Mus musculus

0 known processes

Eif5

eukaryotic translation initiation factor 5

(Aliases: D12Ertd549e,2810011H21Rik,MGC36509,MGC36374)

Eif5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.539
posttranscriptional regulation of gene expression GO:0010608 155 0.439
translation GO:0006412 93 0.329
Rat
regulation of polyamine transmembrane transport GO:1902267 5 0.329
negative regulation of protein metabolic process GO:0051248 282 0.240
aromatic compound catabolic process GO:0019439 286 0.216
cellular protein catabolic process GO:0044257 155 0.200
proteasomal protein catabolic process GO:0010498 98 0.196
modification dependent protein catabolic process GO:0019941 133 0.192
negative regulation of cellular protein metabolic process GO:0032269 247 0.188
amine metabolic process GO:0009308 45 0.176
ribosomal small subunit biogenesis GO:0042274 4 0.174
polyamine transport GO:0015846 5 0.174
purine ribonucleotide catabolic process GO:0009154 208 0.171
purine ribonucleotide metabolic process GO:0009150 290 0.166
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.161
ras protein signal transduction GO:0007265 77 0.160
gtp metabolic process GO:0046039 144 0.148
small gtpase mediated signal transduction GO:0007264 97 0.142
ribonucleoprotein complex disassembly GO:0032988 3 0.140
nucleotide catabolic process GO:0009166 217 0.130
nucleoside metabolic process GO:0009116 246 0.127
positive regulation of cellular catabolic process GO:0031331 148 0.126
regulation of protein kinase activity GO:0045859 232 0.121
rna processing GO:0006396 105 0.115
regulation of protein catabolic process GO:0042176 108 0.115
cellular amine metabolic process GO:0044106 44 0.114
polyamine biosynthetic process GO:0006596 2 0.113
regulation of translation GO:0006417 71 0.112
male meiosis i GO:0007141 16 0.110
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.110
modification dependent macromolecule catabolic process GO:0043632 133 0.097
wound healing GO:0042060 157 0.096
ribonucleoside catabolic process GO:0042454 206 0.096
organophosphate catabolic process GO:0046434 232 0.095
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.094
regulation of protein localization GO:0032880 231 0.093
gtp catabolic process GO:0006184 143 0.093
nucleoside phosphate catabolic process GO:1901292 222 0.091
spermatogenesis GO:0007283 284 0.090
nucleobase containing small molecule metabolic process GO:0055086 352 0.086
ribonucleotide catabolic process GO:0009261 208 0.084
ubiquitin dependent protein catabolic process GO:0006511 129 0.083
positive regulation of programmed cell death GO:0043068 218 0.083
purine ribonucleoside metabolic process GO:0046128 241 0.081
regulation of cell migration GO:0030334 219 0.081
nucleoside catabolic process GO:0009164 206 0.080
purine nucleoside catabolic process GO:0006152 205 0.079
regulation of cellular catabolic process GO:0031329 242 0.077
ribonucleoside triphosphate catabolic process GO:0009203 199 0.076
regulation of cell motility GO:2000145 236 0.075
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.075
purine containing compound catabolic process GO:0072523 213 0.074
purine nucleotide metabolic process GO:0006163 302 0.073
purine ribonucleoside catabolic process GO:0046130 205 0.072
regulation of cellular protein catabolic process GO:1903362 61 0.072
cellular response to cytokine stimulus GO:0071345 189 0.071
protein modification by small protein conjugation GO:0032446 187 0.069
carbohydrate derivative catabolic process GO:1901136 231 0.066
macromolecule catabolic process GO:0009057 281 0.065
regulation of organelle organization GO:0033043 289 0.064
regulation of cell cycle GO:0051726 281 0.061
chromosome segregation GO:0007059 48 0.061
purine nucleoside triphosphate catabolic process GO:0009146 203 0.060
glycosyl compound catabolic process GO:1901658 206 0.059
organic cyclic compound catabolic process GO:1901361 295 0.058
ribose phosphate metabolic process GO:0019693 291 0.058
regulation of kinase activity GO:0043549 249 0.057
guanosine containing compound metabolic process GO:1901068 144 0.056
regulation of proteolysis GO:0030162 164 0.055
cellular response to arsenic containing substance GO:0071243 4 0.053
guanosine containing compound catabolic process GO:1901069 144 0.052
regulation of mitotic cell cycle GO:0007346 126 0.052
nucleoside triphosphate catabolic process GO:0009143 205 0.051
