Mus musculus

242 known processes

Edn1

endothelin 1

(Aliases: ET-1,preproET)

Edn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle system process GO:0003012 141 0.868
muscle contraction GO:0006936 101 0.742
purine ribonucleotide metabolic process GO:0009150 290 0.550
regulation of anatomical structure size GO:0090066 178 0.518
Human
actin cytoskeleton organization GO:0030036 220 0.488
Human
purine nucleotide metabolic process GO:0006163 302 0.472
nucleoside phosphate metabolic process GO:0006753 338 0.399
nucleobase containing small molecule metabolic process GO:0055086 352 0.391
response to decreased oxygen levels GO:0036293 59 0.364
blood circulation GO:0008015 195 0.356
inflammatory response GO:0006954 244 0.356
purine containing compound metabolic process GO:0072521 311 0.352
circulatory system process GO:0003013 197 0.338
cation transport GO:0006812 399 0.333
Mouse
response to organonitrogen compound GO:0010243 246 0.310
smooth muscle contraction GO:0006939 44 0.308
nucleoside phosphate biosynthetic process GO:1901293 79 0.306
regulation of blood circulation GO:1903522 93 0.300
Human
cell growth GO:0016049 130 0.299
forebrain development GO:0030900 302 0.299
ribonucleotide metabolic process GO:0009259 291 0.291
developmental cell growth GO:0048588 84 0.285
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.283
regulation of nucleotide metabolic process GO:0006140 169 0.282
regulation of organelle organization GO:0033043 289 0.274
Human
ribose phosphate biosynthetic process GO:0046390 59 0.272
negative regulation of nucleotide metabolic process GO:0045980 16 0.268
ribose phosphate metabolic process GO:0019693 291 0.265
camp metabolic process GO:0046058 40 0.262
regulation of nucleotide biosynthetic process GO:0030808 34 0.257
regulation of ion transmembrane transport GO:0034765 119 0.248
Mouse
nucleotide metabolic process GO:0009117 332 0.247
ribonucleotide biosynthetic process GO:0009260 59 0.247
g protein coupled receptor signaling pathway GO:0007186 243 0.241
carbohydrate derivative biosynthetic process GO:1901137 183 0.238
cellular amine metabolic process GO:0044106 44 0.238
epithelial tube morphogenesis GO:0060562 303 0.235
positive regulation of cell development GO:0010720 237 0.234
Human
purine nucleotide biosynthetic process GO:0006164 65 0.231
organonitrogen compound biosynthetic process GO:1901566 192 0.225
response to organic cyclic compound GO:0014070 198 0.225
vascular process in circulatory system GO:0003018 62 0.220
Human
purine ribonucleotide biosynthetic process GO:0009152 59 0.219
calcium ion transport GO:0006816 159 0.219
calcium ion homeostasis GO:0055074 127 0.214
neuron projection extension GO:1990138 64 0.210
rho protein signal transduction GO:0007266 32 0.208
regulation of neuron differentiation GO:0045664 281 0.206
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.203
organophosphate biosynthetic process GO:0090407 122 0.203
cyclic purine nucleotide metabolic process GO:0052652 43 0.199
apoptotic signaling pathway GO:0097190 306 0.197
regulation of system process GO:0044057 200 0.196
developmental maturation GO:0021700 193 0.195
regulation of metal ion transport GO:0010959 106 0.194
Mouse
blood vessel morphogenesis GO:0048514 285 0.192
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.191
negative regulation of phosphate metabolic process GO:0045936 184 0.191
amine metabolic process GO:0009308 45 0.190
developmental growth involved in morphogenesis GO:0060560 138 0.186
regulation of cell motility GO:2000145 236 0.182
Human Mouse
negative regulation of purine nucleotide biosynthetic process GO:1900372 6 0.177
response to oxidative stress GO:0006979 123 0.177
regulation of blood vessel size GO:0050880 56 0.173
Human
renal sodium excretion GO:0035812 3 0.173
small gtpase mediated signal transduction GO:0007264 97 0.173
