|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.928
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.899
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.897
|
Mouse |
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.843
|
Mouse |
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.815
|
Mouse |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.814
|
Fly |
|
|
protein localization to cell junction
|
GO:1902414 |
3 |
0.810
|
Mouse |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.807
|
Fly |
|
|
regulation of glutamate receptor signaling pathway
|
GO:1900449 |
16 |
0.765
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.759
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.757
|
Mouse |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.670
|
Fly |
|
|
basal protein localization
|
GO:0045175 |
1 |
0.666
|
Fly |
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.656
|
Mouse |
|
|
regulation of grooming behavior
|
GO:2000821 |
4 |
0.606
|
Mouse |
|
|
adult behavior
|
GO:0030534 |
135 |
0.601
|
|
|
|
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering
|
GO:0097113 |
3 |
0.599
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.553
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.540
|
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.535
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.526
|
Mouse |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.524
|
Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.504
|
Fly |
|
|
synaptic vesicle recycling
|
GO:0036465 |
19 |
0.493
|
Mouse |
|
|
sensory perception
|
GO:0007600 |
245 |
0.487
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.486
|
Fly |
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.484
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.479
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.476
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.451
|
Mouse Rat |
|
|
apical junction assembly
|
GO:0043297 |
15 |
0.450
|
Mouse Worm |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.432
|
|
|
|
g protein coupled glutamate receptor signaling pathway
|
GO:0007216 |
3 |
0.415
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.392
|
|
|
|
protein localization to synapse
|
GO:0035418 |
11 |
0.391
|
Mouse |
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.356
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.350
|
|
|
|
memory
|
GO:0007613 |
58 |
0.345
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.343
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.336
|
Mouse |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.325
|
Mouse |
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
6 |
0.320
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.313
|
|
|
|
negative regulation of synaptic transmission glutamatergic
|
GO:0051967 |
4 |
0.306
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.299
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.296
|
Mouse Fly |
|
|
positive regulation of membrane potential
|
GO:0045838 |
15 |
0.290
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.282
|
|
|
|
response to pain
|
GO:0048265 |
26 |
0.276
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.276
|
Fly |
|
|
protein kinase a signaling
|
GO:0010737 |
7 |
0.264
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
28 |
0.263
|
Mouse |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.259
|
Mouse Fly |
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.259
|
Mouse Worm |
|
|
directional locomotion
|
GO:0033058 |
3 |
0.258
|
|
|
|
rhodopsin mediated signaling pathway
|
GO:0016056 |
4 |
0.257
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.255
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.255
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.254
|
Mouse |
|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
29 |
0.254
|
|
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.252
|
|
|
|
maintenance of cell number
|
GO:0098727 |
3 |
0.251
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.249
|
Rat |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.248
|
Mouse |
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.248
|
Mouse Worm |
|
|
somatostatin signaling pathway
|
GO:0038170 |
2 |
0.246
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.245
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.239
|
Fly |
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
1 |
0.229
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.224
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.223
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.222
|
|
|
|
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
|
GO:0060715 |
2 |
0.220
|
|
|
|
activation of meiosis involved in egg activation
|
GO:0060466 |
2 |
0.213
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.212
|
Mouse |
|
|
regulation of long term synaptic depression
|
GO:1900452 |
3 |
0.209
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.209
|
Mouse |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.201
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.201
|
|
|
|
negative regulation of hepatocyte differentiation
|
GO:0070367 |
1 |
0.200
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.196
|
|
|
|
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity
|
GO:2000311 |
11 |
0.196
|
|
|
|
social behavior
|
GO:0035176 |
21 |
0.196
|
Mouse |
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.196
|
Mouse Worm |
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
4 |
0.195
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.195
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.194
|
Mouse |
|
|
regulation of saliva secretion
|
GO:0046877 |
2 |
0.193
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.191
|
Mouse Worm |
|
|
olfactory learning
|
GO:0008355 |
2 |
0.188
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.187
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.187
|
Mouse |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.186
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.186
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.185
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
1 |
0.185
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.181
|
Fly |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.181
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.179
|
Mouse |
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.177
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.177
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.171
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.169
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.162
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.161
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.156
|
|
|
|
regulation of relaxation of muscle
|
GO:1901077 |
8 |
0.155
|
|
|
|
grooming behavior
|
GO:0007625 |
16 |
0.152
|
Mouse |
|
|
vesicle localization
|
GO:0051648 |
86 |
0.152
|
Mouse |
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
2 |
0.151
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.150
|
|
|
|
regulation of sensory perception of pain
|
GO:0051930 |
8 |
0.150
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.148
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.148
|
|
|
|
activation of meiosis
|
GO:0090427 |
4 |
0.146
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.145
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.144
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.143
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.141
