Mus musculus

119 known processes

Dyrk1a

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a

(Aliases: D16Ertd272e,Mnbh,Dyrk,Gm10783,D16Ertd493e,ENSMUSG00000074897,2310043O08Rik,MGC150253,mmb,MGC150254,Mp86)

Dyrk1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.806
cellular protein catabolic process GO:0044257 155 0.686
modification dependent macromolecule catabolic process GO:0043632 133 0.585
proteasomal protein catabolic process GO:0010498 98 0.503
cellular macromolecule catabolic process GO:0044265 206 0.460
modification dependent protein catabolic process GO:0019941 133 0.440
protein modification by small protein conjugation or removal GO:0070647 207 0.346
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.327
protein catabolic process GO:0030163 221 0.307
ubiquitin dependent protein catabolic process GO:0006511 129 0.306
macromolecule catabolic process GO:0009057 281 0.280
organelle fission GO:0048285 170 0.278
organelle assembly GO:0070925 177 0.246
rhythmic process GO:0048511 174 0.205
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.196
meiotic cell cycle GO:0051321 122 0.182
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.172
protein ubiquitination GO:0016567 171 0.171
regulation of organelle organization GO:0033043 289 0.170
histone modification GO:0016570 159 0.148
regulation of cell cycle GO:0051726 281 0.147
mitotic cell cycle GO:0000278 195 0.135
blastocyst development GO:0001824 80 0.122
protein modification by small protein conjugation GO:0032446 187 0.120
cellular amine metabolic process GO:0044106 44 0.108
protein polyubiquitination GO:0000209 33 0.105
apoptotic signaling pathway GO:0097190 306 0.104
negative regulation of cellular amine metabolic process GO:0033239 1 0.102
regionalization GO:0003002 337 0.099
regulation of intracellular transport GO:0032386 159 0.093
peptidyl amino acid modification GO:0018193 336 0.093
compound eye development GO:0048749 1 0.090
rna 3 end processing GO:0031123 20 0.087
regulation of cellular catabolic process GO:0031329 242 0.087
ras protein signal transduction GO:0007265 77 0.086
cellular nitrogen compound catabolic process GO:0044270 280 0.085
spermatogenesis GO:0007283 284 0.084
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.084
cellular response to dna damage stimulus GO:0006974 207 0.084
establishment of organelle localization GO:0051656 122 0.081
response to oxidative stress GO:0006979 123 0.081
regulation of cellular ketone metabolic process GO:0010565 66 0.077
germ cell development GO:0007281 185 0.077
membrane organization GO:0061024 245 0.076
ribonucleoside triphosphate catabolic process GO:0009203 199 0.075
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.075
olfactory learning GO:0008355 2 0.071
chromatin modification GO:0016568 187 0.071
cellular lipid metabolic process GO:0044255 323 0.071
dephosphorylation GO:0016311 129 0.071
regulation of proteasomal protein catabolic process GO:0061136 46 0.068
regulation of apoptotic signaling pathway GO:2001233 197 0.065
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.064
regulation of protein transport GO:0051223 163 0.064
positive regulation of apoptotic signaling pathway GO:2001235 95 0.063
nuclear division GO:0000280 158 0.063
organelle localization GO:0051640 179 0.062
regulation of cell cycle process GO:0010564 160 0.060
cellular response to organonitrogen compound GO:0071417 145 0.059
regulation of cellular protein catabolic process GO:1903362 61 0.057
meiotic nuclear division GO:0007126 115 0.057
positive regulation of programmed cell death GO:0043068 218 0.056
regulation of protein catabolic process GO:0042176 108 0.056
positive regulation of cellular catabolic process GO:0031331 148 0.054
positive regulation of proteolysis GO:0045862 85 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
organophosphate catabolic process GO:0046434 232 0.052
cell fate commitment GO:0045165 210 0.052
intrinsic apoptotic signaling pathway GO:0097193 132 0.051
regulation of hydrolase activity GO:0051336 246 0.051
regulation of cellular amine metabolic process GO:0033238 20 0.051
purine nucleotide catabolic process GO:0006195 211 0.051
mitotic cell cycle process GO:1903047 159 0.051
developmental cell growth GO:0048588 84 0.051
heterocycle catabolic process GO:0046700 280 0.051
central nervous system projection neuron axonogenesis GO:0021952 21 0.050
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.050
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.050
response to peptide GO:1901652 136 0.049
positive regulation of organelle organization GO:0010638 128 0.049
negative regulation of phosphate metabolic process GO:0045936 184 0.047
meiosis i GO:0007127 60 0.046
regulation of cellular response to stress GO:0080135 159 0.045
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.044
response to molecule of bacterial origin GO:0002237 143 0.043
gtp catabolic process GO:0006184 143 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.043
ribonucleoside metabolic process GO:0009119 245 0.043
