Mus musculus

253 known processes

Dvl1

dishevelled, dsh homolog 1 (Drosophila)

(Aliases: Dvl,mKIAA4029,KIAA4029)

Dvl1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.998
Mouse
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.995
Mouse
protein localization to microtubule cytoskeleton GO:0072698 8 0.991
cytoplasmic microtubule organization GO:0031122 14 0.985
jnk cascade GO:0007254 72 0.975
Mouse
muscular septum morphogenesis GO:0003150 4 0.971
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.964
establishment of monopolar cell polarity GO:0061162 8 0.958
Fly
planar dichotomous subdivision of terminal units involved in lung branching morphogenesis GO:0060489 2 0.957
convergent extension involved in axis elongation GO:0060028 7 0.946
protein localization to microtubule GO:0035372 3 0.943
planar cell polarity pathway involved in axis elongation GO:0003402 4 0.942
establishment of tissue polarity GO:0007164 28 0.933
regulation of establishment of planar polarity GO:0090175 28 0.923
stress activated mapk cascade GO:0051403 80 0.911
Mouse
regulation of stress activated mapk cascade GO:0032872 69 0.900
Mouse
embryonic epithelial tube formation GO:0001838 130 0.896
cardiac septum development GO:0003279 59 0.894
Mouse
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.886
Fly
neuron migration GO:0001764 122 0.883
Worm
dendrite self avoidance GO:0070593 2 0.878
establishment or maintenance of monopolar cell polarity GO:0061339 8 0.865
Fly
mapk cascade GO:0000165 281 0.863
Mouse
regulation of jnk cascade GO:0046328 62 0.848
Mouse
tube closure GO:0060606 91 0.841
ubiquitin dependent protein catabolic process GO:0006511 129 0.839
Human
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.833
Fly
regulation of cardiac cell fate specification GO:2000043 1 0.829
Fly
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.828
digestive tract morphogenesis GO:0048546 147 0.819
Worm
positive regulation of jun kinase activity GO:0043507 30 0.816
Mouse
non canonical wnt signaling pathway GO:0035567 33 0.814
convergent extension involved in neural plate elongation GO:0022007 4 0.813
regulation of microtubule based process GO:0032886 52 0.811
Mouse Worm
neural plate morphogenesis GO:0001839 9 0.803
establishment of planar polarity GO:0001736 28 0.801
neural tube formation GO:0001841 108 0.796
gonad morphogenesis GO:0035262 1 0.796
Worm
neural plate elongation GO:0014022 4 0.790
morphogenesis of a polarized epithelium GO:0001738 37 0.788
heart morphogenesis GO:0003007 178 0.785
Mouse Fly
ras protein signal transduction GO:0007265 77 0.780
regulation of organ morphogenesis GO:2000027 144 0.765
regulation of cardioblast differentiation GO:0051890 3 0.754
Fly
positive regulation of protein phosphorylation GO:0001934 242 0.753
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.747
regulation of cellular response to stress GO:0080135 159 0.743
Mouse
regionalization GO:0003002 337 0.742
Mouse Fly
protein catabolic process GO:0030163 221 0.741
Human
social behavior GO:0035176 21 0.738
epidermis development GO:0008544 187 0.735
Worm Fly
cellular ketone metabolic process GO:0042180 84 0.732
positive regulation of protein catabolic process GO:0045732 60 0.723
Human
negative regulation of phosphate metabolic process GO:0045936 184 0.718
cellular macromolecule catabolic process GO:0044265 206 0.713
Human
regulation of mapk cascade GO:0043408 248 0.704
Mouse
neurotransmitter secretion GO:0007269 62 0.702
morphogenesis of embryonic epithelium GO:0016331 159 0.696
actin cytoskeleton organization GO:0030036 220 0.691
Mouse Fly
negative regulation of phosphorylation GO:0042326 166 0.682
positive regulation of cellular amine metabolic process GO:0033240 5 0.681
heart induction GO:0003129 2 0.676
Fly
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.669
nonmotile primary cilium assembly GO:0035058 8 0.666
lateral sprouting involved in lung morphogenesis GO:0060490 2 0.663
hindbrain development GO:0030902 128 0.656
convergent extension involved in organogenesis GO:0060029 7 0.651
