Mus musculus

0 known processes

Eif2s3y

eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked

(Aliases: Spy,Eif-2gy,Tfy)

Eif2s3y biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound catabolic process GO:0019439 286 0.125
covalent chromatin modification GO:0016569 163 0.108
purine containing compound metabolic process GO:0072521 311 0.105
spermatid differentiation GO:0048515 115 0.105
heterocycle catabolic process GO:0046700 280 0.102
nucleobase containing small molecule metabolic process GO:0055086 352 0.095
histone lysine demethylation GO:0070076 13 0.093
purine ribonucleotide metabolic process GO:0009150 290 0.091
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.091
nucleoside triphosphate catabolic process GO:0009143 205 0.090
purine nucleotide metabolic process GO:0006163 302 0.083
cellular nitrogen compound catabolic process GO:0044270 280 0.080
gene silencing GO:0016458 38 0.079
histone modification GO:0016570 159 0.078
ribonucleotide catabolic process GO:0009261 208 0.077
ribonucleotide metabolic process GO:0009259 291 0.076
ribonucleoside triphosphate metabolic process GO:0009199 220 0.075
purine nucleotide catabolic process GO:0006195 211 0.075
nucleoside triphosphate metabolic process GO:0009141 230 0.074
protein dealkylation GO:0008214 13 0.074
nucleoside phosphate metabolic process GO:0006753 338 0.070
nucleoside metabolic process GO:0009116 246 0.070
ribonucleoside metabolic process GO:0009119 245 0.070
organic cyclic compound catabolic process GO:1901361 295 0.068
glycosyl compound metabolic process GO:1901657 246 0.064
purine nucleoside triphosphate metabolic process GO:0009144 226 0.063
carbohydrate derivative catabolic process GO:1901136 231 0.063
purine ribonucleoside metabolic process GO:0046128 241 0.063
purine ribonucleotide catabolic process GO:0009154 208 0.062
purine nucleoside metabolic process GO:0042278 241 0.061
purine ribonucleoside catabolic process GO:0046130 205 0.061
organelle fission GO:0048285 170 0.058
chromatin modification GO:0016568 187 0.057
nucleotide catabolic process GO:0009166 217 0.054
male gamete generation GO:0048232 285 0.054
spermatogenesis GO:0007283 284 0.054
purine nucleoside catabolic process GO:0006152 205 0.053
cardiac muscle cell contraction GO:0086003 7 0.051
purine containing compound catabolic process GO:0072523 213 0.050
cellular amine metabolic process GO:0044106 44 0.050
regionalization GO:0003002 337 0.050
demethylation GO:0070988 23 0.049
protein demethylation GO:0006482 13 0.049
cellular amino acid metabolic process GO:0006520 103 0.049
ribonucleoside monophosphate metabolic process GO:0009161 80 0.048
ribonucleoside catabolic process GO:0042454 206 0.048
purine nucleoside triphosphate catabolic process GO:0009146 203 0.047
ribonucleoside triphosphate catabolic process GO:0009203 199 0.047
muscle system process GO:0003012 141 0.047
spermatid development GO:0007286 108 0.046
amine metabolic process GO:0009308 45 0.046
posttranscriptional regulation of gene expression GO:0010608 155 0.046
atp metabolic process GO:0046034 75 0.045
nucleoside catabolic process GO:0009164 206 0.044
mrna metabolic process GO:0016071 84 0.044
blood circulation GO:0008015 195 0.044
oxidation reduction process GO:0055114 342 0.043
striated muscle tissue development GO:0014706 293 0.043
regulation of chromatin silencing GO:0031935 2 0.042
glycosyl compound catabolic process GO:1901658 206 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.041
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.041
rna interference GO:0016246 2 0.041
transmembrane transport GO:0055085 412 0.041
organonitrogen compound catabolic process GO:1901565 264 0.041
cellular ketone metabolic process GO:0042180 84 0.040
ribose phosphate metabolic process GO:0019693 291 0.039
ribonucleoprotein complex disassembly GO:0032988 3 0.038
nucleotide metabolic process GO:0009117 332 0.038
peptidyl amino acid modification GO:0018193 336 0.038
striated muscle contraction GO:0006941 45 0.037
ribonucleoside monophosphate catabolic process GO:0009158 57 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
nuclear division GO:0000280 158 0.036
tube closure GO:0060606 91 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
multicellular organism growth GO:0035264 161 0.036
gene silencing by rna GO:0031047 19 0.035
purine nucleoside monophosphate metabolic process GO:0009126 81 0.034
circadian regulation of gene expression GO:0032922 48 0.033
muscle cell differentiation GO:0042692 261 0.033
purine nucleoside monophosphate catabolic process GO:0009128 58 0.033
translation GO:0006412 93 0.033
mrna splicing via spliceosome GO:0000398 43 0.032
rna processing GO:0006396 105 0.032