nucleotide metabolic process GO:0009117 332 0.051
regulation of cellular component size GO:0032535 121 0.051
ribonucleoside triphosphate metabolic process GO:0009199 220 0.050
purine containing compound metabolic process GO:0072521 311 0.049
protein modification by small protein removal GO:0070646 21 0.048
mitochondrial transport GO:0006839 36 0.045
purine nucleoside triphosphate metabolic process GO:0009144 226 0.044
regulation of hydrolase activity GO:0051336 246 0.043
regulation of cell size GO:0008361 72 0.043
regulation of gtp catabolic process GO:0033124 113 0.042
positive regulation of macroautophagy GO:0016239 3 0.041
ribonucleoside metabolic process GO:0009119 245 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
glycosyl compound metabolic process GO:1901657 246 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.037
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.037
spermatid differentiation GO:0048515 115 0.037
regulation of vacuole organization GO:0044088 4 0.036
male gamete generation GO:0048232 285 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
regulation of cell cycle process GO:0010564 160 0.035
innate immune response GO:0045087 157 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.035
negative regulation of cellular component organization GO:0051129 194 0.034
organonitrogen compound catabolic process GO:1901565 264 0.033
regulation of purine nucleotide catabolic process GO:0033121 122 0.033
cellular ketone metabolic process GO:0042180 84 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
positive regulation of gtpase activity GO:0043547 85 0.033
regulation of ras gtpase activity GO:0032318 88 0.033
mitotic cell cycle GO:0000278 195 0.033
cellular response to dna damage stimulus GO:0006974 207 0.032
negative regulation of growth GO:0045926 99 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
ossification GO:0001503 216 0.032
heterocycle catabolic process GO:0046700 280 0.032
organelle fission GO:0048285 170 0.031
organic acid biosynthetic process GO:0016053 86 0.031
regulation of ras protein signal transduction GO:0046578 114 0.031
regulation of protein stability GO:0031647 52 0.031
transmembrane transport GO:0055085 412 0.031
mitotic cell cycle process GO:1903047 159 0.031
regulation of nucleotide metabolic process GO:0006140 169 0.031
protein ubiquitination GO:0016567 171 0.030
epithelium migration GO:0090132 63 0.030
monosaccharide metabolic process GO:0005996 106 0.030
carbohydrate biosynthetic process GO:0016051 74 0.030
regulation of anatomical structure size GO:0090066 178 0.030
macromolecular complex disassembly GO:0032984 43 0.030
purine nucleotide catabolic process GO:0006195 211 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
negative regulation of molecular function GO:0044092 258 0.029
meiotic cell cycle process GO:1903046 77 0.028
circulatory system process GO:0003013 197 0.028
regulation of transferase activity GO:0051338 263 0.028
nuclear division GO:0000280 158 0.028
cell fate commitment GO:0045165 210 0.028
stem cell differentiation GO:0048863 268 0.028
mrna metabolic process GO:0016071 84 0.027
organelle localization GO:0051640 179 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
skeletal system development GO:0001501 356 0.026
amine biosynthetic process GO:0009309 3 0.026
regulation of mrna processing GO:0050684 41 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
germ cell development GO:0007281 185 0.026
carbohydrate metabolic process GO:0005975 230 0.026
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.026
regulation of neuron differentiation GO:0045664 281 0.026
polyamine metabolic process GO:0006595 5 0.025
translational initiation GO:0006413 24 0.025
Rat
renal system development GO:0072001 225 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
response to arsenic containing substance GO:0046685 5 0.025
urogenital system development GO:0001655 261 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
metaphase plate congression GO:0051310 2 0.024
synaptic vesicle localization GO:0097479 59 0.024
protein autophosphorylation GO:0046777 61 0.024
multicellular organismal homeostasis GO:0048871 164 0.024
protein maturation GO:0051604 176 0.023
synaptic transmission GO:0007268 329 0.023
small molecule biosynthetic process GO:0044283 132 0.023
gluconeogenesis GO:0006094 39 0.023