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.140
|
|
|
|
sympathetic ganglion development
|
GO:0061549 |
9 |
0.139
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.138
|
|
|
|
response to cocaine
|
GO:0042220 |
14 |
0.137
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.136
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.135
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.135
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.135
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.135
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.135
|
Human |
|
|
phasic smooth muscle contraction
|
GO:0014821 |
8 |
0.134
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.133
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.131
|
|
|
|
cell proliferation in midbrain
|
GO:0033278 |
2 |
0.131
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.131
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.131
|
Mouse |
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.129
|
|
|
|
progesterone secretion
|
GO:0042701 |
1 |
0.129
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.129
|
Mouse |
|
|
muscle system process
|
GO:0003012 |
141 |
0.127
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.127
|
Mouse |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
19 |
0.126
|
Mouse |
|
|
positive regulation of glutamate receptor signaling pathway
|
GO:1900451 |
3 |
0.125
|
|
|
|
negative regulation of mitotic cell cycle embryonic
|
GO:0045976 |
2 |
0.124
|
|
|
|
cerebellum vasculature morphogenesis
|
GO:0061301 |
1 |
0.123
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.123
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.123
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.121
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.120
|
Mouse Rat Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.120
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.119
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.119
|
Mouse Worm |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.118
|
Human |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.117
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.116
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.116
|
Mouse |
|
|
synaptic vesicle fusion to presynaptic membrane
|
GO:0031629 |
3 |
0.115
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.115
|
Mouse |
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.115
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.115
|
Mouse |
|
|
regulation of long term synaptic potentiation
|
GO:1900271 |
4 |
0.114
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.114
|
Mouse Fly |
|
|
defecation
|
GO:0030421 |
1 |
0.113
|
|
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
10 |
0.113
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.113
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.112
|
|
|
|
positive regulation of excitatory postsynaptic membrane potential
|
GO:2000463 |
14 |
0.112
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.111
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.111
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.110
|
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.110
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.109
|
|
|
|
exploration behavior
|
GO:0035640 |
21 |
0.109
|
Mouse |
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
1 |
0.109
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.105
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.105
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.105
|
Mouse |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.105
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.105
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.104
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.104
|
|
|
|
learning
|
GO:0007612 |
98 |
0.103
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.102
|
|
|
|
muscular septum morphogenesis
|
GO:0003150 |
4 |
0.101
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.101
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.100
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.100
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.099
|
Mouse |
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.099
|
Mouse |
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.099
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
28 |
0.099
|
Mouse |
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.099
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.098
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.098
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.098
|
|
|
|
cerebellum vasculature development
|
GO:0061300 |
1 |
0.098
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.098
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
3 |
0.097
|
|
|
|
inner ear receptor cell development
|
GO:0060119 |
39 |
0.095
|
|
|
|
regulation of short term neuronal synaptic plasticity
|
GO:0048172 |
8 |
0.095
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.095
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.094
|
Rat Fly |
|
|
positive regulation of synaptic transmission glutamatergic
|
GO:0051968 |
8 |
0.094
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.093
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.093
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
29 |
0.093
|
|
|
|
regulation of myelination
|
GO:0031641 |
20 |
0.093
|
Mouse |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.093
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.092
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.091
|
Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.091
|
Mouse |
|
|
regulation of sensory perception
|
GO:0051931 |
8 |
0.091
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.091
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.091
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.090
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.090
|
Mouse |
|
|
fear response
|
GO:0042596 |
33 |
0.089
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.089
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.089
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.088
|
|
|
|
regulation of store operated calcium entry
|
GO:2001256 |
4 |
0.088
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.087
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.087
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.087
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.086
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.085
|
|
|
|
sympathetic nervous system development
|
GO:0048485 |
22 |
0.083
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.083
|
|
|
|
courtship behavior
|
GO:0007619 |
5 |
0.082
|
Fly |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.082
|
Fly |
|
|
cerebellum development
|
GO:0021549 |
77 |
0.082
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.082
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.081
|
Mouse |
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.080
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
11 |
0.080
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.080
|
Mouse |
|
|
negative regulation of receptor mediated endocytosis
|
GO:0048261 |
4 |
0.080
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.079
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.078
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.077
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.077
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.076
