Mus musculus

258 known processes

Eif2ak3

eukaryotic translation initiation factor 2 alpha kinase 3

(Aliases: Perk,Pek,AI427929)

Eif2ak3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.258
regulation of cellular amine metabolic process GO:0033238 20 0.243
multicellular organism growth GO:0035264 161 0.222
cellular amine metabolic process GO:0044106 44 0.220
transepithelial chloride transport GO:0030321 4 0.195
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.182
regulation of ion transport GO:0043269 215 0.175
response to organonitrogen compound GO:0010243 246 0.159
regulation of organelle organization GO:0033043 289 0.152
peptidyl amino acid modification GO:0018193 336 0.150
Worm
cellular amino acid metabolic process GO:0006520 103 0.150
regulation of apoptotic signaling pathway GO:2001233 197 0.147
immune effector process GO:0002252 321 0.140
homeostasis of number of cells GO:0048872 210 0.139
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.138
ion transmembrane transport GO:0034220 361 0.135
extracellular matrix organization GO:0030198 147 0.132
cation transport GO:0006812 399 0.124
ribose phosphate metabolic process GO:0019693 291 0.123
chemotaxis GO:0006935 247 0.120
gland development GO:0048732 330 0.120
t cell activation GO:0042110 289 0.118
response to endoplasmic reticulum stress GO:0034976 53 0.117
synaptic transmission GO:0007268 329 0.115
regulation of membrane potential GO:0042391 192 0.110
leukocyte differentiation GO:0002521 342 0.107
nucleoside phosphate metabolic process GO:0006753 338 0.106
myeloid leukocyte differentiation GO:0002573 119 0.105
apoptotic signaling pathway GO:0097190 306 0.105
amine metabolic process GO:0009308 45 0.100
spermatogenesis GO:0007283 284 0.100
cytokine production GO:0001816 319 0.099
cellular chemical homeostasis GO:0055082 215 0.099
purine containing compound metabolic process GO:0072521 311 0.096
cellular response to lipid GO:0071396 145 0.092
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.091
regulation of cellular amino acid metabolic process GO:0006521 5 0.091
response to light stimulus GO:0009416 135 0.090
response to radiation GO:0009314 165 0.090
purine ribonucleotide metabolic process GO:0009150 290 0.087
respiratory tube development GO:0030323 167 0.085
macromolecule catabolic process GO:0009057 281 0.085
cellular metal ion homeostasis GO:0006875 151 0.084
cytoplasmic transport GO:0016482 234 0.083
cellular divalent inorganic cation homeostasis GO:0072503 127 0.083
lipid biosynthetic process GO:0008610 179 0.083
regulation of cellular response to stress GO:0080135 159 0.083
regulation of cellular ketone metabolic process GO:0010565 66 0.082
regulation of homeostatic process GO:0032844 182 0.080
regulation of transmembrane transport GO:0034762 128 0.080
negative regulation of intracellular signal transduction GO:1902532 167 0.079
cation homeostasis GO:0055080 212 0.078
respiratory system development GO:0060541 190 0.077
second messenger mediated signaling GO:0019932 73 0.076
g protein coupled receptor signaling pathway GO:0007186 243 0.074
negative regulation of cellular amine metabolic process GO:0033239 1 0.074
multicellular organismal homeostasis GO:0048871 164 0.074
epithelial tube morphogenesis GO:0060562 303 0.074
regulation of neuron differentiation GO:0045664 281 0.074
lung development GO:0030324 164 0.074
anion transport GO:0006820 177 0.073
ribonucleotide metabolic process GO:0009259 291 0.073
protein modification by small protein conjugation GO:0032446 187 0.072
placenta development GO:0001890 140 0.072
nitrogen compound transport GO:0071705 271 0.071
positive regulation of cell development GO:0010720 237 0.070
regulation of secretion GO:0051046 274 0.070
circulatory system process GO:0003013 197 0.070
divalent inorganic cation transport GO:0072511 178 0.069
regulation of protein transport GO:0051223 163 0.069
sequestering of calcium ion GO:0051208 18 0.069
organonitrogen compound biosynthetic process GO:1901566 192 0.069
nucleoside triphosphate metabolic process GO:0009141 230 0.069
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.068
cellular ion homeostasis GO:0006873 165 0.068
organic anion transport GO:0015711 137 0.067
cellular ketone metabolic process GO:0042180 84 0.067
positive regulation of protein modification process GO:0031401 299 0.067
divalent metal ion transport GO:0070838 172 0.067
