Mus musculus

49 known processes

Dlx6

distal-less homeobox 6

Dlx6 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
central nervous system neuron differentiation GO:0021953 162 0.987
Mouse
forebrain neuron differentiation GO:0021879 52 0.984
Mouse
ear development GO:0043583 200 0.983
forebrain generation of neurons GO:0021872 63 0.978
Mouse
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.976
Mouse
cerebral cortex neuron differentiation GO:0021895 19 0.970
Mouse
sensory organ morphogenesis GO:0090596 242 0.941
embryonic organ morphogenesis GO:0048562 276 0.940
neuron projection guidance GO:0097485 141 0.921
forebrain neuron fate commitment GO:0021877 13 0.899
Mouse
olfactory lobe development GO:0021988 32 0.889
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.888
Mouse
skeletal system development GO:0001501 356 0.884
Mouse
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.883
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.875
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.872
epidermis development GO:0008544 187 0.867
regulation of organ morphogenesis GO:2000027 144 0.866
axonogenesis GO:0007409 274 0.862
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.860
auditory receptor cell fate determination GO:0042668 3 0.846
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.843
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.837
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.790
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.778
stem cell development GO:0048864 219 0.736
glial cell differentiation GO:0010001 131 0.708
Mouse
forebrain cell migration GO:0021885 58 0.702
cerebellar granule cell precursor proliferation GO:0021930 10 0.698
cell proliferation in hindbrain GO:0021534 10 0.690
diencephalon development GO:0021536 63 0.674
pancreatic pp cell fate commitment GO:0003329 2 0.669
cranial nerve development GO:0021545 41 0.664
Fly
telencephalon development GO:0021537 186 0.663
Mouse
regulation of astrocyte differentiation GO:0048710 20 0.663
regionalization GO:0003002 337 0.649
Mouse Fly
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.646
negative regulation of glial cell differentiation GO:0045686 21 0.646
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.622
renal system development GO:0072001 225 0.621
Mouse
forebrain development GO:0030900 302 0.616
Mouse
muscle contraction GO:0006936 101 0.610
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.607
embryonic heart tube formation GO:0003144 1 0.603
olfactory bulb development GO:0021772 30 0.603
telencephalon cell migration GO:0022029 55 0.603
embryonic limb morphogenesis GO:0030326 126 0.600
neuron migration GO:0001764 122 0.599
pituitary gland development GO:0021983 38 0.598
axon guidance GO:0007411 141 0.583
regulation of glial cell differentiation GO:0045685 41 0.578
Mouse
locomotory behavior GO:0007626 195 0.572
epithelial cell development GO:0002064 159 0.571
odontogenesis of dentin containing tooth GO:0042475 66 0.548
Mouse
forebrain neuron development GO:0021884 30 0.546
cell proliferation in external granule layer GO:0021924 10 0.543
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.540
hindbrain development GO:0030902 128 0.537
blood vessel morphogenesis GO:0048514 285 0.530
somitogenesis GO:0001756 69 0.525
Mouse
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.518
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.513
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.510
ear morphogenesis GO:0042471 118 0.509
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.508
pallium development GO:0021543 120 0.504
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.503
hippocampus development GO:0021766 52 0.499
Mouse
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.492
skeletal system morphogenesis GO:0048705 203 0.492
inflammatory response GO:0006954 244 0.489
chemotaxis GO:0006935 247 0.477
bmp signaling pathway GO:0030509 93 0.476
canonical wnt signaling pathway GO:0060070 130 0.476
regulation of metal ion transport GO:0010959 106 0.473
neural tube closure GO:0001843 90 0.473
kidney development GO:0001822 213 0.472
Mouse
limb morphogenesis GO:0035108 149 0.469
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.459
subpallium development GO:0021544 20 0.457
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.457
divalent metal ion transport GO:0070838 172 0.453
hindbrain morphogenesis GO:0021575 46 0.452