neural tube closure GO:0001843 90 0.645
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.645
Human
negative regulation of phosphorus metabolic process GO:0010563 184 0.636
lamellipodium organization GO:0097581 29 0.633
Fly
endodermal cell fate specification GO:0001714 4 0.629
Worm
cardiac cell fate specification GO:0060912 2 0.617
Fly
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.612
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.611
modification dependent macromolecule catabolic process GO:0043632 133 0.601
Human
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.590
neurotransmitter transport GO:0006836 76 0.583
epithelial tube formation GO:0072175 130 0.565
regulation of neurotransmitter levels GO:0001505 87 0.565
regulation of cellular amino acid metabolic process GO:0006521 5 0.560
cell fate commitment GO:0045165 210 0.548
Worm Fly
stress activated protein kinase signaling cascade GO:0031098 81 0.547
Mouse
regulation of map kinase activity GO:0043405 120 0.545
Mouse
positive regulation of protein modification process GO:0031401 299 0.539
canonical wnt signaling pathway GO:0060070 130 0.538
cardiac septum morphogenesis GO:0060411 46 0.534
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.530
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.529
regulation of neuron projection development GO:0010975 169 0.526
cellular amino acid metabolic process GO:0006520 103 0.510
cellular amine metabolic process GO:0044106 44 0.509
developmental cell growth GO:0048588 84 0.504
spindle localization GO:0051653 22 0.498
Worm
negative regulation of wnt signaling pathway GO:0030178 73 0.489
synapse organization GO:0050808 125 0.482
positive regulation of kinase activity GO:0033674 155 0.479
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.478
positive regulation of map kinase activity GO:0043406 84 0.473
Mouse
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.473
Human
tube formation GO:0035148 140 0.469
axis elongation GO:0003401 30 0.468
modification dependent protein catabolic process GO:0019941 133 0.463
Human
primary neural tube formation GO:0014020 95 0.457
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.453
digestive system development GO:0055123 200 0.446
Worm
segmentation GO:0035282 93 0.446
Mouse Fly
cell migration involved in kidney development GO:0035787 3 0.445
skin development GO:0043588 220 0.440
Worm Fly
regulation of actin filament based process GO:0032970 99 0.436
Mouse Fly
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.427
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.425
regulation of cytoskeleton organization GO:0051493 122 0.425
Mouse Worm Fly
epithelial tube morphogenesis GO:0060562 303 0.423
regulation of protein serine threonine kinase activity GO:0071900 157 0.419
Mouse
stem cell differentiation GO:0048863 268 0.417
Fly
wnt signaling pathway GO:0016055 188 0.415
regulation of neuron differentiation GO:0045664 281 0.412
ear morphogenesis GO:0042471 118 0.409
establishment of epithelial cell polarity GO:0090162 10 0.408
Fly
morphogenesis of an epithelial sheet GO:0002011 27 0.405
regulation of jun kinase activity GO:0043506 40 0.404
Mouse
cellular protein catabolic process GO:0044257 155 0.404
Human
positive regulation of jnk cascade GO:0046330 46 0.402
Mouse
regulation of heart induction GO:0090381 2 0.400
Fly
cardiac chamber morphogenesis GO:0003206 93 0.395
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.385
ventricular septum morphogenesis GO:0060412 27 0.385
neuron projection extension GO:1990138 64 0.377
positive regulation of stress activated mapk cascade GO:0032874 48 0.375
Mouse
ventricular septum development GO:0003281 42 0.369
regulation of stem cell differentiation GO:2000736 50 0.369
Fly
protein localization to membrane GO:0072657 108 0.367
protein ubiquitination GO:0016567 171 0.366
embryonic organ morphogenesis GO:0048562 276 0.365
regulation of cell cycle GO:0051726 281 0.365
Worm
establishment of organelle localization GO:0051656 122 0.364
Worm
muscle tissue morphogenesis GO:0060415 53 0.361