muscle cell differentiation GO:0042692 261 0.168
Human
angiogenesis GO:0001525 201 0.167
divalent inorganic cation homeostasis GO:0072507 138 0.166
axonogenesis GO:0007409 274 0.166
ion transmembrane transport GO:0034220 361 0.163
Mouse
nucleotide biosynthetic process GO:0009165 78 0.162
regulation of cellular amine metabolic process GO:0033238 20 0.161
ameboidal type cell migration GO:0001667 128 0.160
Mouse
cell junction organization GO:0034330 77 0.153
dopamine metabolic process GO:0042417 23 0.153
cellular amino acid metabolic process GO:0006520 103 0.153
ras protein signal transduction GO:0007265 77 0.151
regulation of cell cycle GO:0051726 281 0.147
Human
mapk cascade GO:0000165 281 0.146
Human
cellular metal ion homeostasis GO:0006875 151 0.146
telencephalon development GO:0021537 186 0.145
regulation of protein kinase activity GO:0045859 232 0.144
Human
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.144
positive regulation of renal sodium excretion GO:0035815 2 0.143
cell chemotaxis GO:0060326 81 0.140
sensory perception of pain GO:0019233 47 0.140
regulation of cell growth GO:0001558 91 0.138
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.138
sensory perception GO:0007600 245 0.137
organic cyclic compound catabolic process GO:1901361 295 0.137
transmembrane transport GO:0055085 412 0.137
Mouse
divalent metal ion transport GO:0070838 172 0.136
cell adhesion GO:0007155 329 0.135
renal system process GO:0003014 48 0.132
cellular response to oxidative stress GO:0034599 76 0.130
camp biosynthetic process GO:0006171 31 0.129
positive regulation of cellular amine metabolic process GO:0033240 5 0.129
cellular calcium ion homeostasis GO:0006874 119 0.129
regulation of renal sodium excretion GO:0035813 3 0.127
positive regulation of cell migration GO:0030335 109 0.126
Human
single organism cell adhesion GO:0098602 156 0.126
heart process GO:0003015 94 0.125
Human
erk1 and erk2 cascade GO:0070371 77 0.124
positive regulation of protein phosphorylation GO:0001934 242 0.122
Human
trunk neural crest cell migration GO:0036484 4 0.122
stem cell differentiation GO:0048863 268 0.121
regulation of camp biosynthetic process GO:0030817 25 0.120
purine ribonucleoside metabolic process GO:0046128 241 0.119
negative regulation of neuron differentiation GO:0045665 101 0.119
positive regulation of mapk cascade GO:0043410 170 0.118
Human
regulation of mapk cascade GO:0043408 248 0.117
Human
positive regulation of cell growth GO:0030307 33 0.116
regulation of purine nucleotide metabolic process GO:1900542 169 0.115
cell maturation GO:0048469 127 0.113
locomotory behavior GO:0007626 195 0.113
second messenger mediated signaling GO:0019932 73 0.113
Human
cation homeostasis GO:0055080 212 0.112
regulation of secretion GO:0051046 274 0.109
single organismal cell cell adhesion GO:0016337 131 0.106
cellular divalent inorganic cation homeostasis GO:0072503 127 0.106
molting cycle GO:0042303 90 0.105
regulation of ion homeostasis GO:2000021 64 0.103
mesenchymal cell differentiation GO:0048762 107 0.101
multicellular organismal homeostasis GO:0048871 164 0.100
Mouse
leukocyte migration GO:0050900 124 0.099
gland development GO:0048732 330 0.099
response to hypoxia GO:0001666 58 0.099
negative regulation of phosphorus metabolic process GO:0010563 184 0.098
cellular ion homeostasis GO:0006873 165 0.097
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.096
striated muscle tissue development GO:0014706 293 0.095
regulation of membrane potential GO:0042391 192 0.095
nucleoside metabolic process GO:0009116 246 0.095
enteric smooth muscle cell differentiation GO:0035645 1 0.094
nitrogen compound transport GO:0071705 271 0.093
Human
morphogenesis of a branching epithelium GO:0061138 193 0.093
vasodilation GO:0042311 28 0.092
negative regulation of cell motility GO:2000146 61 0.091
urogenital system development GO:0001655 261 0.089
