Mus musculus

221 known processes

Dkk1

dickkopf homolog 1 (Xenopus laevis)

(Aliases: mdkk-1)

Dkk1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
axis elongation involved in somitogenesis GO:0090245 4 0.998
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.997
negative regulation of prostatic bud formation GO:0060686 4 0.994
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.994
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.992
trachea cartilage morphogenesis GO:0060535 4 0.987
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.986
midbrain hindbrain boundary maturation GO:0021732 1 0.986
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.985
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.978
appendage development GO:0048736 166 0.977
regionalization GO:0003002 337 0.975
paraxial mesodermal cell differentiation GO:0048342 2 0.973
appendage morphogenesis GO:0035107 149 0.970
mesonephric tubule development GO:0072164 94 0.970
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.969
paraxial mesodermal cell fate commitment GO:0048343 2 0.968
ureteric bud morphogenesis GO:0060675 62 0.967
hematopoietic stem cell proliferation GO:0071425 13 0.966
mesonephric duct morphogenesis GO:0072180 4 0.965
positive regulation of interleukin 8 secretion GO:2000484 1 0.964
renal tubule development GO:0061326 87 0.962
embryonic appendage morphogenesis GO:0035113 126 0.956
polarity specification of proximal distal axis GO:0010085 2 0.955
branching morphogenesis of an epithelial tube GO:0048754 159 0.954
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.953
mesonephric epithelium development GO:0072163 94 0.951
mesenchyme development GO:0060485 152 0.951
Zebrafish
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.950
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.948
cardiac right atrium morphogenesis GO:0003213 3 0.948
mesonephric duct formation GO:0072181 2 0.946
renal system development GO:0072001 225 0.940
nephron morphogenesis GO:0072028 69 0.940
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.940
mesonephros development GO:0001823 97 0.940
metanephric loop of henle development GO:0072236 4 0.940
regulation of testosterone biosynthetic process GO:2000224 2 0.939
lung induction GO:0060492 3 0.933
kidney development GO:0001822 213 0.931
spemann organizer formation GO:0060061 2 0.930
nephron development GO:0072006 109 0.927
metanephros development GO:0001656 79 0.926
embryonic limb morphogenesis GO:0030326 126 0.925
muscle tissue development GO:0060537 308 0.923
nephron tubule development GO:0072080 84 0.921
renal tubule morphogenesis GO:0061333 72 0.921
limb development GO:0060173 166 0.920
cell proliferation in forebrain GO:0021846 30 0.911
inner medullary collecting duct development GO:0072061 2 0.911
epithelial tube morphogenesis GO:0060562 303 0.911
kidney morphogenesis GO:0060993 83 0.909
regulation of interleukin 8 secretion GO:2000482 2 0.906
kidney epithelium development GO:0072073 121 0.905
urogenital system development GO:0001655 261 0.902
muscle cell development GO:0055001 133 0.902
ureteric bud development GO:0001657 94 0.899
establishment of organ orientation GO:0048561 1 0.898
nephron tubule morphogenesis GO:0072078 68 0.898
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.897
mesonephric tubule morphogenesis GO:0072171 63 0.896
embryonic skeletal system development GO:0048706 120 0.891
establishment of anatomical structure orientation GO:0048560 1 0.889
telencephalon development GO:0021537 186 0.888
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.887
muscle cell differentiation GO:0042692 261 0.887
Human
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.886
bmp signaling pathway GO:0030509 93 0.883
spinal cord association neuron differentiation GO:0021527 14 0.883
nephric duct formation GO:0072179 4 0.881
forelimb morphogenesis GO:0035136 40 0.881
morphogenesis of a polarized epithelium GO:0001738 37 0.878
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.877
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.877
hindbrain development GO:0030902 128 0.875
morphogenesis of a branching structure GO:0001763 203 0.875
central nervous system morphogenesis GO:0021551 2 0.874
stem cell proliferation GO:0072089 117 0.871
striated muscle tissue development GO:0014706 293 0.870
stem cell development GO:0048864 219 0.870
limb morphogenesis GO:0035108 149 0.869
ear morphogenesis GO:0042471 118 0.865
renal vesicle induction GO:0072034 3 0.864
