Mus musculus

68 known processes

Eif2c1

eukaryotic translation initiation factor 2C, 1

(Aliases: Ago1)

Eif2c1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene silencing by mirna GO:0035195 10 0.961
Human Fly
positive regulation of gene silencing by mirna GO:2000637 1 0.708
posttranscriptional gene silencing GO:0016441 10 0.506
Human Fly
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.448
positive regulation of posttranscriptional gene silencing GO:0060148 1 0.360
cellular macromolecule catabolic process GO:0044265 206 0.345
Human Mouse Fly
protein polyubiquitination GO:0000209 33 0.318
negative regulation of cellular protein metabolic process GO:0032269 247 0.296
Human Fly
embryonic epithelial tube formation GO:0001838 130 0.292
posttranscriptional gene silencing by rna GO:0035194 10 0.279
Human Fly
ubiquitin dependent protein catabolic process GO:0006511 129 0.276
actin modification GO:0030047 1 0.269
gene silencing GO:0016458 38 0.261
Human Mouse Fly
cellular response to dna damage stimulus GO:0006974 207 0.253
viral gene expression GO:0019080 3 0.247
negative regulation of protein metabolic process GO:0051248 282 0.243
Human Fly
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.234
neural tube development GO:0021915 160 0.234
epithelial tube formation GO:0072175 130 0.219
macromolecule catabolic process GO:0009057 281 0.218
Human Mouse Fly
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.206
negative regulation of cell proliferation GO:0008285 296 0.204
protein modification by small protein conjugation or removal GO:0070647 207 0.203
intrinsic apoptotic signaling pathway GO:0097193 132 0.202
negative regulation of viral transcription GO:0032897 3 0.193
modification dependent macromolecule catabolic process GO:0043632 133 0.188
regulation of viral release from host cell GO:1902186 6 0.187
innate immune response GO:0045087 157 0.186
morphogenesis of embryonic epithelium GO:0016331 159 0.185
epithelial tube morphogenesis GO:0060562 303 0.183
regulation of cellular response to stress GO:0080135 159 0.180
positive regulation of cell development GO:0010720 237 0.179
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.178
posttranscriptional regulation of gene expression GO:0010608 155 0.175
Human Fly
neural tube formation GO:0001841 108 0.170
negative regulation of multi organism process GO:0043901 68 0.168
translation GO:0006412 93 0.164
Human Fly
neural tube closure GO:0001843 90 0.159
regulation of cell cycle GO:0051726 281 0.157
response to uv GO:0009411 44 0.156
apoptotic signaling pathway GO:0097190 306 0.153
viral process GO:0016032 41 0.149
response to light stimulus GO:0009416 135 0.145
cellular protein catabolic process GO:0044257 155 0.144
stem cell proliferation GO:0072089 117 0.140
tube formation GO:0035148 140 0.139
neural precursor cell proliferation GO:0061351 121 0.137
actin cytoskeleton organization GO:0030036 220 0.135
regulation of multi organism process GO:0043900 111 0.135
mirna metabolic process GO:0010586 10 0.131
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.131
tube closure GO:0060606 91 0.125
positive regulation of nervous system development GO:0051962 221 0.124
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.123
protein modification by small protein conjugation GO:0032446 187 0.119
regulation of neural precursor cell proliferation GO:2000177 70 0.118
primary neural tube formation GO:0014020 95 0.118
cell cycle g1 s phase transition GO:0044843 57 0.116
mitotic cell cycle process GO:1903047 159 0.115
response to radiation GO:0009314 165 0.113
protein catabolic process GO:0030163 221 0.113
neuron death GO:0070997 154 0.110
neuron apoptotic process GO:0051402 142 0.108
regulation of proteolysis GO:0030162 164 0.107
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.106
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.104
regulation of translation GO:0006417 71 0.104
Human Fly
negative regulation of intracellular signal transduction GO:1902532 167 0.104
mitotic cell cycle GO:0000278 195 0.103
viral transcription GO:0019083 3 0.100
regulation of neuron differentiation GO:0045664 281 0.098
regulation of neuron death GO:1901214 134 0.096
protein ubiquitination GO:0016567 171 0.094
positive regulation of neuron differentiation GO:0045666 141 0.093
small gtpase mediated signal transduction GO:0007264 97 0.093
regulation of neuron apoptotic process GO:0043523 122 0.091
regulation of cellular catabolic process GO:0031329 242 0.090
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.088
nucleobase containing small molecule metabolic process GO:0055086 352 0.087
g1 s transition of mitotic cell cycle GO:0000082 57 0.086
regulation of response to dna damage stimulus GO:2001020 34 0.085
positive regulation of protein catabolic process GO:0045732 60 0.085
cell type specific apoptotic process GO:0097285 268 0.084
forebrain development GO:0030900 302 0.083