male gamete generation GO:0048232 285 0.043
positive regulation of protein modification process GO:0031401 299 0.043
gtp metabolic process GO:0046039 144 0.043
regulation of chromatin silencing GO:0031935 2 0.042
forebrain development GO:0030900 302 0.042
cytoplasmic transport GO:0016482 234 0.041
negative regulation of cellular component organization GO:0051129 194 0.041
regulation of cellular component biogenesis GO:0044087 181 0.041
gland development GO:0048732 330 0.041
multicellular organism growth GO:0035264 161 0.041
negative regulation of cell cycle GO:0045786 123 0.041
regulation of adaptive immune response GO:0002819 90 0.041
response to organonitrogen compound GO:0010243 246 0.040
positive regulation of macroautophagy GO:0016239 3 0.040
skeletal muscle fiber development GO:0048741 58 0.040
muscle fiber development GO:0048747 76 0.040
regulation of cytoplasmic transport GO:1903649 112 0.040
ribose phosphate metabolic process GO:0019693 291 0.039
regulation of protein kinase activity GO:0045859 232 0.039
meiotic cell cycle process GO:1903046 77 0.039
regulation of mrna 3 end processing GO:0031440 6 0.039
negative regulation of protein metabolic process GO:0051248 282 0.039
cellular response to molecule of bacterial origin GO:0071219 83 0.038
purine containing compound metabolic process GO:0072521 311 0.038
muscle cell differentiation GO:0042692 261 0.038
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.038
developmental growth involved in morphogenesis GO:0060560 138 0.038
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.038
positive regulation of cell cycle GO:0045787 92 0.037
regulation of proteolysis GO:0030162 164 0.037
locomotory behavior GO:0007626 195 0.037
regulation of intracellular protein transport GO:0033157 82 0.037
regulation of neuron projection development GO:0010975 169 0.037
circadian rhythm GO:0007623 114 0.037
regulation of protein complex assembly GO:0043254 83 0.037
cellular response to insulin stimulus GO:0032869 78 0.037
nucleotide metabolic process GO:0009117 332 0.036
ribonucleoside catabolic process GO:0042454 206 0.036
muscle tissue development GO:0060537 308 0.036
cellular response to hormone stimulus GO:0032870 150 0.036
long term memory GO:0007616 15 0.036
defense response to other organism GO:0098542 197 0.036
amine metabolic process GO:0009308 45 0.036
cellular response to peptide hormone stimulus GO:0071375 92 0.036
positive regulation of protein phosphorylation GO:0001934 242 0.035
regulation of cell growth GO:0001558 91 0.035
negative regulation of nervous system development GO:0051961 156 0.035
phagocytosis GO:0006909 66 0.035
cellularization GO:0007349 1 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
response to insulin GO:0032868 100 0.034
mitochondrion organization GO:0007005 134 0.034
cation transport GO:0006812 399 0.034
memory GO:0007613 58 0.034
aromatic compound catabolic process GO:0019439 286 0.034
neural tube development GO:0021915 160 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.034
protein targeting GO:0006605 143 0.034
epithelial cell development GO:0002064 159 0.033
cellular ketone metabolic process GO:0042180 84 0.033
guanosine containing compound catabolic process GO:1901069 144 0.033
striated muscle cell development GO:0055002 125 0.033
cellular response to peptide GO:1901653 92 0.033
regulation of kinase activity GO:0043549 249 0.033
connective tissue development GO:0061448 179 0.033
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
response to lipopolysaccharide GO:0032496 128 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.032
actomyosin structure organization GO:0031032 56 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
neuron projection guidance GO:0097485 141 0.032
myeloid cell differentiation GO:0030099 233 0.032
Mouse
purine nucleotide metabolic process GO:0006163 302 0.031
covalent chromatin modification GO:0016569 163 0.031
intracellular protein transport GO:0006886 204 0.031
learning or memory GO:0007611 148 0.031
cell division GO:0051301 120 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
microtubule based process GO:0007017 236 0.030
regulation of response to wounding GO:1903034 189 0.030
rna processing GO:0006396 105 0.030
microtubule polymerization or depolymerization GO:0031109 26 0.030
ribonucleotide catabolic process GO:0009261 208 0.029
rna interference GO:0016246 2 0.029
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
t cell activation GO:0042110 289 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
protein acylation GO:0043543 64 0.029
purine containing compound catabolic process GO:0072523 213 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
gastrulation GO:0007369 116 0.029
digestive tract morphogenesis GO:0048546 147 0.029
erythrocyte differentiation GO:0030218 88 0.028
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.028
regulation of protein localization GO:0032880 231 0.028
regulation of mitotic cell cycle phase transition GO:1901990 73 0.028
