Mus musculus

418 known processes

Dicer1

Dicer1, Dcr-1 homolog (Drosophila)

(Aliases: 1110006F08Rik,D12Ertd7e,mKIAA0928)

Dicer1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene silencing by mirna GO:0035195 10 0.979
cellular response to organic cyclic compound GO:0071407 87 0.941
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.914
positive regulation of nervous system development GO:0051962 221 0.908
embryonic limb morphogenesis GO:0030326 126 0.881
response to radiation GO:0009314 165 0.873
response to organic cyclic compound GO:0014070 198 0.873
cellular amine metabolic process GO:0044106 44 0.872
response to sterol GO:0036314 4 0.865
organ growth GO:0035265 117 0.808
spermatid differentiation GO:0048515 115 0.804
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.790
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.765
posttranscriptional regulation of gene expression GO:0010608 155 0.764
stem cell differentiation GO:0048863 268 0.762
peptidyl threonine phosphorylation GO:0018107 31 0.729
response to ionizing radiation GO:0010212 42 0.721
primary mirna processing GO:0031053 1 0.717
Worm
cellular response to gamma radiation GO:0071480 4 0.706
ovarian follicle development GO:0001541 40 0.706
negative regulation of cell cycle GO:0045786 123 0.703
axonogenesis GO:0007409 274 0.692
negative regulation of mitotic cell cycle GO:0045930 58 0.689
peptidyl threonine modification GO:0018210 31 0.668
embryonic skeletal system morphogenesis GO:0048704 91 0.662
negative regulation of cell proliferation GO:0008285 296 0.662
cellular ketone metabolic process GO:0042180 84 0.660
dna recombination GO:0006310 92 0.654
stem cell development GO:0048864 219 0.653
regulation of cell cycle GO:0051726 281 0.653
mammary gland morphogenesis GO:0060443 54 0.653
dna metabolic process GO:0006259 303 0.646
Worm
mesenchyme development GO:0060485 152 0.634
germ line stem cell division GO:0042078 2 0.619
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.612
pre mirna processing GO:0031054 3 0.611
posttranscriptional gene silencing GO:0016441 10 0.608
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.603
embryonic skeletal system development GO:0048706 120 0.598
regulation of cellular amine metabolic process GO:0033238 20 0.588
spermatogenesis GO:0007283 284 0.588
epithelial tube morphogenesis GO:0060562 303 0.586
regulation of neuron differentiation GO:0045664 281 0.586
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.581
v d j recombination GO:0033151 14 0.576
diencephalon development GO:0021536 63 0.575
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.573
cell fate commitment GO:0045165 210 0.568
Fly
kidney development GO:0001822 213 0.566
oocyte differentiation GO:0009994 35 0.565
Fly
peptidyl amino acid modification GO:0018193 336 0.547
mesonephric tubule development GO:0072164 94 0.547
stem cell maintenance GO:0019827 130 0.543
cellular response to dna damage stimulus GO:0006974 207 0.539
positive regulation of cell development GO:0010720 237 0.535
cellular response to light stimulus GO:0071482 19 0.525
alpha beta t cell differentiation GO:0046632 69 0.523
regulation of epithelial cell proliferation GO:0050678 141 0.494
regulation of organelle organization GO:0033043 289 0.483
peptidyl serine modification GO:0018209 83 0.470
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.470
hair cycle GO:0042633 90 0.463
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 10 0.462
response to organonitrogen compound GO:0010243 246 0.457
cell proliferation involved in heart valve morphogenesis GO:0003249 1 0.457
somatic cell dna recombination GO:0016444 51 0.448
regulation of cellular ketone metabolic process GO:0010565 66 0.447
positive regulation of growth GO:0045927 104 0.432