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.448
molting cycle GO:0042303 90 0.439
cellular ketone metabolic process GO:0042180 84 0.438
gabaergic neuron differentiation GO:0097154 11 0.437
Mouse
forebrain regionalization GO:0021871 25 0.431
dopaminergic neuron differentiation GO:0071542 14 0.426
substrate independent telencephalic tangential migration GO:0021826 8 0.419
cardiac chamber morphogenesis GO:0003206 93 0.416
cellular amino acid metabolic process GO:0006520 103 0.413
ectoderm formation GO:0001705 3 0.412
regulation of fat cell differentiation GO:0045598 81 0.397
transmembrane transport GO:0055085 412 0.394
ion transmembrane transport GO:0034220 361 0.392
embryonic skeletal system morphogenesis GO:0048704 91 0.391
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.389
cell differentiation in hindbrain GO:0021533 24 0.384
wnt signaling pathway GO:0016055 188 0.381
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.378
regulation of muscle contraction GO:0006937 49 0.378
sensory perception GO:0007600 245 0.375
inorganic ion transmembrane transport GO:0098660 234 0.374
stem cell differentiation GO:0048863 268 0.370
cerebral cortex gabaergic interneuron development GO:0021894 6 0.365
somatotropin secreting cell differentiation GO:0060126 4 0.361
dentate gyrus development GO:0021542 14 0.359
limbic system development GO:0021761 72 0.355
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.355
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.339
regulation of cellular amine metabolic process GO:0033238 20 0.339
hypophysis morphogenesis GO:0048850 3 0.332
ossification GO:0001503 216 0.329
epithelial cell morphogenesis GO:0003382 41 0.325
inorganic cation transmembrane transport GO:0098662 207 0.320
regulation of neuron projection development GO:0010975 169 0.317
globus pallidus development GO:0021759 2 0.315
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.309
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.305
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.302
Mouse
mesenchyme development GO:0060485 152 0.301
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.301
regulation of heart morphogenesis GO:2000826 22 0.301
hemangioblast cell differentiation GO:0060217 1 0.299
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.294
regulation of system process GO:0044057 200 0.291
positive regulation of stem cell proliferation GO:2000648 59 0.290
neuron projection extension GO:1990138 64 0.290
locus ceruleus development GO:0021703 1 0.289
regulation of homeostatic process GO:0032844 182 0.288
neuron fate specification GO:0048665 30 0.280
interneuron migration from the subpallium to the cortex GO:0021830 7 0.280
urogenital system development GO:0001655 261 0.272
Mouse
determination of dorsal ventral asymmetry GO:0048262 5 0.270
Fly
epithelial cell proliferation GO:0050673 174 0.266
astrocyte fate commitment GO:0060018 4 0.263
connective tissue development GO:0061448 179 0.263
prostate gland morphogenesis GO:0060512 32 0.260
Mouse
cerebral cortex radially oriented cell migration GO:0021799 31 0.259
lipid biosynthetic process GO:0008610 179 0.258
regulation of wnt signaling pathway GO:0030111 123 0.255
lymphocyte differentiation GO:0030098 242 0.254
cation transport GO:0006812 399 0.251
corticotropin hormone secreting cell differentiation GO:0060128 3 0.251
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.250
regulation of ion transport GO:0043269 215 0.250
synaptic transmission GO:0007268 329 0.250
osteoblast development GO:0002076 17 0.247
positive regulation of epithelial cell proliferation GO:0050679 68 0.246
gastrulation GO:0007369 116 0.245
trachea formation GO:0060440 3 0.244
central nervous system neuron development GO:0021954 67 0.240
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.237
positive regulation of protein modification process GO:0031401 299 0.237
oligodendrocyte development GO:0014003 20 0.236
formation of primary germ layer GO:0001704 77 0.236
embryonic skeletal system development GO:0048706 120 0.234
Mouse
negative regulation of astrocyte differentiation GO:0048712 10 0.231
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.230
embryonic placenta development GO:0001892 98 0.230
odontogenesis GO:0042476 78 0.230
Mouse
cardiocyte differentiation GO:0035051 87 0.228
paraxial mesodermal cell fate commitment GO:0048343 2 0.227
myotube differentiation GO:0014902 105 0.227