cellular response to organic cyclic compound GO:0071407 87 0.028
negative regulation of synapse assembly GO:0051964 3 0.028
regulation of leukocyte differentiation GO:1902105 159 0.028
response to peptide hormone GO:0043434 127 0.028
positive regulation of interleukin 5 secretion GO:2000664 1 0.028
regulation of cell size GO:0008361 72 0.027
positive regulation of tor signaling GO:0032008 3 0.027
mitochondrion distribution GO:0048311 4 0.027
regulation of cellular component size GO:0032535 121 0.027
signal transduction by p53 class mediator GO:0072331 51 0.027
regulation of protein stability GO:0031647 52 0.027
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.027
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.027
regulation of wnt signaling pathway GO:0030111 123 0.027
nucleoside metabolic process GO:0009116 246 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
female gonad development GO:0008585 71 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
regulation of interleukin 10 secretion GO:2001179 4 0.026
spermatid development GO:0007286 108 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
engulfment of apoptotic cell GO:0043652 3 0.026
regulation of cell activation GO:0050865 289 0.026
regulation of system process GO:0044057 200 0.026
regulation of chromosome organization GO:0033044 83 0.025
male meiosis i GO:0007141 16 0.025
maintenance of apical basal cell polarity GO:0035090 3 0.025
positive regulation of protein transport GO:0051222 93 0.025
positive regulation of chromosome segregation GO:0051984 4 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
sensory organ morphogenesis GO:0090596 242 0.025
fat cell differentiation GO:0045444 160 0.025
embryonic organ morphogenesis GO:0048562 276 0.025
positive regulation of cellular protein catabolic process GO:1903364 34 0.025
regulation of binding GO:0051098 111 0.025
negative regulation of response to wounding GO:1903035 77 0.024
female gamete generation GO:0007292 74 0.024
endomembrane system organization GO:0010256 147 0.024
positive regulation of cell activation GO:0050867 158 0.024
innate immune response GO:0045087 157 0.024
oocyte anterior posterior axis specification GO:0007314 2 0.024
nucleotide catabolic process GO:0009166 217 0.024
regulation of nucleocytoplasmic transport GO:0046822 73 0.024
positive regulation of dna templated transcription elongation GO:0032786 2 0.024
bone development GO:0060348 120 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
nucleoside catabolic process GO:0009164 206 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
negative regulation of protein modification process GO:0031400 163 0.024
response to acid chemical GO:0001101 111 0.024
inflammatory response GO:0006954 244 0.024
syncytium formation by plasma membrane fusion GO:0000768 42 0.024
Mouse
regulation of neuron differentiation GO:0045664 281 0.024
organ growth GO:0035265 117 0.024
regulation of jnk cascade GO:0046328 62 0.023
respiratory system development GO:0060541 190 0.023
establishment or maintenance of cell polarity GO:0007163 86 0.023
dna metabolic process GO:0006259 303 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
oxidation reduction process GO:0055114 342 0.023
t cell proliferation GO:0042098 120 0.023
striated muscle tissue development GO:0014706 293 0.023
single organism cell adhesion GO:0098602 156 0.023
oocyte axis specification GO:0007309 2 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
camera type eye development GO:0043010 266 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
regulation of cytokine production GO:0001817 266 0.023
cognition GO:0050890 149 0.022
regulation of mitosis GO:0007088 29 0.022
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.022
regulation of insulin receptor signaling pathway GO:0046626 21 0.022
fertilization GO:0009566 127 0.022
protein depolymerization GO:0051261 34 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
regulation of response to dna damage stimulus GO:2001020 34 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
trophectodermal cellular morphogenesis GO:0001831 3 0.022
negative regulation of organelle organization GO:0010639 90 0.022
lipid biosynthetic process GO:0008610 179 0.022
homeostasis of number of cells GO:0048872 210 0.022
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
regulation of transferase activity GO:0051338 263 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
regulation of fat cell differentiation GO:0045598 81 0.021
chromosome segregation GO:0007059 48 0.021
actin cytoskeleton organization GO:0030036 220 0.021
digestive tract development GO:0048565 190 0.021
muscle cell development GO:0055001 133 0.021
dna endoreduplication GO:0042023 4 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
mrna processing GO:0006397 63 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
multi multicellular organism process GO:0044706 109 0.021
lung development GO:0030324 164 0.021
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.020
heart contraction GO:0060047 93 0.020