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.358
wound healing GO:0042060 157 0.347
negative regulation of stem cell differentiation GO:2000737 14 0.345
Fly
positive regulation of cellular catabolic process GO:0031331 148 0.342
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.339
inner ear receptor stereocilium organization GO:0060122 23 0.335
positive regulation of cell development GO:0010720 237 0.333
digestive tract development GO:0048565 190 0.331
Worm
regulation of defense response GO:0031347 233 0.331
macromolecule catabolic process GO:0009057 281 0.330
Human
positive regulation of protein kinase activity GO:0045860 144 0.330
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.328
regulation of cellular component biogenesis GO:0044087 181 0.328
Fly
skeletal muscle acetylcholine gated channel clustering GO:0071340 7 0.326
amine metabolic process GO:0009308 45 0.322
neural tube development GO:0021915 160 0.316
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.314
Human
positive regulation of cell projection organization GO:0031346 95 0.308
intraspecies interaction between organisms GO:0051703 21 0.306
positive regulation of wnt signaling pathway GO:0030177 45 0.303
peptidyl tyrosine phosphorylation GO:0018108 143 0.292
Mouse
microtubule based process GO:0007017 236 0.288
convergent extension GO:0060026 14 0.282
specification of organ identity GO:0010092 30 0.281
t cell anergy GO:0002870 4 0.280
stem cell development GO:0048864 219 0.276
Fly
regulation of lymphocyte anergy GO:0002911 4 0.274
microtubule cytoskeleton organization GO:0000226 157 0.267
dichotomous subdivision of terminal units involved in lung branching GO:0060448 3 0.266
somatic stem cell maintenance GO:0035019 47 0.263
Fly
cardiac chamber development GO:0003205 108 0.261
Mouse
stem cell maintenance GO:0019827 130 0.260
Fly
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.254
axonogenesis GO:0007409 274 0.245
positive regulation of neuron differentiation GO:0045666 141 0.244
respiratory system development GO:0060541 190 0.243
Fly
regulation of multi organism process GO:0043900 111 0.243
sensory organ morphogenesis GO:0090596 242 0.238
negative regulation of defense response GO:0031348 77 0.237
retinal ganglion cell axon guidance GO:0031290 18 0.237
Fly
heart field specification GO:0003128 6 0.236
regulation of protein catabolic process GO:0042176 108 0.235
Human
regulation of t cell anergy GO:0002667 4 0.234
positive regulation of nervous system development GO:0051962 221 0.234
protein modification by small protein removal GO:0070646 21 0.234
positive regulation of mapk cascade GO:0043410 170 0.233
Mouse
neuron recognition GO:0008038 25 0.231
Fly
axon guidance GO:0007411 141 0.226
inner ear morphogenesis GO:0042472 101 0.223
negative regulation of protein modification process GO:0031400 163 0.220
peptidyl serine modification GO:0018209 83 0.220
cell growth GO:0016049 130 0.220
ear development GO:0043583 200 0.219
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.217
protein modification by small protein conjugation GO:0032446 187 0.215
segment specification GO:0007379 15 0.214
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.214
negative regulation of intracellular signal transduction GO:1902532 167 0.213
organ induction GO:0001759 21 0.211
Fly
positive regulation of neuron projection development GO:0010976 79 0.208
negative regulation of protein metabolic process GO:0051248 282 0.208
cardiac ventricle development GO:0003231 83 0.208
organelle localization GO:0051640 179 0.208
Worm
protein modification by small protein conjugation or removal GO:0070647 207 0.207
gastrulation GO:0007369 116 0.206
Worm
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.202
Mouse
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.201
endodermal cell fate commitment GO:0001711 12 0.201
Worm
formation of primary germ layer GO:0001704 77 0.201
Worm
membrane organization GO:0061024 245 0.197
regulation of non canonical wnt signaling pathway GO:2000050 12 0.196