hypophysis morphogenesis GO:0048850 3 0.863
pallium development GO:0021543 120 0.862
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.861
branching involved in ureteric bud morphogenesis GO:0001658 56 0.861
connective tissue development GO:0061448 179 0.857
t cell proliferation GO:0042098 120 0.857
neural tube closure GO:0001843 90 0.856
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.856
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.856
fibroblast growth factor production GO:0090269 4 0.855
morphogenesis of a branching epithelium GO:0061138 193 0.847
embryonic digit morphogenesis GO:0042733 56 0.842
nephron epithelium morphogenesis GO:0072088 68 0.841
dorsal spinal cord development GO:0021516 20 0.841
smoothened signaling pathway GO:0007224 105 0.840
response to fibroblast growth factor GO:0071774 47 0.840
renal outer medulla development GO:0072054 2 0.834
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.833
chondrocyte differentiation GO:0002062 72 0.833
uterus morphogenesis GO:0061038 2 0.829
regulation of fibroblast growth factor production GO:0090270 4 0.829
testosterone biosynthetic process GO:0061370 2 0.826
cerebellum formation GO:0021588 1 0.824
central nervous system vasculogenesis GO:0022009 3 0.823
positive regulation of stem cell proliferation GO:2000648 59 0.821
positive regulation of smoothened signaling pathway GO:0045880 23 0.818
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.817
cervix development GO:0060067 2 0.817
blood vessel morphogenesis GO:0048514 285 0.816
regulation of anagen GO:0051884 1 0.814
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.813
metencephalon development GO:0022037 89 0.812
mesoderm morphogenesis GO:0048332 64 0.812
primary neural tube formation GO:0014020 95 0.810
paramesonephric duct development GO:0061205 3 0.809
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.804
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.801
establishment of endothelial blood brain barrier GO:0014045 3 0.800
development of primary male sexual characteristics GO:0046546 88 0.798
formation of primary germ layer GO:0001704 77 0.798
skeletal muscle fiber development GO:0048741 58 0.797
cop9 signalosome assembly GO:0010387 2 0.797
somatic stem cell maintenance GO:0035019 47 0.796
lung morphogenesis GO:0060425 50 0.791
maintenance of cell number GO:0098727 3 0.790
lung development GO:0030324 164 0.788
leukocyte differentiation GO:0002521 342 0.787
midbrain hindbrain boundary development GO:0030917 9 0.786
sensory organ morphogenesis GO:0090596 242 0.785
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.785
mesenchymal cell proliferation GO:0010463 44 0.783
regulation of chondrocyte differentiation GO:0032330 33 0.783
skeletal system development GO:0001501 356 0.781
forebrain development GO:0030900 302 0.781
mesenchymal cell differentiation GO:0048762 107 0.781
prostate gland morphogenesis GO:0060512 32 0.779
regulation of axon diameter GO:0031133 6 0.778
somitogenesis GO:0001756 69 0.778
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.774
androgen biosynthetic process GO:0006702 4 0.774
midbrain development GO:0030901 35 0.773
embryonic organ morphogenesis GO:0048562 276 0.773
somatotropin secreting cell differentiation GO:0060126 4 0.773
oviduct development GO:0060066 3 0.772
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.766
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.766
atrial cardiac muscle tissue development GO:0003228 5 0.764
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.762
forebrain regionalization GO:0021871 25 0.761
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.761
interleukin 8 secretion GO:0072606 3 0.754
peptidyl tyrosine modification GO:0018212 145 0.753
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.748
morphogenesis of embryonic epithelium GO:0016331 159 0.748
axis elongation GO:0003401 30 0.747
striated muscle cell development GO:0055002 125 0.742
organ induction GO:0001759 21 0.742
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.738
cerebellar granular layer development GO:0021681 13 0.737
lung field specification GO:0060424 3 0.735
regulation of wnt signaling pathway GO:0030111 123 0.730
regulation of organ morphogenesis GO:2000027 144 0.730
renal inner medulla development GO:0072053 3 0.730
neuron projection guidance GO:0097485 141 0.730
skeletal system morphogenesis GO:0048705 203 0.727
outer medullary collecting duct development GO:0072060 1 0.724
establishment of planar polarity GO:0001736 28 0.724