negative regulation of neuron differentiation GO:0045665 101 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
regulation of anatomical structure size GO:0090066 178 0.020
neuron projection extension GO:1990138 64 0.020
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.020
regulation of actin cytoskeleton organization GO:0032956 84 0.020
multi organism behavior GO:0051705 62 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
thermosensory behavior GO:0040040 1 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.020
nuclear transport GO:0051169 139 0.020
negative regulation of kinase activity GO:0033673 81 0.020
peptidyl lysine modification GO:0018205 77 0.020
regulation of dna dependent dna replication GO:0090329 8 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
mesodermal cell migration GO:0008078 4 0.019
regulation of nuclear division GO:0051783 56 0.019
establishment of vesicle localization GO:0051650 81 0.019
midgut development GO:0007494 4 0.019
positive regulation of cell development GO:0010720 237 0.019
glycerolipid metabolic process GO:0046486 122 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
regulation of blood circulation GO:1903522 93 0.019
oocyte construction GO:0007308 2 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
axonogenesis GO:0007409 274 0.019
chromatin organization GO:0006325 206 0.019
regulation of cellular response to insulin stimulus GO:1900076 30 0.019
regulation of mrna polyadenylation GO:1900363 1 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
peptidyl threonine modification GO:0018210 31 0.019
spindle assembly involved in mitosis GO:0090307 4 0.019
blood circulation GO:0008015 195 0.019
neuron migration GO:0001764 122 0.019
cell growth GO:0016049 130 0.019
pole plasm assembly GO:0007315 2 0.019
lymphocyte proliferation GO:0046651 164 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
stem cell differentiation GO:0048863 268 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
leukocyte proliferation GO:0070661 172 0.018
spongiotrophoblast layer development GO:0060712 15 0.018
cell fate determination GO:0001709 32 0.018
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.018
regulation of cell projection organization GO:0031344 206 0.018
neuronal action potential GO:0019228 54 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
protein secretion GO:0009306 111 0.018
embryonic placenta development GO:0001892 98 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
myotube differentiation GO:0014902 105 0.018
Mouse
positive regulation of nervous system development GO:0051962 221 0.018
metaphase plate congression GO:0051310 2 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
wnt signaling pathway GO:0016055 188 0.018
labyrinthine layer development GO:0060711 49 0.018
adult behavior GO:0030534 135 0.018
negative regulation of molecular function GO:0044092 258 0.018
mapk cascade GO:0000165 281 0.018
positive regulation of wnt signaling pathway GO:0030177 45 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
negative regulation of immune system process GO:0002683 209 0.017
plasma membrane organization GO:0007009 90 0.017
fourth ventricle development GO:0021592 2 0.017
cell cycle switching GO:0060184 1 0.017
oogenesis GO:0048477 56 0.017
maintenance of location GO:0051235 89 0.017
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.017
regulation of ral gtpase activity GO:0032315 4 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
neuron death GO:0070997 154 0.017
dna integrity checkpoint GO:0031570 28 0.017
regulation of interleukin 13 secretion GO:2000665 2 0.017
labyrinthine layer blood vessel development GO:0060716 21 0.017
response to parathyroid hormone GO:0071107 3 0.017
single organism nuclear import GO:1902593 95 0.017
placenta development GO:0001890 140 0.017
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.017
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.017
asymmetric neuroblast division GO:0055059 1 0.017
neural tube formation GO:0001841 108 0.017
cell type specific apoptotic process GO:0097285 268 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
protein maturation GO:0051604 176 0.016
protein polymerization GO:0051258 57 0.016
cellular protein complex disassembly GO:0043624 36 0.016
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.016
lateral inhibition GO:0046331 1 0.016
lipid homeostasis GO:0055088 63 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
positive regulation of growth GO:0045927 104 0.016
ventral midline development GO:0007418 4 0.016
learning GO:0007612 98 0.016
neural tube closure GO:0001843 90 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
development of primary sexual characteristics GO:0045137 143 0.016
primary neural tube formation GO:0014020 95 0.016
response to transforming growth factor beta GO:0071559 88 0.016
cellular protein complex assembly GO:0043623 116 0.016
intracellular mrna localization GO:0008298 4 0.016
axon target recognition GO:0007412 4 0.016