establishment or maintenance of cell polarity GO:0007163 86 0.023
tissue migration GO:0090130 68 0.023
protein import GO:0017038 101 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
response to organic cyclic compound GO:0014070 198 0.022
cytoplasmic transport GO:0016482 234 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
single organism cell adhesion GO:0098602 156 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
neuronal action potential GO:0019228 54 0.022
negative regulation of phosphorylation GO:0042326 166 0.022
protein refolding GO:0042026 1 0.021
polyamine transmembrane transport GO:1902047 5 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
oocyte anterior posterior axis specification GO:0007314 2 0.021
regulation of cellular response to stress GO:0080135 159 0.021
sulfur compound metabolic process GO:0006790 100 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.021
positive regulation of kinase activity GO:0033674 155 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
response to growth factor GO:0070848 198 0.021
response to radiation GO:0009314 165 0.021
regulation of protein complex assembly GO:0043254 83 0.021
oocyte construction GO:0007308 2 0.020
protein targeting GO:0006605 143 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
regulation of response to wounding GO:1903034 189 0.020
negative regulation of proteolysis GO:0045861 74 0.020
transmission of nerve impulse GO:0019226 76 0.020
regulation of cell projection organization GO:0031344 206 0.020
ribonucleoprotein complex subunit organization GO:0071826 28 0.020
protein processing GO:0016485 163 0.019
chromatin organization GO:0006325 206 0.019
regulation of protein maturation GO:1903317 96 0.019
protein catabolic process GO:0030163 221 0.019
meiotic cell cycle GO:0051321 122 0.019
regulation of metal ion transport GO:0010959 106 0.019
regulation of proteasomal protein catabolic process GO:0061136 46 0.019
positive regulation of ras gtpase activity GO:0032320 65 0.018
multi multicellular organism process GO:0044706 109 0.018
lateral inhibition GO:0046331 1 0.018
asymmetric stem cell division GO:0098722 3 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.018
organelle disassembly GO:1903008 2 0.018
maternal determination of anterior posterior axis embryo GO:0008358 2 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
regulation of protein processing GO:0070613 96 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
carbohydrate homeostasis GO:0033500 128 0.018
regulation of transmembrane transport GO:0034762 128 0.017
protein localization to organelle GO:0033365 185 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
response to temperature stimulus GO:0009266 55 0.017
spliceosomal complex disassembly GO:0000390 1 0.017
regulation of cellular response to growth factor stimulus GO:0090287 82 0.017
protein digestion GO:0044256 1 0.017
dna metabolic process GO:0006259 303 0.017
membrane organization GO:0061024 245 0.017
kidney development GO:0001822 213 0.017
negative regulation of protein processing GO:0010955 79 0.016
cell adhesion GO:0007155 329 0.016
rna interference GO:0016246 2 0.016
regionalization GO:0003002 337 0.016
pole plasm assembly GO:0007315 2 0.016
positive regulation of transferase activity GO:0051347 167 0.016
central nervous system neuron differentiation GO:0021953 162 0.016
protein import into nucleus GO:0006606 95 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
genitalia development GO:0048806 37 0.016
action potential GO:0001508 78 0.016
histone modification GO:0016570 159 0.016
rap protein signal transduction GO:0032486 3 0.016
cell growth GO:0016049 130 0.016
negative regulation of protein catabolic process GO:0042177 36 0.016
negative regulation of protein maturation GO:1903318 79 0.016
intracellular protein transport GO:0006886 204 0.016
striated muscle tissue development GO:0014706 293 0.016
multicellular organismal protein metabolic process GO:0044268 2 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
multicellular organismal macromolecule catabolic process GO:0044266 1 0.015
lipid transport GO:0006869 98 0.015
peptidyl amino acid modification GO:0018193 336 0.015
nonribosomal peptide biosynthetic process GO:0019184 5 0.015
asymmetric neuroblast division GO:0055059 1 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
