Mus musculus

0 known processes

Eif6

eukaryotic translation initiation factor 6

(Aliases: eIF-6,p27(BBP),p27BBP,Itgb4bp,imc-415,1110004P11,CAB,AA408895)

Eif6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.261
organonitrogen compound catabolic process GO:1901565 264 0.239
nucleoside triphosphate metabolic process GO:0009141 230 0.228
purine nucleoside metabolic process GO:0042278 241 0.138
regulation of cellular amine metabolic process GO:0033238 20 0.137
cellular response to dna damage stimulus GO:0006974 207 0.134
purine nucleoside catabolic process GO:0006152 205 0.119
glycosyl compound catabolic process GO:1901658 206 0.111
aromatic compound catabolic process GO:0019439 286 0.105
purine nucleotide metabolic process GO:0006163 302 0.104
cellular amino acid metabolic process GO:0006520 103 0.102
purine containing compound metabolic process GO:0072521 311 0.101
rna processing GO:0006396 105 0.097
nucleoside metabolic process GO:0009116 246 0.095
purine ribonucleotide metabolic process GO:0009150 290 0.095
cellular amine metabolic process GO:0044106 44 0.092
ribose phosphate metabolic process GO:0019693 291 0.091
amine metabolic process GO:0009308 45 0.088
cellular ion homeostasis GO:0006873 165 0.087
heterocycle catabolic process GO:0046700 280 0.086
development of primary sexual characteristics GO:0045137 143 0.083
purine ribonucleoside catabolic process GO:0046130 205 0.082
purine nucleoside triphosphate catabolic process GO:0009146 203 0.081
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
purine containing compound catabolic process GO:0072523 213 0.075
organophosphate catabolic process GO:0046434 232 0.074
ribonucleoside metabolic process GO:0009119 245 0.074
organic cyclic compound catabolic process GO:1901361 295 0.073
ribonucleoside triphosphate metabolic process GO:0009199 220 0.073
regulation of cellular ketone metabolic process GO:0010565 66 0.071
cellular homeostasis GO:0019725 240 0.070
ribonucleotide metabolic process GO:0009259 291 0.069
cellular nitrogen compound catabolic process GO:0044270 280 0.068
positive regulation of cellular amine metabolic process GO:0033240 5 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
myosin filament organization GO:0031033 3 0.068
nucleoside phosphate catabolic process GO:1901292 222 0.067
cellular chemical homeostasis GO:0055082 215 0.066
regulation of cell cycle process GO:0010564 160 0.066
macromolecule catabolic process GO:0009057 281 0.064
purine ribonucleoside metabolic process GO:0046128 241 0.064
glycosyl compound metabolic process GO:1901657 246 0.064
mitotic cell cycle GO:0000278 195 0.064
purine nucleotide catabolic process GO:0006195 211 0.061
purine nucleoside triphosphate metabolic process GO:0009144 226 0.060
gonad development GO:0008406 141 0.059
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.059
nucleoside triphosphate catabolic process GO:0009143 205 0.058
cellular ketone metabolic process GO:0042180 84 0.058
purine ribonucleotide catabolic process GO:0009154 208 0.057
nucleoside catabolic process GO:0009164 206 0.057
actin filament polymerization GO:0030041 44 0.057
protein modification by small protein conjugation GO:0032446 187 0.056
regulation of purine nucleotide catabolic process GO:0033121 122 0.055
ribonucleoside catabolic process GO:0042454 206 0.054
organophosphate biosynthetic process GO:0090407 122 0.053
t cell activation GO:0042110 289 0.051
nucleotide catabolic process GO:0009166 217 0.051
ribonucleotide catabolic process GO:0009261 208 0.050
positive regulation of nucleotide catabolic process GO:0030813 88 0.050
response to organonitrogen compound GO:0010243 246 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.050
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.047
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.046
iron sulfur cluster assembly GO:0016226 3 0.045
nucleotide metabolic process GO:0009117 332 0.044
positive regulation of protein modification process GO:0031401 299 0.044
striated muscle myosin thick filament assembly GO:0071688 1 0.044
negative regulation of cellular component organization GO:0051129 194 0.044
ovarian follicle development GO:0001541 40 0.044
rhythmic process GO:0048511 174 0.043
myeloid cell differentiation GO:0030099 233 0.043
dna metabolic process GO:0006259 303 0.043
regulation of nucleotide metabolic process GO:0006140 169 0.042
cellular macromolecule catabolic process GO:0044265 206 0.041
cation homeostasis GO:0055080 212 0.041
ras protein signal transduction GO:0007265 77 0.041
gland development GO:0048732 330 0.041
atp catabolic process GO:0006200 55 0.041
small gtpase mediated signal transduction GO:0007264 97 0.040
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.039
