Mus musculus

76 known processes

Drd4

dopamine receptor D4

(Aliases: AW125663,Drd-4,D4R)

Drd4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transferase activity GO:0051338 263 0.652
Human
conditioned taste aversion GO:0001661 4 0.557
forebrain development GO:0030900 302 0.510
Mouse
gastrin induced gastric acid secretion GO:0001698 1 0.475
cell type specific apoptotic process GO:0097285 268 0.468
neuron death GO:0070997 154 0.396
positive regulation of cell development GO:0010720 237 0.391
Mouse
visual perception GO:0007601 52 0.373
locomotory behavior GO:0007626 195 0.368
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.349
positive regulation of catecholamine secretion GO:0033605 2 0.347
camera type eye development GO:0043010 266 0.338
Rat
regulation of postsynaptic membrane potential GO:0060078 48 0.328
regulation of membrane potential GO:0042391 192 0.326
sensory organ morphogenesis GO:0090596 242 0.325
regulation of protein kinase activity GO:0045859 232 0.312
Human
action potential GO:0001508 78 0.308
nucleobase containing small molecule metabolic process GO:0055086 352 0.307
Human
regulation of body fluid levels GO:0050878 162 0.305
Mouse
regulation of kinase activity GO:0043549 249 0.299
Human
gland development GO:0048732 330 0.295
Mouse
regulation of ion transport GO:0043269 215 0.281
Human Mouse
multicellular organismal homeostasis GO:0048871 164 0.271
Mouse
circadian sleep wake cycle rem sleep GO:0042747 1 0.270
regulation of cell motility GO:2000145 236 0.267
Mouse
synaptic transmission involved in micturition GO:0060084 3 0.249
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.246
tissue homeostasis GO:0001894 115 0.235
negative regulation of molecular function GO:0044092 258 0.230
Human
myeloid cell differentiation GO:0030099 233 0.229
eye photoreceptor cell differentiation GO:0001754 41 0.229
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.224
Rat
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.221
response to radiation GO:0009314 165 0.216
Mouse Rat
peptide secretion GO:0002790 114 0.215
Mouse
regulation of neuron differentiation GO:0045664 281 0.208
astrocyte fate commitment GO:0060018 4 0.198
telencephalon cell migration GO:0022029 55 0.194
Mouse
cation transport GO:0006812 399 0.188
Human Mouse
regulation of hormone secretion GO:0046883 88 0.184
Mouse
regulation of lymphocyte activation GO:0051249 240 0.184
positive regulation of secretion GO:0051047 130 0.184
Mouse
forebrain cell migration GO:0021885 58 0.184
Mouse
epithelial tube morphogenesis GO:0060562 303 0.180
cellular amine metabolic process GO:0044106 44 0.178
memory GO:0007613 58 0.175
Rat
stem cell differentiation GO:0048863 268 0.172
sperm motility GO:0030317 47 0.169
nitrogen compound transport GO:0071705 271 0.165
Mouse
regulation of b cell proliferation GO:0030888 39 0.165
response to light stimulus GO:0009416 135 0.162
Mouse Rat
response to organonitrogen compound GO:0010243 246 0.159
b cell activation GO:0042113 161 0.158
positive regulation of dopamine secretion GO:0033603 2 0.157
inflammatory response GO:0006954 244 0.156
cranial nerve development GO:0021545 41 0.156
regulation of response to wounding GO:1903034 189 0.151
regulation of cell activation GO:0050865 289 0.150
ribose phosphate biosynthetic process GO:0046390 59 0.147
Human
negative regulation of kinase activity GO:0033673 81 0.146
amine metabolic process GO:0009308 45 0.145
positive regulation of cell migration GO:0030335 109 0.144
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.144
leukocyte differentiation GO:0002521 342 0.142
positive regulation of secretion by cell GO:1903532 114 0.139
Mouse
negative regulation of transferase activity GO:0051348 85 0.138
positive regulation of transferase activity GO:0051347 167 0.137
Human
purine containing compound biosynthetic process GO:0072522 70 0.137
Human
