|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.950
|
Mouse |
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.943
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.887
|
Mouse Fly |
|
|
establishment of tissue polarity
|
GO:0007164 |
28 |
0.884
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.871
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.841
|
Fly |
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.805
|
Fly |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.802
|
Fly |
|
|
membrane organization
|
GO:0061024 |
245 |
0.796
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.781
|
Human Mouse Worm |
|
|
renal system development
|
GO:0072001 |
225 |
0.772
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.768
|
Human Rat |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.754
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.737
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.728
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.709
|
Human Rat |
|
|
renal tubule development
|
GO:0061326 |
87 |
0.706
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.704
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.698
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.694
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.665
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.647
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.645
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.638
|
Human Mouse Worm |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.637
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.633
|
Mouse Fly |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.627
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.623
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.598
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.574
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.571
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.568
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.557
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.557
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.549
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.537
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.537
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.534
|
Fly |
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.533
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.514
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.514
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.511
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.510
|
Mouse Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.507
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.505
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.502
|
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.501
|
Fly |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.496
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.483
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.473
|
Fly |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.469
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.469
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.463
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.459
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.459
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.447
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.445
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.444
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.442
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.440
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.438
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.438
|
|
|
|
basal protein localization
|
GO:0045175 |
1 |
0.436
|
Fly |
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.430
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.429
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.413
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.409
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.406
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.400
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.383
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.377
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.377
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.376
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.374
|
Human |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.372
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.370
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.369
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
28 |
0.360
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.360
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.353
|
Human |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.345
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.345
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.343
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.343
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.341
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.340
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.340
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.337
|
Fly |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.336
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.334
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.334
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.331
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.331
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.326
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.325
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.324
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.322
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.316
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.316
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.315
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.315
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.314
|
Mouse Worm |
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
27 |
0.312
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.309
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.303
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.299
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.299
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.299
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.298
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.296
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.295
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.291
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.288
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.285
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.285
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.282
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.282
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.281
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.280
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.279
|
Human Mouse Worm |
|
|
neuron maturation
|
GO:0042551 |
29 |
0.279
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.278
|
Mouse Worm |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.278
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.275
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.275
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
13 |
0.271
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.270
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.266
|
Human |
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.266
|
Human |
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.265
|
Fly |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.265
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.262
|
Fly |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.260
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.256
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.256
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.255
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.253
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.252
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.252
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.249
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.249
|
Fly |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.249
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.248
|
Human Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.248
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.247
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.247
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.245
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.242
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.241
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.239
|
Human |
|
|
synaptic vesicle recycling
|
GO:0036465 |
19 |
0.238
|
Mouse |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.238
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.237
|
|
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.237
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.237
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.233
|
|
|
|
apical junction assembly
|
GO:0043297 |
15 |
0.230
|
Human Mouse Worm |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.230
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.229
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.228
|
|
|
|
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:0061350 |
2 |
0.228
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.227
|
Human |
|
|
epidermis development
|
GO:0008544 |
187 |
0.223
|
|
|
|
metanephric collecting duct development
|
GO:0072205 |
7 |
0.223
|
Mouse |
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.222
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.220
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.216
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.215
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.213
|
Human |
|
|
cell maturation
|
GO:0048469 |
127 |
0.212
|
Fly |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.212
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.211
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.210
|
|
|
|
convergent extension
|
GO:0060026 |
14 |
0.210
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.210
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.209
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.209
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.208
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.207
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.206
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.203
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.201
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.201
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.197
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.195
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
16 |
0.194
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.194
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.194
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.194
|
Fly |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.191
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.191
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.190
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.190
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.188
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.186
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.183
|
|
|
|
collecting duct development
|
GO:0072044 |
11 |
0.183
|
Mouse |
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.183
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.181
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.181
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.180
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
10 |
0.180
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.180
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.179
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.174
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.173
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.173
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.173
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.172
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.172
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.171
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.171
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.170
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.170
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.170
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.170
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.170
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.169
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.169
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.168
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.168
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.168
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.167
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.166
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.165
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.165
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.165
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.165
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.164
|
Human |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.164
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.164
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.164
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.164
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.163
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.163
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.163
|
|
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.162
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.161
|
Human |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.161
|
Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.161
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.160
|
Fly |
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.158
|
Human Mouse Worm |
|
|
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
|
GO:0060715 |
2 |
0.158
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.157
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.156
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.156