embryonic placenta development GO:0001892 98 0.724
mesonephric tubule formation GO:0072172 11 0.722
primitive streak formation GO:0090009 10 0.722
regulation of mesonephros development GO:0061217 24 0.720
regulation of interleukin 1 beta production GO:0032651 25 0.720
cell proliferation in hindbrain GO:0021534 10 0.717
cell differentiation in spinal cord GO:0021515 53 0.714
cellular amine metabolic process GO:0044106 44 0.712
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.710
regulation of cellular amine metabolic process GO:0033238 20 0.709
kidney rudiment formation GO:0072003 3 0.707
nephron epithelium development GO:0072009 92 0.706
angiogenesis GO:0001525 201 0.702
inner ear morphogenesis GO:0042472 101 0.700
negative regulation of androgen biosynthetic process GO:2000180 1 0.698
positive regulation of nervous system development GO:0051962 221 0.693
embryonic epithelial tube formation GO:0001838 130 0.693
forebrain anterior posterior pattern specification GO:0021797 5 0.691
spinal cord development GO:0021510 81 0.688
mapk cascade GO:0000165 281 0.687
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.686
cerebellar cortex formation GO:0021697 22 0.686
neural tube development GO:0021915 160 0.685
positive regulation of neural precursor cell proliferation GO:2000179 42 0.684
neuron migration GO:0001764 122 0.684
regulation of apoptotic signaling pathway GO:2001233 197 0.684
negative regulation of alcohol biosynthetic process GO:1902931 4 0.683
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.682
regulation of cell projection size GO:0032536 6 0.680
mesenchymal cell development GO:0014031 93 0.678
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.678
neural precursor cell proliferation GO:0061351 121 0.677
head morphogenesis GO:0060323 34 0.677
hindbrain formation GO:0021576 1 0.674
positive regulation of mapk cascade GO:0043410 170 0.673
regulation of epithelial cell proliferation GO:0050678 141 0.671
forebrain neuron development GO:0021884 30 0.671
hindbrain morphogenesis GO:0021575 46 0.670
diencephalon development GO:0021536 63 0.670
prostate gland epithelium morphogenesis GO:0060740 31 0.669
negative regulation of neuron differentiation GO:0045665 101 0.667
regulation of neural precursor cell proliferation GO:2000177 70 0.663
axon guidance GO:0007411 141 0.662
cerebellum development GO:0021549 77 0.658
metanephric nephron morphogenesis GO:0072273 19 0.658
nephric duct morphogenesis GO:0072178 7 0.657
negative regulation of testosterone biosynthetic process GO:2000225 1 0.656
apoptotic signaling pathway GO:0097190 306 0.652
mesodermal cell fate commitment GO:0001710 17 0.650
Human
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.649
Human
pituitary gland development GO:0021983 38 0.649
cell fate specification GO:0001708 72 0.649
auditory receptor cell fate determination GO:0042668 3 0.646
regulation of mesenchymal cell proliferation GO:0010464 37 0.645
respiratory system development GO:0060541 190 0.644
response to parathyroid hormone GO:0071107 3 0.643
central nervous system neuron differentiation GO:0021953 162 0.643
Zebrafish
positive regulation of mesonephros development GO:0061213 20 0.641
negative regulation of bmp signaling pathway GO:0030514 35 0.639
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.638
tube closure GO:0060606 91 0.637
epithelial tube formation GO:0072175 130 0.637
odontogenesis of dentin containing tooth GO:0042475 66 0.635
negative regulation of cell development GO:0010721 169 0.634
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.634
regulation of cardiac muscle cell proliferation GO:0060043 23 0.633
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.633
metanephros morphogenesis GO:0003338 24 0.633
paraxial mesoderm morphogenesis GO:0048340 10 0.632
embryonic skeletal system morphogenesis GO:0048704 91 0.632
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.631
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.629
fungiform papilla development GO:0061196 6 0.627
positive regulation of anagen GO:0051885 1 0.627
regulation of organ formation GO:0003156 34 0.627
glial cell differentiation GO:0010001 131 0.626
positive regulation of cartilage development GO:0061036 18 0.626
muscle fiber development GO:0048747 76 0.625
non canonical wnt signaling pathway GO:0035567 33 0.625
regulation of protein kinase activity GO:0045859 232 0.625
metanephric tubule development GO:0072170 18 0.625
oxygen homeostasis GO:0032364 2 0.624