retinal cone cell development GO:0046549 8 0.137
regulation of cell migration GO:0030334 219 0.137
Mouse
phenol containing compound metabolic process GO:0018958 60 0.136
regulation of neuron death GO:1901214 134 0.136
sensory perception of light stimulus GO:0050953 54 0.133
histamine induced gastric acid secretion GO:0001697 1 0.131
anatomical structure homeostasis GO:0060249 145 0.128
circadian rhythm GO:0007623 114 0.128
neural retina development GO:0003407 41 0.128
retina morphogenesis in camera type eye GO:0060042 45 0.127
spermatogenesis GO:0007283 284 0.125
regulation of mapk cascade GO:0043408 248 0.123
Human
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.122
negative regulation of phosphorus metabolic process GO:0010563 184 0.121
Human
cellular calcium ion homeostasis GO:0006874 119 0.120
generation of ovulation cycle rhythm GO:0060112 1 0.119
male gamete generation GO:0048232 285 0.119
myeloid leukocyte differentiation GO:0002573 119 0.118
central nervous system neuron differentiation GO:0021953 162 0.116
Zebrafish Mouse
transmembrane transport GO:0055085 412 0.116
Human
cilium morphogenesis GO:0060271 102 0.116
regulation of system process GO:0044057 200 0.115
Mouse
response to organic cyclic compound GO:0014070 198 0.115
regulation of leukocyte differentiation GO:1902105 159 0.115
gabaergic neuron differentiation GO:0097154 11 0.114
Mouse
central nervous system neuron development GO:0021954 67 0.113
Mouse
negative regulation of nervous system development GO:0051961 156 0.113
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.112
regulation of leukocyte proliferation GO:0070663 121 0.109
visual behavior GO:0007632 45 0.107
Mouse
metal ion homeostasis GO:0055065 189 0.107
Mouse
smooth muscle contraction GO:0006939 44 0.106
Mouse
skin development GO:0043588 220 0.106
negative regulation of lymphocyte activation GO:0051250 91 0.106
erk1 and erk2 cascade GO:0070371 77 0.104
norepinephrine transport GO:0015874 2 0.103
neuron apoptotic process GO:0051402 142 0.102
sensory perception GO:0007600 245 0.102
Mouse
ion transmembrane transport GO:0034220 361 0.101
Human
regulation of nucleotide metabolic process GO:0006140 169 0.101
Human
learning or memory GO:0007611 148 0.100
Mouse Rat
mapk cascade GO:0000165 281 0.100
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.098
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.098
axonogenesis GO:0007409 274 0.098
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.097
morphogenesis of embryonic epithelium GO:0016331 159 0.097
ear development GO:0043583 200 0.096
positive regulation of lymphocyte activation GO:0051251 140 0.096
purine nucleotide biosynthetic process GO:0006164 65 0.095
Human
regulation of inflammatory response GO:0050727 147 0.095
regulation of lipid transport GO:0032368 36 0.094
detection of external stimulus GO:0009581 61 0.093
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.093
transmission of nerve impulse GO:0019226 76 0.093
compound eye development GO:0048749 1 0.092
positive regulation of protein phosphorylation GO:0001934 242 0.090
Human
cell fate commitment GO:0045165 210 0.090
Zebrafish
regulation of defense response GO:0031347 233 0.090
organonitrogen compound biosynthetic process GO:1901566 192 0.089
Human
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.089
multicellular organismal signaling GO:0035637 91 0.089
regulation of camp metabolic process GO:0030814 30 0.089
Human
positive regulation of glycolytic process GO:0045821 4 0.088
substrate independent telencephalic tangential migration GO:0021826 8 0.087
Mouse
stem cell development GO:0048864 219 0.086
negative regulation of t cell activation GO:0050868 65 0.086
cerebral cortex neuron differentiation GO:0021895 19 0.086
Mouse
corticotropin releasing hormone secretion GO:0043396 2 0.085
positive regulation of cytokine production GO:0001819 174 0.084
eye photoreceptor cell development GO:0042462 31 0.084