regulation of cellular catabolic process GO:0031329 242 0.067
Fly
mapk cascade GO:0000165 281 0.066
carbohydrate derivative catabolic process GO:1901136 231 0.066
negative regulation of phosphate metabolic process GO:0045936 184 0.066
inflammatory response GO:0006954 244 0.066
protein modification by small protein conjugation or removal GO:0070647 207 0.066
dna metabolic process GO:0006259 303 0.066
regulation of system process GO:0044057 200 0.065
regulation of protein kinase activity GO:0045859 232 0.064
camera type eye development GO:0043010 266 0.064
sequestering of metal ion GO:0051238 19 0.063
calcium ion transport GO:0006816 159 0.063
ribonucleoside metabolic process GO:0009119 245 0.063
endomembrane system organization GO:0010256 147 0.063
anatomical structure homeostasis GO:0060249 145 0.062
regulation of cytokine production GO:0001817 266 0.062
cellular homeostasis GO:0019725 240 0.062
epithelial cell proliferation GO:0050673 174 0.062
positive regulation of cellular amine metabolic process GO:0033240 5 0.061
negative regulation of cell proliferation GO:0008285 296 0.061
spermatid development GO:0007286 108 0.061
carboxylic acid transport GO:0046942 100 0.061
ribonucleoside catabolic process GO:0042454 206 0.061
regulation of reactive oxygen species metabolic process GO:2000377 40 0.061
protein processing GO:0016485 163 0.060
regulation of kinase activity GO:0043549 249 0.060
small gtpase mediated signal transduction GO:0007264 97 0.060
response to growth factor GO:0070848 198 0.060
mitochondrion organization GO:0007005 134 0.059
leukocyte proliferation GO:0070661 172 0.059
regulation of secretion by cell GO:1903530 249 0.059
regulation of defense response GO:0031347 233 0.059
purine nucleotide metabolic process GO:0006163 302 0.058
male gamete generation GO:0048232 285 0.058
alcohol metabolic process GO:0006066 116 0.058
cell activation involved in immune response GO:0002263 126 0.057
protein ubiquitination GO:0016567 171 0.057
engulfment of apoptotic cell GO:0043652 3 0.057
actin cytoskeleton organization GO:0030036 220 0.056
regulation of cell cycle GO:0051726 281 0.056
Fly
gliogenesis GO:0042063 141 0.056
reactive oxygen species metabolic process GO:0072593 84 0.056
regulation of chemotaxis GO:0050920 53 0.055
response to inorganic substance GO:0010035 96 0.055
regulation of ion transmembrane transporter activity GO:0032412 54 0.055
defense response to bacterium GO:0042742 119 0.055
lipid transport GO:0006869 98 0.054
nucleoside metabolic process GO:0009116 246 0.054
developmental maturation GO:0021700 193 0.054
maintenance of location GO:0051235 89 0.053
regulation of cell projection organization GO:0031344 206 0.053
photoreceptor cell morphogenesis GO:0008594 3 0.053
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
regulation of leukocyte differentiation GO:1902105 159 0.053
metal ion homeostasis GO:0055065 189 0.052
negative regulation of protein metabolic process GO:0051248 282 0.052
organic hydroxy compound transport GO:0015850 93 0.052
glycosyl compound catabolic process GO:1901658 206 0.051
cellular response to growth factor stimulus GO:0071363 197 0.051
regulation of map kinase activity GO:0043405 120 0.051
exocytosis GO:0006887 121 0.050
nucleotide metabolic process GO:0009117 332 0.050
positive regulation of secretion GO:0051047 130 0.050
ras protein signal transduction GO:0007265 77 0.050
regulation of transferase activity GO:0051338 263 0.050
cell type specific apoptotic process GO:0097285 268 0.049
regulation of transporter activity GO:0032409 57 0.049
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.049
regulation of ion transmembrane transport GO:0034765 119 0.049
organelle assembly GO:0070925 177 0.049
purine nucleoside triphosphate catabolic process GO:0009146 203 0.048
regulation of cellular component biogenesis GO:0044087 181 0.048
cellular calcium ion homeostasis GO:0006874 119 0.048
digestive system development GO:0055123 200 0.047
hematopoietic progenitor cell differentiation GO:0002244 143 0.047
tissue homeostasis GO:0001894 115 0.047
regulation of hydrolase activity GO:0051336 246 0.046
organophosphate biosynthetic process GO:0090407 122 0.046
purine nucleotide catabolic process GO:0006195 211 0.046
positive regulation of secretion by cell GO:1903532 114 0.046
positive regulation of homeostatic process GO:0032846 64 0.046
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.046