regulation of cellular response to stress GO:0080135 159 0.431
male gamete generation GO:0048232 285 0.430
cellular response to radiation GO:0071478 28 0.428
multicellular organism growth GO:0035264 161 0.426
negative regulation of epithelial cell proliferation GO:0050680 64 0.414
amine metabolic process GO:0009308 45 0.411
molting cycle GO:0042303 90 0.407
hair follicle morphogenesis GO:0031069 29 0.407
regionalization GO:0003002 337 0.402
Fly
actin cytoskeleton organization GO:0030036 220 0.389
appendage development GO:0048736 166 0.388
positive regulation of leukocyte differentiation GO:1902107 86 0.384
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.381
regulation of peptidyl serine phosphorylation GO:0033135 39 0.378
negative regulation of dna replication GO:0008156 4 0.376
t cell receptor v d j recombination GO:0033153 5 0.375
negative regulation of growth GO:0045926 99 0.375
positive regulation of neuron differentiation GO:0045666 141 0.372
non recombinational repair GO:0000726 10 0.370
immature b cell differentiation GO:0002327 10 0.366
female sex differentiation GO:0046660 84 0.356
positive regulation of cell death GO:0010942 224 0.354
digestive system development GO:0055123 200 0.353
negative regulation of cell development GO:0010721 169 0.351
male sex differentiation GO:0046661 109 0.345
cellular amino acid metabolic process GO:0006520 103 0.341
cellular response to abiotic stimulus GO:0071214 56 0.341
antral ovarian follicle growth GO:0001547 5 0.340
limb development GO:0060173 166 0.338
t cell differentiation in thymus GO:0033077 77 0.336
digestive tract morphogenesis GO:0048546 147 0.336
myeloid leukocyte differentiation GO:0002573 119 0.332
signal transduction by p53 class mediator GO:0072331 51 0.328
embryonic organ morphogenesis GO:0048562 276 0.327
negative regulation of cellular amine metabolic process GO:0033239 1 0.324
development of primary male sexual characteristics GO:0046546 88 0.323
carbon catabolite activation of transcription GO:0045991 4 0.314
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.313
metanephric mesenchyme morphogenesis GO:0072133 4 0.313
positive regulation of apoptotic process GO:0043065 217 0.312
negative regulation of cell cycle phase transition GO:1901988 48 0.311
positive regulation of immature t cell proliferation GO:0033091 4 0.311
cellular lipid metabolic process GO:0044255 323 0.306
positive regulation of t cell differentiation GO:0045582 52 0.304
kidney epithelium development GO:0072073 121 0.300
regulation of cell motility GO:2000145 236 0.297
nephron epithelium morphogenesis GO:0072088 68 0.296
lymphocyte differentiation GO:0030098 242 0.294
lung development GO:0030324 164 0.289
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.288
regulation of smad protein import into nucleus GO:0060390 3 0.282
maintenance of location GO:0051235 89 0.274
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.270
forebrain development GO:0030900 302 0.270
t cell differentiation GO:0030217 174 0.265
regulation of cell migration GO:0030334 219 0.265
positive regulation of smad protein import into nucleus GO:0060391 2 0.264
response to uv GO:0009411 44 0.263
leukocyte differentiation GO:0002521 342 0.262
mammary gland epithelium development GO:0061180 65 0.259
cell division GO:0051301 120 0.258
regulation of chromosome organization GO:0033044 83 0.258
germ cell development GO:0007281 185 0.255
Fly
t cell selection GO:0045058 34 0.254
regulation of mitotic cell cycle GO:0007346 126 0.253
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.252
fused antrum stage GO:0048165 1 0.252
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.249
response to cholesterol GO:0070723 4 0.248
positive regulation of apoptotic signaling pathway GO:2001235 95 0.245
response to extracellular stimulus GO:0009991 127 0.243