gliogenesis GO:0042063 141 0.226
Mouse
limb development GO:0060173 166 0.223
negative regulation of lipid metabolic process GO:0045833 30 0.223
tendon formation GO:0035992 4 0.223
negative regulation of neuron differentiation GO:0045665 101 0.221
regulation of cellular ketone metabolic process GO:0010565 66 0.220
mesenchymal cell differentiation GO:0048762 107 0.219
regulation of ossification GO:0030278 112 0.218
mesenchymal cell development GO:0014031 93 0.218
regulation of auditory receptor cell differentiation GO:0045607 4 0.217
feeding behavior GO:0007631 62 0.212
organic hydroxy compound biosynthetic process GO:1901617 77 0.212
heart field specification GO:0003128 6 0.212
hindbrain tangential cell migration GO:0021934 2 0.212
regulation of membrane potential GO:0042391 192 0.212
nerve development GO:0021675 67 0.210
Fly
cell fate specification GO:0001708 72 0.207
cell proliferation in forebrain GO:0021846 30 0.206
cerebral cortex development GO:0021987 86 0.205
regulation of blood pressure GO:0008217 93 0.205
branching morphogenesis of an epithelial tube GO:0048754 159 0.204
Mouse
cell fate commitment GO:0045165 210 0.204
Mouse
auditory receptor cell fate specification GO:0042667 1 0.202
olfactory nerve development GO:0021553 3 0.202
Fly
semicircular canal formation GO:0060876 1 0.202
brain segmentation GO:0035284 3 0.201
embryonic viscerocranium morphogenesis GO:0048703 8 0.201
regulation of endodermal cell fate specification GO:0042663 2 0.199
skeletal muscle organ development GO:0060538 163 0.197
divalent inorganic cation transport GO:0072511 178 0.196
germ cell development GO:0007281 185 0.194
muscle system process GO:0003012 141 0.194
regulation of mast cell differentiation GO:0060375 3 0.194
peripheral nervous system neuron axonogenesis GO:0048936 3 0.190
cognition GO:0050890 149 0.189
inner ear morphogenesis GO:0042472 101 0.189
hair follicle development GO:0001942 85 0.188
fat cell differentiation GO:0045444 160 0.188
cardiac epithelial to mesenchymal transition GO:0060317 18 0.187
positive regulation of protein phosphorylation GO:0001934 242 0.187
negative regulation of molecular function GO:0044092 258 0.186
nephron tubule morphogenesis GO:0072078 68 0.182
lateral motor column neuron migration GO:0097477 3 0.181
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.181
cardiac muscle tissue development GO:0048738 130 0.180
cytoplasmic transport GO:0016482 234 0.174
regulation of muscle tissue development GO:1901861 97 0.174
cardiac muscle cell differentiation GO:0055007 69 0.173
metanephric capsule specification GO:0072267 1 0.172
catecholamine metabolic process GO:0006584 30 0.172
response to extracellular stimulus GO:0009991 127 0.172
embryonic genitalia morphogenesis GO:0030538 4 0.171
spinal cord motor neuron differentiation GO:0021522 35 0.170
negative regulation of gliogenesis GO:0014014 23 0.169
Mouse
cytokine production GO:0001816 319 0.169
muscle tissue development GO:0060537 308 0.169
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.166
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.166
negative regulation of cell fate specification GO:0009996 4 0.166
metencephalon development GO:0022037 89 0.166
sensory system development GO:0048880 3 0.165
cardiac right ventricle formation GO:0003219 3 0.165
muscle cell differentiation GO:0042692 261 0.165
endochondral bone morphogenesis GO:0060350 50 0.165
posttranscriptional regulation of gene expression GO:0010608 155 0.164
regulation of neural precursor cell proliferation GO:2000177 70 0.163
digestive tract morphogenesis GO:0048546 147 0.162
carbohydrate metabolic process GO:0005975 230 0.161
cartilage morphogenesis GO:0060536 11 0.160
metanephros development GO:0001656 79 0.160
Mouse
pyramidal neuron migration GO:0021852 1 0.159
cation transmembrane transport GO:0098655 266 0.159
lung induction GO:0060492 3 0.158
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.154
cerebellar cortex development GO:0021695 48 0.153
cerebral cortex cell migration GO:0021795 44 0.152
sensory perception of sound GO:0007605 97 0.152
positive regulation of lymphocyte activation GO:0051251 140 0.152
blood circulation GO:0008015 195 0.152
hair cell differentiation GO:0035315 40 0.151
notch signaling pathway GO:0007219 71 0.151
Mouse
central nervous system segmentation GO:0035283 3 0.151
tube formation GO:0035148 140 0.151
cardiac septum development GO:0003279 59 0.150
renal system process GO:0003014 48 0.150