mechanoreceptor differentiation GO:0042490 67 0.195
establishment or maintenance of cell polarity GO:0007163 86 0.195
Worm Fly
lung development GO:0030324 164 0.193
regulation of cell cycle process GO:0010564 160 0.193
Worm
salivary gland development GO:0007431 37 0.192
Fly
cardiocyte differentiation GO:0035051 87 0.192
Fly
regulation of transferase activity GO:0051338 263 0.184
Human Mouse
development of primary female sexual characteristics GO:0046545 73 0.183
Fly
regulation of protein targeting GO:1903533 61 0.181
small gtpase mediated signal transduction GO:0007264 97 0.179
cell division GO:0051301 120 0.178
Mouse Worm
protein localization to organelle GO:0033365 185 0.176
apical protein localization GO:0045176 7 0.176
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.175
positive regulation of lymphocyte anergy GO:0002913 4 0.174
regulation of binding GO:0051098 111 0.173
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.172
negative regulation of cell fate specification GO:0009996 4 0.171
Fly
developmental growth involved in morphogenesis GO:0060560 138 0.170
actin filament organization GO:0007015 113 0.168
Fly
negative regulation of bmp signaling pathway GO:0030514 35 0.168
regulation of proteasomal protein catabolic process GO:0061136 46 0.166
Human
negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948 6 0.166
kidney morphogenesis GO:0060993 83 0.163
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.159
negative regulation of growth GO:0045926 99 0.159
actin filament bundle assembly GO:0051017 40 0.158
Fly
regulation of protein tyrosine kinase activity GO:0061097 17 0.158
Mouse
embryonic heart tube development GO:0035050 65 0.156
epidermis morphogenesis GO:0048730 33 0.154
Worm Fly
intracellular protein transport GO:0006886 204 0.153
peptidyl amino acid modification GO:0018193 336 0.152
Mouse
cytokine production GO:0001816 319 0.152
postsynaptic membrane organization GO:0001941 18 0.147
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.144
Fly
defense response to other organism GO:0098542 197 0.144
germ cell development GO:0007281 185 0.141
Fly
positive regulation of proteolysis GO:0045862 85 0.141
Human
establishment of mitotic spindle localization GO:0040001 12 0.140
Worm
membranous septum morphogenesis GO:0003149 6 0.139
regulation of cellular protein catabolic process GO:1903362 61 0.138
Human
regulation of actin cytoskeleton organization GO:0032956 84 0.137
Mouse Fly
protein polyubiquitination GO:0000209 33 0.137
protein import into nucleus GO:0006606 95 0.135
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.135
Mouse
dendrite development GO:0016358 115 0.130
lymphocyte anergy GO:0002249 4 0.128
regulation of system process GO:0044057 200 0.127
regulation of tight junction assembly GO:2000810 2 0.126
embryonic heart tube morphogenesis GO:0003143 51 0.126
metanephric mesenchyme morphogenesis GO:0072133 4 0.123
regulation of cell projection organization GO:0031344 206 0.121
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.120
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.118
Human
cell fate specification GO:0001708 72 0.117
Worm Fly
cell proliferation involved in heart valve morphogenesis GO:0003249 1 0.116
regulation of kinase activity GO:0043549 249 0.115
Human Mouse
chemotaxis GO:0006935 247 0.114
mitotic cell cycle process GO:1903047 159 0.113
Worm
negative chemotaxis GO:0050919 14 0.112
Fly
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.112
genitalia development GO:0048806 37 0.112
Worm
striated muscle tissue development GO:0014706 293 0.112
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.111
regulation of cytoplasmic transport GO:1903649 112 0.110
regulation of establishment or maintenance of cell polarity GO:0032878 10 0.110
Worm
gonad development GO:0008406 141 0.109
Worm Fly
protein localization to cytoskeleton GO:0044380 9 0.109
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.108
morphogenesis of a branching structure GO:0001763 203 0.107
neuron projection guidance GO:0097485 141 0.107