regulation of neuron projection development GO:0010975 169 0.089
skeletal system development GO:0001501 356 0.088
regulation of actin filament based process GO:0032970 99 0.086
Human
negative regulation of nervous system development GO:0051961 156 0.086
metal ion homeostasis GO:0055065 189 0.085
purine containing compound biosynthetic process GO:0072522 70 0.085
divalent inorganic cation transport GO:0072511 178 0.085
organophosphate catabolic process GO:0046434 232 0.084
regulation of dopamine metabolic process GO:0042053 10 0.084
regulation of body fluid levels GO:0050878 162 0.084
neuron projection guidance GO:0097485 141 0.084
response to radiation GO:0009314 165 0.084
positive regulation of protein modification process GO:0031401 299 0.084
Human
actin filament organization GO:0007015 113 0.082
sympathetic neuron projection guidance GO:0097491 4 0.082
negative regulation of neuron projection development GO:0010977 50 0.081
regulation of apoptotic signaling pathway GO:2001233 197 0.080
nucleoside phosphate catabolic process GO:1901292 222 0.080
negative regulation of cellular component organization GO:0051129 194 0.079
regulation of calcium ion transport GO:0051924 69 0.079
skin development GO:0043588 220 0.079
regulation of transferase activity GO:0051338 263 0.079
Human
regulation of actin cytoskeleton organization GO:0032956 84 0.079
Human
heterocycle catabolic process GO:0046700 280 0.078
wound healing GO:0042060 157 0.078
cellular homeostasis GO:0019725 240 0.077
negative regulation of cell development GO:0010721 169 0.077
regulation of axon extension GO:0030516 43 0.076
chemotaxis GO:0006935 247 0.076
glial cell differentiation GO:0010001 131 0.075
sympathetic neuron projection extension GO:0097490 4 0.075
regulation of response to wounding GO:1903034 189 0.075
positive regulation of growth GO:0045927 104 0.075
regulation of inflammatory response GO:0050727 147 0.074
positive regulation of ion transport GO:0043270 65 0.074
Mouse
response to pain GO:0048265 26 0.074
neural crest cell development GO:0014032 48 0.073
epidermis development GO:0008544 187 0.073
regulation of cellular ketone metabolic process GO:0010565 66 0.072
negative regulation of response to oxidative stress GO:1902883 10 0.072
positive regulation of cytokine production GO:0001819 174 0.071
regulation of cytoskeleton organization GO:0051493 122 0.071
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.069
regulation of response to oxidative stress GO:1902882 19 0.068
regulation of cell activation GO:0050865 289 0.068
epithelial cell proliferation GO:0050673 174 0.068
penile erection GO:0043084 2 0.068
temperature homeostasis GO:0001659 26 0.068
Mouse
glycosyl compound catabolic process GO:1901658 206 0.067
regulation of defense response GO:0031347 233 0.067
cardiac muscle cell contraction GO:0086003 7 0.066
regulation of heart contraction GO:0008016 77 0.066
Human
cellular response to lipid GO:0071396 145 0.066
regulation of neural precursor cell proliferation GO:2000177 70 0.065
skeletal muscle organ development GO:0060538 163 0.065
ventral trunk neural crest cell migration GO:0036486 4 0.064
purine ribonucleotide catabolic process GO:0009154 208 0.064
nucleotide catabolic process GO:0009166 217 0.063
organonitrogen compound catabolic process GO:1901565 264 0.063
positive regulation of secretion by cell GO:1903532 114 0.062
Human
spermatogenesis GO:0007283 284 0.062
negative regulation of cell activation GO:0050866 111 0.062
adult behavior GO:0030534 135 0.061
myeloid leukocyte migration GO:0097529 57 0.061
negative regulation of oxidative stress induced cell death GO:1903202 9 0.061
negative regulation of camp metabolic process GO:0030815 5 0.061
negative regulation of cellular response to oxidative stress GO:1900408 10 0.061
lung alveolus development GO:0048286 45 0.061
Mouse