ribonucleotide biosynthetic process GO:0009260 59 0.083
Human
regulation of camp biosynthetic process GO:0030817 25 0.083
Human
cell cell recognition GO:0009988 44 0.082
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.079
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.079
peptidyl tyrosine modification GO:0018212 145 0.078
calcium ion homeostasis GO:0055074 127 0.077
regulation of protein serine threonine kinase activity GO:0071900 157 0.077
Human
retina development in camera type eye GO:0060041 119 0.076
Rat
regulation of muscle contraction GO:0006937 49 0.076
acetylcholine transport GO:0015870 2 0.076
response to lipopolysaccharide GO:0032496 128 0.075
cellular response to lipid GO:0071396 145 0.075
activation of adenylate cyclase activity GO:0007190 4 0.075
synaptic transmission GO:0007268 329 0.074
catecholamine secretion GO:0050432 15 0.074
Mouse
regulation of chemotaxis GO:0050920 53 0.074
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.074
leukocyte apoptotic process GO:0071887 71 0.074
regulation of cysteine type endopeptidase activity GO:2000116 65 0.074
muscle system process GO:0003012 141 0.073
Mouse
positive regulation of programmed cell death GO:0043068 218 0.073
apoptotic signaling pathway GO:0097190 306 0.073
regulation of secretion GO:0051046 274 0.072
Human Mouse Rat
cellular ion homeostasis GO:0006873 165 0.072
norepinephrine secretion GO:0048243 2 0.072
neural precursor cell proliferation GO:0061351 121 0.072
Mouse
regulation of circadian sleep wake cycle GO:0042749 3 0.072
regulation of cell projection organization GO:0031344 206 0.071
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.071
Human
b cell proliferation GO:0042100 53 0.071
glial cell differentiation GO:0010001 131 0.070
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.070
embryonic skeletal system development GO:0048706 120 0.069
germ cell development GO:0007281 185 0.069
response to molecule of bacterial origin GO:0002237 143 0.068
positive regulation of protein modification process GO:0031401 299 0.068
Human
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.067
interneuron migration from the subpallium to the cortex GO:0021830 7 0.067
Mouse
cellular metal ion homeostasis GO:0006875 151 0.067
negative regulation of action potential GO:0045759 1 0.067
t cell activation GO:0042110 289 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
positive regulation of cell activation GO:0050867 158 0.066
sensitization GO:0046960 2 0.065
ras protein signal transduction GO:0007265 77 0.065
adult behavior GO:0030534 135 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.065
nucleoside phosphate biosynthetic process GO:1901293 79 0.065
Human
regulation of transmembrane transport GO:0034762 128 0.064
Human
regulation of feeding behavior GO:0060259 3 0.064
morphogenesis of a branching structure GO:0001763 203 0.064
Mouse
membrane depolarization GO:0051899 64 0.064
Rat
regionalization GO:0003002 337 0.064
g protein coupled receptor signaling pathway GO:0007186 243 0.064
cognition GO:0050890 149 0.063
Mouse Rat
cell maturation GO:0048469 127 0.062
regulation of action potential GO:0098900 4 0.062
cellular response to abiotic stimulus GO:0071214 56 0.062
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.061
forebrain generation of neurons GO:0021872 63 0.061
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.061
cellular amino acid metabolic process GO:0006520 103 0.061
phototransduction GO:0007602 17 0.061
neuronal action potential GO:0019228 54 0.060
regulation of cell cycle GO:0051726 281 0.060
embryonic camera type eye development GO:0031076 36 0.060
camp metabolic process GO:0046058 40 0.059
Human
regulation of b cell activation GO:0050864 81 0.059
regulation of cellular catabolic process GO:0031329 242 0.059
negative regulation of phosphate metabolic process GO:0045936 184 0.059