tube formation GO:0035148 140 0.622
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.621
cerebellum morphogenesis GO:0021587 42 0.617
type b pancreatic cell proliferation GO:0044342 10 0.613
cellular response to parathyroid hormone stimulus GO:0071374 2 0.612
neural tube formation GO:0001841 108 0.612
protein processing GO:0016485 163 0.611
regulation of protein maturation GO:1903317 96 0.611
epidermis development GO:0008544 187 0.608
regulation of morphogenesis of a branching structure GO:0060688 53 0.608
mesoderm formation GO:0001707 62 0.607
prostatic bud formation GO:0060513 10 0.606
extracellular matrix organization GO:0030198 147 0.605
metanephric renal vesicle morphogenesis GO:0072283 12 0.604
prostate gland development GO:0030850 48 0.604
neural tube patterning GO:0021532 43 0.604
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.603
cardiac muscle cell proliferation GO:0060038 31 0.602
stem cell differentiation GO:0048863 268 0.602
regulation of cell activation GO:0050865 289 0.598
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.597
hormone metabolic process GO:0042445 86 0.596
motor neuron migration GO:0097475 4 0.594
small molecule biosynthetic process GO:0044283 132 0.593
regulation of mapk cascade GO:0043408 248 0.593
negative regulation of cell fate specification GO:0009996 4 0.584
Human
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.584
cellular ketone metabolic process GO:0042180 84 0.583
cerebellar cortex development GO:0021695 48 0.583
positive regulation of osteoblast differentiation GO:0045669 34 0.582
mesodermal cell differentiation GO:0048333 22 0.580
Human
regulation of transforming growth factor beta2 production GO:0032909 2 0.578
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.577
cerebellar granule cell differentiation GO:0021707 9 0.576
cartilage morphogenesis GO:0060536 11 0.575
negative regulation of epithelial cell proliferation GO:0050680 64 0.575
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.575
olfactory bulb interneuron development GO:0021891 7 0.574
positive regulation of kidney development GO:0090184 28 0.573
interleukin 8 production GO:0032637 4 0.570
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.569
positive regulation of cellular amine metabolic process GO:0033240 5 0.569
regulation of establishment of planar polarity GO:0090175 28 0.567
metanephric epithelium development GO:0072207 21 0.566
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.566
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.564
forebrain cell migration GO:0021885 58 0.561
tendon formation GO:0035992 4 0.561
odontogenesis GO:0042476 78 0.561
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.560
amine metabolic process GO:0009308 45 0.558
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.554
stem cell maintenance GO:0019827 130 0.554
ear development GO:0043583 200 0.553
cardiac muscle cell differentiation GO:0055007 69 0.552
Human
regulation of cartilage development GO:0061035 44 0.550
negative regulation of molecular function GO:0044092 258 0.549
Human
cell differentiation in hindbrain GO:0021533 24 0.547
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.545
regulation of neuron projection development GO:0010975 169 0.544
regulation of kidney development GO:0090183 40 0.544
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.541
regulation of lymphocyte proliferation GO:0050670 117 0.540
positive regulation of wnt signaling pathway GO:0030177 45 0.539
regulation of transferase activity GO:0051338 263 0.538
regulation of peptidyl serine phosphorylation GO:0033135 39 0.538
Human
regulation of canonical wnt signaling pathway GO:0060828 82 0.537
regulation of muscle tissue development GO:1901861 97 0.536
positive regulation of epithelial cell proliferation GO:0050679 68 0.535
leukocyte proliferation GO:0070661 172 0.535
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.535
foregut regionalization GO:0060423 3 0.533
gastrulation GO:0007369 116 0.532
skin development GO:0043588 220 0.532
positive regulation of programmed cell death GO:0043068 218 0.532
gas homeostasis GO:0033483 3 0.530
cardiac atrium development GO:0003230 24 0.527
ossification GO:0001503 216 0.527
hindlimb morphogenesis GO:0035137 42 0.526
negative regulation of hormone metabolic process GO:0032351 4 0.525
lymphocyte differentiation GO:0030098 242 0.522
dorsal ventral neural tube patterning GO:0021904 28 0.522
extracellular structure organization GO:0043062 148 0.519
