cation transport GO:0072511 178 0.013
angiogenesis GO:0001525 201 0.013
Mouse
antimicrobial peptide biosynthetic process GO:0002777 2 0.013
cation transmembrane transport GO:0098655 266 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of lymphocyte mediated immunity GO:0002706 84 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
Worm
regulation of epithelial cell proliferation GO:0050678 141 0.013
regulation of cell motility GO:2000145 236 0.013
regulation of ossification GO:0030278 112 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of homeostatic process GO:0032844 182 0.012
regulation of rig i signaling pathway GO:0039535 2 0.012
organic hydroxy compound transport GO:0015850 93 0.012
positive regulation of rig i signaling pathway GO:1900246 1 0.012
regulation of interleukin 12 production GO:0032655 30 0.012
regulation of hydrolase activity GO:0051336 246 0.012
skeletal system development GO:0001501 356 0.012
Mouse
neuron apoptotic process GO:0051402 142 0.012
positive regulation of leukocyte mediated immunity GO:0002705 70 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.012
response to light stimulus GO:0009416 135 0.012
spermatid differentiation GO:0048515 115 0.012
modification by symbiont of host morphology or physiology GO:0044003 4 0.012
regulation of cytokine production GO:0001817 266 0.012
muscle cell differentiation GO:0042692 261 0.012
Mouse
ossification GO:0001503 216 0.012
development of primary sexual characteristics GO:0045137 143 0.012
lipid biosynthetic process GO:0008610 179 0.012
extracellular matrix organization GO:0030198 147 0.012
spermatid development GO:0007286 108 0.012
response to extracellular stimulus GO:0009991 127 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
neuron death GO:0070997 154 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
response to exogenous dsrna GO:0043330 22 0.012
Mouse
single organism nuclear import GO:1902593 95 0.012
regulation of antimicrobial peptide production GO:0002784 1 0.012
positive regulation of chemokine production GO:0032722 22 0.012
multicellular organism growth GO:0035264 161 0.012
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.012
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
lipid transport GO:0006869 98 0.012
rna interference GO:0016246 2 0.012
Mouse Worm
negative regulation of innate immune response GO:0045824 17 0.012
positive regulation of cell death GO:0010942 224 0.011
positive regulation of proteolysis GO:0045862 85 0.011
citrate metabolic process GO:0006101 3 0.011
intracellular mrna localization GO:0008298 4 0.011
negative regulation of regulatory t cell differentiation GO:0045590 2 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
antigen receptor mediated signaling pathway GO:0050851 64 0.011
regulation of transferase activity GO:0051338 263 0.011
negative regulation of t cell activation GO:0050868 65 0.011
positive regulation of interleukin 6 production GO:0032755 37 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
translation GO:0006412 93 0.011
intestinal epithelial structure maintenance GO:0060729 4 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
hexose metabolic process GO:0019318 98 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
gonad development GO:0008406 141 0.011
type i interferon production GO:0032606 29 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
Worm
negative regulation of protein processing GO:0010955 79 0.011
regulation of defense response to bacterium GO:1900424 3 0.011
mitotic cell cycle process GO:1903047 159 0.011
cell type specific apoptotic process GO:0097285 268 0.011
Mouse
negative regulation of cell activation GO:0050866 111 0.011
toll like receptor 3 signaling pathway GO:0034138 4 0.011
rna processing GO:0006396 105 0.011
Mouse Worm
glucose homeostasis GO:0042593 128 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
Worm
interferon alpha production GO:0032607 7 0.011
negative regulation of molecular function GO:0044092 258 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of secretion GO:0051046 274 0.011
defense response to protozoan GO:0042832 25 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
Mouse
nuclear membrane organization GO:0071763 4 0.011
antigen processing and presentation of peptide antigen GO:0048002 29 0.011
positive t cell selection GO:0043368 23 0.011
appendage development GO:0048736 166 0.011
Mouse
purine containing compound biosynthetic process GO:0072522 70 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
response to host GO:0075136 3 0.011
negative regulation of interleukin 6 production GO:0032715 17 0.011
peptide transport GO:0015833 133 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
intracellular transport of virus GO:0075733 1 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.010
positive regulation of protein import into nucleus GO:0042307 26 0.010
anion transport GO:0006820 177 0.010
positive regulation of cytokine production involved in immune response GO:0002720 19 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
regulation of protein kinase activity GO:0045859 232 0.010
multi multicellular organism process GO:0044706 109 0.010
glial cell differentiation GO:0010001 131 0.010
Mouse
alcohol metabolic process GO:0006066 116 0.010
fertilization GO:0009566 127 0.010
organonitrogen compound catabolic process GO:1901565 264 0.010
Worm
regulation of actin cytoskeleton organization GO:0032956 84 0.010
regulation of protein targeting GO:1903533 61 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010

Dhx58 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.037
organ system cancer DOID:0050686 0 0.037
cancer DOID:162 0 0.037
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.019
disease of metabolism DOID:0014667 0 0.015
acquired metabolic disease DOID:0060158 0 0.010