regulation of cell cycle GO:0051726 281 0.039
lymphocyte differentiation GO:0030098 242 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.039
negative regulation of cellular amine metabolic process GO:0033239 1 0.039
ribonucleoside monophosphate catabolic process GO:0009158 57 0.038
regulation of homeostatic process GO:0032844 182 0.038
organelle fission GO:0048285 170 0.038
nucleoside monophosphate metabolic process GO:0009123 85 0.038
nadph regeneration GO:0006740 2 0.037
trna wobble base modification GO:0002097 2 0.037
myosin filament assembly GO:0031034 2 0.037
regulation of membrane potential GO:0042391 192 0.036
epithelial tube morphogenesis GO:0060562 303 0.035
peptidyl amino acid modification GO:0018193 336 0.034
cellular response to cytokine stimulus GO:0071345 189 0.034
positive regulation of gtpase activity GO:0043547 85 0.034
protein catabolic process GO:0030163 221 0.033
oxidation reduction process GO:0055114 342 0.032
ion transmembrane transport GO:0034220 361 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
mrna splicing via spliceosome GO:0000398 43 0.032
translation GO:0006412 93 0.031
ossification GO:0001503 216 0.031
transmembrane transport GO:0055085 412 0.031
regulation of cellular component size GO:0032535 121 0.031
negative regulation of protein metabolic process GO:0051248 282 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
regulation of organelle organization GO:0033043 289 0.030
regulation of ion transport GO:0043269 215 0.030
trna wobble uridine modification GO:0002098 2 0.030
rna splicing GO:0008380 54 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.030
atp metabolic process GO:0046034 75 0.029
positive regulation of nucleoside metabolic process GO:0045979 91 0.029
endocytosis GO:0006897 168 0.029
Worm
regulation of mrna splicing via spliceosome GO:0048024 32 0.028
metal ion homeostasis GO:0055065 189 0.028
regulation of nucleoside metabolic process GO:0009118 130 0.028
cation transport GO:0006812 399 0.028
meiotic cell cycle GO:0051321 122 0.028
reactive oxygen species metabolic process GO:0072593 84 0.027
actin polymerization or depolymerization GO:0008154 54 0.026
male gamete generation GO:0048232 285 0.026
regulation of hydrolase activity GO:0051336 246 0.026
rna splicing via transesterification reactions GO:0000375 43 0.026
dephosphorylation GO:0016311 129 0.026
positive regulation of cellular catabolic process GO:0031331 148 0.026
protein polymerization GO:0051258 57 0.026
microtubule cytoskeleton organization GO:0000226 157 0.025
purine nucleoside monophosphate catabolic process GO:0009128 58 0.025
nitrogen compound transport GO:0071705 271 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
sensory organ morphogenesis GO:0090596 242 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.025
mitotic cell cycle process GO:1903047 159 0.025
leukocyte differentiation GO:0002521 342 0.024
apoptotic signaling pathway GO:0097190 306 0.024
extracellular matrix organization GO:0030198 147 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
iron ion homeostasis GO:0055072 36 0.024
nuclear division GO:0000280 158 0.024
anion transport GO:0006820 177 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
mrna metabolic process GO:0016071 84 0.023
germ cell development GO:0007281 185 0.023
nucleoside monophosphate catabolic process GO:0009125 59 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
trna modification GO:0006400 9 0.022
gtp metabolic process GO:0046039 144 0.022
selenium compound metabolic process GO:0001887 3 0.022
regulation of cell division GO:0051302 76 0.022
cell division GO:0051301 120 0.022
divalent metal ion transport GO:0070838 172 0.021
female sex differentiation GO:0046660 84 0.021
regulation of protein localization GO:0032880 231 0.021
calcium ion transport GO:0006816 159 0.021
camera type eye development GO:0043010 266 0.021
negative regulation of molecular function GO:0044092 258 0.021
maturation of lsu rrna GO:0000470 1 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
regulation of translation GO:0006417 71 0.021
positive regulation of cellular component biogenesis GO:0044089 94 0.021
translational initiation GO:0006413 24 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
regulation of actin filament polymerization GO:0030833 38 0.020
glucose homeostasis GO:0042593 128 0.020
response to extracellular stimulus GO:0009991 127 0.020
morphogenesis of a branching structure GO:0001763 203 0.019
mapk cascade GO:0000165 281 0.019
morphogenesis of a branching epithelium GO:0061138 193 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
actin cytoskeleton organization GO:0030036 220 0.019