Fly
hair follicle development GO:0001942 85 0.237
lipid localization GO:0010876 126 0.234
regulation of t cell differentiation GO:0045580 83 0.234
gene silencing GO:0016458 38 0.234
regulation of protein stability GO:0031647 52 0.232
meiotic nuclear division GO:0007126 115 0.230
Worm
embryonic appendage morphogenesis GO:0035113 126 0.230
negative regulation of cellular protein metabolic process GO:0032269 247 0.226
limb morphogenesis GO:0035108 149 0.226
lymphocyte proliferation GO:0046651 164 0.225
inflammatory response GO:0006954 244 0.223
anatomical structure homeostasis GO:0060249 145 0.223
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.219
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.219
tolerance induction to self antigen GO:0002513 4 0.218
response to steroid hormone GO:0048545 56 0.218
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.214
positive regulation of neuron projection development GO:0010976 79 0.212
glycoprotein metabolic process GO:0009100 116 0.211
gonad development GO:0008406 141 0.210
Worm
regulation of cardiac muscle cell proliferation GO:0060043 23 0.209
negative regulation of protein metabolic process GO:0051248 282 0.209
spermatid development GO:0007286 108 0.205
regulation of mesenchymal cell proliferation GO:0010464 37 0.205
maternal process involved in female pregnancy GO:0060135 32 0.205
epidermis development GO:0008544 187 0.202
protein autophosphorylation GO:0046777 61 0.201
negative regulation of protein phosphorylation GO:0001933 126 0.199
skin development GO:0043588 220 0.197
cellular response to extracellular stimulus GO:0031668 81 0.197
urogenital system development GO:0001655 261 0.194
covalent chromatin modification GO:0016569 163 0.192
nephron tubule development GO:0072080 84 0.191
nephron tubule morphogenesis GO:0072078 68 0.191
somatic diversification of t cell receptor genes GO:0002568 5 0.190
regulation of hormone levels GO:0010817 211 0.190
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.190
positive regulation of protein modification process GO:0031401 299 0.190
cell aging GO:0007569 35 0.190
mesenchymal cell development GO:0014031 93 0.189
positive regulation of cellular amine metabolic process GO:0033240 5 0.189
metanephros development GO:0001656 79 0.188
regulation of mitosis GO:0007088 29 0.188
lens development in camera type eye GO:0002088 62 0.188
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.188
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.187
endoderm development GO:0007492 45 0.186
t cell activation GO:0042110 289 0.186
negative regulation of secretion GO:0051048 61 0.186
development of primary sexual characteristics GO:0045137 143 0.184
Worm
gland development GO:0048732 330 0.183
regulation of cellular component biogenesis GO:0044087 181 0.182
smad protein complex assembly GO:0007183 1 0.181
regulation of organ morphogenesis GO:2000027 144 0.181
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.180
gene silencing by rna GO:0031047 19 0.180
double strand break repair GO:0006302 48 0.179
actin filament organization GO:0007015 113 0.179
regulation of establishment of protein localization GO:0070201 181 0.179
homeostasis of number of cells GO:0048872 210 0.177
synapse organization GO:0050808 125 0.177
b cell activation GO:0042113 161 0.176
kidney morphogenesis GO:0060993 83 0.176
defense response to other organism GO:0098542 197 0.174
nephron morphogenesis GO:0072028 69 0.174
appendage morphogenesis GO:0035107 149 0.174
response to light stimulus GO:0009416 135 0.172
ectopic germ cell programmed cell death GO:0035234 9 0.172
negative regulation of protein modification process GO:0031400 163 0.172
epithelial cell proliferation GO:0050673 174 0.171
regulation of bmp signaling pathway GO:0030510 60 0.170