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.106
negative regulation of notch signaling pathway GO:0045746 14 0.105
Fly
regulation of protein import into nucleus GO:0042306 52 0.105
post anal tail morphogenesis GO:0036342 23 0.105
determination of heart left right asymmetry GO:0061371 48 0.104
neuromuscular process GO:0050905 99 0.103
regulation of organelle organization GO:0033043 289 0.102
Mouse Worm Fly
negative regulation of lymphocyte activation GO:0051250 91 0.100
regulation of cation channel activity GO:2001257 22 0.100
regulation of synapse assembly GO:0051963 29 0.100
negative regulation of cellular amine metabolic process GO:0033239 1 0.100
regulation of protein localization GO:0032880 231 0.098
Worm
negative regulation of cell proliferation GO:0008285 296 0.098
positive regulation of t cell anergy GO:0002669 4 0.098
glycosyl compound metabolic process GO:1901657 246 0.096
regulation of microtubule cytoskeleton organization GO:0070507 37 0.096
Mouse Worm
female gamete generation GO:0007292 74 0.096
Fly
muscle system process GO:0003012 141 0.096
regulation of embryonic development GO:0045995 71 0.096
negative regulation of cell activation GO:0050866 111 0.095
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.094
establishment of spindle orientation GO:0051294 15 0.093
Worm
regulation of muscle system process GO:0090257 80 0.092
protein targeting GO:0006605 143 0.092
lymphocyte proliferation GO:0046651 164 0.092
regulation of cellular catabolic process GO:0031329 242 0.091
Human
oogenesis GO:0048477 56 0.091
Fly
regulation of transmembrane transport GO:0034762 128 0.091
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.089
Worm
positive regulation of transferase activity GO:0051347 167 0.088
Mouse
cell recognition GO:0008037 83 0.088
Fly
regulation of actin filament bundle assembly GO:0032231 18 0.088
Fly
negative regulation of molecular function GO:0044092 258 0.087
Human
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.087
regulation of protein kinase activity GO:0045859 232 0.086
Human Mouse
regulation of intracellular protein transport GO:0033157 82 0.084
development of primary sexual characteristics GO:0045137 143 0.084
Worm Fly
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.084
regulation of ion transmembrane transporter activity GO:0032412 54 0.084
regulation of heart morphogenesis GO:2000826 22 0.083
Fly
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.083
positive regulation of cell adhesion GO:0045785 80 0.083
cellular response to growth factor stimulus GO:0071363 197 0.082
neural plate development GO:0001840 12 0.082
negative regulation of peptidyl threonine phosphorylation GO:0010801 6 0.082
kidney development GO:0001822 213 0.081
regulation of mitotic cell cycle GO:0007346 126 0.081
Worm
proteasomal protein catabolic process GO:0010498 98 0.080
Human
alpha beta t cell activation GO:0046631 91 0.079
regulation of neuron death GO:1901214 134 0.078
cell fate determination GO:0001709 32 0.078
Worm
renal system development GO:0072001 225 0.077
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.077
p38mapk cascade GO:0038066 4 0.077
regulation of bmp signaling pathway GO:0030510 60 0.076
skeletal system development GO:0001501 356 0.074
mitotic cell cycle GO:0000278 195 0.074
Worm
lung morphogenesis GO:0060425 50 0.074
negative regulation of systemic arterial blood pressure GO:0003085 15 0.073
peptidyl tyrosine modification GO:0018212 145 0.073
Mouse
female gonad development GO:0008585 71 0.073
Fly
multi multicellular organism process GO:0044706 109 0.072
Worm
cellular response to dna damage stimulus GO:0006974 207 0.072
regulation of notch signaling pathway GO:0008593 35 0.071
Fly
establishment of spindle localization GO:0051293 19 0.071
Worm
transmembrane transport GO:0055085 412 0.071
peptidyl threonine modification GO:0018210 31 0.071
regulation of lymphocyte activation GO:0051249 240 0.070
establishment of body hair planar orientation GO:0048105 2 0.069
filopodium assembly GO:0046847 19 0.069
Fly
nucleoside triphosphate metabolic process GO:0009141 230 0.069