macromolecule catabolic process GO:0009057 281 0.032
rna splicing GO:0008380 54 0.032
heart process GO:0003015 94 0.031
embryonic organ morphogenesis GO:0048562 276 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
posttranscriptional gene silencing GO:0016441 10 0.030
regulation of organelle organization GO:0033043 289 0.030
germ cell development GO:0007281 185 0.029
cation transport GO:0006812 399 0.029
cellular lipid metabolic process GO:0044255 323 0.029
nucleoside monophosphate metabolic process GO:0009123 85 0.029
cytoplasmic transport GO:0016482 234 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.028
histone h3 k36 demethylation GO:0070544 2 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
mitotic cell cycle process GO:1903047 159 0.028
muscle contraction GO:0006936 101 0.028
negative regulation of molecular function GO:0044092 258 0.027
muscle tissue development GO:0060537 308 0.027
ion transmembrane transport GO:0034220 361 0.027
segmentation GO:0035282 93 0.027
morphogenesis of embryonic epithelium GO:0016331 159 0.026
mitotic cell cycle GO:0000278 195 0.026
apoptotic signaling pathway GO:0097190 306 0.026
mrna processing GO:0006397 63 0.026
macromolecular complex disassembly GO:0032984 43 0.026
embryonic epithelial tube formation GO:0001838 130 0.025
posttranscriptional gene silencing by rna GO:0035194 10 0.025
regulation of hydrolase activity GO:0051336 246 0.025
wnt signaling pathway GO:0016055 188 0.025
heart contraction GO:0060047 93 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.024
nitrogen compound transport GO:0071705 271 0.024
cellular response to oxidative stress GO:0034599 76 0.024
response to reactive oxygen species GO:0000302 56 0.024
digestive tract development GO:0048565 190 0.024
mitotic sister chromatid segregation GO:0000070 14 0.024
translational initiation GO:0006413 24 0.024
anion transport GO:0006820 177 0.023
response to organonitrogen compound GO:0010243 246 0.023
response to inorganic substance GO:0010035 96 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
small molecule biosynthetic process GO:0044283 132 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
actin mediated cell contraction GO:0070252 15 0.022
cation transmembrane transport GO:0098655 266 0.022
intracellular protein transport GO:0006886 204 0.022
regulation of membrane potential GO:0042391 192 0.022
rhythmic process GO:0048511 174 0.022
cellular homeostasis GO:0019725 240 0.021
spliceosomal complex disassembly GO:0000390 1 0.021
endomembrane system organization GO:0010256 147 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
cellular response to dna damage stimulus GO:0006974 207 0.021
cell type specific apoptotic process GO:0097285 268 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.020
organic acid transport GO:0015849 101 0.020
primary neural tube formation GO:0014020 95 0.020
regulation of cell cycle GO:0051726 281 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
protein catabolic process GO:0030163 221 0.019
cardiac muscle tissue development GO:0048738 130 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
mitotic nuclear division GO:0007067 48 0.019
membrane organization GO:0061024 245 0.019
lipid biosynthetic process GO:0008610 179 0.019
divalent inorganic cation transport GO:0072511 178 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
cellular response to lipid GO:0071396 145 0.019
circadian rhythm GO:0007623 114 0.019
synaptic transmission GO:0007268 329 0.019
locomotory behavior GO:0007626 195 0.018
circulatory system process GO:0003013 197 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
organic anion transport GO:0015711 137 0.018
cardiocyte differentiation GO:0035051 87 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
rna splicing via transesterification reactions GO:0000375 43 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
nucleoside monophosphate catabolic process GO:0009125 59 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
regulation of protein localization GO:0032880 231 0.017
mapk cascade GO:0000165 281 0.017
female gamete generation GO:0007292 74 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
leukocyte differentiation GO:0002521 342 0.017
carboxylic acid transport GO:0046942 100 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of kinase activity GO:0043549 249 0.017
positive regulation of protein modification process GO:0031401 299 0.017
sensory perception GO:0007600 245 0.017
cellular macromolecule catabolic process GO:0044265 206 0.016
somitogenesis GO:0001756 69 0.016
protein ubiquitination GO:0016567 171 0.016
protein localization to organelle GO:0033365 185 0.016
mesoderm development GO:0007498 100 0.016