neuron death GO:0070997 154 0.046
response to peptide hormone GO:0043434 127 0.045
regulation of cellular component size GO:0032535 121 0.045
regulation of synaptic plasticity GO:0048167 87 0.045
sensory organ morphogenesis GO:0090596 242 0.045
leukocyte activation involved in immune response GO:0002366 126 0.045
positive regulation of cellular catabolic process GO:0031331 148 0.045
Fly
axonogenesis GO:0007409 274 0.045
regulation of t cell activation GO:0050863 170 0.044
mitochondrion distribution GO:0048311 4 0.044
protein autophosphorylation GO:0046777 61 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.044
protein localization to organelle GO:0033365 185 0.044
spermatid differentiation GO:0048515 115 0.044
muscle tissue development GO:0060537 308 0.044
regulation of mitochondrial fission GO:0090140 3 0.044
anion transmembrane transport GO:0098656 71 0.044
organonitrogen compound catabolic process GO:1901565 264 0.043
purine ribonucleotide catabolic process GO:0009154 208 0.043
purine containing compound catabolic process GO:0072523 213 0.043
canonical wnt signaling pathway GO:0060070 130 0.043
membrane organization GO:0061024 245 0.043
cellular response to external stimulus GO:0071496 88 0.043
cell adhesion GO:0007155 329 0.043
regulation of protein localization GO:0032880 231 0.042
modification dependent protein catabolic process GO:0019941 133 0.042
leukocyte homeostasis GO:0001776 79 0.042
positive regulation of cell activation GO:0050867 158 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
regulation of cell migration GO:0030334 219 0.042
appendage development GO:0048736 166 0.041
regulation of anatomical structure size GO:0090066 178 0.041
cognition GO:0050890 149 0.041
cellular lipid metabolic process GO:0044255 323 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
cellular macromolecule catabolic process GO:0044265 206 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
extracellular structure organization GO:0043062 148 0.041
modification dependent macromolecule catabolic process GO:0043632 133 0.040
associative learning GO:0008306 61 0.040
learning or memory GO:0007611 148 0.040
regulation of cell motility GO:2000145 236 0.040
lymphocyte activation involved in immune response GO:0002285 93 0.040
negative regulation of immune system process GO:0002683 209 0.040
positive regulation of cell death GO:0010942 224 0.040
nucleoside phosphate catabolic process GO:1901292 222 0.040
ribonucleotide catabolic process GO:0009261 208 0.040
lipid localization GO:0010876 126 0.039
inorganic ion transmembrane transport GO:0098660 234 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.039
negative regulation of molecular function GO:0044092 258 0.039
rho protein signal transduction GO:0007266 32 0.039
regulation of neuron apoptotic process GO:0043523 122 0.039
carbohydrate metabolic process GO:0005975 230 0.039
defense response to other organism GO:0098542 197 0.039
positive regulation of cytokine production GO:0001819 174 0.038
intrinsic apoptotic signaling pathway GO:0097193 132 0.038
digestive tract development GO:0048565 190 0.038
blood circulation GO:0008015 195 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
compound eye development GO:0048749 1 0.038
bmp signaling pathway GO:0030509 93 0.038
striated muscle tissue development GO:0014706 293 0.038
regulation of cell activation GO:0050865 289 0.038
cellular protein catabolic process GO:0044257 155 0.038
innate immune response GO:0045087 157 0.038
activation of adenylate cyclase activity GO:0007190 4 0.037
multicellular organismal signaling GO:0035637 91 0.037
peptidyl tyrosine phosphorylation GO:0018108 143 0.037
lymphocyte differentiation GO:0030098 242 0.037
nucleotide biosynthetic process GO:0009165 78 0.037
protein catabolic process GO:0030163 221 0.037
aromatic compound catabolic process GO:0019439 286 0.037
gonad development GO:0008406 141 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
regulation of blood circulation GO:1903522 93 0.037
regulation of neuron projection development GO:0010975 169 0.036
divalent inorganic cation homeostasis GO:0072507 138 0.036
embryonic placenta development GO:0001892 98 0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.036
autophagy GO:0006914 45 0.036
Fly
response to molecule of bacterial origin GO:0002237 143 0.036
response to oxidative stress GO:0006979 123 0.036