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.077
negative regulation of fibroblast proliferation GO:0048147 14 0.077
fat cell differentiation GO:0045444 160 0.076
viral life cycle GO:0019058 36 0.076
ras protein signal transduction GO:0007265 77 0.075
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.074
positive regulation of protein modification process GO:0031401 299 0.072
response to fibroblast growth factor GO:0071774 47 0.071
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 14 0.070
nucleotide metabolic process GO:0009117 332 0.069
ribose phosphate metabolic process GO:0019693 291 0.068
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.067
nucleoside metabolic process GO:0009116 246 0.066
regulation of protein catabolic process GO:0042176 108 0.065
negative regulation of cellular component organization GO:0051129 194 0.065
positive regulation of proteolysis GO:0045862 85 0.063
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.062
amine metabolic process GO:0009308 45 0.062
aromatic compound catabolic process GO:0019439 286 0.061
Human Mouse Fly
positive regulation of cell growth GO:0030307 33 0.061
ribonucleotide metabolic process GO:0009259 291 0.060
fibroblast proliferation GO:0048144 35 0.059
ribonucleoside metabolic process GO:0009119 245 0.059
negative regulation of viral process GO:0048525 23 0.058
cellular ketone metabolic process GO:0042180 84 0.057
purine nucleoside metabolic process GO:0042278 241 0.057
regulation of fibroblast proliferation GO:0048145 34 0.056
nucleoside phosphate metabolic process GO:0006753 338 0.056
nucleotide catabolic process GO:0009166 217 0.056
i kappab kinase nf kappab signaling GO:0007249 85 0.056
positive regulation of cell motility GO:2000147 116 0.056
chromatin organization GO:0006325 206 0.056
negative regulation of viral release from host cell GO:1902187 6 0.054
regulation of transferase activity GO:0051338 263 0.054
positive regulation of cell migration GO:0030335 109 0.053
purine nucleotide metabolic process GO:0006163 302 0.053
ribonucleoside triphosphate catabolic process GO:0009203 199 0.052
purine containing compound metabolic process GO:0072521 311 0.052
regulation of cell migration GO:0030334 219 0.052
positive regulation of growth GO:0045927 104 0.051
Worm
regulation of purine nucleotide catabolic process GO:0033121 122 0.050
viral release from host cell GO:0019076 6 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.050
negative regulation of translation involved in gene silencing by mirna GO:0035278 2 0.049
Human
response to growth factor GO:0070848 198 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.047
Human Mouse Fly
regulation of protein ubiquitination GO:0031396 52 0.047
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
regulation of translation ncrna mediated GO:0045974 2 0.046
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.046
positive regulation of protein ubiquitination GO:0031398 27 0.046
purine nucleoside triphosphate metabolic process GO:0009144 226 0.046
cellular amino acid metabolic process GO:0006520 103 0.046
nucleoside phosphate catabolic process GO:1901292 222 0.045
response to tumor necrosis factor GO:0034612 26 0.044
regulation of cell motility GO:2000145 236 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.044
rho protein signal transduction GO:0007266 32 0.044
regulation of cell growth GO:0001558 91 0.044
positive regulation of cell cycle GO:0045787 92 0.042
cell growth GO:0016049 130 0.042
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.042
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.040
negative regulation of nervous system development GO:0051961 156 0.040
negative regulation of molecular function GO:0044092 258 0.039
regulation of protein kinase activity GO:0045859 232 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
heterocycle catabolic process GO:0046700 280 0.038
Human Mouse Fly
glycosyl compound metabolic process GO:1901657 246 0.037
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.037
germ cell development GO:0007281 185 0.036
Worm Fly
positive regulation of cellular catabolic process GO:0031331 148 0.036
Mouse
dna metabolic process GO:0006259 303 0.036
gland development GO:0048732 330 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
Human Mouse Fly
regulation of mitotic cell cycle GO:0007346 126 0.035
developmental maturation GO:0021700 193 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
regulation of purine nucleotide metabolic process GO:1900542 169 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.034
regulation of cell cycle process GO:0010564 160 0.034
nucleoside triphosphate catabolic process GO:0009143 205 0.033
cellular amine metabolic process GO:0044106 44 0.033
regulation of organelle organization GO:0033043 289 0.033
negative regulation of synapse assembly GO:0051964 3 0.033