Human
divalent inorganic cation homeostasis GO:0072507 138 0.059
positive regulation of kinase activity GO:0033674 155 0.059
Human
catecholamine metabolic process GO:0006584 30 0.058
organelle fission GO:0048285 170 0.058
cellular divalent inorganic cation homeostasis GO:0072503 127 0.058
positive regulation of cell death GO:0010942 224 0.058
embryonic eye morphogenesis GO:0048048 29 0.058
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.057
optic nerve development GO:0021554 8 0.057
mesenchymal cell development GO:0014031 93 0.056
regulation of norepinephrine secretion GO:0014061 2 0.056
negative regulation of immune system process GO:0002683 209 0.056
positive regulation of cellular amine metabolic process GO:0033240 5 0.056
detection of abiotic stimulus GO:0009582 60 0.056
dna metabolic process GO:0006259 303 0.056
negative regulation of cell activation GO:0050866 111 0.055
positive regulation of blood circulation GO:1903524 22 0.055
nucleotide metabolic process GO:0009117 332 0.055
Human
response to drug GO:0042493 75 0.054
Mouse
positive regulation of nervous system development GO:0051962 221 0.054
Mouse
positive regulation of mapk cascade GO:0043410 170 0.054
Human
positive regulation of protein kinase activity GO:0045860 144 0.054
Human
t helper 17 cell chemotaxis GO:0035705 1 0.053
positive regulation of homeostatic process GO:0032846 64 0.053
Mouse
telencephalon development GO:0021537 186 0.053
Mouse
regulation of circadian rhythm GO:0042752 58 0.052
negative regulation of b cell activation GO:0050869 27 0.052
connective tissue development GO:0061448 179 0.052
membrane hyperpolarization GO:0060081 21 0.052
peptidyl tyrosine phosphorylation GO:0018108 143 0.052
diencephalon development GO:0021536 63 0.052
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.052
forebrain neuron development GO:0021884 30 0.052
Mouse
positive regulation of heart contraction GO:0045823 14 0.051
acetylcholine secretion neurotransmission GO:0014055 2 0.051
learning GO:0007612 98 0.051
Mouse Rat
adaptive immune response GO:0002250 155 0.051
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.051
regulation of purine nucleotide metabolic process GO:1900542 169 0.051
Human
skeletal system development GO:0001501 356 0.051
detection of stimulus GO:0051606 84 0.051
mitotic cell cycle GO:0000278 195 0.051
regulation of anion transport GO:0044070 27 0.051
erythrocyte differentiation GO:0030218 88 0.050
purine containing compound metabolic process GO:0072521 311 0.050
Human
rhythmic process GO:0048511 174 0.050
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.050
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.049
inorganic cation transmembrane transport GO:0098662 207 0.049
Human
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.049
microtubule cytoskeleton organization GO:0000226 157 0.049
cellular chemical homeostasis GO:0055082 215 0.049
regulation of blood circulation GO:1903522 93 0.049
Mouse
organophosphate biosynthetic process GO:0090407 122 0.049
Human
regulation of t cell activation GO:0050863 170 0.048
positive regulation of heart rate GO:0010460 10 0.048
nucleotide biosynthetic process GO:0009165 78 0.048
Human
multicellular organism growth GO:0035264 161 0.048
Mouse
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.047
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.047
protein localization to nucleus GO:0034504 121 0.047
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.047
Mouse
positive regulation of cell motility GO:2000147 116 0.046
cellular response to temperature stimulus GO:0071502 2 0.046
dendrite development GO:0016358 115 0.045
lymphocyte differentiation GO:0030098 242 0.045
regulation of erk1 and erk2 cascade GO:0070372 71 0.045
lymphocyte apoptotic process GO:0070227 54 0.045
tissue remodeling GO:0048771 102 0.045
detection of light stimulus GO:0009583 25 0.044
