Mus musculus

0 known processes

Dlst

dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

(Aliases: 4930529O08Rik,4632413C10Rik,DLTS,1600017E01Rik)

Dlst biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleoside metabolic process GO:0042278 241 0.179
oxidation reduction process GO:0055114 342 0.166
mitochondrion organization GO:0007005 134 0.120
generation of precursor metabolites and energy GO:0006091 103 0.112
nucleotide metabolic process GO:0009117 332 0.111
cellular lipid metabolic process GO:0044255 323 0.105
transmembrane transport GO:0055085 412 0.105
coenzyme metabolic process GO:0006732 52 0.093
nucleobase containing small molecule metabolic process GO:0055086 352 0.092
cellular amino acid metabolic process GO:0006520 103 0.090
monocarboxylic acid metabolic process GO:0032787 191 0.086
cofactor metabolic process GO:0051186 80 0.081
purine ribonucleotide metabolic process GO:0009150 290 0.076
nucleoside phosphate metabolic process GO:0006753 338 0.069
amine metabolic process GO:0009308 45 0.068
nucleoside triphosphate metabolic process GO:0009141 230 0.067
mitochondrial membrane organization GO:0007006 26 0.065
purine nucleotide metabolic process GO:0006163 302 0.062
purine ribonucleoside metabolic process GO:0046128 241 0.058
cellular amine metabolic process GO:0044106 44 0.057
purine containing compound metabolic process GO:0072521 311 0.056
membrane organization GO:0061024 245 0.055
cellular nitrogen compound catabolic process GO:0044270 280 0.055
ion transmembrane transport GO:0034220 361 0.055
carbohydrate metabolic process GO:0005975 230 0.055
cation transport GO:0006812 399 0.054
regulation of cellular amino acid metabolic process GO:0006521 5 0.054
ribose phosphate metabolic process GO:0019693 291 0.053
cellular ketone metabolic process GO:0042180 84 0.053
nucleoside metabolic process GO:0009116 246 0.052
heterocycle catabolic process GO:0046700 280 0.051
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
glycosyl compound metabolic process GO:1901657 246 0.048
energy derivation by oxidation of organic compounds GO:0015980 77 0.048
organophosphate catabolic process GO:0046434 232 0.048
cytoplasmic transport GO:0016482 234 0.047
citrate metabolic process GO:0006101 3 0.047
negative regulation of cellular protein metabolic process GO:0032269 247 0.046
sulfur compound metabolic process GO:0006790 100 0.046
ribonucleoside metabolic process GO:0009119 245 0.043
germ cell development GO:0007281 185 0.043
aromatic compound catabolic process GO:0019439 286 0.043
protein targeting GO:0006605 143 0.042
lipid catabolic process GO:0016042 69 0.042
organonitrogen compound catabolic process GO:1901565 264 0.041
organic cyclic compound catabolic process GO:1901361 295 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
regulation of membrane potential GO:0042391 192 0.039
protein localization to organelle GO:0033365 185 0.039
cellular lipid catabolic process GO:0044242 52 0.037
spermatogenesis GO:0007283 284 0.036
nitrogen compound transport GO:0071705 271 0.036
regulation of hormone levels GO:0010817 211 0.035
response to organonitrogen compound GO:0010243 246 0.035
response to oxidative stress GO:0006979 123 0.035
cation transmembrane transport GO:0098655 266 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
cellular homeostasis GO:0019725 240 0.032
synaptic transmission GO:0007268 329 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
ribonucleotide metabolic process GO:0009259 291 0.031
purine nucleoside triphosphate catabolic process GO:0009146 203 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
atp metabolic process GO:0046034 75 0.030
inorganic ion transmembrane transport GO:0098660 234 0.030
endomembrane system organization GO:0010256 147 0.030
small molecule catabolic process GO:0044282 71 0.029
nucleotide catabolic process GO:0009166 217 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
telencephalon development GO:0021537 186 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
anion transport GO:0006820 177 0.029
male gamete generation GO:0048232 285 0.028
cellular respiration GO:0045333 38 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.027
ribonucleoside monophosphate metabolic process GO:0009161 80 0.027
forebrain development GO:0030900 302 0.027
rna processing GO:0006396 105 0.027
lipid biosynthetic process GO:0008610 179 0.027
cellular chemical homeostasis GO:0055082 215 0.027
inorganic cation transmembrane transport GO:0098662 207 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
dephosphorylation GO:0016311 129 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
purine containing compound catabolic process GO:0072523 213 0.026
purine nucleoside monophosphate metabolic process GO:0009126 81 0.026
cytokine production GO:0001816 319 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