regulation of cell motility GO:2000145 236 0.019
regionalization GO:0003002 337 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
modification dependent protein catabolic process GO:0019941 133 0.018
membrane organization GO:0061024 245 0.018
regulation of anatomical structure size GO:0090066 178 0.018
t cell differentiation GO:0030217 174 0.018
female gonad development GO:0008585 71 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
muscle cell differentiation GO:0042692 261 0.018
retina development in camera type eye GO:0060041 119 0.018
sequestering of calcium ion GO:0051208 18 0.018
spermatogenesis GO:0007283 284 0.018
mrna processing GO:0006397 63 0.018
oocyte construction GO:0007308 2 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
ovulation cycle GO:0042698 59 0.017
release of cytochrome c from mitochondria GO:0001836 23 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
regulation of cell activation GO:0050865 289 0.017
leukocyte proliferation GO:0070661 172 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
protein maturation GO:0051604 176 0.017
divalent inorganic cation transport GO:0072511 178 0.017
cellular lipid metabolic process GO:0044255 323 0.016
branching morphogenesis of an epithelial tube GO:0048754 159 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
ribosomal small subunit biogenesis GO:0042274 4 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
arp2 3 complex mediated actin nucleation GO:0034314 3 0.016
cytoplasmic transport GO:0016482 234 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
molting cycle GO:0042303 90 0.016
striated muscle tissue development GO:0014706 293 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
regulation of t cell activation GO:0050863 170 0.016
respiratory system development GO:0060541 190 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.016
forebrain development GO:0030900 302 0.016
protein ubiquitination GO:0016567 171 0.015
negative regulation of cell cycle GO:0045786 123 0.015
mitotic cytokinesis GO:0000281 4 0.015
dna dealkylation GO:0035510 11 0.015
ear morphogenesis GO:0042471 118 0.015
dna repair GO:0006281 107 0.015
cellular response to lipid GO:0071396 145 0.015
transmission of nerve impulse GO:0019226 76 0.015
axon guidance GO:0007411 141 0.015
gtp catabolic process GO:0006184 143 0.015
positive regulation of actin filament polymerization GO:0030838 26 0.015
sequestering of metal ion GO:0051238 19 0.015
calcium ion homeostasis GO:0055074 127 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
response to nutrient levels GO:0031667 109 0.015
digestive tract development GO:0048565 190 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
regulation of actin nucleation GO:0051125 4 0.015
cell adhesion GO:0007155 329 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
female gamete generation GO:0007292 74 0.015
response to acid chemical GO:0001101 111 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
homeostasis of number of cells GO:0048872 210 0.015
lymphocyte proliferation GO:0046651 164 0.014
positive regulation of cell death GO:0010942 224 0.014
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
rac protein signal transduction GO:0016601 13 0.014
organelle localization GO:0051640 179 0.014
photoreceptor cell development GO:0042461 40 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
oogenesis GO:0048477 56 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
cellular transition metal ion homeostasis GO:0046916 32 0.014
positive regulation of ion transport GO:0043270 65 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
cytokinetic process GO:0032506 2 0.014
digestive system development GO:0055123 200 0.014
regulation of transferase activity GO:0051338 263 0.014
development of primary female sexual characteristics GO:0046545 73 0.014
protein localization to organelle GO:0033365 185 0.014
dna recombination GO:0006310 92 0.013
sensory perception GO:0007600 245 0.013
glycoprotein metabolic process GO:0009100 116 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
monosaccharide metabolic process GO:0005996 106 0.013
spermatid differentiation GO:0048515 115 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
epithelial cell proliferation GO:0050673 174 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
synaptic transmission GO:0007268 329 0.013
striated muscle cell development GO:0055002 125 0.013
transition metal ion homeostasis GO:0055076 54 0.013
metallo sulfur cluster assembly GO:0031163 3 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
endomembrane system organization GO:0010256 147 0.013
single organism cell adhesion GO:0098602 156 0.013
thymus development GO:0048538 41 0.013