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.154
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
18 |
0.153
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.153
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.152
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.151
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.151
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.150
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.150
|
Mouse Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.149
|
|
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
4 |
0.149
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.149
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.148
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.148
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.148
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.146
|
|
|
|
tight junction assembly
|
GO:0070830 |
9 |
0.145
|
Human |
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.144
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.144
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.144
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.143
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.143
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.142
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
83 |
0.142
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.140
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.139
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.139
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.139
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.138
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.137
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.136
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.136
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.136
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.135
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.135
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.135
|
|
|
|
cytoskeleton dependent intracellular transport
|
GO:0030705 |
50 |
0.135
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.134
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.134
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.133
|
Mouse Fly |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.133
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.132
|
|
|
|
asymmetric protein localization
|
GO:0008105 |
11 |
0.132
|
Mouse Fly |
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.132
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.132
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.131
|
Mouse |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.130
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.129
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.129
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.128
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.127
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.127
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.125
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.123
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.123
|
|
|
|
courtship behavior
|
GO:0007619 |
5 |
0.122
|
Fly |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.121
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.121
|
|
|
|
regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030947 |
14 |
0.121
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.120
|
Fly |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.119
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.118
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
47 |
0.118
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.118
|
|
|
|
locomotor rhythm
|
GO:0045475 |
8 |
0.118
|
Fly |
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
17 |
0.117
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.117
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.116
|
Mouse Fly |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.116
|
Human |
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.116
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.115
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.115
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.114
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.114
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.114
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.113
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.113
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.111
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.110
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.110
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.110
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.109
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.109
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.109
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.109
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.109
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.109
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.109
|
Human Rat |
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.108
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.108
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.108
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.108
|
|
|
|
embryonic axis specification
|
GO:0000578 |
30 |
0.107
|
Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.107
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.107
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.106
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.106
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.106
|
Human |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.105
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.105
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.105
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.105
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.104
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.104
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.104
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
24 |
0.103
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.103
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.103
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.103
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.101
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.101
|
|
|
|
intraspecies interaction between organisms
|
GO:0051703 |
21 |
0.101
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.100
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.100
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.100
|
|
|
|
neuronal action potential propagation
|
GO:0019227 |
8 |
0.100
|
|
|
|
hard palate development
|
GO:0060022 |
5 |
0.100
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.099
|
|
|
|
retinal blood vessel morphogenesis
|
GO:0061304 |
3 |
0.099
|
|
|
|
oxygen homeostasis
|
GO:0032364 |
2 |
0.099
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.098
|
Fly |
|
|
establishment of planar polarity involved in neural tube closure
|
GO:0090177 |
15 |
0.098
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.097
|
|
|
|
maintenance of cell number
|
GO:0098727 |
3 |
0.097
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.097
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.097
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.096
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.096
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.095
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.095
|
Mouse |
|
|
vascular endothelial growth factor receptor signaling pathway
|
GO:0048010 |
24 |
0.094
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.094
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.094
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.094
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.093
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.093
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.093
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.092
|
Fly |
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.092
|
|
|
|
apical protein localization
|
GO:0045176 |
7 |
0.092
|
Mouse |
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.091
|
Fly |
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.091
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.091
|
|
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.091
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.091
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
22 |
0.090
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
62 |
0.090
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.088
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.088
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.088
|
Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.087
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.087
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.087
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.087
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.087
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.086
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.086
|
|
|
|
memory
|
GO:0007613 |
58 |
0.086
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.086
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.086
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.085
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.085
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.085
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.085
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.084
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.084
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.084
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.084
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.083
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.083
|
Mouse |
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.083
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.082
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.082
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.082
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.081
|
|
|
|
rna 3 end processing
|
GO:0031123 |
20 |
0.081
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.080
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.079
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.079
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.079
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.078
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.078
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.077
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.077
|
|
|
|
insulin secretion involved in cellular response to glucose stimulus
|
GO:0035773 |
36 |
0.077
|
|
|
|
negative regulation of hepatocyte differentiation
|
GO:0070367 |
1 |
0.077
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.077
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.077
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.077
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
28 |
0.075
|
Mouse |
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.075
|
|
|
|
regulation of myelination
|
GO:0031641 |
20 |
0.075
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.074
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.074
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.074
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.074
|
|
|
|
gas homeostasis
|
GO:0033483 |
3 |
0.074
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.074
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.074
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
1 |
0.074
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.074
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.073
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.073
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.073
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.073
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.073
|
Fly |
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.073
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.072
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.072
|
|
|
|
cell proliferation in midbrain
|
GO:0033278 |
2 |
0.072
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.071
|
|
|
|
cellular response to glucose stimulus
|
GO:0071333 |
45 |
0.071
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.071
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.071
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.071
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.071
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.071
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.070
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.070
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.070
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.070
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.070
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
13 |
0.070
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.070
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.070
|
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
3 |
0.069
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.069
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.069
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.069
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.069
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.069
|
Fly |
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.069
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.069
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.068
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.067
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.067
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.067
|
Worm Fly |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.067
|
|
|
|
planar cell polarity pathway involved in neural tube closure
|
GO:0090179 |
14 |
0.067
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.067
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.067
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.066
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.066
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.066
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.065
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.065
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.065
|
|