positive regulation of cell death GO:0010942 224 0.016
negative regulation of organelle organization GO:0010639 90 0.016
regulation of neuron differentiation GO:0045664 281 0.016
regulation of cell projection organization GO:0031344 206 0.016
cellular chemical homeostasis GO:0055082 215 0.016
regulation of chromosome organization GO:0033044 83 0.016
sequestering of calcium ion GO:0051208 18 0.016
regulation of secretion by cell GO:1903530 249 0.016
response to lipopolysaccharide GO:0032496 128 0.016
carbohydrate metabolic process GO:0005975 230 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
divalent metal ion transport GO:0070838 172 0.016
regulation of chromatin modification GO:1903308 57 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
regulation of cell activation GO:0050865 289 0.016
cellular protein complex assembly GO:0043623 116 0.016
organophosphate catabolic process GO:0046434 232 0.015
axonogenesis GO:0007409 274 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of hormone levels GO:0010817 211 0.015
forebrain development GO:0030900 302 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
response to acid chemical GO:0001101 111 0.015
response to oxidative stress GO:0006979 123 0.015
regulation of ion transport GO:0043269 215 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
organic acid biosynthetic process GO:0016053 86 0.015
organelle localization GO:0051640 179 0.015
organelle assembly GO:0070925 177 0.015
regulation of secretion GO:0051046 274 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
cytokine production GO:0001816 319 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
regulation of transmembrane transport GO:0034762 128 0.015
cardiac muscle cell differentiation GO:0055007 69 0.015
mitochondrion distribution GO:0048311 4 0.015
inflammatory response GO:0006954 244 0.015
response to organic cyclic compound GO:0014070 198 0.014
negative regulation of neuron death GO:1901215 98 0.014
sensory organ morphogenesis GO:0090596 242 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
positive regulation of cell development GO:0010720 237 0.014
oogenesis GO:0048477 56 0.014
respiratory system process GO:0003016 25 0.014
cellular protein catabolic process GO:0044257 155 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
nuclear transport GO:0051169 139 0.014
stem cell differentiation GO:0048863 268 0.014
alcohol metabolic process GO:0006066 116 0.014
multicellular organismal signaling GO:0035637 91 0.014
negative regulation of hydrolase activity GO:0051346 71 0.014
camera type eye development GO:0043010 266 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
response to extracellular stimulus GO:0009991 127 0.014
positive regulation of nervous system development GO:0051962 221 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
glucose homeostasis GO:0042593 128 0.014
meiotic cell cycle GO:0051321 122 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
maintenance of location GO:0051235 89 0.014
negative regulation of protein modification process GO:0031400 163 0.014
response to radiation GO:0009314 165 0.014
carbohydrate homeostasis GO:0033500 128 0.014
chromatin organization GO:0006325 206 0.014
mitochondrion organization GO:0007005 134 0.014
skeletal system development GO:0001501 356 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
respiratory system development GO:0060541 190 0.014
regulation of proteolysis GO:0030162 164 0.014
positive regulation of apoptotic process GO:0043065 217 0.013
negative regulation of immune system process GO:0002683 209 0.013
sister chromatid segregation GO:0000819 20 0.013
protein targeting GO:0006605 143 0.013
anatomical structure homeostasis GO:0060249 145 0.013
response to growth factor GO:0070848 198 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
homeostasis of number of cells GO:0048872 210 0.013
meiotic nuclear division GO:0007126 115 0.013
response to nutrient levels GO:0031667 109 0.013
fertilization GO:0009566 127 0.013
striated muscle myosin thick filament assembly GO:0071688 1 0.013
regulation of transferase activity GO:0051338 263 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
neuron apoptotic process GO:0051402 142 0.013
fatty acid metabolic process GO:0006631 121 0.013
immune effector process GO:0002252 321 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
sequestering of metal ion GO:0051238 19 0.013
nucleocytoplasmic transport GO:0006913 139 0.012
lipid transport GO:0006869 98 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of protein kinase activity GO:0045859 232 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
microtubule based process GO:0007017 236 0.012
response to light stimulus GO:0009416 135 0.012