mitochondrion organization GO:0007005 134 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
response to nutrient levels GO:0031667 109 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.014
regulation of secretion GO:0051046 274 0.014
stem cell development GO:0048864 219 0.014
cellular homeostasis GO:0019725 240 0.014
muscle tissue development GO:0060537 308 0.014
cellular lipid metabolic process GO:0044255 323 0.014
mesenchyme development GO:0060485 152 0.014
microtubule based process GO:0007017 236 0.014
establishment of vesicle localization GO:0051650 81 0.014
single fertilization GO:0007338 82 0.014
regulation of peptidase activity GO:0052547 96 0.014
dendrite development GO:0016358 115 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
meiosis i GO:0007127 60 0.013
regulation of cell shape GO:0008360 39 0.013
response to uv GO:0009411 44 0.013
intracellular mrna localization GO:0008298 4 0.013
cation transport GO:0006812 399 0.013
regulation of membrane potential GO:0042391 192 0.013
gene silencing by rna GO:0031047 19 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
response to heat GO:0009408 27 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
regulation of mrna metabolic process GO:1903311 43 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
dna repair GO:0006281 107 0.013
dephosphorylation GO:0016311 129 0.013
oocyte axis specification GO:0007309 2 0.013
skeletal system morphogenesis GO:0048705 203 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
positive regulation of proteolysis GO:0045862 85 0.012
cell division GO:0051301 120 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
digestive tract morphogenesis GO:0048546 147 0.012
body morphogenesis GO:0010171 45 0.012
putrescine metabolic process GO:0009445 1 0.012
ribosome biogenesis GO:0042254 20 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
dna replication GO:0006260 52 0.012
establishment of organelle localization GO:0051656 122 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
skeletal muscle organ development GO:0060538 163 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
positive regulation of organelle organization GO:0010638 128 0.012
cell maturation GO:0048469 127 0.012
lymphocyte proliferation GO:0046651 164 0.012
regulation of protein targeting GO:1903533 61 0.012
skin development GO:0043588 220 0.012
regulation of intracellular transport GO:0032386 159 0.012
response to light stimulus GO:0009416 135 0.012
cellular protein complex assembly GO:0043623 116 0.011
lung development GO:0030324 164 0.011
nuclear import GO:0051170 95 0.011
vesicle localization GO:0051648 86 0.011
non canonical wnt signaling pathway GO:0035567 33 0.011
n terminal protein amino acid modification GO:0031365 6 0.011
protein acylation GO:0043543 64 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
internal protein amino acid acetylation GO:0006475 42 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
glucose metabolic process GO:0006006 92 0.011
negative regulation of cellular protein catabolic process GO:1903363 22 0.011
centrosome separation GO:0051299 4 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
regulation of homeostatic process GO:0032844 182 0.011
endothelial cell migration GO:0043542 44 0.011
regulation of cell adhesion GO:0030155 154 0.011
cell type specific apoptotic process GO:0097285 268 0.011
ameboidal type cell migration GO:0001667 128 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
fatty acid metabolic process GO:0006631 121 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
multicellular organismal protein catabolic process GO:0044254 1 0.010
blood vessel morphogenesis GO:0048514 285 0.010
positive regulation of lamellipodium organization GO:1902745 3 0.010
regulation of secretion by cell GO:1903530 249 0.010
adult locomotory behavior GO:0008344 91 0.010
negative regulation of cell development GO:0010721 169 0.010
regulation of nuclear division GO:0051783 56 0.010
alpha amino acid metabolic process GO:1901605 59 0.010
positive regulation of translation GO:0045727 19 0.010

Eif5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
myopathy DOID:423 0 0.024
muscular disease DOID:0080000 0 0.024
muscle tissue disease DOID:66 0 0.024
central nervous system disease DOID:331 0 0.015
nervous system disease DOID:863 0 0.015
muscular dystrophy DOID:9884 0 0.013
limb girdle muscular dystrophy DOID:11724 0 0.013