embryonic epithelial tube formation GO:0001838 130 0.036
morphogenesis of embryonic epithelium GO:0016331 159 0.036
calcium ion homeostasis GO:0055074 127 0.036
oxidation reduction process GO:0055114 342 0.036
positive regulation of protein phosphorylation GO:0001934 242 0.035
production of molecular mediator of immune response GO:0002440 103 0.035
regulation of protein serine threonine kinase activity GO:0071900 157 0.035
negative regulation of cell development GO:0010721 169 0.035
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.035
lymphocyte proliferation GO:0046651 164 0.035
regulation of neuron death GO:1901214 134 0.035
nucleoside catabolic process GO:0009164 206 0.035
nucleoside phosphate biosynthetic process GO:1901293 79 0.035
negative regulation of nervous system development GO:0051961 156 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
small molecule biosynthetic process GO:0044283 132 0.035
regulation of mapk cascade GO:0043408 248 0.035
embryonic organ morphogenesis GO:0048562 276 0.035
immune response regulating signaling pathway GO:0002764 125 0.035
leukocyte migration GO:0050900 124 0.034
positive regulation of transferase activity GO:0051347 167 0.034
neurotransmitter secretion GO:0007269 62 0.034
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.034
regulation of canonical wnt signaling pathway GO:0060828 82 0.034
reactive oxygen species biosynthetic process GO:1903409 8 0.034
transmission of nerve impulse GO:0019226 76 0.034
nucleoside triphosphate catabolic process GO:0009143 205 0.034
reactive nitrogen species metabolic process GO:2001057 0 0.034
extrinsic apoptotic signaling pathway GO:0097191 126 0.033
cellular response to organonitrogen compound GO:0071417 145 0.033
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
b cell differentiation GO:0030183 78 0.033
negative regulation of phosphorylation GO:0042326 166 0.033
cation transmembrane transport GO:0098655 266 0.033
positive regulation of lymphocyte activation GO:0051251 140 0.033
regulation of purine nucleotide metabolic process GO:1900542 169 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
regulation of cytoplasmic transport GO:1903649 112 0.032
leukocyte chemotaxis GO:0030595 69 0.032
negative regulation of protein phosphorylation GO:0001933 126 0.032
cellular response to dna damage stimulus GO:0006974 207 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
response to lipopolysaccharide GO:0032496 128 0.032
positive regulation of cell motility GO:2000147 116 0.032
gtp catabolic process GO:0006184 143 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.032
hepaticobiliary system development GO:0061008 67 0.032
positive regulation of proteolysis GO:0045862 85 0.032
positive regulation of nervous system development GO:0051962 221 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
skeletal muscle organ development GO:0060538 163 0.032
sphingolipid metabolic process GO:0006665 45 0.032
neuronal action potential GO:0019228 54 0.031
positive regulation of ion transport GO:0043270 65 0.031
adaptive immune response GO:0002250 155 0.031
carbohydrate derivative biosynthetic process GO:1901137 183 0.031
guanosine containing compound catabolic process GO:1901069 144 0.031
regulation of body fluid levels GO:0050878 162 0.031
lymphocyte mediated immunity GO:0002449 139 0.031
gastrulation GO:0007369 116 0.031
negative regulation of apoptotic signaling pathway GO:2001234 104 0.031
cell substrate adhesion GO:0031589 130 0.031
regulation of myeloid cell differentiation GO:0045637 96 0.031
skeletal system morphogenesis GO:0048705 203 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
germ cell development GO:0007281 185 0.031
regulation of inflammatory response GO:0050727 147 0.031
macroautophagy GO:0016236 21 0.031
alpha beta t cell differentiation GO:0046632 69 0.031
t cell differentiation GO:0030217 174 0.031
positive regulation of hydrolase activity GO:0051345 148 0.031
oocyte construction GO:0007308 2 0.030
negative regulation of protein modification process GO:0031400 163 0.030
alpha beta t cell activation GO:0046631 91 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
hemostasis GO:0007599 78 0.030
epidermis development GO:0008544 187 0.030
cellular response to hormone stimulus GO:0032870 150 0.030
muscle cell differentiation GO:0042692 261 0.030
ossification GO:0001503 216 0.030