nucleoside catabolic process GO:0009164 206 0.033
endocytosis GO:0006897 168 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.032
regulation of gene silencing by rna GO:0060966 5 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
purine containing compound catabolic process GO:0072523 213 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
chromatin modification GO:0016568 187 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
covalent chromatin modification GO:0016569 163 0.030
positive regulation of gtp catabolic process GO:0033126 85 0.029
regulation of nucleotide metabolic process GO:0006140 169 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
guanosine containing compound catabolic process GO:1901069 144 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
purine ribonucleoside catabolic process GO:0046130 205 0.028
organophosphate catabolic process GO:0046434 232 0.028
cilium morphogenesis GO:0060271 102 0.028
muscle tissue development GO:0060537 308 0.027
regulation of protein localization GO:0032880 231 0.027
regulation of mitotic cell cycle phase transition GO:1901990 73 0.027
rhythmic process GO:0048511 174 0.027
circulatory system process GO:0003013 197 0.026
immune effector process GO:0002252 321 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
nucleoside bisphosphate biosynthetic process GO:0033866 6 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.025
spermatid development GO:0007286 108 0.025
positive regulation of nucleoside metabolic process GO:0045979 91 0.025
male gamete generation GO:0048232 285 0.025
regulation of kinase activity GO:0043549 249 0.025
compound eye development GO:0048749 1 0.025
gtp catabolic process GO:0006184 143 0.025
nitrogen compound transport GO:0071705 271 0.024
gtp metabolic process GO:0046039 144 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
camera type eye development GO:0043010 266 0.024
negative regulation of cell cycle phase transition GO:1901988 48 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
cytokine production GO:0001816 319 0.024
mapk cascade GO:0000165 281 0.023
lung development GO:0030324 164 0.023
regulation of ras gtpase activity GO:0032318 88 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
response to organonitrogen compound GO:0010243 246 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
oocyte axis specification GO:0007309 2 0.023
sensory perception GO:0007600 245 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
negative regulation of protein modification process GO:0031400 163 0.023
positive regulation of hydrolase activity GO:0051345 148 0.023
axonogenesis GO:0007409 274 0.023
regulation of membrane potential GO:0042391 192 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
protein targeting GO:0006605 143 0.022
inflammatory response GO:0006954 244 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
regulation of posttranscriptional gene silencing GO:0060147 5 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
regulation of histone modification GO:0031056 56 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
regulation of cell projection organization GO:0031344 206 0.022
organelle fission GO:0048285 170 0.022
regionalization GO:0003002 337 0.021
Fly
histone modification GO:0016570 159 0.021
skeletal system development GO:0001501 356 0.021
cytoplasmic transport GO:0016482 234 0.021
cell division GO:0051301 120 0.021
spermatid differentiation GO:0048515 115 0.021
negative regulation of cell development GO:0010721 169 0.021
regulation of hydrolase activity GO:0051336 246 0.021
cellular lipid metabolic process GO:0044255 323 0.021
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.021
ion transmembrane transport GO:0034220 361 0.021
spermatogenesis GO:0007283 284 0.021
organelle assembly GO:0070925 177 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
response to organic cyclic compound GO:0014070 198 0.020
Fly
regulation of cellular component size GO:0032535 121 0.020
respiratory tube development GO:0030323 167 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
leukocyte differentiation GO:0002521 342 0.020
intracellular protein transport GO:0006886 204 0.020
endomembrane system organization GO:0010256 147 0.019
regulation of hormone levels GO:0010817 211 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.019
learning or memory GO:0007611 148 0.019
Fly
negative regulation of immune system process GO:0002683 209 0.019
rap protein signal transduction GO:0032486 3 0.019
negative regulation of organelle organization GO:0010639 90 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
microtubule based process GO:0007017 236 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
membrane organization GO:0061024 245 0.018
negative regulation of response to dna damage stimulus GO:2001021 10 0.018
t cell differentiation GO:0030217 174 0.018
rna processing GO:0006396 105 0.018