respiratory system development GO:0060541 190 0.150
organic hydroxy compound metabolic process GO:1901615 203 0.149
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.148
midbrain development GO:0030901 35 0.148
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.147
multicellular organismal signaling GO:0035637 91 0.146
lens morphogenesis in camera type eye GO:0002089 24 0.146
positive regulation of ossification GO:0045778 47 0.145
spermatogenesis GO:0007283 284 0.144
cellular chemical homeostasis GO:0055082 215 0.142
neural crest cell development GO:0014032 48 0.141
positive regulation of transcription via serum response element binding GO:0010735 1 0.140
midbrain hindbrain boundary maturation GO:0021732 1 0.140
spinal cord dorsal ventral patterning GO:0021513 23 0.140
trophectodermal cell differentiation GO:0001829 21 0.140
motor neuron migration GO:0097475 4 0.139
neuron death GO:0070997 154 0.138
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.137
small molecule biosynthetic process GO:0044283 132 0.137
amine metabolic process GO:0009308 45 0.135
neural crest cell differentiation GO:0014033 54 0.135
appendage development GO:0048736 166 0.135
regulation of osteoblast differentiation GO:0045667 67 0.135
regulation of cardiac muscle tissue development GO:0055024 31 0.133
carbohydrate homeostasis GO:0033500 128 0.132
regulation of heart contraction GO:0008016 77 0.132
regulation of neuron differentiation GO:0045664 281 0.131
proton transport GO:0015992 35 0.131
columnar cuboidal epithelial cell development GO:0002066 29 0.131
negative regulation of phosphate metabolic process GO:0045936 184 0.131
noradrenergic neuron development GO:0003358 3 0.130
olfactory bulb interneuron development GO:0021891 7 0.130
muscle cell proliferation GO:0033002 52 0.130
regulation of ion homeostasis GO:2000021 64 0.130
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.129
sequestering of calcium ion GO:0051208 18 0.129
morphogenesis of a branching structure GO:0001763 203 0.129
Mouse
positive regulation of cell cycle GO:0045787 92 0.128
peptide transport GO:0015833 133 0.128
positive regulation of wnt signaling pathway GO:0030177 45 0.127
nitrogen compound transport GO:0071705 271 0.125
membrane organization GO:0061024 245 0.124
prostate gland development GO:0030850 48 0.124
Mouse
cartilage development GO:0051216 140 0.124
endodermal cell fate commitment GO:0001711 12 0.123
cerebellar cortex morphogenesis GO:0021696 32 0.122
immunoglobulin mediated immune response GO:0016064 69 0.121
cerebellar cortex formation GO:0021697 22 0.121
positive regulation of dna templated transcription elongation GO:0032786 2 0.121
branching involved in ureteric bud morphogenesis GO:0001658 56 0.120
cellular homeostasis GO:0019725 240 0.120
regulation of canonical wnt signaling pathway GO:0060828 82 0.119
alpha beta t cell differentiation GO:0046632 69 0.119
primary neural tube formation GO:0014020 95 0.118
positive regulation of growth GO:0045927 104 0.118
inner ear receptor cell differentiation GO:0060113 61 0.118
positive regulation of programmed cell death GO:0043068 218 0.118
negative regulation of cell proliferation GO:0008285 296 0.118
Mouse
adenohypophysis development GO:0021984 14 0.117
oligodendrocyte differentiation GO:0048709 53 0.117
Mouse
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.117
placenta development GO:0001890 140 0.115
cellular response to lipid GO:0071396 145 0.115
regulation of transcription involved in cell fate commitment GO:0060850 15 0.115
Mouse
multi multicellular organism process GO:0044706 109 0.113
protein import into nucleus GO:0006606 95 0.113
gland development GO:0048732 330 0.112
Mouse
embryonic epithelial tube formation GO:0001838 130 0.112
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.112
negative regulation of prostatic bud formation GO:0060686 4 0.111
mitral valve development GO:0003174 4 0.111
neural tube formation GO:0001841 108 0.111
hypothalamus cell differentiation GO:0021979 8 0.111
cation homeostasis GO:0055080 212 0.111
sinoatrial node cell differentiation GO:0060921 3 0.110
response to organic cyclic compound GO:0014070 198 0.110
Mouse
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.109
chromatin modification GO:0016568 187 0.109
regulation of epidermal cell differentiation GO:0045604 21 0.109
endodermal cell fate specification GO:0001714 4 0.108
regulation of organ formation GO:0003156 34 0.108