organelle localization GO:0051640 179 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
action potential GO:0001508 78 0.025
maintenance of location GO:0051235 89 0.025
ras protein signal transduction GO:0007265 77 0.025
fatty acid metabolic process GO:0006631 121 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.024
protein localization to membrane GO:0072657 108 0.024
monocarboxylic acid catabolic process GO:0072329 27 0.024
pallium development GO:0021543 120 0.024
cation homeostasis GO:0055080 212 0.024
intracellular protein transport GO:0006886 204 0.024
nucleoside catabolic process GO:0009164 206 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
purine nucleoside catabolic process GO:0006152 205 0.023
organic acid catabolic process GO:0016054 51 0.023
regulation of organelle organization GO:0033043 289 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
amide transport GO:0042886 138 0.023
tricarboxylic acid metabolic process GO:0072350 5 0.023
protein import GO:0017038 101 0.022
cell adhesion GO:0007155 329 0.022
peptidyl amino acid modification GO:0018193 336 0.022
carboxylic acid transport GO:0046942 100 0.022
regulation of transmembrane transport GO:0034762 128 0.022
carboxylic acid catabolic process GO:0046395 51 0.022
organic anion transport GO:0015711 137 0.022
spermatid differentiation GO:0048515 115 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
regulation of secretion GO:0051046 274 0.022
small molecule biosynthetic process GO:0044283 132 0.022
glycerolipid metabolic process GO:0046486 122 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
developmental maturation GO:0021700 193 0.021
cellular amide metabolic process GO:0043603 58 0.021
establishment of protein localization to membrane GO:0090150 54 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
neuronal action potential GO:0019228 54 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
regulation of secretion by cell GO:1903530 249 0.020
endocytosis GO:0006897 168 0.020
transmission of nerve impulse GO:0019226 76 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
multicellular organism growth GO:0035264 161 0.020
peptide transport GO:0015833 133 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
organelle fission GO:0048285 170 0.019
immune effector process GO:0002252 321 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
regulation of defense response GO:0031347 233 0.019
nadh metabolic process GO:0006734 1 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
multicellular organismal signaling GO:0035637 91 0.019
steroid metabolic process GO:0008202 119 0.018
glucose homeostasis GO:0042593 128 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
positive regulation of protein modification process GO:0031401 299 0.018
regulation of hydrolase activity GO:0051336 246 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
mitochondrial transport GO:0006839 36 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
regulation of ion transport GO:0043269 215 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of neuron death GO:1901214 134 0.017
organic acid biosynthetic process GO:0016053 86 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
exocytosis GO:0006887 121 0.017
acyl coa metabolic process GO:0006637 19 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
regulation of kinase activity GO:0043549 249 0.017
cellular protein complex assembly GO:0043623 116 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
cellular ion homeostasis GO:0006873 165 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
positive regulation of growth GO:0045927 104 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
mitotic cell cycle GO:0000278 195 0.017
lipid localization GO:0010876 126 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of cytokine production GO:0001817 266 0.017
neuron death GO:0070997 154 0.016
neuromuscular process GO:0050905 99 0.016
negative regulation of protein modification process GO:0031400 163 0.016
regulation of protein kinase activity GO:0045859 232 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
organic acid transport GO:0015849 101 0.016
response to endoplasmic reticulum stress GO:0034976 53 0.016
regulation of homeostatic process GO:0032844 182 0.016
regulation of neuron apoptotic process GO:0043523 122 0.016
regulation of mapk cascade GO:0043408 248 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
intracellular mrna localization GO:0008298 4 0.016
apoptotic signaling pathway GO:0097190 306 0.016
forebrain cell migration GO:0021885 58 0.016
response to organic cyclic compound GO:0014070 198 0.016
defecation GO:0030421 1 0.016
regulation of protein complex assembly GO:0043254 83 0.016
telencephalon cell migration GO:0022029 55 0.015
inflammatory response GO:0006954 244 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