Mouse Fly
response to sterol GO:0036314 4 0.018
muscle cell differentiation GO:0042692 261 0.018
metal ion homeostasis GO:0055065 189 0.018
regulation of cytokine production GO:0001817 266 0.018
peptidyl lysine modification GO:0018205 77 0.018
positive regulation of gtpase activity GO:0043547 85 0.018
actin ubiquitination GO:0007014 1 0.018
macromolecular complex disassembly GO:0032984 43 0.018
positive regulation of kinase activity GO:0033674 155 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
methylation GO:0032259 134 0.017
skeletal muscle organ development GO:0060538 163 0.017
regulation of neuron projection development GO:0010975 169 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
purine nucleotide biosynthetic process GO:0006164 65 0.017
nuclear division GO:0000280 158 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
cellular response to lipid GO:0071396 145 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
regulation of chromosome organization GO:0033044 83 0.017
positive regulation of dna templated transcription elongation GO:0032786 2 0.017
transmembrane transport GO:0055085 412 0.017
regulation of mapk cascade GO:0043408 248 0.017
regulation of intracellular transport GO:0032386 159 0.017
dendrite development GO:0016358 115 0.017
oocyte construction GO:0007308 2 0.017
protein maturation GO:0051604 176 0.017
positive regulation of transferase activity GO:0051347 167 0.017
response to oxidative stress GO:0006979 123 0.017
cell fate commitment GO:0045165 210 0.016
Fly
regulation of t cell activation GO:0050863 170 0.016
cation transport GO:0006812 399 0.016
regulation of cell activation GO:0050865 289 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
regulation of cell cycle phase transition GO:1901987 77 0.016
peptidyl amino acid modification GO:0018193 336 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
epithelial cell development GO:0002064 159 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
Fly
peptide secretion GO:0002790 114 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
anion transport GO:0006820 177 0.016
telencephalon development GO:0021537 186 0.015
oxidation reduction process GO:0055114 342 0.015
synaptic transmission GO:0007268 329 0.015
glycerolipid metabolic process GO:0046486 122 0.015
organelle localization GO:0051640 179 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
amide transport GO:0042886 138 0.015
blood circulation GO:0008015 195 0.015
notch signaling pathway GO:0007219 71 0.015
maintenance of location GO:0051235 89 0.015
cation transmembrane transport GO:0098655 266 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
mesonephros development GO:0001823 97 0.015
digestive system development GO:0055123 200 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
regulation of ion transport GO:0043269 215 0.015
energy derivation by oxidation of organic compounds GO:0015980 77 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
neuronal action potential GO:0019228 54 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
stem cell differentiation GO:0048863 268 0.015
Fly
embryonic organ morphogenesis GO:0048562 276 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
regulation of chromatin modification GO:1903308 57 0.014
regulation of response to wounding GO:1903034 189 0.014
carbohydrate homeostasis GO:0033500 128 0.014
habituation GO:0046959 3 0.014
Fly
respiratory system development GO:0060541 190 0.014
multicellular organismal signaling GO:0035637 91 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
macromolecule methylation GO:0043414 120 0.014
lipid localization GO:0010876 126 0.014
cell cycle checkpoint GO:0000075 47 0.014
cellular homeostasis GO:0019725 240 0.013
asymmetric stem cell division GO:0098722 3 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
meiotic nuclear division GO:0007126 115 0.013
protein localization to organelle GO:0033365 185 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
regulation of secretion GO:0051046 274 0.013
stress activated protein kinase signaling cascade GO:0031098 81 0.013
phospholipid metabolic process GO:0006644 87 0.013
wnt signaling pathway GO:0016055 188 0.013
defense response to other organism GO:0098542 197 0.013
dephosphorylation GO:0016311 129 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
cell adhesion GO:0007155 329 0.013
response to nutrient levels GO:0031667 109 0.013
regulation of anatomical structure size GO:0090066 178 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
adult behavior GO:0030534 135 0.013
response to extracellular stimulus GO:0009991 127 0.013
nuclear transport GO:0051169 139 0.013
positive regulation of neuron projection development GO:0010976 79 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
positive regulation of secretion GO:0051047 130 0.013
microtubule based movement GO:0007018 84 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