regulation of cytokine production GO:0001817 266 0.044
cell division GO:0051301 120 0.044
positive regulation of peptide secretion GO:0002793 33 0.044
Mouse
cellular ketone metabolic process GO:0042180 84 0.043
branching morphogenesis of an epithelial tube GO:0048754 159 0.043
kidney mesenchyme morphogenesis GO:0072131 4 0.043
purine ribonucleotide biosynthetic process GO:0009152 59 0.043
Human
blood vessel morphogenesis GO:0048514 285 0.043
divalent metal ion transport GO:0070838 172 0.043
Human
regulation of establishment of protein localization GO:0070201 181 0.043
Human
leukocyte proliferation GO:0070661 172 0.042
axon ensheathment GO:0008366 76 0.042
mitotic cell cycle process GO:1903047 159 0.042
hair follicle morphogenesis GO:0031069 29 0.042
myeloid leukocyte activation GO:0002274 83 0.042
visual learning GO:0008542 44 0.042
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.042
feeding behavior GO:0007631 62 0.042
Mouse
alpha beta t cell differentiation GO:0046632 69 0.041
body fluid secretion GO:0007589 53 0.041
mesenchyme development GO:0060485 152 0.041
asymmetric stem cell division GO:0098722 3 0.040
hepatocyte apoptotic process GO:0097284 11 0.040
circadian sleep wake cycle non rem sleep GO:0042748 2 0.040
chemotaxis GO:0006935 247 0.040
positive regulation of ion transport GO:0043270 65 0.040
Human Mouse
nucleocytoplasmic transport GO:0006913 139 0.040
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.040
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.040
Human
negative regulation of defense response GO:0031348 77 0.040
embryonic epithelial tube formation GO:0001838 130 0.040
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.040
negative regulation of leukocyte differentiation GO:1902106 51 0.039
nuclear transport GO:0051169 139 0.039
regulation of protein catabolic process GO:0042176 108 0.039
oligodendrocyte differentiation GO:0048709 53 0.039
Mouse
catecholamine transport GO:0051937 21 0.039
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.039
regulation of hydrolase activity GO:0051336 246 0.039
regulation of smooth muscle contraction GO:0006940 22 0.039
endocrine system development GO:0035270 98 0.039
Mouse
protein localization to organelle GO:0033365 185 0.038
detection of visible light GO:0009584 14 0.038
monoamine transport GO:0015844 33 0.038
Mouse
cgmp catabolic process GO:0046069 2 0.038
negative regulation of cell proliferation GO:0008285 296 0.038
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.038
lymphocyte proliferation GO:0046651 164 0.038
g protein coupled receptor internalization GO:0002031 3 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
Human
regulation of muscle system process GO:0090257 80 0.038
microtubule based process GO:0007017 236 0.037
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.037
carbohydrate metabolic process GO:0005975 230 0.036
embryonic organ morphogenesis GO:0048562 276 0.036
regulation of neuron projection development GO:0010975 169 0.036
cytokine production GO:0001816 319 0.036
rhodopsin mediated signaling pathway GO:0016056 4 0.036
photoreceptor cell differentiation GO:0046530 52 0.036
negative regulation of camp metabolic process GO:0030815 5 0.036
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.035
negative regulation of neuron differentiation GO:0045665 101 0.035
developmental maturation GO:0021700 193 0.035
peptidyl amino acid modification GO:0018193 336 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
pulmonary myocardium development GO:0003350 3 0.035
regulation of gliogenesis GO:0014013 50 0.035
Mouse
response to oxygen levels GO:0070482 62 0.035
establishment of protein localization to organelle GO:0072594 118 0.035
nuclear division GO:0000280 158 0.034
cerebral cortex cell migration GO:0021795 44 0.034
associative learning GO:0008306 61 0.034
Mouse Rat
posttranscriptional regulation of gene expression GO:0010608 155 0.034