ensheathment of neurons GO:0007272 76 0.170
male gonad development GO:0008584 88 0.169
positive regulation of synapse assembly GO:0051965 18 0.169
cellular response to drug GO:0035690 15 0.167
common partner smad protein phosphorylation GO:0007182 2 0.167
double strand break repair via nonhomologous end joining GO:0006303 10 0.166
negative regulation of osteoblast proliferation GO:0033689 4 0.166
negative regulation of bmp signaling pathway GO:0030514 35 0.165
positive regulation of cell projection organization GO:0031346 95 0.164
peptidyl serine phosphorylation GO:0018105 74 0.164
negative regulation of t cell proliferation GO:0042130 38 0.164
neural precursor cell proliferation GO:0061351 121 0.163
response to drug GO:0042493 75 0.163
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.162
maternal placenta development GO:0001893 20 0.162
regulation of chromatin modification GO:1903308 57 0.162
endodermal cell fate specification GO:0001714 4 0.161
neuronal action potential GO:0019228 54 0.161
regulation of b cell tolerance induction GO:0002661 2 0.160
somatic recombination of t cell receptor gene segments GO:0002681 5 0.159
regulation of apoptotic signaling pathway GO:2001233 197 0.158
embryonic hemopoiesis GO:0035162 23 0.157
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.156
viral process GO:0016032 41 0.154
regulation of alpha beta t cell differentiation GO:0046637 35 0.152
divalent metal ion transport GO:0070838 172 0.152
signal transduction in absence of ligand GO:0038034 55 0.151
ventricular septum morphogenesis GO:0060412 27 0.151
ncrna processing GO:0034470 26 0.151
rna phosphodiester bond hydrolysis GO:0090501 19 0.150
regulation of lymphocyte differentiation GO:0045619 107 0.149
ear development GO:0043583 200 0.149
thymus development GO:0048538 41 0.148
ovulation cycle GO:0042698 59 0.148
cellular response to growth factor stimulus GO:0071363 197 0.147
hematopoietic progenitor cell differentiation GO:0002244 143 0.147
regulation of myeloid leukocyte differentiation GO:0002761 58 0.147
lateral mesodermal cell differentiation GO:0048371 3 0.146
rna processing GO:0006396 105 0.146
purine nucleotide catabolic process GO:0006195 211 0.145
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.145
lung alveolus development GO:0048286 45 0.145
cardiac endothelial cell differentiation GO:0003348 4 0.145
regulation of cardiac muscle tissue growth GO:0055021 26 0.145
somatic diversification of immune receptors GO:0002200 53 0.145
muscle cell differentiation GO:0042692 261 0.145
mitotic cell cycle GO:0000278 195 0.145
Fly
cellular response to external stimulus GO:0071496 88 0.144
apoptotic process involved in mammary gland involution GO:0060057 4 0.144
b cell differentiation GO:0030183 78 0.143
regulation of b cell differentiation GO:0045577 23 0.141
regulation of cell proliferation involved in heart valve morphogenesis GO:0003250 1 0.140
regulation of cell size GO:0008361 72 0.140
production of small rna involved in gene silencing by rna GO:0070918 6 0.140
carbon catabolite regulation of transcription GO:0045990 4 0.139
anti mullerian hormone signaling pathway GO:1990262 1 0.138
negative regulation of chromosome organization GO:2001251 30 0.136
nitrogen compound transport GO:0071705 271 0.136
Fly
odontogenesis GO:0042476 78 0.134
negative regulation of cellular component organization GO:0051129 194 0.133
purine nucleotide metabolic process GO:0006163 302 0.133
carbohydrate derivative biosynthetic process GO:1901137 183 0.133
cell fate specification GO:0001708 72 0.132
genetic imprinting GO:0071514 27 0.132
renal tubule development GO:0061326 87 0.132
regulation of protein transport GO:0051223 163 0.130
histone lysine methylation GO:0034968 50 0.130
cardiac muscle tissue development GO:0048738 130 0.130