vasoconstriction GO:0042310 27 0.061
Human
response to light stimulus GO:0009416 135 0.060
axon guidance GO:0007411 141 0.060
midgut development GO:0007494 4 0.060
regulation of cytokine production GO:0001817 266 0.060
heart contraction GO:0060047 93 0.059
Human
positive regulation of reproductive process GO:2000243 19 0.059
hair cycle GO:0042633 90 0.059
ossification GO:0001503 216 0.059
regulation of protein localization GO:0032880 231 0.058
regulation of blood pressure GO:0008217 93 0.058
peptide secretion GO:0002790 114 0.058
Human
fat cell differentiation GO:0045444 160 0.058
extrinsic apoptotic signaling pathway GO:0097191 126 0.058
positive regulation of secretion GO:0051047 130 0.058
mesenchymal cell development GO:0014031 93 0.057
negative regulation of immune system process GO:0002683 209 0.057
response to extracellular stimulus GO:0009991 127 0.057
excretion GO:0007588 22 0.057
purine nucleoside catabolic process GO:0006152 205 0.057
epithelial cell development GO:0002064 159 0.057
skeletal system morphogenesis GO:0048705 203 0.057
aromatic compound catabolic process GO:0019439 286 0.056
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.055
myeloid cell differentiation GO:0030099 233 0.055
cyclic nucleotide metabolic process GO:0009187 59 0.055
positive regulation of urine volume GO:0035810 6 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
carbohydrate derivative catabolic process GO:1901136 231 0.055
nucleoside triphosphate catabolic process GO:0009143 205 0.055
intrinsic apoptotic signaling pathway GO:0097193 132 0.055
purine containing compound catabolic process GO:0072523 213 0.055
male gamete generation GO:0048232 285 0.054
immune effector process GO:0002252 321 0.053
hair follicle development GO:0001942 85 0.053
negative regulation of endothelial cell migration GO:0010596 4 0.052
regulation of cellular response to oxidative stress GO:1900407 19 0.052
leukocyte differentiation GO:0002521 342 0.052
mesenchyme development GO:0060485 152 0.051
response to growth factor GO:0070848 198 0.051
cellular ketone metabolic process GO:0042180 84 0.051
regulation of cell size GO:0008361 72 0.051
Human
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.050
response to lipopolysaccharide GO:0032496 128 0.050
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.050
positive regulation of neuron projection development GO:0010976 79 0.049
negative regulation of camp biosynthetic process GO:0030818 5 0.049
catecholamine metabolic process GO:0006584 30 0.049
cardiac muscle tissue development GO:0048738 130 0.049
response to inorganic substance GO:0010035 96 0.049
regulation of excretion GO:0044062 5 0.049
regulation of ph GO:0006885 26 0.049
regulation of extent of cell growth GO:0061387 52 0.048
regulation of chemotaxis GO:0050920 53 0.048
leukocyte chemotaxis GO:0030595 69 0.048
purine nucleoside metabolic process GO:0042278 241 0.047
pallium development GO:0021543 120 0.047
response to peptide GO:1901652 136 0.047
anatomical structure homeostasis GO:0060249 145 0.047
oxidation reduction process GO:0055114 342 0.047
Human Mouse
regulation of ion transport GO:0043269 215 0.047
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.047
regulation of muscle system process GO:0090257 80 0.047
purine ribonucleoside catabolic process GO:0046130 205 0.047
ribonucleotide catabolic process GO:0009261 208 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.046
negative regulation of protein metabolic process GO:0051248 282 0.046
Human
regulation of tube size GO:0035150 57 0.046
Human
maintenance of location GO:0051235 89 0.046
response to drug GO:0042493 75 0.046
response to molecule of bacterial origin GO:0002237 143 0.046
regulation of hydrolase activity GO:0051336 246 0.046
cell type specific apoptotic process GO:0097285 268 0.045
camera type eye development GO:0043010 266 0.045