cellular amine metabolic process GO:0044106 44 0.108
negative regulation of phosphorus metabolic process GO:0010563 184 0.108
appendage morphogenesis GO:0035107 149 0.107
striated muscle tissue development GO:0014706 293 0.107
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.107
regulation of cellular amino acid metabolic process GO:0006521 5 0.107
mapk cascade GO:0000165 281 0.107
angiogenesis GO:0001525 201 0.106
skin morphogenesis GO:0043589 38 0.106
myoblast differentiation GO:0045445 52 0.106
middle ear morphogenesis GO:0042474 23 0.105
bone development GO:0060348 120 0.105
peripheral nervous system neuron development GO:0048935 9 0.105
cerebral cortex tangential migration GO:0021800 7 0.105
morphogenesis of a branching epithelium GO:0061138 193 0.104
Mouse
telencephalon regionalization GO:0021978 14 0.104
pancreatic pp cell differentiation GO:0003312 2 0.104
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.104
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.104
negative regulation of proteolysis GO:0045861 74 0.104
positive regulation of organelle organization GO:0010638 128 0.102
oviduct development GO:0060066 3 0.101
axis elongation involved in somitogenesis GO:0090245 4 0.101
regulation of endodermal cell differentiation GO:1903224 2 0.100
olfactory pit development GO:0060166 3 0.099
astrocyte differentiation GO:0048708 43 0.098
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.098
learning or memory GO:0007611 148 0.098
his purkinje system cell differentiation GO:0060932 2 0.097
negative regulation of neuron death GO:1901215 98 0.097
Mouse
heart morphogenesis GO:0003007 178 0.096
morphogenesis of an epithelial sheet GO:0002011 27 0.096
mitochondrion organization GO:0007005 134 0.095
regulation of secretion by cell GO:1903530 249 0.095
tendon cell differentiation GO:0035990 4 0.095
regulation of cell migration GO:0030334 219 0.095
cellular metal ion homeostasis GO:0006875 151 0.095
t cell activation GO:0042110 289 0.094
salivary gland morphogenesis GO:0007435 33 0.093
Mouse
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.093
leukocyte proliferation GO:0070661 172 0.093
cell maturation GO:0048469 127 0.093
mammary placode formation GO:0060596 4 0.093
muscle fiber development GO:0048747 76 0.093
negative regulation of alcohol biosynthetic process GO:1902931 4 0.092
male sex differentiation GO:0046661 109 0.092
Mouse
skin development GO:0043588 220 0.092
regulation of lipid metabolic process GO:0019216 118 0.092
protein localization to organelle GO:0033365 185 0.091
cardiac ventricle development GO:0003231 83 0.091
cardiac right atrium morphogenesis GO:0003213 3 0.091
smooth muscle contraction GO:0006939 44 0.091
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.091
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.090
forebrain anterior posterior pattern specification GO:0021797 5 0.090
cerebellum morphogenesis GO:0021587 42 0.090
cerebellum formation GO:0021588 1 0.090
sequestering of metal ion GO:0051238 19 0.090
regulation of cellular response to stress GO:0080135 159 0.089
positive regulation of exit from mitosis GO:0031536 1 0.089
hypothalamus development GO:0021854 16 0.088
cardiac muscle cell development GO:0055013 39 0.087
ventricular cardiac myofibril assembly GO:0055005 3 0.087
development of primary sexual characteristics GO:0045137 143 0.087
Mouse
sodium ion transport GO:0006814 73 0.086
neural crest cell migration GO:0001755 32 0.086
meiotic cell cycle GO:0051321 122 0.086
organic anion transport GO:0015711 137 0.085
mammary gland morphogenesis GO:0060443 54 0.085
embryonic forelimb morphogenesis GO:0035115 32 0.084
response to testosterone GO:0033574 3 0.083
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.083
nephron morphogenesis GO:0072028 69 0.083
apoptotic process involved in morphogenesis GO:0060561 25 0.083
negative regulation of endodermal cell differentiation GO:1903225 1 0.083
segmentation GO:0035282 93 0.083
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.083
glial cell migration GO:0008347 7 0.083
autonomic nervous system development GO:0048483 43 0.082
regulation of transporter activity GO:0032409 57 0.082
mechanoreceptor differentiation GO:0042490 67 0.082
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.082
metanephric dct cell differentiation GO:0072240 3 0.082
positive regulation of cellular amine metabolic process GO:0033240 5 0.082
nucleocytoplasmic transport GO:0006913 139 0.082