protein modification by small protein conjugation or removal GO:0070647 207 0.130
dna damage checkpoint GO:0000077 26 0.129
oogenesis GO:0048477 56 0.129
Fly
hormone metabolic process GO:0042445 86 0.128
neuron projection guidance GO:0097485 141 0.128
cellular response to lipid GO:0071396 145 0.127
digestive tract development GO:0048565 190 0.126
meiotic chromosome segregation GO:0045132 19 0.126
Worm
response to growth factor GO:0070848 198 0.126
branching morphogenesis of an epithelial tube GO:0048754 159 0.125
regulation of peptidyl threonine phosphorylation GO:0010799 12 0.123
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.123
hindbrain development GO:0030902 128 0.123
skeletal system development GO:0001501 356 0.123
stem cell proliferation GO:0072089 117 0.123
negative regulation of apoptotic signaling pathway GO:2001234 104 0.122
regulation of secretion by cell GO:1903530 249 0.122
cation transport GO:0006812 399 0.120
segmentation GO:0035282 93 0.120
Fly
blastocyst development GO:0001824 80 0.119
telomere maintenance GO:0000723 19 0.119
mitotic cell cycle process GO:1903047 159 0.119
dna integrity checkpoint GO:0031570 28 0.118
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.118
axon ensheathment GO:0008366 76 0.117
mesenchymal cell proliferation GO:0010463 44 0.117
female gamete generation GO:0007292 74 0.116
Fly
production of mirnas involved in gene silencing by mirna GO:0035196 6 0.115
odontogenesis of dentin containing tooth GO:0042475 66 0.115
extrinsic apoptotic signaling pathway GO:0097191 126 0.115
tissue homeostasis GO:0001894 115 0.114
response to gamma radiation GO:0010332 22 0.114
macromolecule catabolic process GO:0009057 281 0.113
Worm
regulation of leukocyte differentiation GO:1902105 159 0.112
protein alkylation GO:0008213 81 0.112
histone methylation GO:0016571 71 0.111
ureteric bud morphogenesis GO:0060675 62 0.111
positive regulation of dna templated transcription elongation GO:0032786 2 0.111
regulation of response to dna damage stimulus GO:2001020 34 0.111
regulation of protein localization GO:0032880 231 0.110
positive regulation of b cell tolerance induction GO:0002663 2 0.110
response to monosaccharide GO:0034284 67 0.109
positive regulation of t cell activation GO:0050870 101 0.108
t cell lineage commitment GO:0002360 13 0.108
renal system development GO:0072001 225 0.108
negative regulation of peptide hormone secretion GO:0090278 16 0.107
extracellular matrix organization GO:0030198 147 0.107
regulation of anti mullerian hormone signaling pathway GO:1902612 1 0.106
divalent inorganic cation transport GO:0072511 178 0.105
heterocycle catabolic process GO:0046700 280 0.105
Worm
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.105
regulation of mitotic cell cycle phase transition GO:1901990 73 0.105
regulation of organ growth GO:0046620 61 0.105
regulation of cellular component size GO:0032535 121 0.105
regulation of cell cycle phase transition GO:1901987 77 0.105
cardiac muscle cell proliferation GO:0060038 31 0.104
regulation of lung blood pressure GO:0014916 2 0.104
renal tubule morphogenesis GO:0061333 72 0.104
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.104
wnt signaling pathway GO:0016055 188 0.103
cardiocyte differentiation GO:0035051 87 0.103
positive regulation of transcription by galactose GO:0000411 1 0.102
pallium development GO:0021543 120 0.101
positive regulation of cellular component biogenesis GO:0044089 94 0.101
recombinational repair GO:0000725 21 0.100
organelle fission GO:0048285 170 0.100
Worm
cellular response to steroid hormone stimulus GO:0071383 33 0.099
regulation of canonical wnt signaling pathway GO:0060828 82 0.099
skeletal system morphogenesis GO:0048705 203 0.099
positive t cell selection GO:0043368 23 0.099
bmp signaling pathway GO:0030509 93 0.099