peptidyl tyrosine phosphorylation GO:0018108 143 0.045
positive regulation of epithelial cell proliferation GO:0050679 68 0.044
neuronal action potential GO:0019228 54 0.044
negative regulation of cell projection organization GO:0031345 56 0.044
ribonucleoside metabolic process GO:0009119 245 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
glycosyl compound metabolic process GO:1901657 246 0.044
regulation of cell migration GO:0030334 219 0.044
Human Mouse
response to nutrient levels GO:0031667 109 0.044
cell junction assembly GO:0034329 52 0.043
response to peptide hormone GO:0043434 127 0.043
locomotion involved in locomotory behavior GO:0031987 8 0.043
mating GO:0007618 27 0.043
nucleoside catabolic process GO:0009164 206 0.043
carbohydrate transport GO:0008643 62 0.042
tissue migration GO:0090130 68 0.042
digestive tract development GO:0048565 190 0.042
protein secretion GO:0009306 111 0.042
ribonucleoside triphosphate catabolic process GO:0009203 199 0.042
positive regulation of cellular catabolic process GO:0031331 148 0.042
regulation of angiogenesis GO:0045765 81 0.042
posttranscriptional regulation of gene expression GO:0010608 155 0.042
positive regulation of cell death GO:0010942 224 0.042
organ growth GO:0035265 117 0.041
regulation of catecholamine metabolic process GO:0042069 10 0.041
branching morphogenesis of an epithelial tube GO:0048754 159 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
Human
cardiac chamber development GO:0003205 108 0.041
regulation of kinase activity GO:0043549 249 0.041
Human
regulation of cell adhesion GO:0030155 154 0.040
ribonucleoside catabolic process GO:0042454 206 0.040
organic hydroxy compound metabolic process GO:1901615 203 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
positive regulation of axon extension GO:0045773 20 0.039
regulation of homeostatic process GO:0032844 182 0.039
neutrophil chemotaxis GO:0030593 36 0.039
neural crest cell migration GO:0001755 32 0.039
Mouse
muscle hypertrophy GO:0014896 24 0.039
Human
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.039
calcium ion transmembrane transport GO:0070588 85 0.039
purine nucleotide catabolic process GO:0006195 211 0.039
tissue remodeling GO:0048771 102 0.039
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.039
negative regulation of cell migration GO:0030336 59 0.038
response to oxygen levels GO:0070482 62 0.038
forebrain cell migration GO:0021885 58 0.038
cellular response to biotic stimulus GO:0071216 92 0.038
gtp catabolic process GO:0006184 143 0.038
morphogenesis of a branching structure GO:0001763 203 0.038
neutrophil migration GO:1990266 37 0.037
neural precursor cell proliferation GO:0061351 121 0.037
actin mediated cell contraction GO:0070252 15 0.037
cytosolic calcium ion homeostasis GO:0051480 70 0.037
regulation of erk1 and erk2 cascade GO:0070372 71 0.036
regulation of nucleotide catabolic process GO:0030811 122 0.036
actin filament based movement GO:0030048 23 0.036
positive regulation of nervous system development GO:0051962 221 0.036
hindbrain development GO:0030902 128 0.036
phenol containing compound metabolic process GO:0018958 60 0.036
positive regulation of catecholamine metabolic process GO:0045915 2 0.035
regulation of protein serine threonine kinase activity GO:0071900 157 0.035
Human
regulation of cell projection organization GO:0031344 206 0.035
generation of precursor metabolites and energy GO:0006091 103 0.035
cell matrix adhesion GO:0007160 68 0.035
negative regulation of growth GO:0045926 99 0.035
protein maturation GO:0051604 176 0.034
phenol containing compound biosynthetic process GO:0046189 21 0.034
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.034
transmission of nerve impulse GO:0019226 76 0.034
reactive oxygen species metabolic process GO:0072593 84 0.034