cellular nitrogen compound catabolic process GO:0044270 280 0.068
oocyte construction GO:0007308 2 0.067
adaptive immune response GO:0002250 155 0.067
asymmetric cell division GO:0008356 8 0.067
Worm
neuron death GO:0070997 154 0.066
regulation of peptidyl serine phosphorylation GO:0033135 39 0.065
nephrogenic mesenchyme development GO:0072076 3 0.065
cell adhesion GO:0007155 329 0.065
regulation of lymphocyte proliferation GO:0050670 117 0.065
respiratory tube development GO:0030323 167 0.065
response to organonitrogen compound GO:0010243 246 0.064
cardiac muscle tissue development GO:0048738 130 0.061
negative regulation of protein phosphorylation GO:0001933 126 0.061
salivary gland morphogenesis GO:0007435 33 0.061
Fly
protein deubiquitination GO:0016579 19 0.059
regulation of nucleotide metabolic process GO:0006140 169 0.059
regulation of t cell activation GO:0050863 170 0.058
extracellular matrix organization GO:0030198 147 0.058
positive regulation of cellular protein catabolic process GO:1903364 34 0.058
Human
stem cell division GO:0017145 30 0.058
ossification GO:0001503 216 0.058
wnt signaling pathway involved in heart development GO:0003306 8 0.057
Fly
ribonucleotide metabolic process GO:0009259 291 0.057
cytoplasmic transport GO:0016482 234 0.057
cartilage development GO:0051216 140 0.057
cell fate commitment involved in pattern specification GO:0060581 14 0.057
Worm
rhythmic process GO:0048511 174 0.056
mesenchyme development GO:0060485 152 0.056
negative regulation of immune system process GO:0002683 209 0.055
cell proliferation involved in heart valve development GO:2000793 2 0.055
blood circulation GO:0008015 195 0.055
establishment of protein localization to organelle GO:0072594 118 0.054
ribonucleoside triphosphate metabolic process GO:0009199 220 0.053
metencephalon development GO:0022037 89 0.053
cell junction organization GO:0034330 77 0.052
glomerulus development GO:0032835 40 0.052
endodermal cell differentiation GO:0035987 14 0.052
Worm
regulation of nucleocytoplasmic transport GO:0046822 73 0.052
circulatory system process GO:0003013 197 0.051
regulation of cell fate commitment GO:0010453 19 0.051
Fly
regulation of protein localization to nucleus GO:1900180 60 0.051
positive regulation of programmed cell death GO:0043068 218 0.051
cochlea morphogenesis GO:0090103 22 0.051
protein localization to nucleus GO:0034504 121 0.050
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.050
cellular homeostasis GO:0019725 240 0.050
nucleotide catabolic process GO:0009166 217 0.050
cochlea development GO:0090102 35 0.050
gland development GO:0048732 330 0.049
Fly
negative regulation of leukocyte proliferation GO:0070664 46 0.049
positive regulation of ion transport GO:0043270 65 0.049
regulation of smad protein import into nucleus GO:0060390 3 0.049
regulation of purine nucleotide metabolic process GO:1900542 169 0.049
regulation of cell adhesion GO:0030155 154 0.049
determination of left right symmetry GO:0007368 80 0.049
regulation of body fluid levels GO:0050878 162 0.048
neuron apoptotic process GO:0051402 142 0.048
skeletal system morphogenesis GO:0048705 203 0.048
negative regulation of immune effector process GO:0002698 55 0.048
regulation of nucleotide catabolic process GO:0030811 122 0.047
regulation of fat cell differentiation GO:0045598 81 0.047
fat cell differentiation GO:0045444 160 0.047
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.047
establishment of apical basal cell polarity GO:0035089 7 0.046
Fly
cardiac muscle contraction GO:0060048 32 0.046
regulation of ion transport GO:0043269 215 0.046
female sex differentiation GO:0046660 84 0.046
Fly
negative regulation of multi organism process GO:0043901 68 0.045
cation transport GO:0006812 399 0.045
kidney mesenchyme morphogenesis GO:0072131 4 0.045
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.045
positive regulation of transmembrane transport GO:0034764 29 0.045
cilium morphogenesis GO:0060271 102 0.045
defense response to virus GO:0051607 68 0.044