regulation of interleukin 1 production GO:0032652 26 0.518
camera type eye development GO:0043010 266 0.517
negative regulation of endopeptidase activity GO:0010951 44 0.516
midgut development GO:0007494 4 0.515
epithelial cell proliferation GO:0050673 174 0.515
female sex differentiation GO:0046660 84 0.513
establishment of blood brain barrier GO:0060856 8 0.512
myotube differentiation GO:0014902 105 0.511
type b pancreatic cell differentiation GO:0003309 13 0.510
lymphocyte proliferation GO:0046651 164 0.508
cardiac septum morphogenesis GO:0060411 46 0.506
regulation of ketone biosynthetic process GO:0010566 2 0.505
cell type specific apoptotic process GO:0097285 268 0.505
forebrain morphogenesis GO:0048853 17 0.501
pyramidal neuron migration GO:0021852 1 0.499
mesenchyme morphogenesis GO:0072132 32 0.498
epithelial cell proliferation involved in mammary gland duct elongation GO:0060750 5 0.497
positive regulation of protein phosphorylation GO:0001934 242 0.497
lung epithelium development GO:0060428 37 0.496
developmental induction GO:0031128 34 0.495
endocrine system development GO:0035270 98 0.494
cerebellar granule cell precursor proliferation GO:0021930 10 0.493
cellular response to growth factor stimulus GO:0071363 197 0.490
negative regulation of fat cell differentiation GO:0045599 36 0.488
negative regulation of cell cycle GO:0045786 123 0.487
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.487
morphogenesis of an epithelial sheet GO:0002011 27 0.487
ventricular septum morphogenesis GO:0060412 27 0.486
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.485
cellular amino acid metabolic process GO:0006520 103 0.484
regulation of asymmetric cell division GO:0009786 4 0.484
positive regulation of ossification GO:0045778 47 0.483
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.483
regulation of bmp signaling pathway GO:0030510 60 0.482
t cell differentiation GO:0030217 174 0.482
regulation of fat cell differentiation GO:0045598 81 0.480
metanephric nephron tubule development GO:0072234 16 0.480
regulation of smoothened signaling pathway GO:0008589 58 0.480
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.478
cardiac chamber morphogenesis GO:0003206 93 0.478
metanephric nephron epithelium development GO:0072243 19 0.477
lung associated mesenchyme development GO:0060484 10 0.475
hair follicle development GO:0001942 85 0.471
regulation of protein processing GO:0070613 96 0.470
negative regulation of axon guidance GO:1902668 8 0.470
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.469
paraxial mesoderm development GO:0048339 18 0.466
muscle tissue morphogenesis GO:0060415 53 0.465
skeletal muscle cell differentiation GO:0035914 66 0.462
cochlea morphogenesis GO:0090103 22 0.460
positive regulation of apoptotic process GO:0043065 217 0.454
regulation of neuron differentiation GO:0045664 281 0.454
axonogenesis GO:0007409 274 0.453
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.453
trophectodermal cell differentiation GO:0001829 21 0.451
chemotaxis GO:0006935 247 0.450
regulation of cell cycle process GO:0010564 160 0.449
pericardium development GO:0060039 16 0.449
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.448
cardiac muscle tissue morphogenesis GO:0055008 44 0.448
male gonad development GO:0008584 88 0.447
mammary gland morphogenesis GO:0060443 54 0.446
peptidyl tyrosine phosphorylation GO:0018108 143 0.445
hemangioblast cell differentiation GO:0060217 1 0.445
embryonic forelimb morphogenesis GO:0035115 32 0.443
male sex differentiation GO:0046661 109 0.442
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.441
negative regulation of apoptotic signaling pathway GO:2001234 104 0.441
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.435
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.434
embryonic heart tube formation GO:0003144 1 0.433
olfactory bulb interneuron differentiation GO:0021889 12 0.431
establishment of tissue polarity GO:0007164 28 0.430
regulation of stem cell proliferation GO:0072091 78 0.430
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.428
regulation of stem cell differentiation GO:2000736 50 0.426
dopaminergic neuron differentiation GO:0071542 14 0.426
trabecula formation GO:0060343 24 0.426
morphogenesis of an epithelial bud GO:0060572 18 0.425
rho protein signal transduction GO:0007266 32 0.424
negative regulation of protein maturation GO:1903318 79 0.424
renal vesicle morphogenesis GO:0072077 15 0.423