negative regulation of apoptotic signaling pathway GO:2001234 104 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.034
cation transmembrane transport GO:0098655 266 0.034
Mouse
mammary gland lobule development GO:0061377 22 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.034
facial nerve structural organization GO:0021612 10 0.034
multicellular organism growth GO:0035264 161 0.033
organelle localization GO:0051640 179 0.033
digestive system development GO:0055123 200 0.033
cell death in response to oxidative stress GO:0036473 24 0.033
regulation of establishment of protein localization GO:0070201 181 0.033
sequestering of calcium ion GO:0051208 18 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
autonomic nervous system development GO:0048483 43 0.033
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
cell cell junction organization GO:0045216 72 0.033
posterior midgut development GO:0007497 1 0.032
positive regulation of neuron differentiation GO:0045666 141 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
positive regulation of chemotaxis GO:0050921 38 0.032
rhythmic process GO:0048511 174 0.032
regulation of cellular component size GO:0032535 121 0.032
Human
cytokine mediated signaling pathway GO:0019221 115 0.032
peptidyl tyrosine modification GO:0018212 145 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.031
inorganic ion transmembrane transport GO:0098660 234 0.031
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.031
Human
regulation of transmembrane transport GO:0034762 128 0.031
Mouse
response to hydrogen peroxide GO:0042542 32 0.031
granulocyte chemotaxis GO:0071621 39 0.031
negative regulation of molecular function GO:0044092 258 0.031
t cell activation GO:0042110 289 0.031
peptidyl amino acid modification GO:0018193 336 0.031
positive regulation of organelle organization GO:0010638 128 0.031
Human
phagocytosis GO:0006909 66 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
membrane organization GO:0061024 245 0.031
positive regulation of nucleotide metabolic process GO:0045981 114 0.031
glomerular mesangial cell proliferation GO:0072110 3 0.030
myotube differentiation GO:0014902 105 0.030
endocrine system development GO:0035270 98 0.030
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.030
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 5 0.030
cyclic nucleotide biosynthetic process GO:0009190 44 0.030
response to amino acid GO:0043200 37 0.030
myeloid leukocyte differentiation GO:0002573 119 0.030
development of primary sexual characteristics GO:0045137 143 0.030
regulation of camp metabolic process GO:0030814 30 0.030
positive regulation of cell projection organization GO:0031346 95 0.029
muscle adaptation GO:0043500 39 0.029
Human
smoothened signaling pathway GO:0007224 105 0.029
granulocyte migration GO:0097530 43 0.029
respiratory tube development GO:0030323 167 0.029
Mouse
adaptive immune response GO:0002250 155 0.029
heart morphogenesis GO:0003007 178 0.029
morphogenesis of an epithelial sheet GO:0002011 27 0.029
cytoplasmic transport GO:0016482 234 0.029
positive regulation of smooth muscle cell migration GO:0014911 4 0.029
cardiac muscle hypertrophy GO:0003300 23 0.029
Human
actin filament bundle assembly GO:0051017 40 0.029
venous blood vessel development GO:0060841 13 0.029
renal system development GO:0072001 225 0.028
regulation of epithelial cell proliferation GO:0050678 141 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
negative regulation of inflammatory response GO:0050728 61 0.028
striated muscle contraction GO:0006941 45 0.028
guanosine containing compound metabolic process GO:1901068 144 0.028
regulation of cellular response to stress GO:0080135 159 0.028
Human
negative regulation of hydrolase activity GO:0051346 71 0.028
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.028
osteoclast differentiation GO:0030316 62 0.028
negative regulation of axon extension GO:0030517 19 0.028