mrna metabolic process GO:0016071 84 0.015
sensory perception GO:0007600 245 0.015
hormone secretion GO:0046879 128 0.015
vesicle localization GO:0051648 86 0.015
regulation of protein localization GO:0032880 231 0.015
regulation of transferase activity GO:0051338 263 0.015
myeloid cell differentiation GO:0030099 233 0.015
peptide hormone secretion GO:0030072 109 0.015
monosaccharide metabolic process GO:0005996 106 0.015
lipid modification GO:0030258 65 0.015
homeostasis of number of cells GO:0048872 210 0.015
adult behavior GO:0030534 135 0.015
female gamete generation GO:0007292 74 0.015
macromolecule catabolic process GO:0009057 281 0.015
mapk cascade GO:0000165 281 0.015
thioester metabolic process GO:0035383 19 0.015
microtubule based process GO:0007017 236 0.015
metal ion homeostasis GO:0055065 189 0.015
urogenital system development GO:0001655 261 0.015
response to inorganic substance GO:0010035 96 0.015
camera type eye development GO:0043010 266 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
regulation of cell migration GO:0030334 219 0.015
striated muscle tissue development GO:0014706 293 0.014
protein catabolic process GO:0030163 221 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
leukocyte differentiation GO:0002521 342 0.014
gland development GO:0048732 330 0.014
hippocampus development GO:0021766 52 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
phospholipid metabolic process GO:0006644 87 0.014
cell maturation GO:0048469 127 0.014
carbohydrate homeostasis GO:0033500 128 0.014
protein import into peroxisome matrix GO:0016558 3 0.014
thermosensory behavior GO:0040040 1 0.014
succinyl coa metabolic process GO:0006104 1 0.014
axonogenesis GO:0007409 274 0.014
divalent inorganic cation transport GO:0072511 178 0.014
meiotic nuclear division GO:0007126 115 0.014
sensory organ morphogenesis GO:0090596 242 0.014
regulation of response to wounding GO:1903034 189 0.014
blood vessel morphogenesis GO:0048514 285 0.014
oocyte axis specification GO:0007309 2 0.014
translation GO:0006412 93 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
anion transmembrane transport GO:0098656 71 0.014
nuclear transport GO:0051169 139 0.014
digestive system development GO:0055123 200 0.014
protein maturation GO:0051604 176 0.014
glucose metabolic process GO:0006006 92 0.014
circulatory system process GO:0003013 197 0.014
response to lipopolysaccharide GO:0032496 128 0.014
regulation of cell activation GO:0050865 289 0.013
skeletal system development GO:0001501 356 0.013
rna splicing GO:0008380 54 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of body fluid levels GO:0050878 162 0.013
peptide secretion GO:0002790 114 0.013
smoothened signaling pathway GO:0007224 105 0.013
insulin secretion GO:0030073 89 0.013
wnt signaling pathway GO:0016055 188 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
spermatid development GO:0007286 108 0.013
locomotory behavior GO:0007626 195 0.013
cellular response to lipid GO:0071396 145 0.013
gtp catabolic process GO:0006184 143 0.013
establishment of organelle localization GO:0051656 122 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
regulation of protein transport GO:0051223 163 0.013
response to oxygen levels GO:0070482 62 0.013
lymphocyte differentiation GO:0030098 242 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
lymphocyte proliferation GO:0046651 164 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
rho protein signal transduction GO:0007266 32 0.013
divalent metal ion transport GO:0070838 172 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
negative regulation of molecular function GO:0044092 258 0.013
muscle cell differentiation GO:0042692 261 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
cognition GO:0050890 149 0.013
peptidyl serine phosphorylation GO:0018105 74 0.012
positive regulation of cell death GO:0010942 224 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
protein ubiquitination GO:0016567 171 0.012
regulation of peptide transport GO:0090087 91 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
defense response to bacterium GO:0042742 119 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
response to growth factor GO:0070848 198 0.012
oxidoreduction coenzyme metabolic process GO:0006733 16 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
t cell activation GO:0042110 289 0.012
single organism cell adhesion GO:0098602 156 0.012
lateral inhibition GO:0046331 1 0.012
fatty acid oxidation GO:0019395 28 0.012
epithelial cell development GO:0002064 159 0.012
positive regulation of nervous system development GO:0051962 221 0.012
hindbrain development GO:0030902 128 0.012
regulation of intracellular transport GO:0032386 159 0.012
response to peptide GO:1901652 136 0.012