axon guidance GO:0007411 141 0.034
small gtpase mediated signal transduction GO:0007264 97 0.034
regulation of glycolytic process GO:0006110 10 0.034
response to endoplasmic reticulum stress GO:0034976 53 0.034
photoreceptor cell development GO:0042461 40 0.034
heart process GO:0003015 94 0.034
Mouse
regulation of proteolysis GO:0030162 164 0.033
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.033
positive regulation of leukocyte proliferation GO:0070665 73 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.032
defense response to virus GO:0051607 68 0.032
peptide hormone secretion GO:0030072 109 0.032
Mouse
tube formation GO:0035148 140 0.032
cytoplasmic transport GO:0016482 234 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.032
Mouse
neuroblast differentiation GO:0014016 2 0.032
organic hydroxy compound transport GO:0015850 93 0.032
Mouse
adult locomotory behavior GO:0008344 91 0.032
cranial nerve morphogenesis GO:0021602 26 0.031
homeostasis of number of cells GO:0048872 210 0.031
negative regulation of phosphorylation GO:0042326 166 0.031
atrioventricular node cell development GO:0060928 2 0.031
developmental programmed cell death GO:0010623 41 0.031
regulation of vasculature development GO:1901342 88 0.031
negative regulation of cholesterol transport GO:0032375 4 0.031
hormone secretion GO:0046879 128 0.030
Mouse
response to cocaine GO:0042220 14 0.030
dopamine metabolic process GO:0042417 23 0.030
forebrain neuron fate commitment GO:0021877 13 0.030
gliogenesis GO:0042063 141 0.030
Mouse
bone resorption GO:0045453 38 0.030
subpallium neuron fate commitment GO:0060163 2 0.030
camp biosynthetic process GO:0006171 31 0.030
Human
positive regulation of camp biosynthetic process GO:0030819 19 0.029
negative regulation of secretion GO:0051048 61 0.029
Human
regulation of leukocyte apoptotic process GO:2000106 56 0.029
epithelial cell development GO:0002064 159 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
fat cell differentiation GO:0045444 160 0.029
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.029
lateral geniculate nucleus development GO:0021771 1 0.029
meiotic nuclear division GO:0007126 115 0.028
pallium development GO:0021543 120 0.028
response to alkaloid GO:0043279 34 0.028
multi organism reproductive behavior GO:0044705 29 0.028
regulation of peptide secretion GO:0002791 77 0.028
Mouse
brown fat cell differentiation GO:0050873 36 0.028
positive regulation of neuron apoptotic process GO:0043525 25 0.028
lens development in camera type eye GO:0002088 62 0.028
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.028
asymmetric neuroblast division GO:0055059 1 0.028
myeloid cell homeostasis GO:0002262 114 0.028
establishment of organelle localization GO:0051656 122 0.027
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.027
ensheathment of neurons GO:0007272 76 0.027
subpallium development GO:0021544 20 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
Human
divalent inorganic cation transport GO:0072511 178 0.027
Human
response to alcohol GO:0097305 48 0.027
Mouse
regulation of interleukin 12 production GO:0032655 30 0.027
spleen development GO:0048536 39 0.027
cyclic nucleotide mediated signaling GO:0019935 18 0.027
regulation of interleukin 1 alpha production GO:0032650 4 0.027
nephrogenic mesenchyme development GO:0072076 3 0.027
regulation of secretion by cell GO:1903530 249 0.027
Human Mouse Rat
fatty acid derivative transport GO:1901571 14 0.027
Human
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.027
sensory perception of mechanical stimulus GO:0050954 107 0.027
regulation of hormone levels GO:0010817 211 0.026
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.026
regulation of interleukin 1 production GO:0032652 26 0.026
immune effector process GO:0002252 321 0.026
positive regulation of peptide hormone secretion GO:0090277 31 0.026