calcium ion transport GO:0006816 159 0.099
cardiac muscle tissue growth GO:0055017 37 0.099
ribonucleoside metabolic process GO:0009119 245 0.098
gastrulation GO:0007369 116 0.098
dna repair GO:0006281 107 0.098
sensory organ morphogenesis GO:0090596 242 0.097
positive regulation of neuron death GO:1901216 28 0.097
camera type eye development GO:0043010 266 0.097
response to alcohol GO:0097305 48 0.097
regulation of histone modification GO:0031056 56 0.096
organic cyclic compound catabolic process GO:1901361 295 0.093
Worm
negative regulation of fibroblast proliferation GO:0048147 14 0.093
aromatic compound catabolic process GO:0019439 286 0.093
Worm
embryonic digit morphogenesis GO:0042733 56 0.093
muscle cell development GO:0055001 133 0.093
negative regulation of secretion by cell GO:1903531 54 0.092
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.092
kidney mesenchyme morphogenesis GO:0072131 4 0.092
cytoplasmic transport GO:0016482 234 0.092
heart morphogenesis GO:0003007 178 0.092
respiratory system development GO:0060541 190 0.091
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 4 0.091
lung morphogenesis GO:0060425 50 0.090
response to oxygen levels GO:0070482 62 0.090
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.090
membrane invagination GO:0010324 17 0.089
positive regulation of cell migration GO:0030335 109 0.089
cellular response to organonitrogen compound GO:0071417 145 0.089
b cell lineage commitment GO:0002326 4 0.089
regulation of cell cycle process GO:0010564 160 0.089
cell growth GO:0016049 130 0.088
artery development GO:0060840 53 0.088
regulation of t cell tolerance induction GO:0002664 6 0.088
lateral mesoderm morphogenesis GO:0048369 3 0.087
central nervous system neuron differentiation GO:0021953 162 0.087
sulfur compound metabolic process GO:0006790 100 0.087
regulation of nuclear division GO:0051783 56 0.087
regulation of fatty acid biosynthetic process GO:0042304 12 0.086
neuron migration GO:0001764 122 0.086
sequestering of calcium ion GO:0051208 18 0.086
striated muscle cell development GO:0055002 125 0.086
nephron development GO:0072006 109 0.085
immunoglobulin mediated immune response GO:0016064 69 0.085
axon guidance GO:0007411 141 0.085
mesonephros development GO:0001823 97 0.084
branching involved in ureteric bud morphogenesis GO:0001658 56 0.084
meiotic cell cycle GO:0051321 122 0.084
immunoglobulin v d j recombination GO:0033152 5 0.083
negative regulation of anoikis GO:2000811 2 0.082
regulation of mapk cascade GO:0043408 248 0.082
striated muscle cell proliferation GO:0014855 39 0.082
chondrocyte hypertrophy GO:0003415 4 0.082
transmission of nerve impulse GO:0019226 76 0.082
endodermal cell fate commitment GO:0001711 12 0.082
nucleoside metabolic process GO:0009116 246 0.082
regulation of muscle tissue development GO:1901861 97 0.081
mesoderm structural organization GO:0048338 1 0.081
leydig cell differentiation GO:0033327 10 0.081
protein localization to nucleus GO:0034504 121 0.081
regulation of cell growth GO:0001558 91 0.081
meiotic cell cycle process GO:1903046 77 0.080
mitotic cell cycle checkpoint GO:0007093 31 0.080
monocarboxylic acid metabolic process GO:0032787 191 0.080
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.080
multicellular organismal homeostasis GO:0048871 164 0.080
insulin secretion GO:0030073 89 0.080
negative regulation of insulin secretion GO:0046676 14 0.079
chondrocyte development GO:0002063 24 0.079
histone modification GO:0016570 159 0.079
regulation of cardiac muscle tissue development GO:0055024 31 0.079
response to x ray GO:0010165 11 0.078
angiogenesis GO:0001525 201 0.078
embryonic viscerocranium morphogenesis GO:0048703 8 0.078
oocyte axis specification GO:0007309 2 0.078
negative regulation of organelle organization GO:0010639 90 0.078