hexose metabolic process GO:0019318 98 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
mitochondrial translation GO:0032543 4 0.012
gtp metabolic process GO:0046039 144 0.012
leukocyte mediated immunity GO:0002443 174 0.012
pole plasm assembly GO:0007315 2 0.012
lipid transport GO:0006869 98 0.012
establishment of vesicle localization GO:0051650 81 0.012
neuron apoptotic process GO:0051402 142 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
myelination GO:0042552 74 0.012
cofactor biosynthetic process GO:0051188 41 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
alcohol metabolic process GO:0006066 116 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
glycoprotein metabolic process GO:0009100 116 0.012
hormone metabolic process GO:0042445 86 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
organelle assembly GO:0070925 177 0.012
ensheathment of neurons GO:0007272 76 0.012
response to acid chemical GO:0001101 111 0.012
regulation of metal ion transport GO:0010959 106 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
single fertilization GO:0007338 82 0.012
positive regulation of cell development GO:0010720 237 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
protein processing GO:0016485 163 0.012
axon ensheathment GO:0008366 76 0.011
rna interference GO:0016246 2 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
sequestering of calcium ion GO:0051208 18 0.011
renal system development GO:0072001 225 0.011
learning or memory GO:0007611 148 0.011
ear development GO:0043583 200 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
response to peptide hormone GO:0043434 127 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
meiotic cell cycle GO:0051321 122 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
gliogenesis GO:0042063 141 0.011
ossification GO:0001503 216 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
central nervous system neuron development GO:0021954 67 0.011
lipid homeostasis GO:0055088 63 0.011
response to extracellular stimulus GO:0009991 127 0.011
neuron migration GO:0001764 122 0.011
positive regulation of organelle organization GO:0010638 128 0.011
cell activation involved in immune response GO:0002263 126 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
innate immune response GO:0045087 157 0.011
regulation of peptide hormone secretion GO:0090276 75 0.011
blood circulation GO:0008015 195 0.011
protein polymerization GO:0051258 57 0.011
organic hydroxy compound transport GO:0015850 93 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
plasma membrane organization GO:0007009 90 0.011
fertilization GO:0009566 127 0.011
negative regulation of cell development GO:0010721 169 0.011
muscle tissue development GO:0060537 308 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
leukocyte proliferation GO:0070661 172 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
compound eye development GO:0048749 1 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
limbic system development GO:0021761 72 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
response to monosaccharide GO:0034284 67 0.011
regulation of hormone secretion GO:0046883 88 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
nuclear division GO:0000280 158 0.011
glycerophospholipid metabolic process GO:0006650 71 0.010
regulation of cell adhesion GO:0030155 154 0.010
protein transmembrane transport GO:0071806 8 0.010
organic hydroxy compound biosynthetic process GO:1901617 77 0.010
digestive tract morphogenesis GO:0048546 147 0.010
response to light stimulus GO:0009416 135 0.010
histone modification GO:0016570 159 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
regulation of cell motility GO:2000145 236 0.010
sulfur compound biosynthetic process GO:0044272 37 0.010
negative regulation of synapse assembly GO:0051964 3 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
peroxisomal transport GO:0043574 4 0.010
pyridine nucleotide metabolic process GO:0019362 12 0.010
response to topologically incorrect protein GO:0035966 25 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
regulation of neuron differentiation GO:0045664 281 0.010
positive regulation of cell activation GO:0050867 158 0.010
myosin filament assembly GO:0031034 2 0.010
sequestering of metal ion GO:0051238 19 0.010
regulation of cell projection organization GO:0031344 206 0.010
calcium ion transport GO:0006816 159 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010

Dlst disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.027
disease of anatomical entity DOID:7 0 0.027
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.024
brain disease DOID:936 0 0.019
central nervous system disease DOID:331 0 0.019
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
neurodegenerative disease DOID:1289 0 0.014
immune system disease DOID:2914 0 0.010