positive regulation of kinase activity GO:0033674 155 0.012
myosin filament assembly GO:0031034 2 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
action potential GO:0001508 78 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
neuron death GO:0070997 154 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
chromosome segregation GO:0007059 48 0.012
regulation of chromatin organization GO:1902275 57 0.012
cellular ion homeostasis GO:0006873 165 0.012
actin filament based movement GO:0030048 23 0.012
gland development GO:0048732 330 0.012
cardiac muscle contraction GO:0060048 32 0.012
histone demethylation GO:0016577 13 0.012
ras protein signal transduction GO:0007265 77 0.012
regulation of protein catabolic process GO:0042176 108 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of defense response GO:0031347 233 0.012
endocytosis GO:0006897 168 0.012
asymmetric stem cell division GO:0098722 3 0.012
organic hydroxy compound transport GO:0015850 93 0.012
regulation of anatomical structure size GO:0090066 178 0.012
protein maturation GO:0051604 176 0.012
cell adhesion GO:0007155 329 0.012
regulation of homeostatic process GO:0032844 182 0.012
positive regulation of organelle organization GO:0010638 128 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
tissue homeostasis GO:0001894 115 0.012
compound eye development GO:0048749 1 0.012
cation homeostasis GO:0055080 212 0.012
modification dependent protein catabolic process GO:0019941 133 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
renal system development GO:0072001 225 0.011
protein import GO:0017038 101 0.011
respiratory tube development GO:0030323 167 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
t cell activation GO:0042110 289 0.011
regulation of neuron death GO:1901214 134 0.011
endothelium development GO:0003158 45 0.011
protein processing GO:0016485 163 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
regulation of cell migration GO:0030334 219 0.011
epithelial tube formation GO:0072175 130 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
positive regulation of secretion GO:0051047 130 0.011
neural tube formation GO:0001841 108 0.011
transmission of nerve impulse GO:0019226 76 0.011
regulation of cytokine production GO:0001817 266 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
lung development GO:0030324 164 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of intracellular transport GO:0032386 159 0.011
negative regulation of cell development GO:0010721 169 0.011
meiosis i GO:0007127 60 0.011
urogenital system development GO:0001655 261 0.011
retina development in camera type eye GO:0060041 119 0.011
dna metabolic process GO:0006259 303 0.011
actin cytoskeleton organization GO:0030036 220 0.011
monocarboxylic acid transport GO:0015718 44 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
dna repair GO:0006281 107 0.011
rho protein signal transduction GO:0007266 32 0.011
lateral inhibition GO:0046331 1 0.011
nuclear import GO:0051170 95 0.011
myeloid cell differentiation GO:0030099 233 0.011
heart morphogenesis GO:0003007 178 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of protein transport GO:0051223 163 0.011
dephosphorylation GO:0016311 129 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
histone h3 k9 acetylation GO:0043970 5 0.011
lipid localization GO:0010876 126 0.011
regulation of system process GO:0044057 200 0.011
leukocyte mediated immunity GO:0002443 174 0.010
digestive system development GO:0055123 200 0.010
regulation of binding GO:0051098 111 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
negative regulation of nervous system development GO:0051961 156 0.010
exocytosis GO:0006887 121 0.010
lymphocyte proliferation GO:0046651 164 0.010
anion transmembrane transport GO:0098656 71 0.010
glycerolipid metabolic process GO:0046486 122 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
small molecule catabolic process GO:0044282 71 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
protein localization to nucleus GO:0034504 121 0.010
amide transport GO:0042886 138 0.010
localization within membrane GO:0051668 4 0.010
myosin filament organization GO:0031033 3 0.010
regulation of response to wounding GO:1903034 189 0.010
glycoprotein metabolic process GO:0009100 116 0.010

Eif2s3y disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.025
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.015
connective tissue disease DOID:65 0 0.015
bone disease DOID:0080001 0 0.013
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
muscular disease DOID:0080000 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
muscle tissue disease DOID:66 0 0.010