negative regulation of protein phosphorylation GO:0001933 126 0.028
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.027
tissue homeostasis GO:0001894 115 0.027
cardiac muscle contraction GO:0060048 32 0.027
cellular protein complex assembly GO:0043623 116 0.027
positive regulation of cell adhesion GO:0045785 80 0.027
lymphocyte proliferation GO:0046651 164 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
cellular lipid metabolic process GO:0044255 323 0.027
Human Mouse
organic hydroxy compound biosynthetic process GO:1901617 77 0.027
myeloid cell homeostasis GO:0002262 114 0.027
dendrite development GO:0016358 115 0.027
respiratory system development GO:0060541 190 0.026
Mouse
sphingolipid metabolic process GO:0006665 45 0.026
amide transport GO:0042886 138 0.026
Human
cartilage development GO:0051216 140 0.026
peptide transport GO:0015833 133 0.026
Human
asymmetric stem cell division GO:0098722 3 0.026
response to steroid hormone GO:0048545 56 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
negative regulation of cell growth GO:0030308 44 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
engulfment of apoptotic cell GO:0043652 3 0.026
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.026
regulation of fat cell differentiation GO:0045598 81 0.026
regulation of striated muscle cell differentiation GO:0051153 81 0.026
Human
regulation of lymphocyte activation GO:0051249 240 0.025
regulation of endopeptidase activity GO:0052548 89 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
negative regulation of kinase activity GO:0033673 81 0.025
regulation of cell substrate adhesion GO:0010810 73 0.025
copulation GO:0007620 7 0.025
macromolecule catabolic process GO:0009057 281 0.025
regulation of leukocyte differentiation GO:1902105 159 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
protein processing GO:0016485 163 0.025
sensory perception of mechanical stimulus GO:0050954 107 0.025
energy derivation by oxidation of organic compounds GO:0015980 77 0.025
homeostasis of number of cells GO:0048872 210 0.025
heat generation GO:0031649 13 0.025
myeloid leukocyte activation GO:0002274 83 0.025
gliogenesis GO:0042063 141 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
regulation of t cell activation GO:0050863 170 0.024
regulation of response to reactive oxygen species GO:1901031 9 0.024
detection of chemical stimulus involved in sensory perception of pain GO:0050968 3 0.024
cellular carbohydrate metabolic process GO:0044262 119 0.024
protein catabolic process GO:0030163 221 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
meiotic nuclear division GO:0007126 115 0.024
sequestering of metal ion GO:0051238 19 0.024
negative regulation of protein modification process GO:0031400 163 0.024
positive regulation of calcium ion transport GO:0051928 27 0.024
exocrine system development GO:0035272 45 0.024
substrate dependent cell migration GO:0006929 18 0.023
regulation of urine volume GO:0035809 6 0.023
epithelial cell migration GO:0010631 63 0.023
glucose transport GO:0015758 56 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.023
response to insulin GO:0032868 100 0.023
carbohydrate metabolic process GO:0005975 230 0.023
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.023
positive regulation of cellular component biogenesis GO:0044089 94 0.023
Human
extracellular matrix organization GO:0030198 147 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.023
lipid biosynthetic process GO:0008610 179 0.023
Human Mouse

Edn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.140
disease of anatomical entity DOID:7 0 0.140
nervous system disease DOID:863 0 0.140
neuropathy DOID:870 0 0.140
charcot marie tooth disease DOID:10595 0 0.088
gastrointestinal system disease DOID:77 0 0.050
musculoskeletal system disease DOID:17 0 0.028