ubiquitin dependent protein catabolic process GO:0006511 129 0.030
connective tissue development GO:0061448 179 0.030
synapse organization GO:0050808 125 0.030
regulation of ion homeostasis GO:2000021 64 0.030
activation of immune response GO:0002253 138 0.030
regulation of intracellular transport GO:0032386 159 0.030
response to insulin GO:0032868 100 0.030
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.030
response to transforming growth factor beta GO:0071559 88 0.030
regulation of cytoskeleton organization GO:0051493 122 0.030
intracellular distribution of mitochondria GO:0048312 1 0.030
release of sequestered calcium ion into cytosol GO:0051209 42 0.030
organelle fission GO:0048285 170 0.030
regulation of ras protein signal transduction GO:0046578 114 0.029
positive regulation of neuron differentiation GO:0045666 141 0.029
positive regulation of nucleotide metabolic process GO:0045981 114 0.029
regulation of tube size GO:0035150 57 0.029
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.029
regulation of nucleotide metabolic process GO:0006140 169 0.029
peptidyl tyrosine modification GO:0018212 145 0.029
glial cell apoptotic process GO:0034349 3 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.029
response to organic cyclic compound GO:0014070 198 0.029
b cell activation GO:0042113 161 0.029
intestinal epithelial structure maintenance GO:0060729 4 0.029
nucleotide catabolic process GO:0009166 217 0.029
regulation of tumor necrosis factor production GO:0032680 49 0.029
oocyte axis specification GO:0007309 2 0.029
myeloid cell homeostasis GO:0002262 114 0.029
lateral inhibition GO:0046331 1 0.029
regulation of cell size GO:0008361 72 0.028
central nervous system neuron differentiation GO:0021953 162 0.028
cholesterol biosynthetic process GO:0006695 15 0.028
regulation of hormone levels GO:0010817 211 0.028
heterocycle catabolic process GO:0046700 280 0.028
t cell proliferation GO:0042098 120 0.028
positive regulation of protein kinase activity GO:0045860 144 0.028
regulation of autophagy GO:0010506 30 0.028
Fly
morphogenesis of a polarized epithelium GO:0001738 37 0.028
cell maturation GO:0048469 127 0.028
adult locomotory behavior GO:0008344 91 0.028
regulation of proteolysis GO:0030162 164 0.027
regulation of endopeptidase activity GO:0052548 89 0.027
epithelial cell development GO:0002064 159 0.027
single organism cell adhesion GO:0098602 156 0.027
regulation of organ morphogenesis GO:2000027 144 0.027
mitotic cell cycle GO:0000278 195 0.027
Fly
regulation of establishment of protein localization GO:0070201 181 0.027
regulation of metal ion transport GO:0010959 106 0.027
cellular response to molecule of bacterial origin GO:0071219 83 0.027
chromatin organization GO:0006325 206 0.027
response to peptide GO:1901652 136 0.027
mitotic cell cycle process GO:1903047 159 0.027
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.027
phagocytosis GO:0006909 66 0.027
negative regulation of homeostatic process GO:0032845 71 0.027
digestive tract morphogenesis GO:0048546 147 0.027
macromolecule methylation GO:0043414 120 0.027
purine containing compound biosynthetic process GO:0072522 70 0.026
dna recombination GO:0006310 92 0.026
regulation of ras gtpase activity GO:0032318 88 0.026
ribonucleotide biosynthetic process GO:0009260 59 0.026
cytosolic calcium ion homeostasis GO:0051480 70 0.026
response to nutrient levels GO:0031667 109 0.026
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.026
monocarboxylic acid metabolic process GO:0032787 191 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
cell growth GO:0016049 130 0.026
Worm
neuron projection guidance GO:0097485 141 0.026
positive regulation of leukocyte differentiation GO:1902107 86 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
positive regulation of transcription by galactose GO:0000411 1 0.025
neuron migration GO:0001764 122 0.025
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.025
peptidyl serine phosphorylation GO:0018105 74 0.025
Worm
wound healing GO:0042060 157 0.025
sperm capacitation GO:0048240 17 0.025
methylation GO:0032259 134 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
development of primary sexual characteristics GO:0045137 143 0.025
regulation of engulfment of apoptotic cell GO:1901074 2 0.025
purine ribonucleotide biosynthetic process GO:0009152 59 0.025