|
|
|
|
postsynaptic membrane organization
|
GO:0001941 |
18 |
0.076
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.076
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.076
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.075
|
|
|
|
peristalsis
|
GO:0030432 |
8 |
0.075
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.075
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.075
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
33 |
0.075
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.073
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.073
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.073
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.072
|
Mouse Fly |
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.072
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.071
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.071
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.071
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.071
|
|
|
|
phototransduction
|
GO:0007602 |
17 |
0.070
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.070
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.070
|
|
|
|
regulation of cd24 biosynthetic process
|
GO:2000559 |
1 |
0.069
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.069
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.069
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.069
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.069
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.068
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.068
|
|
|
|
regulation of protein kinase a signaling
|
GO:0010738 |
6 |
0.067
|
|
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
23 |
0.067
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.067
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.067
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.067
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.067
|
Mouse |
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.067
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.066
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.066
|
Mouse |
|
|
exocytosis
|
GO:0006887 |
121 |
0.066
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.065
|
Mouse |
|
|
myelination
|
GO:0042552 |
74 |
0.065
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
128 |
0.065
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.065
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.065
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.065
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.064
|
Mouse |
|
|
locomotory exploration behavior
|
GO:0035641 |
10 |
0.064
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.064
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.064
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.064
|
|
|
|
vocalization behavior
|
GO:0071625 |
7 |
0.063
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.063
|
|
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.063
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
43 |
0.063
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.062
|
|
|
|
tight junction assembly
|
GO:0070830 |
9 |
0.062
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.061
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.061
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.061
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.061
|
|
|
|
chorion development
|
GO:0060717 |
7 |
0.061
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
16 |
0.060
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.060
|
Fly |
|
|
ovulation
|
GO:0030728 |
15 |
0.060
|
Worm |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.060
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.059
|
Mouse |
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.059
|
Fly |
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.059
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.059
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.058
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.058
|
|
|
|
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway
|
GO:0007196 |
3 |
0.058
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.058
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.058
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.058
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.058
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.057
|
|
|
|
striatal medium spiny neuron differentiation
|
GO:0021773 |
2 |
0.057
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.057
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.056
|
|
|
|
cellular response to ethanol
|
GO:0071361 |
3 |
0.056
|
|
|
|
adaptation of rhodopsin mediated signaling
|
GO:0016062 |
2 |
0.055
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.055
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.055
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.054
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.054
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.054
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.054
|
Mouse |
|
|
locomotor rhythm
|
GO:0045475 |
8 |
0.053
|
Fly |
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.053
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.053
|
Fly |
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.053
|
|
|
|
establishment of planar polarity of embryonic epithelium
|
GO:0042249 |
16 |
0.053
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.053
|
Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.052
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.052
|
Fly |
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.051
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.051
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.051
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.051
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.050
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.050
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.050
|
Fly |
|
|
nuclear import
|
GO:0051170 |
95 |
0.050
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.049
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.049
|
Fly |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.049
|
|
|
|
inclusion body assembly
|
GO:0070841 |
3 |
0.049
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.049
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.049
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.048
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.048
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.048
|
|
|
|
regulation of behavioral fear response
|
GO:2000822 |
2 |
0.047
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.047
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.047
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.046
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.046
|
|
|
|
somatostatin receptor signaling pathway
|
GO:0038169 |
2 |
0.046
|
|
|
|
adherens junction maintenance
|
GO:0034334 |
1 |
0.046
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.046
|
Mouse |
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.046
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.046
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.045
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.045
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.045
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.045
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.045