homeostasis of number of cells GO:0048872 210 0.013
circadian rhythm GO:0007623 114 0.013
action potential GO:0001508 78 0.013
wound healing GO:0042060 157 0.013
cellular protein complex assembly GO:0043623 116 0.013
insulin secretion GO:0030073 89 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
digestive tract development GO:0048565 190 0.012
regulation of ossification GO:0030278 112 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
negative regulation of cell cycle GO:0045786 123 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
response to peptide hormone GO:0043434 127 0.012
muscle cell development GO:0055001 133 0.012
cation homeostasis GO:0055080 212 0.012
hormone secretion GO:0046879 128 0.012
peptide hormone secretion GO:0030072 109 0.012
t cell activation GO:0042110 289 0.012
response to inorganic substance GO:0010035 96 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
cell maturation GO:0048469 127 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
protein localization to nucleus GO:0034504 121 0.012
plasma membrane organization GO:0007009 90 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
cognition GO:0050890 149 0.012
Fly
lymphocyte differentiation GO:0030098 242 0.012
lipid biosynthetic process GO:0008610 179 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
regulation of inflammatory response GO:0050727 147 0.012
chemotaxis GO:0006935 247 0.012
fertilization GO:0009566 127 0.012
mrna metabolic process GO:0016071 84 0.012
Human Mouse Fly
regulation of innate immune response GO:0045088 91 0.012
response to lipopolysaccharide GO:0032496 128 0.012
lymphocyte proliferation GO:0046651 164 0.012
cytokinetic process GO:0032506 2 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
peptide transport GO:0015833 133 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
regulation of cell adhesion GO:0030155 154 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
regulation of defense response GO:0031347 233 0.012
regulation of homeostatic process GO:0032844 182 0.012
jnk cascade GO:0007254 72 0.012
cellular response to external stimulus GO:0071496 88 0.011
regulation of lymphocyte anergy GO:0002911 4 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
bmp signaling pathway GO:0030509 93 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
negative regulation of transferase activity GO:0051348 85 0.011
positive regulation of cell death GO:0010942 224 0.011
transmission of nerve impulse GO:0019226 76 0.011
protein processing GO:0016485 163 0.011
lateral inhibition GO:0046331 1 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
protein alkylation GO:0008213 81 0.011
positive regulation of rho gtpase activity GO:0032321 41 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
regulation of secretion by cell GO:1903530 249 0.011
glucose homeostasis GO:0042593 128 0.011
negative regulation of growth GO:0045926 99 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
appendage development GO:0048736 166 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of feeding behavior GO:0060259 3 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
positive regulation of organelle organization GO:0010638 128 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
organ growth GO:0035265 117 0.011
adaptive immune response GO:0002250 155 0.011
locomotory behavior GO:0007626 195 0.011
pharynx development GO:0060465 1 0.011
small molecule biosynthetic process GO:0044283 132 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
ureteric bud development GO:0001657 94 0.011
negative regulation of cell activation GO:0050866 111 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
regulation of protein transport GO:0051223 163 0.011
limb development GO:0060173 166 0.011
limbic system development GO:0021761 72 0.011
gonad development GO:0008406 141 0.011
Worm
b cell activation GO:0042113 161 0.011
regulation of t cell proliferation GO:0042129 92 0.011
mitotic cell cycle checkpoint GO:0007093 31 0.011
carbohydrate metabolic process GO:0005975 230 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of protein processing GO:0070613 96 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
regulation of bmp signaling pathway GO:0030510 60 0.011
angiogenesis GO:0001525 201 0.011

Eif2c1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.480
disease of anatomical entity DOID:7 0 0.480
musculoskeletal system disease DOID:17 0 0.480
muscle tissue disease DOID:66 0 0.419
myopathy DOID:423 0 0.138
muscular dystrophy DOID:9884 0 0.113
limb girdle muscular dystrophy DOID:11724 0 0.113
nervous system disease DOID:863 0 0.031
central nervous system disease DOID:331 0 0.021
disease of cellular proliferation DOID:14566 0 0.018
disease of metabolism DOID:0014667 0 0.016
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
inherited metabolic disorder DOID:655 0 0.011