Mouse
heart contraction GO:0060047 93 0.026
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.026
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.026
regulation of monocyte chemotaxis GO:0090025 3 0.026
regulation of t cell differentiation GO:0045580 83 0.026
response to transforming growth factor beta GO:0071559 88 0.026
regulation of interleukin 1 beta production GO:0032651 25 0.025
cellular response to molecule of bacterial origin GO:0071219 83 0.025
regulation of ossification GO:0030278 112 0.025
sodium ion transport GO:0006814 73 0.025
Human Mouse
cyclic purine nucleotide metabolic process GO:0052652 43 0.025
Human
response to extracellular stimulus GO:0009991 127 0.025
Worm
muscle tissue development GO:0060537 308 0.025
protein maturation GO:0051604 176 0.025
positive regulation of camp metabolic process GO:0030816 19 0.025
cerebral cortex development GO:0021987 86 0.025
cellular response to lipopolysaccharide GO:0071222 77 0.025
regulation of cell cycle process GO:0010564 160 0.025
limbic system development GO:0021761 72 0.025
single organism nuclear import GO:1902593 95 0.025
macromolecule catabolic process GO:0009057 281 0.025
neuron projection guidance GO:0097485 141 0.025
peptide transport GO:0015833 133 0.025
Mouse
negative regulation of cell growth GO:0030308 44 0.025
appendage morphogenesis GO:0035107 149 0.024
protein secretion GO:0009306 111 0.024
Human
negative regulation of inflammatory response GO:0050728 61 0.024
morphogenesis of a branching epithelium GO:0061138 193 0.024
regulation of innate immune response GO:0045088 91 0.024
positive regulation of defense response GO:0031349 124 0.024
synaptic transmission cholinergic GO:0007271 7 0.024
regulation of multi organism process GO:0043900 111 0.024
Rat
multi multicellular organism process GO:0044706 109 0.024
positive regulation of lymphocyte proliferation GO:0050671 70 0.024
intestinal epithelial structure maintenance GO:0060729 4 0.024
medial motor column neuron differentiation GO:0021526 2 0.024
tumor necrosis factor production GO:0032640 50 0.024
primary prostatic bud elongation GO:0060516 2 0.024
neural nucleus development GO:0048857 22 0.024
negative regulation of sterol transport GO:0032372 4 0.024
regulation of organelle organization GO:0033043 289 0.023
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback GO:0001978 5 0.023
b cell differentiation GO:0030183 78 0.023
t cell differentiation GO:0030217 174 0.023
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.023
Mouse
ameboidal type cell migration GO:0001667 128 0.023
somatostatin signaling pathway GO:0038170 2 0.023
organelle localization GO:0051640 179 0.023
cardiac muscle hypertrophy GO:0003300 23 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.023
Human
establishment or maintenance of cell polarity GO:0007163 86 0.023
glutamate receptor signaling pathway GO:0007215 35 0.023
regulation of phospholipase c activity GO:1900274 3 0.023
ventral spinal cord development GO:0021517 48 0.023
Zebrafish
monosaccharide transport GO:0015749 58 0.023
membrane organization GO:0061024 245 0.023
negative regulation of neuron death GO:1901215 98 0.023
positive regulation of neural precursor cell proliferation GO:2000179 42 0.023
Mouse
response to metal ion GO:0010038 47 0.022
positive regulation of hormone secretion GO:0046887 38 0.022
Mouse
negative regulation of cell development GO:0010721 169 0.022
Mouse
organelle assembly GO:0070925 177 0.022

Drd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.287
disease of anatomical entity DOID:7 0 0.287
eye and adnexa disease DOID:1492 0 0.287
nervous system disease DOID:863 0 0.287
retinal disease DOID:5679 0 0.194
retinal degeneration DOID:8466 0 0.194
retinitis pigmentosa DOID:10584 0 0.194
eye disease DOID:5614 0 0.194
mouth disease DOID:403 0 0.045
gastrointestinal system disease DOID:77 0 0.045