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.044
|
|
|
|
b 1a b cell differentiation
|
GO:0002337 |
2 |
0.044
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.044
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.044
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.044
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.044
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.044
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.044
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.044
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.044
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.043
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.043
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.043
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.043
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
22 |
0.043
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.043
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.042
|
Mouse |
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.042
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.042
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.042
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.042
|
|
|
|
extracellular matrix cell signaling
|
GO:0035426 |
5 |
0.041
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.041
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.041
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.041
|
Mouse |
|
|
heart process
|
GO:0003015 |
94 |
0.041
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.041
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.041
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.041
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.041
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.041
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.040
|
|
|
|
intraspecies interaction between organisms
|
GO:0051703 |
21 |
0.040
|
Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.040
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.040
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.040
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.040
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.040
|
|
|
|
positive regulation of long term neuronal synaptic plasticity
|
GO:0048170 |
3 |
0.039
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.039
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.039
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.039
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.039
|
|
|
|
positive regulation of synaptic transmission gabaergic
|
GO:0032230 |
8 |
0.039
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.039
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.039
|
Mouse |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.039
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.039
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.039
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.039
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.038
|
Mouse Worm |
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.038
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.038
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.038
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.038
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.038
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.038
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.038
|
|
|
|
positive regulation of axon extension
|
GO:0045773 |
20 |
0.037
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.037
|
Mouse |
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.037
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.037
|
Mouse |
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.037
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.037
|
Mouse |
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.036
|
|
|
|
negative regulation of receptor internalization
|
GO:0002091 |
2 |
0.036
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.036
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.036
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.036
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.036
|
|
|
|
sensory perception of touch
|
GO:0050975 |
2 |
0.035
|
|
|
|
regulation of execution phase of apoptosis
|
GO:1900117 |
9 |
0.035
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.035
|
Mouse |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.035
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.035
|
|
|
|
potassium ion homeostasis
|
GO:0055075 |
4 |
0.035
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.035
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.035
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.035
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.035
|
Mouse |
|
|
t cell cytokine production
|
GO:0002369 |
10 |
0.035
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.034
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.034
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
4 |
0.034
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.034
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.034
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.034
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.034
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.034
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.034
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.034
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.034
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.034
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.034
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.034
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.034
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.034
|
Mouse |
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.033
|
Fly |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.033
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.033
|
|
|
|
synaptic transmission cholinergic
|
GO:0007271 |
7 |
0.033
|
|
|
|
circadian behavior
|
GO:0048512 |
13 |
0.033
|
Fly |
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.033
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.033
|
Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.033
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.033
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.033
|
Mouse |
|
|
positive regulation of amino acid transport
|
GO:0051957 |
4 |
0.032
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.032
|
|
|
|
ganglion development
|
GO:0061548 |
13 |
0.032
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.032
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.032
|
|
|
|
amino acid transmembrane transport
|
GO:0003333 |
37 |
0.032
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.032
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.032
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.032
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.032
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.032
|
|
|
|
positive regulation of cardiac muscle cell apoptotic process
|
GO:0010666 |
3 |
0.032
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.032
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
12 |
0.032
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.032
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.031
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.031
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.031
|
|