cell type specific apoptotic process GO:0097285 268 0.013
neuron death GO:0070997 154 0.013
myeloid cell homeostasis GO:0002262 114 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
immune effector process GO:0002252 321 0.013
response to light stimulus GO:0009416 135 0.013
purine nucleotide biosynthetic process GO:0006164 65 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of protein catabolic process GO:0042176 108 0.012
mitochondrial fusion GO:0008053 9 0.012
blood vessel morphogenesis GO:0048514 285 0.012
eye photoreceptor cell differentiation GO:0001754 41 0.012
trna processing GO:0008033 11 0.012
regulation of metal ion transport GO:0010959 106 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
positive regulation of growth hormone receptor signaling pathway GO:0060399 3 0.012
rho protein signal transduction GO:0007266 32 0.012
immune response activating signal transduction GO:0002757 116 0.012
skeletal system development GO:0001501 356 0.012
response to organic cyclic compound GO:0014070 198 0.012
ncrna processing GO:0034470 26 0.012
gastrulation GO:0007369 116 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.012
negative regulation of cell development GO:0010721 169 0.012
carbohydrate metabolic process GO:0005975 230 0.012
cation transmembrane transport GO:0098655 266 0.012
neural precursor cell proliferation GO:0061351 121 0.012
regulation of secretion GO:0051046 274 0.012
maintenance of location GO:0051235 89 0.012
response to inorganic substance GO:0010035 96 0.012
notch signaling pathway GO:0007219 71 0.012
extracellular structure organization GO:0043062 148 0.012
gliogenesis GO:0042063 141 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
antigen receptor mediated signaling pathway GO:0050851 64 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
connective tissue development GO:0061448 179 0.012
cell maturation GO:0048469 127 0.012
regulation of mapk cascade GO:0043408 248 0.012
activation of immune response GO:0002253 138 0.012
regulation of protein oligomerization GO:0032459 4 0.012
cell communication by chemical coupling GO:0010643 2 0.012
positive regulation of cell cycle GO:0045787 92 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
heart morphogenesis GO:0003007 178 0.011
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.011
t cell differentiation in thymus GO:0033077 77 0.011
lymphocyte apoptotic process GO:0070227 54 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
cellular amide metabolic process GO:0043603 58 0.011
cellular protein complex assembly GO:0043623 116 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.011
glial cell differentiation GO:0010001 131 0.011
regulation of peptidase activity GO:0052547 96 0.011
cytoplasmic translational initiation GO:0002183 3 0.011
establishment of rna localization GO:0051236 18 0.011
microtubule based process GO:0007017 236 0.011
actin filament organization GO:0007015 113 0.011
regulation of secretion by cell GO:1903530 249 0.011
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
maturation of ssu rrna GO:0030490 1 0.011
response to radiation GO:0009314 165 0.011
epithelial cell development GO:0002064 159 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
cellular response to hexose stimulus GO:0071331 47 0.011
angiogenesis GO:0001525 201 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
meiotic nuclear division GO:0007126 115 0.011
protein localization to membrane GO:0072657 108 0.011
digestive tract morphogenesis GO:0048546 147 0.011
positive regulation of dna repair GO:0045739 3 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
organism emergence from protective structure GO:0071684 4 0.010
defense response to other organism GO:0098542 197 0.010
positive regulation of protein oligomerization GO:0032461 4 0.010
positive regulation of cell development GO:0010720 237 0.010
nuclear transport GO:0051169 139 0.010
positive regulation of cell activation GO:0050867 158 0.010
carbohydrate homeostasis GO:0033500 128 0.010
negative regulation of cell motility GO:2000146 61 0.010
meiotic cell cycle process GO:1903046 77 0.010
t cell proliferation GO:0042098 120 0.010
response to peptide hormone GO:0043434 127 0.010
axonogenesis GO:0007409 274 0.010

Eif6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.037
disease of anatomical entity DOID:7 0 0.037
organ system cancer DOID:0050686 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
cancer DOID:162 0 0.029
large intestine cancer DOID:5672 0 0.017
colon cancer DOID:219 0 0.017
intestinal cancer DOID:10155 0 0.017
gastrointestinal system cancer DOID:3119 0 0.017
colorectal cancer DOID:9256 0 0.017
neuropathy DOID:870 0 0.016
sensory system disease DOID:0050155 0 0.011