vascular process in circulatory system GO:0003018 62 0.025
neuron apoptotic process GO:0051402 142 0.025
calcium mediated signaling GO:0019722 46 0.025
regulation of cell adhesion GO:0030155 154 0.025
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.025
phosphatidylinositol phosphorylation GO:0046854 23 0.025
regulation of anion transport GO:0044070 27 0.025
regulation of lipid metabolic process GO:0019216 118 0.025
organophosphate catabolic process GO:0046434 232 0.025
neuromuscular process GO:0050905 99 0.025
response to starvation GO:0042594 65 0.024
endocytosis GO:0006897 168 0.024
monosaccharide metabolic process GO:0005996 106 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
genetic imprinting GO:0071514 27 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
positive regulation of kinase activity GO:0033674 155 0.024
organelle localization GO:0051640 179 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.024
erk1 and erk2 cascade GO:0070371 77 0.024
positive regulation of rac protein signal transduction GO:0035022 1 0.024
positive regulation of organelle organization GO:0010638 128 0.024
calcium ion transport into cytosol GO:0060402 48 0.024
protein acylation GO:0043543 64 0.024
forebrain development GO:0030900 302 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
sensory perception GO:0007600 245 0.024
myeloid cell differentiation GO:0030099 233 0.024
sterol metabolic process GO:0016125 58 0.024
regulation of myeloid leukocyte differentiation GO:0002761 58 0.024
regulation of lymphocyte proliferation GO:0050670 117 0.024
b cell activation involved in immune response GO:0002312 50 0.024
stem cell development GO:0048864 219 0.024
mechanoreceptor differentiation GO:0042490 67 0.023
organic hydroxy compound biosynthetic process GO:1901617 77 0.023
positive regulation of map kinase activity GO:0043406 84 0.023
cellular response to organic cyclic compound GO:0071407 87 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.023
cellular response to biotic stimulus GO:0071216 92 0.023
Human
response to hypoxia GO:0001666 58 0.023
blood vessel morphogenesis GO:0048514 285 0.023
glycerolipid metabolic process GO:0046486 122 0.023
regulation of ossification GO:0030278 112 0.023
positive regulation of defense response GO:0031349 124 0.023
positive regulation of gtpase activity GO:0043547 85 0.023
adult behavior GO:0030534 135 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
positive regulation of intracellular transport GO:0032388 70 0.022
learning GO:0007612 98 0.022
positive regulation of protein catabolic process GO:0045732 60 0.022
cholesterol metabolic process GO:0008203 56 0.022
developmental cell growth GO:0048588 84 0.022
cytokine mediated signaling pathway GO:0019221 115 0.022
carbon catabolite activation of transcription GO:0045991 4 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
covalent chromatin modification GO:0016569 163 0.022
protein secretion GO:0009306 111 0.022
myeloid leukocyte activation GO:0002274 83 0.022
actin filament organization GO:0007015 113 0.022
cellular response to starvation GO:0009267 57 0.022
tumor necrosis factor production GO:0032640 50 0.022
camp biosynthetic process GO:0006171 31 0.022
regulation of response to wounding GO:1903034 189 0.022
epithelial tube formation GO:0072175 130 0.022
negative regulation of lymphocyte activation GO:0051250 91 0.022
negative regulation of synapse assembly GO:0051964 3 0.022
antigen receptor mediated signaling pathway GO:0050851 64 0.022
negative regulation of transferase activity GO:0051348 85 0.022
visual behavior GO:0007632 45 0.022
glycoprotein biosynthetic process GO:0009101 89 0.022
neural tube formation GO:0001841 108 0.022
limb development GO:0060173 166 0.021
ribose phosphate biosynthetic process GO:0046390 59 0.021
cyclic nucleotide metabolic process GO:0009187 59 0.021
male sex differentiation GO:0046661 109 0.021
stem cell differentiation GO:0048863 268 0.021
regulation of multi organism process GO:0043900 111 0.021
bone remodeling GO:0046849 53 0.021
dna methylation GO:0006306 43 0.021

Eif2ak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.060
disease of cellular proliferation DOID:14566 0 0.060
organ system cancer DOID:0050686 0 0.060
disease of metabolism DOID:0014667 0 0.051
immune system disease DOID:2914 0 0.030
disease of anatomical entity DOID:7 0 0.030
hematopoietic system disease DOID:74 0 0.030