regulation of protein localization to nucleus GO:1900180 60 0.015
lamellipodium organization GO:0097581 29 0.015
stem cell fate determination GO:0048867 2 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
negative regulation of cell development GO:0010721 169 0.015
divalent inorganic cation transport GO:0072511 178 0.015
skeletal muscle organ development GO:0060538 163 0.015
negative regulation of cell projection organization GO:0031345 56 0.015
telencephalon development GO:0021537 186 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
protein deacylation GO:0035601 36 0.015
positive regulation of cell death GO:0010942 224 0.015
regulation of mrna processing GO:0050684 41 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
negative regulation of epithelial cell proliferation GO:0050680 64 0.015
macromolecule methylation GO:0043414 120 0.015
trophectodermal cell differentiation GO:0001829 21 0.015
actin filament based movement GO:0030048 23 0.015
monosaccharide metabolic process GO:0005996 106 0.015
regulation of cell cycle phase transition GO:1901987 77 0.015
response to oxygen levels GO:0070482 62 0.015
regulation of engulfment of apoptotic cell GO:1901074 2 0.015
skin development GO:0043588 220 0.015
negative regulation of dna replication GO:0008156 4 0.015
protein localization to nucleus GO:0034504 121 0.015
negative regulation of growth GO:0045926 99 0.015
regulation of membrane potential GO:0042391 192 0.015
protein localization to plasma membrane GO:0072659 57 0.015
neuron apoptotic process GO:0051402 142 0.015
chondrocyte hypertrophy GO:0003415 4 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
response to inorganic substance GO:0010035 96 0.015
multicellular organismal signaling GO:0035637 91 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
regulation of leukocyte mediated immunity GO:0002703 104 0.014
positive regulation of neuron projection development GO:0010976 79 0.014
histone h4 k16 acetylation GO:0043984 3 0.014
protein processing GO:0016485 163 0.014
autophagy GO:0006914 45 0.014
regulation of protein processing GO:0070613 96 0.014
transmembrane transport GO:0055085 412 0.014
response to amino acid GO:0043200 37 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
response to organic cyclic compound GO:0014070 198 0.014
actin filament organization GO:0007015 113 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
regulation of chromatin organization GO:1902275 57 0.014
anatomical structure homeostasis GO:0060249 145 0.014
regulation of inflammatory response GO:0050727 147 0.014
protein import GO:0017038 101 0.014
negative regulation of response to dna damage stimulus GO:2001021 10 0.014
glial cell differentiation GO:0010001 131 0.014
bmp signaling pathway GO:0030509 93 0.014
regulation of cell division GO:0051302 76 0.014
rna localization GO:0006403 23 0.014
protein deacetylation GO:0006476 32 0.014
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.014
blastocyst formation GO:0001825 33 0.014
interleukin 10 secretion GO:0072608 4 0.014
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
chromatin silencing at rdna GO:0000183 3 0.014
regulation of mitotic sister chromatid segregation GO:0033047 12 0.014
positive regulation of protein catabolic process GO:0045732 60 0.014
regulation of cell migration GO:0030334 219 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
interleukin 5 secretion GO:0072603 2 0.014
regulation of stem cell differentiation GO:2000736 50 0.014
microtubule polymerization GO:0046785 12 0.014
positive regulation of kinase activity GO:0033674 155 0.014
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.014
positive regulation of intracellular transport GO:0032388 70 0.013
regulation of histone modification GO:0031056 56 0.013
response to growth factor GO:0070848 198 0.013
transmission of nerve impulse GO:0019226 76 0.013
epidermis development GO:0008544 187 0.013
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.013
positive regulation of cell division GO:0051781 31 0.013
cell adhesion GO:0007155 329 0.013
mesendoderm development GO:0048382 3 0.013
circulatory system process GO:0003013 197 0.013
regulation of meiotic cell cycle GO:0051445 34 0.013
cellular response to acid chemical GO:0071229 68 0.013
regulation of secretion GO:0051046 274 0.013
mrna 3 end processing GO:0031124 16 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.013
hexose metabolic process GO:0019318 98 0.013
lymphocyte differentiation GO:0030098 242 0.013
nitrogen compound transport GO:0071705 271 0.013
negative regulation of cytoskeleton organization GO:0051494 36 0.013
cellular response to amino acid stimulus GO:0071230 29 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
inositol phosphate mediated signaling GO:0048016 13 0.013
protein localization to organelle GO:0033365 185 0.013
adaptive immune response GO:0002250 155 0.013
negative regulation of protein depolymerization GO:1901880 21 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013

Dyrk1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013