regulation of circadian rhythm GO:0042752 58 0.044
hormone secretion GO:0046879 128 0.044
regulation of cytokine production GO:0001817 266 0.044
response to transforming growth factor beta GO:0071559 88 0.044
cell migration in hindbrain GO:0021535 16 0.044
protein oligomerization GO:0051259 67 0.043
organic cyclic compound catabolic process GO:1901361 295 0.043
purine nucleotide catabolic process GO:0006195 211 0.043
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.043
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.043
Human
muscle tissue development GO:0060537 308 0.042
outflow tract septum morphogenesis GO:0003148 11 0.042
Mouse
gtp catabolic process GO:0006184 143 0.042
myeloid cell homeostasis GO:0002262 114 0.042
regulation of cellular response to growth factor stimulus GO:0090287 82 0.041
peptidyl serine phosphorylation GO:0018105 74 0.041
glycosyl compound catabolic process GO:1901658 206 0.041
nucleoside catabolic process GO:0009164 206 0.041
cell fate specification involved in pattern specification GO:0060573 11 0.041
Worm
regulation of ral gtpase activity GO:0032315 4 0.041
peptidyl threonine phosphorylation GO:0018107 31 0.041
positive regulation of sodium ion transport GO:0010765 13 0.040
nucleocytoplasmic transport GO:0006913 139 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
muscle contraction GO:0006936 101 0.040
regulation of epithelial to mesenchymal transition GO:0010717 22 0.039
cell junction maintenance GO:0034331 4 0.039
negative regulation of blood pressure GO:0045776 22 0.039
protein import GO:0017038 101 0.038
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.038
synaptic growth at neuromuscular junction GO:0051124 6 0.038
regulation of protein deubiquitination GO:0090085 1 0.038
negative regulation of alpha beta t cell activation GO:0046636 18 0.038
regulation of cell growth GO:0001558 91 0.038
cell junction assembly GO:0034329 52 0.038
embryonic skeletal system development GO:0048706 120 0.037
meiotic cell cycle GO:0051321 122 0.037
nucleotide metabolic process GO:0009117 332 0.037
somitogenesis GO:0001756 69 0.037
outflow tract morphogenesis GO:0003151 53 0.037
Mouse
regulation of transporter activity GO:0032409 57 0.036
developmental induction GO:0031128 34 0.036
Fly
connective tissue development GO:0061448 179 0.036
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.035
regulation of cell activation GO:0050865 289 0.035
regulation of cell proliferation involved in heart valve morphogenesis GO:0003250 1 0.035
positive regulation of protein ubiquitination GO:0031398 27 0.035
negative regulation of osteoblast proliferation GO:0033689 4 0.035
regulation of systemic arterial blood pressure GO:0003073 61 0.035
asymmetric protein localization GO:0008105 11 0.035
Worm
heterocycle catabolic process GO:0046700 280 0.035
single organism nuclear import GO:1902593 95 0.034
regulation of intracellular transport GO:0032386 159 0.034
regulation of inflammatory response GO:0050727 147 0.034
positive regulation of gtp catabolic process GO:0033126 85 0.034
negative regulation of t cell activation GO:0050868 65 0.034
ribonucleotide catabolic process GO:0009261 208 0.034
regulation of blood pressure GO:0008217 93 0.034
purine nucleoside metabolic process GO:0042278 241 0.034
regulation of cell fate specification GO:0042659 10 0.033
Fly
carbohydrate derivative catabolic process GO:1901136 231 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
hindgut morphogenesis GO:0007442 7 0.033
habituation GO:0046959 3 0.033
camera type eye development GO:0043010 266 0.033
regulation of ossification GO:0030278 112 0.032
establishment of body hair or bristle planar orientation GO:0048104 2 0.032
negative regulation of sodium ion transport GO:0010766 4 0.032
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.032
regulation of establishment of protein localization GO:0070201 181 0.032
notch signaling pathway GO:0007219 71 0.032
Fly

Dvl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
disease of cellular proliferation DOID:14566 0 0.034