developmental maturation GO:0021700 193 0.081
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.081
lateral line system development GO:0048925 1 0.081
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.081
blastocyst development GO:0001824 80 0.081
regulation of retina development in camera type eye GO:1902866 3 0.080
regulation of ion transmembrane transporter activity GO:0032412 54 0.080
protein localization to membrane GO:0072657 108 0.080
regulation of cell cycle GO:0051726 281 0.080
regulation of secretion GO:0051046 274 0.080
paraxial mesodermal cell differentiation GO:0048342 2 0.080
central nervous system vasculogenesis GO:0022009 3 0.080
regulation of muscle system process GO:0090257 80 0.080
regulation of smoothened signaling pathway GO:0008589 58 0.080
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.079
negative regulation of cell development GO:0010721 169 0.079
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 14 0.079
regulation of exit from mitosis GO:0007096 1 0.078
medulla oblongata development GO:0021550 3 0.077
regulation of cellular catabolic process GO:0031329 242 0.077
cerebellum development GO:0021549 77 0.076
negative regulation of cell cycle GO:0045786 123 0.076
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.076
developmental programmed cell death GO:0010623 41 0.076
cellular ion homeostasis GO:0006873 165 0.076
heart induction GO:0003129 2 0.076
response to steroid hormone GO:0048545 56 0.076
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.075
cell migration in hindbrain GO:0021535 16 0.075
circulatory system process GO:0003013 197 0.075
embryonic hindlimb morphogenesis GO:0035116 32 0.075
regulation of transmembrane transport GO:0034762 128 0.075
ureteric bud development GO:0001657 94 0.074
trochlear nerve development GO:0021558 3 0.074
negative regulation of notch signaling pathway GO:0045746 14 0.074
Mouse
negative regulation of nervous system development GO:0051961 156 0.074
Mouse
regulation of ketone biosynthetic process GO:0010566 2 0.073
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.073
chromatin organization GO:0006325 206 0.073
kidney morphogenesis GO:0060993 83 0.073
regulation of mapk cascade GO:0043408 248 0.073
neuroblast differentiation GO:0014016 2 0.073
pharyngeal system development GO:0060037 17 0.073
Mouse
regulation of gliogenesis GO:0014013 50 0.072
Mouse
rhombomere 3 morphogenesis GO:0021658 2 0.072
amide transport GO:0042886 138 0.071
pancreatic a cell fate commitment GO:0003326 2 0.071
nuclear import GO:0051170 95 0.071
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.071
hair cycle GO:0042633 90 0.070
leukocyte differentiation GO:0002521 342 0.070
negative regulation of bmp signaling pathway GO:0030514 35 0.070
cell type specific apoptotic process GO:0097285 268 0.070
Mouse
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.070
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.070
dendrite development GO:0016358 115 0.070
protein import GO:0017038 101 0.070
digestive tract development GO:0048565 190 0.069
positive regulation of protein kinase activity GO:0045860 144 0.069
cellular response to hormone stimulus GO:0032870 150 0.069
protein kinase b signaling GO:0043491 74 0.069
Mouse
nuclear transport GO:0051169 139 0.069
mesonephric tubule development GO:0072164 94 0.069
negative regulation of oligodendrocyte differentiation GO:0048715 11 0.069
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.068
atrial ventricular junction remodeling GO:0003294 2 0.068
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.068
synapse organization GO:0050808 125 0.068
methylation GO:0032259 134 0.068
single organism nuclear import GO:1902593 95 0.068
calcium ion transport GO:0006816 159 0.068
noradrenergic neuron differentiation GO:0003357 6 0.067
olfactory bulb interneuron differentiation GO:0021889 12 0.067
neurohypophysis development GO:0021985 2 0.067
mammary gland bud formation GO:0060615 2 0.067
mammary gland duct morphogenesis GO:0060603 38 0.067
regulation of ion transmembrane transport GO:0034765 119 0.067
regulation of skeletal muscle cell differentiation GO:2001014 11 0.067
epithelial tube morphogenesis GO:0060562 303 0.067
Mouse
striatum development GO:0021756 14 0.067
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.067

Dlx6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.127
musculoskeletal system disease DOID:17 0 0.127