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.421
sclerotome development GO:0061056 4 0.420
outflow tract morphogenesis GO:0003151 53 0.419
segmentation GO:0035282 93 0.417
limbic system development GO:0021761 72 0.416
regulation of nucleotide metabolic process GO:0006140 169 0.416
bone morphogenesis GO:0060349 78 0.414
positive regulation of lymphocyte proliferation GO:0050671 70 0.412
renal vesicle development GO:0072087 17 0.411
pancreatic pp cell fate commitment GO:0003329 2 0.411
regulation of ossification GO:0030278 112 0.411
positive regulation of striated muscle tissue development GO:0045844 31 0.409
astrocyte fate commitment GO:0060018 4 0.408
organ growth GO:0035265 117 0.408
neuroblast proliferation GO:0007405 49 0.407
negative regulation of proteolysis GO:0045861 74 0.406
positive regulation of cell division GO:0051781 31 0.405
cerebellar cortex morphogenesis GO:0021696 32 0.405
cell cycle arrest GO:0007050 37 0.404
cardiac chamber development GO:0003205 108 0.404
olfactory bulb development GO:0021772 30 0.404
lobar bronchus development GO:0060482 6 0.404
regulation of osteoblast differentiation GO:0045667 67 0.403
epithelial cell morphogenesis GO:0003382 41 0.403
protein maturation GO:0051604 176 0.402
negative regulation of myeloid cell differentiation GO:0045638 38 0.400
regulation of cellular response to growth factor stimulus GO:0090287 82 0.400
mesoderm development GO:0007498 100 0.399
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.398
olfactory lobe development GO:0021988 32 0.398
gland development GO:0048732 330 0.397
Zebrafish
ras protein signal transduction GO:0007265 77 0.397
response to growth factor GO:0070848 198 0.396
artery development GO:0060840 53 0.395
b cell activation GO:0042113 161 0.388
central nervous system neuron development GO:0021954 67 0.387
chondrocyte development GO:0002063 24 0.387
cytokine production GO:0001816 319 0.387
regulation of cytokine production GO:0001817 266 0.386
actin cytoskeleton organization GO:0030036 220 0.386
negative regulation of immune system process GO:0002683 209 0.385
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.385
metanephric collecting duct development GO:0072205 7 0.385
small gtpase mediated signal transduction GO:0007264 97 0.384
mesenchymal to epithelial transition GO:0060231 12 0.382
regulation of interleukin 8 production GO:0032677 3 0.380
fat cell differentiation GO:0045444 160 0.379
labyrinthine layer development GO:0060711 49 0.378
trachea development GO:0060438 18 0.378
cardiocyte differentiation GO:0035051 87 0.378
Human
negative regulation of hormone biosynthetic process GO:0032353 4 0.376
hippocampus development GO:0021766 52 0.375
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.373
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.373
positive regulation of endothelial cell migration GO:0010595 12 0.373
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.373
neuroendocrine cell differentiation GO:0061101 7 0.372
auditory receptor cell fate specification GO:0042667 1 0.370
regulation of protein secretion GO:0050708 82 0.369
cardiac ventricle development GO:0003231 83 0.365
regulation of cardiac muscle tissue growth GO:0055021 26 0.364
regulation of kinase activity GO:0043549 249 0.363
loop of henle development GO:0072070 10 0.362
nephron tubule formation GO:0072079 20 0.361
positive regulation of cell death GO:0010942 224 0.361
development of primary female sexual characteristics GO:0046545 73 0.360
cardiac muscle tissue development GO:0048738 130 0.356
Human
positive regulation of cell cycle GO:0045787 92 0.356
regulation of lymphocyte activation GO:0051249 240 0.356
muscle cell fate commitment GO:0042693 11 0.356
Human
positive regulation of meiosis GO:0045836 14 0.355
positive regulation of interleukin 8 production GO:0032757 2 0.355
regulation of cytokine secretion GO:0050707 61 0.351
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.349
determination of heart left right asymmetry GO:0061371 48 0.349
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.347
canonical wnt signaling pathway GO:0060070 130 0.347
ameboidal type cell migration GO:0001667 128 0.346
Zebrafish
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.346
trachea morphogenesis GO:0060439 8 0.345
negative regulation of fibroblast growth factor production GO:0090272 2 0.343
pancreatic pp cell differentiation GO:0003312 2 0.343
cerebellar granular layer formation GO:0021684 9 0.342

Dkk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org