response to peptide hormone GO:0043434 127 0.078
production of molecular mediator of immune response GO:0002440 103 0.078
positive regulation of lymphocyte differentiation GO:0045621 61 0.078
positive regulation of axon extension GO:0045773 20 0.078
lymphocyte homeostasis GO:0002260 64 0.077
neural tube closure GO:0001843 90 0.077
regulation of cellular senescence GO:2000772 6 0.077
apoptotic signaling pathway GO:0097190 306 0.076
t cell proliferation GO:0042098 120 0.076
oocyte development GO:0048599 33 0.076
blastoderm segmentation GO:0007350 13 0.074
Fly
canonical wnt signaling pathway GO:0060070 130 0.074
cell matrix adhesion GO:0007160 68 0.074
pole plasm assembly GO:0007315 2 0.074
adaptive immune response GO:0002250 155 0.073
negative regulation of cell motility GO:2000146 61 0.073
cellular divalent inorganic cation homeostasis GO:0072503 127 0.073
cellular response to peptide hormone stimulus GO:0071375 92 0.072
t cell anergy GO:0002870 4 0.072
negative regulation of endothelial cell proliferation GO:0001937 8 0.072
visual behavior GO:0007632 45 0.072
lipid storage GO:0019915 36 0.072
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.071
negative regulation of cell growth GO:0030308 44 0.071
positive regulation of programmed cell death GO:0043068 218 0.071
neural plate mediolateral regionalization GO:0021998 1 0.071
regulation of protein targeting GO:1903533 61 0.071
ureteric bud development GO:0001657 94 0.071
regulation of cell projection organization GO:0031344 206 0.071
extracellular structure organization GO:0043062 148 0.071
alpha beta t cell activation GO:0046631 91 0.070
dna replication GO:0006260 52 0.070
morphogenesis of a branching epithelium GO:0061138 193 0.070
bronchus morphogenesis GO:0060434 2 0.069
negative regulation of b cell activation GO:0050869 27 0.069
positive regulation of t cell tolerance induction GO:0002666 6 0.069
development of primary female sexual characteristics GO:0046545 73 0.069
chromatin modification GO:0016568 187 0.069
sulfur compound biosynthetic process GO:0044272 37 0.069
synapse assembly GO:0007416 56 0.068
lateral mesoderm formation GO:0048370 3 0.068
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.068
negative regulation of cardiac muscle tissue development GO:0055026 8 0.068
positive regulation of immature t cell proliferation in thymus GO:0033092 3 0.068
positive regulation of cytokine production GO:0001819 174 0.068
Mouse
regulation of transcription by galactose GO:0000409 1 0.068
mesonephric tubule morphogenesis GO:0072171 63 0.067
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.067
cellular response to biotic stimulus GO:0071216 92 0.067
regulation of tolerance induction to self antigen GO:0002649 1 0.067
positive regulation of protein transport GO:0051222 93 0.067
ribonucleoside catabolic process GO:0042454 206 0.067
regulation of binding GO:0051098 111 0.067
epithelium migration GO:0090132 63 0.066
regulation of protein complex assembly GO:0043254 83 0.066
regulation of kinase activity GO:0043549 249 0.066
cellular response to nutrient levels GO:0031669 64 0.066
regulation of feeding behavior GO:0060259 3 0.066
cellular response to starvation GO:0009267 57 0.066
protein processing GO:0016485 163 0.065
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.065

Dicer1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.782
Human
disease of cellular proliferation DOID:14566 0 0.782
Human
organ system cancer DOID:0050686 0 0.782
Human
immune system cancer DOID:0060083 0 0.349
hematologic cancer DOID:2531 0 0.349
endocrine gland cancer DOID:170 0 0.129
disease of anatomical entity DOID:7 0 0.087
Human
musculoskeletal system disease DOID:17 0 0.087
connective tissue disease DOID:65 0 0.087
pancreatic cancer DOID:1793 0 0.087